Yuqin Tang
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View article: Association Between Vitamin D and Microvascular Changes in Early Diabetic Retinopathy in Patients with Type 2 Diabetes
Association Between Vitamin D and Microvascular Changes in Early Diabetic Retinopathy in Patients with Type 2 Diabetes Open
Individuals with T2DM and vitamin D deficiency were highly recommended to undergo regular ophthalmic screenings to monitor retinal health.
View article: Biomarkers and immunotherapy in endometrial cancer: mechanisms and clinical applications
Biomarkers and immunotherapy in endometrial cancer: mechanisms and clinical applications Open
Advanced endometrial cancer (EC) poses significant therapeutic challenges due to molecular heterogeneity and immune evasion. Immune checkpoint inhibitors (ICIs) show promise, particularly in mismatch repair-deficient (MMRd) and POLE-mutate…
View article: In Vitro Polyploidy Induction of Longshan Lilium lancifolium from Regenerated Shoots and Morphological and Molecular Characterization
In Vitro Polyploidy Induction of Longshan Lilium lancifolium from Regenerated Shoots and Morphological and Molecular Characterization Open
Longshan Lilium lancifolium is a well-known medicinal and edible lily and has been registered as a geographical indicator in China. Polyploidization confers many advantages in lily production; however, characteristics of Longshan L. lancif…
View article: Exploring supply and demand imbalance of community-based older adult care: an observational study in Chongqing, China
Exploring supply and demand imbalance of community-based older adult care: an observational study in Chongqing, China Open
Objective Using an urban area in southwest China as a case study, this research investigates and analyzes the supply and demand of community-based older adult care services to provide a basis for optimizing the older adult care service sys…
View article: Yijing Decoction improves premature ovarian failure in rats by activating VEGF/VEGFR-2/FAK pathway
Yijing Decoction improves premature ovarian failure in rats by activating VEGF/VEGFR-2/FAK pathway Open
Not applicable.
View article: Identification of diagnostic genes and drug prediction in metabolic syndrome-associated rheumatoid arthritis by integrated bioinformatics analysis, machine learning, and molecular docking
Identification of diagnostic genes and drug prediction in metabolic syndrome-associated rheumatoid arthritis by integrated bioinformatics analysis, machine learning, and molecular docking Open
Background Interactions between the immune and metabolic systems may play a crucial role in the pathogenesis of metabolic syndrome-associated rheumatoid arthritis (MetS-RA). The purpose of this study was to discover candidate biomarkers fo…
View article: Exploring hot topics and evolutionary paths in the Diagnosis-Related Groups (DRGs) field: a comparative study using LDA modeling
Exploring hot topics and evolutionary paths in the Diagnosis-Related Groups (DRGs) field: a comparative study using LDA modeling Open
View article: Tumor immunological phenotype-derived gene classification predicts prognosis, treatment response, and drug candidates in ovarian cancer
Tumor immunological phenotype-derived gene classification predicts prognosis, treatment response, and drug candidates in ovarian cancer Open
View article: Integrative analysis of circadian clock with prognostic and immunological biomarker identification in ovarian cancer
Integrative analysis of circadian clock with prognostic and immunological biomarker identification in ovarian cancer Open
Objective: To identify circadian clock (CC)-related key genes with clinical significance, providing potential biomarkers and novel insights into the CC of ovarian cancer (OC). Methods: Based on the RNA-seq profiles of OC patients in The Ca…
View article: Deciphering the immune heterogeneity dominated by natural killer cells with prognostic and therapeutic implications in hepatocellular carcinoma
Deciphering the immune heterogeneity dominated by natural killer cells with prognostic and therapeutic implications in hepatocellular carcinoma Open
Belonging to type 1 innate lymphoid cells (ILC1), natural killer (NK) cells play an important role not only in fighting microbial infections but also in anti-tumor response. Hepatocellular carcinoma (HCC) represents an inflammation-related…
View article: Exploring the mechanism of Cassiae semen in regulating lipid metabolism through network pharmacology and experimental validation
Exploring the mechanism of Cassiae semen in regulating lipid metabolism through network pharmacology and experimental validation Open
Background: Multiple studies have assessed the role of Cassiae semen (CS) in regulating lipid metabolism. However, the mechanism of action of CS on non-alcoholic fatty liver disease (NAFLD) has seen rare scrutiny. Objective: The objective …
View article: Characterization of cellular senescence patterns predicts the prognosis and therapeutic response of hepatocellular carcinoma
Characterization of cellular senescence patterns predicts the prognosis and therapeutic response of hepatocellular carcinoma Open
Background: Hepatocellular carcinoma (HCC) is a prevalent malignancy with a high mortality rate. Cellular senescence, an irreversible state of cell cycle arrest, plays a paradoxical role in cancer progression. Here, we aimed to identify He…
View article: Hallmark-guided subtypes of hepatocellular carcinoma for the identification of immune-related gene classifiers in the prediction of prognosis, treatment efficacy, and drug candidates
Hallmark-guided subtypes of hepatocellular carcinoma for the identification of immune-related gene classifiers in the prediction of prognosis, treatment efficacy, and drug candidates Open
Hepatocellular carcinoma (HCC), accounting for ~90% of all primary liver cancer, is a prevalent malignancy worldwide. The intratumor heterogeneity of its causative etiology, histology, molecular landscape, and immune phenotype makes it dif…
View article: Hallmark guided identification and characterization of a novel immune-relevant signature for prognostication of recurrence in stage I–III lung adenocarcinoma
Hallmark guided identification and characterization of a novel immune-relevant signature for prognostication of recurrence in stage I–III lung adenocarcinoma Open
View article: Transcriptome-Wide Characterization of Seed Aging in Rice: Identification of Specific Long-Lived mRNAs for Seed Longevity
Transcriptome-Wide Characterization of Seed Aging in Rice: Identification of Specific Long-Lived mRNAs for Seed Longevity Open
Various long-lived mRNAs are stored in seeds, some of which are required for the initial phase of germination and are critical to seed longevity. However, the seed-specific long-lived mRNAs involved in seed longevity remain poorly understo…
View article: Identification of a Tumor Immunological Phenotype-Related Gene Signature for Predicting Prognosis, Immunotherapy Efficacy, and Drug Candidates in Hepatocellular Carcinoma
Identification of a Tumor Immunological Phenotype-Related Gene Signature for Predicting Prognosis, Immunotherapy Efficacy, and Drug Candidates in Hepatocellular Carcinoma Open
Hepatocellular carcinoma (HCC) is the predominant subtype of primary liver cancer and represents a highly heterogeneous disease, making it hard to predict the prognosis and therapy efficacy. Here, we established a novel tumor immunological…
View article: N-Acetyldopamine Dimer Attenuates DSS-Induced Ulcerative Colitis by Suppressing NF-κB and MAPK Pathways
N-Acetyldopamine Dimer Attenuates DSS-Induced Ulcerative Colitis by Suppressing NF-κB and MAPK Pathways Open
Ulcerative Colitis (UC) is a major form of chronic inflammatory bowel disease of the colonic mucosa and exhibits progressive morbidity. There is still a substantial need of small molecules with greater efficacy and safety for UC treatment.…
View article: Action Mechanism Underlying Improvement Effect of Fuzi Lizhong Decoction on Nonalcoholic Fatty Liver Disease: A Study Based on Network Pharmacology and Molecular Docking
Action Mechanism Underlying Improvement Effect of Fuzi Lizhong Decoction on Nonalcoholic Fatty Liver Disease: A Study Based on Network Pharmacology and Molecular Docking Open
Objective. This study aimed to decipher the bioactive compounds and potential mechanism of traditional Chinese medicine (TCM) formula Fuzi Lizhong Decoction (FLD) for nonalcoholic fatty liver disease (NAFLD) treatment via an integrative ne…
View article: Exploring the Mechanism of Danggui Shaoyao San in the treatment of Non-alcoholic Fatty Liver Disease: A Study based on Network Pharmacology and Molecular Docking
Exploring the Mechanism of Danggui Shaoyao San in the treatment of Non-alcoholic Fatty Liver Disease: A Study based on Network Pharmacology and Molecular Docking Open
Background Non-alcoholic fatty liver disease (NAFLD), the most prevalent chronic liver disease in the world, has yet to identify a particular medicine for treatment. Danggui Shaoyao San (DSS), a traditional Chinese medicine formula, has st…
View article: Taohong Siwu Decoction exerts anticancer effects on breast cancer via regulating MYC, BIRC5, EGF and PIK3R1 revealed by HTS2 technology
Taohong Siwu Decoction exerts anticancer effects on breast cancer via regulating MYC, BIRC5, EGF and PIK3R1 revealed by HTS2 technology Open
Taohong Siwu Decoction (TSD), a classical gynecological prescription that was firstly reported 600 years ago, has been widely used in the adjuvant treatment of breast cancer (BRCA) in China. However, the mechanism of action of TSD in treat…
View article: Integrative analysis identifies key mRNA biomarkers for diagnosis, prognosis, and therapeutic targets of HCV-associated hepatocellular carcinoma
Integrative analysis identifies key mRNA biomarkers for diagnosis, prognosis, and therapeutic targets of HCV-associated hepatocellular carcinoma Open
Hepatitis C virus-associated HCC (HCV-HCC) is a prevalent malignancy worldwide and the molecular mechanisms are still elusive. Here, we screened 240 differentially expressed genes (DEGs) of HCV-HCC from Gene expression omnibus (GEO) and th…
View article: Mining TCGA Data for Key Biomarkers Related to Immune Microenvironment in Endometrial cancer by Immune Score and Weighted Correlation Network Analysis
Mining TCGA Data for Key Biomarkers Related to Immune Microenvironment in Endometrial cancer by Immune Score and Weighted Correlation Network Analysis Open
Background: Endometrial cancer (EC) is one of the most lethal gynecological cancers around the world. The aim of this study is to identify the potential immune microenvironment-related biomarkers associated with the prognosis for EC. Metho…
View article: Mining TCGA Data for Key Biomarkers Related to Immune Microenvironment in Endometrial Carcinoma by Immune Score and Weighted Correlation Network Analysis
Mining TCGA Data for Key Biomarkers Related to Immune Microenvironment in Endometrial Carcinoma by Immune Score and Weighted Correlation Network Analysis Open
Background: Endometrial cancer (EC) is one of the most lethal gynecological cancer in women. It is imperative to identify the potential immune microenvironment-related biomarkers associated with the prognosis for EC. Methods: RNA-seq data …
View article: Identification of Potential Hub Genes Related to Diagnosis and Prognosis of Hepatitis B Virus‐Related Hepatocellular Carcinoma via Integrated Bioinformatics Analysis
Identification of Potential Hub Genes Related to Diagnosis and Prognosis of Hepatitis B Virus‐Related Hepatocellular Carcinoma via Integrated Bioinformatics Analysis Open
Hepatocellular carcinoma (HCC) is a common malignant cancer with poor survival outcomes, and hepatitis B virus (HBV) infection is most likely to contribute to HCC. But the molecular mechanism remains obscure. Our study intended to identify…
View article: Effects of Land Cover Pattern Along Urban-Rural Gradient on Bird Diversity in Wetlands
Effects of Land Cover Pattern Along Urban-Rural Gradient on Bird Diversity in Wetlands Open
Wetlands play an important role in the feeding, breeding, and lives of birds. However, available habitats for bird species are changing due to intensifying human activity, especially in the context of China’s mass urbanization. Urban spraw…
View article: The Effect of SIN1 and Microtubules on Insulin Induced PKC ζ Activation
The Effect of SIN1 and Microtubules on Insulin Induced PKC ζ Activation Open
BACKGROUND Protein kinase C zeta (PKC ζ) plays an important role in insulin induced glycometabolism and insulin receptor (IR) associated signaling pathways. The full activation of PKC ζ depends on its translocation from cytosol to membrane…
View article: Results of a pilot study of patient-to-patient education strategy on self-management among glycemic uncontrolled patients with diabetes
Results of a pilot study of patient-to-patient education strategy on self-management among glycemic uncontrolled patients with diabetes Open
This preliminary evidence suggests that PTP education strategy is acceptable for facilitating the outcome of glycemic control. Patient sense of complications may work on A1c reduction.