Yunyun Su
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View article: Petal stomata of Hemerocallis citrina Baroni are sensitive to abscisic acid
Petal stomata of Hemerocallis citrina Baroni are sensitive to abscisic acid Open
In response to drought stress, abscisic acid (ABA) plays a crucial role in regulating stomatal closure in both leaf and floral tissues. Studies on stomatal regulation have primarily focused on the leaves of vascular plants, but stomatal re…
View article: Early identification of sarcopenia in patients with diabetes mellitus combined with osteoporosis: development and validation of a gender-specific nomogram
Early identification of sarcopenia in patients with diabetes mellitus combined with osteoporosis: development and validation of a gender-specific nomogram Open
Objective The aim of this study was to develop a predictive model to screen for sarcopenia in patients with type 2 diabetes mellitus (T2DM) combined with osteoporosis, with a view to identifying and intervening early in those at high risk …
View article: Zinc Alleviates Diabetic Muscle Atrophy via Modulation of the SIRT1/FoxO1 Autophagy Pathway Through GPR39
Zinc Alleviates Diabetic Muscle Atrophy via Modulation of the SIRT1/FoxO1 Autophagy Pathway Through GPR39 Open
Background Muscle atrophy is a severe complication of diabetes, with autophagy playing a critical role in its progression. Zinc has been shown to alleviate hyperglycaemia and several diabetes‐related complications, but its direct role in m…
View article: Association of Red Blood Cell Distribution Width With Carotid–Femoral Pulse Wave Velocity in a Southern Chinese Population
Association of Red Blood Cell Distribution Width With Carotid–Femoral Pulse Wave Velocity in a Southern Chinese Population Open
Red blood cell distribution width (RDW) has recently been recognized as a novel biomarker associated with various cardiovascular conditions. This study aims to investigate the relationship between RDW and carotid–femoral pulse wave velocit…
View article: Integrative omics analysis identifies biomarkers of septic cardiomyopathy
Integrative omics analysis identifies biomarkers of septic cardiomyopathy Open
Septic Cardiomyopathy (SCM) is a syndrome of acute cardiac dysfunction in septic patients, unrelated to cardiac ischemia. Multiomics studies including transcriptomics and proteomics have provided new insights into the mechanisms of SCM. In…
View article: Causal role of immune cells in muscle atrophy: mendelian randomization study
Causal role of immune cells in muscle atrophy: mendelian randomization study Open
Immune system and inflammation had a great influence on the progression of muscle atrophy. However, the causal relationship with specific immune cell traits remained uncertain. The aim of this study was to elucidate the genetic influences …
View article: Dentatacid A: An Unprecedented 2, 3-Seco-arbor-2, 3-dioic Triterpenoid from the Invasive Plant Euphorbia dentata, with Cytotoxicity Effect on Colon Cancer
Dentatacid A: An Unprecedented 2, 3-Seco-arbor-2, 3-dioic Triterpenoid from the Invasive Plant Euphorbia dentata, with Cytotoxicity Effect on Colon Cancer Open
Euphorbia dentata Michx. is an invasive plant species in China, known for its toxicity and potential to reduce crop yields, posing numerous threats. To gain a deeper understanding of this invasive plant, phytochemical methods were employed…
View article: Response of selenium pools to drought stress by regulating physio‑biochemical attributes and anatomical changes in Gentiana macrophylla
Response of selenium pools to drought stress by regulating physio‑biochemical attributes and anatomical changes in Gentiana macrophylla Open
Selenium (Se), as a vital stress ameliorant, possesses a beneficial effect on mediating detrimental effects of environmental threats. However, the mechanisms of Se in mitigating the deleterious effects of drought are still poorly understoo…
View article: Data from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop
Data from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop Open
Cancer stem cells (CSC) are thought to be responsible for tumor initiation and tumor regeneration after chemotherapy. Previously, we showed that chemotherapy of non–small cell lung cancer (NSCLC) cells lines can select for outgrowth of hig…
View article: Data from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop
Data from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop Open
Cancer stem cells (CSC) are thought to be responsible for tumor initiation and tumor regeneration after chemotherapy. Previously, we showed that chemotherapy of non–small cell lung cancer (NSCLC) cells lines can select for outgrowth of hig…
View article: Supplementary Figure Legends 1-2 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop
Supplementary Figure Legends 1-2 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop Open
Supplementary Figure Legends 1-2 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop
View article: Supplementary Figure Legends 1-2 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop
Supplementary Figure Legends 1-2 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop Open
Supplementary Figure Legends 1-2 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop
View article: Supplementary Figure 2 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop
Supplementary Figure 2 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop Open
Supplementary Figure 2 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop
View article: Data from Biological Significance of Prolactin in Gynecologic Cancers
Data from Biological Significance of Prolactin in Gynecologic Cancers Open
There is increasing evidence that prolactin (PRL), a hormone/cytokine, plays a role in breast, prostate, and colorectal cancers via local production or accumulation. Elevated levels of serum PRL in ovarian and endometrial cancers have been…
View article: Supplementary Figure 1 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop
Supplementary Figure 1 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop Open
Supplementary Figure 1 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop
View article: Supplementary Figure 2 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop
Supplementary Figure 2 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop Open
Supplementary Figure 2 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop
View article: Supplementary Table 1 from Biological Significance of Prolactin in Gynecologic Cancers
Supplementary Table 1 from Biological Significance of Prolactin in Gynecologic Cancers Open
Supplementary Table 1 from Biological Significance of Prolactin in Gynecologic Cancers
View article: Supplementary Figure 1 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop
Supplementary Figure 1 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop Open
Supplementary Figure 1 from Elimination of Human Lung Cancer Stem Cells through Targeting of the Stem Cell Factor–c-kit Autocrine Signaling Loop
View article: Supplementary Table 1 from Biological Significance of Prolactin in Gynecologic Cancers
Supplementary Table 1 from Biological Significance of Prolactin in Gynecologic Cancers Open
Supplementary Table 1 from Biological Significance of Prolactin in Gynecologic Cancers
View article: Data from Biological Significance of Prolactin in Gynecologic Cancers
Data from Biological Significance of Prolactin in Gynecologic Cancers Open
There is increasing evidence that prolactin (PRL), a hormone/cytokine, plays a role in breast, prostate, and colorectal cancers via local production or accumulation. Elevated levels of serum PRL in ovarian and endometrial cancers have been…
View article: E4 engages uPAR and enolase-1 and activates urokinase to exert antifibrotic effects
E4 engages uPAR and enolase-1 and activates urokinase to exert antifibrotic effects Open
Fibroproliferative disorders such as systemic sclerosis (SSc) have no effective therapies and result in significant morbidity and mortality. We recently demonstrated that the C-terminal domain of endostatin, known as E4, prevented and reve…
View article: A Pilot Study for the Feasibility of Exome-Sequencing in Circulating Tumor Cells Versus Single Metastatic Biopsies in Breast Cancer
A Pilot Study for the Feasibility of Exome-Sequencing in Circulating Tumor Cells Versus Single Metastatic Biopsies in Breast Cancer Open
The comparison of the landscape of somatic alterations in circulating tumor cells (CTCs) versus metastases is challenging. Here, we comprehensively characterized the somatic landscape in bulk (amplified and non-amplified), spike-in breast …
View article: Acetylcholine ameliorates the adverse effects of cadmium stress through mediating growth, photosynthetic activity and subcellular distribution of cadmium in tobacco (Nicotiana benthamiana)
Acetylcholine ameliorates the adverse effects of cadmium stress through mediating growth, photosynthetic activity and subcellular distribution of cadmium in tobacco (Nicotiana benthamiana) Open
Acetylcholine (ACh), a well-known major neurotransmitter, plays a potential role in response to abiotic stresses. However, the mechanism of ACh-mediated cadmium (Cd) toxicity in tobacco seedlings is largely uncharacterized. In this study, …
View article: Improved Drought Tolerance by AMF Inoculation in Maize (Zea mays) Involves Physiological and Biochemical Implications
Improved Drought Tolerance by AMF Inoculation in Maize (Zea mays) Involves Physiological and Biochemical Implications Open
The role of arbuscular mycorrhizal fungus (AMF, Glomus versiforme) in amelioration of drought-induced effects on growth and physio-biochemical attributes in maize (Zea mays L.) was studied. Maize plants were exposed to two drought regimes,…
View article: Insulin‐like growth factor binding protein‐4 exerts antifibrotic activity by reducing levels of connective tissue growth factor and the C‐X‐C chemokine receptor 4
Insulin‐like growth factor binding protein‐4 exerts antifibrotic activity by reducing levels of connective tissue growth factor and the C‐X‐C chemokine receptor 4 Open
The insulin‐like growth factor (IGF) system plays an important role in variety cellular biological functions; we previously reported levels of IGF binding proteins (IGFBP)‐3 and ‐5 are increased in dermal and pulmonary fibrosis associated …
View article: IGFBP-5 Promotes Fibrosis Independently of Its Translocation to the Nucleus and Its Interaction with Nucleolin and IGF
IGFBP-5 Promotes Fibrosis Independently of Its Translocation to the Nucleus and Its Interaction with Nucleolin and IGF Open
IGFBP-5 transport to the nucleus requires an intact NLS and nucleolin. However, nuclear translocation is not necessary for IGFBP-5 fibrotic activity; neither is IGF binding. Our data provide further insights into the role of cellular compa…