Yan Deng
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View article: Comparison of <scp>5 T</scp> and <scp>3 T</scp> Biparametric <scp>MRI</scp> for Clinically Suspected Prostate Cancer: Image Quality, Lesion Visualization, and Artifacts
Comparison of <span>5 T</span> and <span>3 T</span> Biparametric <span>MRI</span> for Clinically Suspected Prostate Cancer: Image Quality, Lesion Visualization, and Artifacts Open
Background Biparametric MRI (bpMRI) is important for prostate cancer (PCa) diagnosis. Higher field strength at 5 T may improve image quality versus 3 T, but clinical value remains unclear. Purpose To compare image quality, imaging artifact…
View article: The efficacy, safety, and pharmacokinetics/pharmacodynamics of telitacicept following efgartigimod in generalized myasthenia gravis: protocol of a randomized controlled trial
The efficacy, safety, and pharmacokinetics/pharmacodynamics of telitacicept following efgartigimod in generalized myasthenia gravis: protocol of a randomized controlled trial Open
Introduction Several biologic agents have emerged as novel therapeutic options for patients with generalized myasthenia gravis (gMG); however, no clinical studies have yet explored the efficacy and safety of sequential biologic therapy in …
View article: Ultrasensitive, label-free voltammetric detection of bis(2-ethylhexyl) phthalate based on poly-l-lysine/black phosphorus-porous graphene‑silver nanocomposite
Ultrasensitive, label-free voltammetric detection of bis(2-ethylhexyl) phthalate based on poly-l-lysine/black phosphorus-porous graphene‑silver nanocomposite Open
Di(2-ethylhexyl) phthalate (DEHP), a widely used plasticizer and known endocrine disruptor, has the potential to migrate through the food chain and accumulate in the human body, thereby posing significant risks to human health. Therefore, …
View article: Impact of gastric tube width and dietary habits on postoperative reflux in esophageal cancer
Impact of gastric tube width and dietary habits on postoperative reflux in esophageal cancer Open
View article: Development of human resources in malaria microscopy during and after the malaria elimination phase in China
Development of human resources in malaria microscopy during and after the malaria elimination phase in China Open
Introduction Under the context of sustained low malaria incidence in China, maintaining an adequate number of qualified microscopists remains a critical component to ensure and sustain the success of malaria elimination. Therefore, this pa…
View article: A Social Force Model for Companion Groups Considering Relative-Weight Attraction
A Social Force Model for Companion Groups Considering Relative-Weight Attraction Open
This paper introduces an improved social force model for companion group that incorporates relative weight attraction. Based on the traditional social force model, the interaction forces among individuals within leader-follower groups are …
View article: Association between dietary index for gut microbiota and kidney stones with body mass index as a potential mediator: A cross-sectional study
Association between dietary index for gut microbiota and kidney stones with body mass index as a potential mediator: A cross-sectional study Open
Dietary habits are associated with kidney stones, yet the association between the newly proposed dietary index for gut microbiota (DI-GM), which assesses the impact of diet on gut microbiota health, and kidney stones remains unclear. This …
View article: Genome-Wide Identification of the Growth-Regulating Factor (GRF) Gene Family in Three Cymbidium Species and Expression Patterns in C. goeringii
Genome-Wide Identification of the Growth-Regulating Factor (GRF) Gene Family in Three Cymbidium Species and Expression Patterns in C. goeringii Open
The GRF (Growth-Regulating Factor) gene family has indispensable regulatory functions in the morphological and physiological development of plants. Nonetheless, comprehensive investigations of GRF gene family members and their functional r…
View article: Protective effect of ammonium trichloride tellurate (AS101) on ovarian injury induced by chemotherapy drug doxorubicin in rats
Protective effect of ammonium trichloride tellurate (AS101) on ovarian injury induced by chemotherapy drug doxorubicin in rats Open
View article: Combined metformin and exenatide versus only metformin treatments in polycystic ovary syndrome with abdominal obesity and network pharmacology of gene expression: evidence from a randomized clinical trial
Combined metformin and exenatide versus only metformin treatments in polycystic ovary syndrome with abdominal obesity and network pharmacology of gene expression: evidence from a randomized clinical trial Open
Objective: To evaluate (1) the metabolic and endocrine effects of metformin combined with exenatide versus only metformin treatments in patients with polycystic ovary syndrome (PCOS) and abdominal obesity (AO) and (2) to determine the mole…
View article: Is integrative therapy of traditional Chinese medicine and progesterone capsule more effective than monotherapies in oligomenorrhea and hypomenorrhea? Evidence based on a multi-center randomized controlled trial and metabolomic profile
Is integrative therapy of traditional Chinese medicine and progesterone capsule more effective than monotherapies in oligomenorrhea and hypomenorrhea? Evidence based on a multi-center randomized controlled trial and metabolomic profile Open
Background and Objectives Oligomenorrhea and hypomenorrhea were common conditions in outpatient visit which affected child-bearing aged women, and the conventional progesterone treatment has been related to several side effect and contradi…
View article: Back Cover: Turning on the Heat by Cocrystal Engineering: The Rise of Organic Charge Transfer Photothermal Cocrystals as an Emerging Therapeutic Frontier in Biomedical Application
Back Cover: Turning on the Heat by Cocrystal Engineering: The Rise of Organic Charge Transfer Photothermal Cocrystals as an Emerging Therapeutic Frontier in Biomedical Application Open
View article: Environmental trade-offs and productivity gains through sustainable nitrogen use in an intensive high-input sugarcane production system in China
Environmental trade-offs and productivity gains through sustainable nitrogen use in an intensive high-input sugarcane production system in China Open
View article: Minimal Residual Disease Detection: Implications for Clinical Diagnosis and Cancer Patient Treatment
Minimal Residual Disease Detection: Implications for Clinical Diagnosis and Cancer Patient Treatment Open
Minimal residual disease (MRD) serves as a pivotal biomarker for the clinical diagnosis and subsequent treatment of cancer patients. In hematological malignancies, MRD pose an increasingly serious threat to the health of Chinese people. Ac…
View article: Turning on the Heat by Cocrystal Engineering: The Rise of Organic Charge Transfer Photothermal Cocrystals as an Emerging Therapeutic Frontier in Biomedical Application
Turning on the Heat by Cocrystal Engineering: The Rise of Organic Charge Transfer Photothermal Cocrystals as an Emerging Therapeutic Frontier in Biomedical Application Open
The field of molecular charge transfer cocrystals (CTCs) has advanced rapidly in recent years, with much work focused on their use in optoelectronic devices, photoacoustic imaging, photothermal therapy (PTT), optical waveguides, seawater d…
View article: Poliovirus shedding after sequential immunization of Sabin-strain inactivated polio vaccines and oral attenuated polio vaccines
Poliovirus shedding after sequential immunization of Sabin-strain inactivated polio vaccines and oral attenuated polio vaccines Open
View article: A Novel Prediction Model for the Sales Cycle of Second-Hand Houses Based on the Hybrid Kernel Extreme Learning Machine Optimized Using the Improved Crested Porcupine Optimizer
A Novel Prediction Model for the Sales Cycle of Second-Hand Houses Based on the Hybrid Kernel Extreme Learning Machine Optimized Using the Improved Crested Porcupine Optimizer Open
Second-hand housing transactions are an important part of the housing market. Due to the dual influence of location and price, the sales cycle of second-hand housing has shown significant diversity. As a result, when residents sell or buy …
View article: Multifactorial construction of low‐grade and high‐grade endometrial cancer recurrence prediction models
Multifactorial construction of low‐grade and high‐grade endometrial cancer recurrence prediction models Open
Objective To analyze independent risk factors for endometrial cancer (EC), a common female cancer globally, and construct individualized prediction models for EC recurrence. Methods The EC patients from the medical record system were divid…
View article: Ultrasensitive, Label-Free Voltammetric Detection of Bis(2-Ethylhexyl) Phthalate Based on Poly-L-Lysine/Black Phosphorus-Porous Graphene-Silver Nanocomposite
Ultrasensitive, Label-Free Voltammetric Detection of Bis(2-Ethylhexyl) Phthalate Based on Poly-L-Lysine/Black Phosphorus-Porous Graphene-Silver Nanocomposite Open
View article: Biometal-Organic Frameworks based Quenching Electrochemiluminescence Strategy for CA19-9 Detection
Biometal-Organic Frameworks based Quenching Electrochemiluminescence Strategy for CA19-9 Detection Open
View article: Amoxicillin-associated hemorrhagic colitis: A case report and literature review
Amoxicillin-associated hemorrhagic colitis: A case report and literature review Open
Rationale: Antibiotic-associated hemorrhagic colitis (AAHC) is a special type of antibiotic-associated colitis. Due to the increased use of antibiotics, especially amoxicillin, which is commonly used in clinical practice, the incidence of …
View article: Fine mapping and candidate gene analysis of the major QTL qSW-A03 for seed weight in Brassica napus
Fine mapping and candidate gene analysis of the major QTL qSW-A03 for seed weight in Brassica napus Open
Seed weight is a determining factor for improving rapeseed productivity. In the present study, a high-density genetic map was constructed via genome resequencing in an RIL population derived from a cross of two rapeseed varieties, ZS11 and…
View article: Transcriptomic profiling of backfat and muscle in Lijiang pigs with divergent body size across growth stages
Transcriptomic profiling of backfat and muscle in Lijiang pigs with divergent body size across growth stages Open
View article: Prevalence of molecular markers of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum isolates from West Africa during 2012–2022
Prevalence of molecular markers of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum isolates from West Africa during 2012–2022 Open
Sulfadoxine-pyrimethamine (SP) is a key drug recommended by the World Health Organization for the chemoprevention of malaria. However, the strategy is affected by the parasite resistance to SP. This study evaluated Plasmodium falciparum di…
View article: Clinical analysis of bleeding and thrombotic events in haematological-oncology patients with severe thrombocytopenia and a high risk of thrombosis
Clinical analysis of bleeding and thrombotic events in haematological-oncology patients with severe thrombocytopenia and a high risk of thrombosis Open
For haematological neoplasm patients with a high risk of venous thromboembolism (VTE), severe thrombocytopenia and high CCI scores, risk prevention and control of bleeding take precedence over thrombosis prophylaxis. Prophylactic anticoagu…
View article: AMD-SD: An Optical Coherence Tomography Image Dataset for wet AMD Lesions Segmentation
AMD-SD: An Optical Coherence Tomography Image Dataset for wet AMD Lesions Segmentation Open
Wet Age-related Macular Degeneration (wet AMD) is a common ophthalmic disease that significantly impacts patients' vision. Optical coherence tomography (OCT) examination has been widely utilized for diagnosing, treating, and monitoring wet…
View article: Case report: TP53 c.848G>A germline mutation as a possible screening target at initial diagnosis for acute lymphoblastic leukemia
Case report: TP53 c.848G>A germline mutation as a possible screening target at initial diagnosis for acute lymphoblastic leukemia Open
This suspected Li-Fraumeni syndrome case report with a likely pathogenic heterozygous TP53 variant expands the cancer genetic spectrum. Screening her family members for mutations facilitates identifying the optimal relative donor and avoid…
View article: Prevalence of Molecular Markers of Sulfadoxine-pyrimethamine Resistance in Plasmodium falciparum Isolates from West Africa during 2012–2022
Prevalence of Molecular Markers of Sulfadoxine-pyrimethamine Resistance in Plasmodium falciparum Isolates from West Africa during 2012–2022 Open
Sulfadoxine-pyrimethamine (SP) is a key drug recommended by the World Health Organization for the chemoprevention of malaria. However, the strategy is affected by the parasite resistance to SP. This study evaluated Plasmodium falciparum di…
View article: Lead-adsorbing ionogel-based encapsulation for impact-resistant, stable, and lead-safe perovskite modules
Lead-adsorbing ionogel-based encapsulation for impact-resistant, stable, and lead-safe perovskite modules Open
Despite the high-efficiency and low-cost prospect for perovskite solar cells, great concerns of lead toxicity and instability remain for this technology. Here, we report an encapsulation strategy for perovskite modules based on lead-adsorb…
View article: Recent Advances in and Application of Fluorescent Microspheres for Multiple Nucleic Acid Detection
Recent Advances in and Application of Fluorescent Microspheres for Multiple Nucleic Acid Detection Open
Traditional single nucleic acid assays can only detect one target while multiple nucleic acid assays can detect multiple targets simultaneously, providing comprehensive and accurate information. Fluorescent microspheres in multiplexed nucl…