Yuri Ogasawara
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View article: Impact of ursodeoxycholic acid treatment on Fontan-associated liver disease
Impact of ursodeoxycholic acid treatment on Fontan-associated liver disease Open
Background Fontan-associated liver disease (FALD) is a type of progressive liver fibrosis that occurs following Fontan surgery and can be complicated by hepatocellular carcinoma (HCC). Established treatments for FALD are lacking. Therefore…
View article: Serum level of full-length connective tissue growth factor reflects liver fibrosis stage in patients with Fontan-associated liver disease
Serum level of full-length connective tissue growth factor reflects liver fibrosis stage in patients with Fontan-associated liver disease Open
Background Chronic liver disease leads to liver fibrosis, and an accurate diagnosis of the fibrosis stage is crucial for medical management. Connective tissue growth factor (CTGF) is produced by endothelial cells and platelets and plays a …
View article: Analysis of genetic factors associated with fatty liver disease‐related hepatocellular carcinoma
Analysis of genetic factors associated with fatty liver disease‐related hepatocellular carcinoma Open
Aim Single‐nucleotide polymorphisms (SNPs) in PNPLA3 and hydroxysteroid 17‐beta dehydrogenase 13 ( HSD17B13 ) genes are associated with fatty liver disease (FLD) progression and carcinogenesis. In the present study, we evaluated the charac…
View article: Outcomes of fatty liver disease with and without metabolic comorbidities and risk factors for mortality
Outcomes of fatty liver disease with and without metabolic comorbidities and risk factors for mortality Open
Background and Aim As the clinical course of metabolic‐associated fatty liver disease (MAFLD) is unclear, we compared the clinical courses of MAFLD and non‐alcoholic FLD (NAFLD). Methods Asian FLD patients ( n = 987) from 1991 to 2021 (bio…
View article: Outcomes of fatty liver disease with and without metabolic comorbidities and risk factors for mortality
Outcomes of fatty liver disease with and without metabolic comorbidities and risk factors for mortality Open
Aims Patients with fatty liver disease (FLD) frequently have metabolic risk factors; however, the clinical course of metabolic-associated FLD (MAFLD) in Asians is unclear. We compared the clinical courses of MAFLD and nonalcoholic FLD (NAF…
View article: Risk and protective factors of acute kidney injury in decompensated cirrhotic patients with ascites on tolvaptan
Risk and protective factors of acute kidney injury in decompensated cirrhotic patients with ascites on tolvaptan Open
Background and Aim Acute kidney injury (AKI) is a life‐threatening complication of liver cirrhosis. Here, we evaluated the risk factors and characteristics of AKI in cirrhosis. Patients/Methods This was a single‐center retrospective study.…
View article: Long‐term outcome of Wilson's disease complicated by liver disease
Long‐term outcome of Wilson's disease complicated by liver disease Open
Background and Aim Wilson's disease (WD) is a rare inherited disease that causes systemic copper accumulation. This study examined the long‐term course of WD patients with liver disease. Methods The 12 patients (9 female patients) enrolled…
View article: Long-term Follow-up of a Patient with Portal Hypertension and Hepatic Failure Due to Hepatic Hydatid Disease
Long-term Follow-up of a Patient with Portal Hypertension and Hepatic Failure Due to Hepatic Hydatid Disease Open
We observed liver failure with a presumed etiology of echinococcosis in an 89-year-old woman. Our patient had been born and then resided on Rebun Island until she was 12 years old. At 46 years old, she had been referred to our hospital due…