Explanipedia

Extracellular vesicle miR-425-5p promotes visceral fat reduction via DACT1 suppression in SGLT2i-treated diabetes Open

Jae‐Hyung Park, Thi Tuyet Nhung Nguyen, Hye Min Shim, Yun‐Ui Bae, Gyeong Im Yu , et al. · 2025

Objective In type 2 diabetes (T2D), plasma-derived extracellular vesicle (EV)-microRNAs (miRNAs) contribute to insulin resistance and β-cell dysfunction. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) lower blood glucose by promoting u…

ANKRD1 Promotes Breast Cancer Metastasis by Activating NF-κB-MAGE-A6 Pathway Open

Penchatr Diskul‐Na‐Ayudthaya, Seon Joo Bae, Yun‐Ui Bae, Ngu Trinh Van, Wootae Kim , et al. · 2024

Early detection and surgical excision of tumors have helped improve the survival rate of patients with breast cancer. However, patients with metastatic cancer typically have a poor prognosis. In this study, we propose that ANKRD1 promotes …

Circulating miRNAs in extracellular vesicles related to treatment response in patients with idiopathic membranous nephropathy Open

In O Sun, Yun‐Ui Bae, Haekyung Lee, Hyoungnae Kim, Jin Seok Jeon , et al. · 2022

Circulating miRNAs in extracellular vesicles related to treatment response in patients with idiopathic membranous nephropathy Open

In O Sun, Yun‐Ui Bae, Haekyung Lee, Hyoungnae Kim, Jin Seok Jeon , et al. · 2022

Background : Extracellular vesicle (EV)-microRNAs (miRNAs) are potential biomarkers for various renal diseases. This study attempted to identify the circulating EV-miRNA signature not only for discriminating idiopathic membranous nephropat…

Weight Change Alters the Small RNA Profile of Urinary Extracellular Vesicles in Obesity Open

Dughyun Choi, Sewon Kim, Jeyoung Woo, Haekyung Lee, Hyoungnae Kim , et al. · 2022

Introduction: Various kidney diseases reportedly show different urinary extracellular vesicle (EV) RNA profiles. Although obesity is one of the main causes of chronic kidney disease, the expression pattern of urinary EV RNA i…

Association of Protein Z with Prediabetes and Type 2 Diabetes (Endocrinol Metab 2021;36:637-46, Yun-Ui Bae et al.) Open

Ji Hong You, Yun‐Ui Bae, Ho‐Chan Cho · 2021

See the Original "Association of Protein Z with Prediabetes and Type 2 Diabetes" in Volume 36 on page 637.

Association of Protein Z with Prediabetes and Type 2 Diabetes Open

Yun‐Ui Bae, Ji Hong You, Nan Hee Cho, Eun-Jung Kim, Hye Min Shim , et al. · 2021

PROZ levels were associated with prediabetes and T2DM. We suggest that PROZ may be a promising biomarker for the early detection of prediabetes. Further large-scale studies are needed to evaluate the relationship and mechanism between PROZ…

Effect of diabetes on exosomal miRNA profile in patients with obesity Open

Hyoshik Kim, Yun‐Ui Bae, Haekyung Lee, Hyoungnae Kim, Jin Seok Jeon , et al. · 2020

Introduction Obesity is a risk factor for type 2 diabetes mellitus (T2DM) and cardiovascular disease. T2DM increases the risk of cardiovascular-related death. We investigated changes in circulating exosomal microRNA (miRNA) profiles in pat…

microRNA in Extracellular Vesicles Released by Damaged Podocytes Promote Apoptosis of Renal Tubular Epithelial Cells Open

Jin Seok Jeon, Eunbit Kim, Yun‐Ui Bae, Won Mi Yang, Haekyung Lee , et al. · 2020

Tubular injury and fibrosis are associated with progressive kidney dysfunction in advanced glomerular disease. Glomerulotubular crosstalk is thought to contribute to tubular injury. microRNAs (miRNAs) in extracellular vesicles (EVs) can mo…

The circulating exosomal microRNAs related to albuminuria in patients with diabetic nephropathy Open

Hyoungnae Kim, Yun‐Ui Bae, Jin Seok Jeon, Hyunjin Noh, Hyeong Kyu Park , et al. · 2019

SUN-156 Exosomal MicroRNA Profile in Korean Obese Subjects with Prediabetes and Those with Type 2 Diabetes Mellitus Open

Hyeong-Kyu Park, Yun‐Ui Bae, Soon‐Hyo Kwon, Jae-Hyuk Lee, Hyejeong Kim , et al. · 2019

MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. Recent evidence has shown that altered expression of miRNAs is associated with various pathophysiological processes, including type 2 diabetes mellitus (T2DM), can…

Bariatric Surgery Alters microRNA Content of Circulating Exosomes in Patients with Obesity Open

Yun‐Ui Bae, Yong-Jin Kim, Haekyung Lee, Hyoungnae Kim, Jin Seok Jeon , et al. · 2019

Objective Exosomal microRNAs (miRNAs) are potential biomarkers for obesity, in which they regulate biological processes. Bariatric surgery has health benefits for patients with obesity; however, the mechanisms of these benefits are not cle…

Promotion of tumor progression and cancer stemness by MUC15 in thyroid cancer via the GPCR/ERK and integrin-FAK signaling pathways Open

Cheol-Won Choi, Nguyen Thi Thao Tran, Van Ngu Trinh, Sae Woong Park, Min Song , et al. · 2018

Thyroid cancer is the fifth most common cancer diagnosed in women worldwide. Notwithstanding advancements in the prognosis and treatment of thyroid cancer, 10–20% of thyroid cancer patients develops chemotherapeutic resistance and experien…

mirRICH, a simple method to enrich the small RNA fraction from over-dried RNA pellets Open

Cheol-Won Choi, Seulgi Yoon, Hyesu Moon, Yun‐Ui Bae, Chae-Bin Kim , et al. · 2018

Techniques to isolate the small RNA fraction (<200nt) by column-based methods are commercially available. However, their use is limited because of the relatively high cost. We found that large RNA molecules, including mRNAs and rRNAs, are …

P343 Oncoplastic surgery for inner quadrant breast cancer: a modified dermoglandular rotation flap Open

S. Lee, J. Lee, Yong Sik Jung, Yun‐Ui Bae · 2015

had NSLN metastasis, while 14 patients were found to have ITC in SLN; none of them had NSLN metastasis. Multivariate analysis found that the number of SLN harboring micrometastasis is the only independent risk factor for NSLN metastasis in…

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