Yuqing Xia
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View article: Risk factors for breast cancer: an umbrella review of observational cohort studies and causal relationship analysis
Risk factors for breast cancer: an umbrella review of observational cohort studies and causal relationship analysis Open
Objective To conduct an umbrella review of prospective meta-analyses and perform a causal relationship analysis to evaluate causal effects. Methods PubMed, Web of Science, Embase, and manual reference list searches were used from database …
View article: Comparison of plasma sterilizer and conventional laminar flow room in allogeneic hematopoietic stem cell transplant recipients
Comparison of plasma sterilizer and conventional laminar flow room in allogeneic hematopoietic stem cell transplant recipients Open
Patients receiving allogeneic hematopoietic stem cell transplantation (allo-HSCT) are typically placed in a laminar air flow room until hematopoietic reconstitution occurs. In this study, we compared the differences in clinical outcomes be…
View article: Whole-Transcriptome Analysis Reveals Potential CeRNA Regulatory Mechanism in Takifugu rubripes against Cryptocaryon irritans Infection
Whole-Transcriptome Analysis Reveals Potential CeRNA Regulatory Mechanism in Takifugu rubripes against Cryptocaryon irritans Infection Open
Cryptocaryon irritans (C. irritans) is a proto-ciliate parasite that infects marine fishes, including the cultured species Takifugu rubripes (T. rubripes), causing disease and potential mortality. In host organisms, infection by parasites …
View article: Investigation of copper-induced intestinal damage and proteome alterations in Takifugu rubripes: Potential health risks and environmental toxicology detection
Investigation of copper-induced intestinal damage and proteome alterations in Takifugu rubripes: Potential health risks and environmental toxicology detection Open
Copper is one of the predominant water pollutants. Excessive exposure to copper can cause harm to animal health, affecting the central nervous system and causing blood abnormalities. Cuproptosis is a novel form of cell death that differs f…
View article: Comprehensive identification of plant peroxisome targeting signal type 1 tripeptides
Comprehensive identification of plant peroxisome targeting signal type 1 tripeptides Open
Peroxisomes are universal eukaryotic organelles hosting various metabolic pathways, with particularly diverse metabolic roles in plants (Pan et al., 2020). Severe peroxisomal dysfunction can lead to fatal genetic disorders in humans and em…
View article: Copper exposure causes alteration in the intestinal microbiota and metabolites in Takifugu rubripes
Copper exposure causes alteration in the intestinal microbiota and metabolites in Takifugu rubripes Open
Copper is an environmental pollutant, and copper in aquatic environments mainly comes from soil and water. It enters the environment through atmospheric deposition, sewage discharge, and industrial production, and enters aquatic organisms,…
View article: Dual roles of CCDC102A in governing centrosome duplication and cohesion
Dual roles of CCDC102A in governing centrosome duplication and cohesion Open
In animal cells, the dysregulation of centrosome duplication and cohesion maintenance leads to abnormal spindle assembly and chromosomal instability, contributing to developmental disorders and tumorigenesis. However, the molecular mechani…
View article: Chemotherapy combined with bevacizumab for small cell lung cancer with brain metastases: A case report
Chemotherapy combined with bevacizumab for small cell lung cancer with brain metastases: A case report Open
BACKGROUND Small cell lung cancer (SCLC) is a common and aggressive subtype of lung cancer. It is characterized by rapid growth and a high mortality rate. Approximately 10% of patients with SCLC present with brain metastases at the time of…
View article: Combination of RCA and DNAzyme for Dual-Signal Isothermal Amplification of Exosome RNA
Combination of RCA and DNAzyme for Dual-Signal Isothermal Amplification of Exosome RNA Open
The RNA contained in exosomes plays a crucial role in information transfer between cells in various life activities. The accurate detection of low-abundance exosome RNA (exRNA) is of great significance for cell function studies and the ear…
View article: Visual genetic typing of glioma using proximity‐anchored in situ spectral coding amplification
Visual genetic typing of glioma using proximity‐anchored in situ spectral coding amplification Open
Gliomas are histologically and genetically heterogeneous tumors. However, classical histopathological typing often ignores the high heterogeneity of tumors and thus cannot meet the requirements of precise pathological diagnosis. Here, prox…
View article: Concomitant analyses of intratumoral microbiota and genomic features reveal distinct racial differences in breast cancer
Concomitant analyses of intratumoral microbiota and genomic features reveal distinct racial differences in breast cancer Open
Racial disparities are most accentuated among Black women as their lifetime risk of breast cancer incidence is lower than white and Asian women but their breast cancer related mortality is the highest among all races. Black women are more …
View article: Effects of feeding methods on ecological soil wastewater infiltration systems for sewage treatment
Effects of feeding methods on ecological soil wastewater infiltration systems for sewage treatment Open
Intermittent feeding method and continuous feeding method were adopted in two experimental form ecological soil wastewater infiltration systems (ESWISs), respectively. The results showed that COD, NH 4 + and TN removal efficiencies were en…
View article: Genome-wide integrated analysis reveals functions of lncRNA-miRNA-mRNA interactions in Atlantic salmon challenged by Aeromonas salmonicida
Genome-wide integrated analysis reveals functions of lncRNA-miRNA-mRNA interactions in Atlantic salmon challenged by Aeromonas salmonicida Open
Aeromonas salmonicida (A. salmonicida) is a pathogenic bacterium that causes serious problems in the global Atlantic salmon aquaculture industry. In this study, we comprehensively analyzed the profiles of lncRNAs, miRNAs and mRNAs in gills…
View article: Identification and expression analysis of a fibrinogen alpha chain-like gene in Atlantic salmon (Salmo salar)
Identification and expression analysis of a fibrinogen alpha chain-like gene in Atlantic salmon (Salmo salar) Open
Fibrinogen is a protein involved in platelet aggregation that is essential for the coagulation of blood, and it plays a role in the fish immune system. In this study, a fibrinogen alpha chain-like gene of the Atlantic salmon (Salmo salar) …
View article: α-/γ-Taxilin are required for centriolar subdistal appendage assembly and microtubule organization
α-/γ-Taxilin are required for centriolar subdistal appendage assembly and microtubule organization Open
The centrosome, composed of a pair of centrioles (mother and daughter centrioles) and pericentriolar material, is mainly responsible for microtubule nucleation and anchorage in animal cells. The subdistal appendage (SDA) is a centriolar st…
View article: Non-Mechanism Model for Superheater Pollution Diagnosis of Waste Incinerator Based on BP Neural Network
Non-Mechanism Model for Superheater Pollution Diagnosis of Waste Incinerator Based on BP Neural Network Open
Dust accumulation of boiler heating surface is one of the common problems in power plants, which will affect the unit’s economic and safe operation in serious cases. In this paper, the factors that affect the ash deposition in the superhea…
View article: Salinomycin exerts anti‐colorectal cancer activity by targeting the β‐catenin/T‐cell factor complex
Salinomycin exerts anti‐colorectal cancer activity by targeting the β‐catenin/T‐cell factor complex Open
Background and Purpose Salinomycin is a well‐known inhibitor of human cancer stem cells ( CSCs ). However, the molecular mechanism(s) by which salinomycin targets colorectal CSCs is poorly understood. Here, we have investigated underlying …
View article: <p>Longdaysin inhibits Wnt/&beta;-catenin signaling and exhibits antitumor activity against breast cancer</p>
Longdaysin inhibits Wnt/β-catenin signaling and exhibits antitumor activity against breast cancer Open
Longdaysin is a novel inhibitor of the Wnt/β-catenin signaling pathway. It exerts antitumor effect through blocking CK1δ/ε-dependent Wnt signaling.
View article: Tumor promoter TPA activates Wnt/β-catenin signaling in a casein kinase 1-dependent manner
Tumor promoter TPA activates Wnt/β-catenin signaling in a casein kinase 1-dependent manner Open
Significance The phorbol ester 12- O -tetra-decanoylphorbol-13-acetate (TPA) is a well-known tumor promoter in two-stage mouse skin carcinogenesis, but the exact mechanism by which TPA promotes tumorigenesis remains elusive. This study dis…
View article: miR-290 contributes to the low abundance of cyclin D1 protein in mouse embryonic stem cells
miR-290 contributes to the low abundance of cyclin D1 protein in mouse embryonic stem cells Open
Mouse miR-290 cluster miRNAs are expressed specifically in early embryos and embryonic germ cells. These miRNAs play critical roles in the maintenance of pluripotency and self-renewal. Here, we showed that Cyclin D1 is a direct target gene…
View article: Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68
Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68 Open
In animal cells, the centrosome is the main microtubule-organizing centre where microtubules are nucleated and anchored. The centriole subdistal appendages (SDAs) are the key structures that anchor microtubules in interphase cells, but the…