Yushuang Luo
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View article: Novel Biomarkers as Non-Invasive Diagnostic Tools in IgA Nephropathy: A Comparative Study with Lupus Nephritis and Membranous Nephropathy
Novel Biomarkers as Non-Invasive Diagnostic Tools in IgA Nephropathy: A Comparative Study with Lupus Nephritis and Membranous Nephropathy Open
VLA-4 and VEGFD emerge as robust, non-invasive biomarkers for IgAN diagnosis and may play significant roles in the pathogenesis of IgAN.
View article: Crocin promotes ferroptosis in gastric cancer via the Nrf2/GGTLC2 pathway
Crocin promotes ferroptosis in gastric cancer via the Nrf2/GGTLC2 pathway Open
Introduction: Gastric cancer (GC) is characterized by high incidence and poor survival rates. Crocin, a natural carotenoid from saffron, exhibits antioxidant, anti-inflammatory, and anti-tumor properties. Ferroptosis, an iron-dependent cel…
View article: Efficacy of immune checkpoint inhibitors combined with bevacizumab in MSS/pMMR advanced colorectal cancer after first-line treatment failure
Efficacy of immune checkpoint inhibitors combined with bevacizumab in MSS/pMMR advanced colorectal cancer after first-line treatment failure Open
Objective To investigate the effects of a PD-1 inhibitor combined with a bevacizumab monoclonal antibody on tumor immune cells in patients with first-line treatment failure in MSS/pMMR advanced colorectal cancer. Methods Control group cons…
View article: The Impact of PD-1 Inhibitor Combined with Bevacizumab on Tumor Immune Cells in MSS/pMMR Advanced Colorectal Cancer Patients with Failed First-Line Treatment
The Impact of PD-1 Inhibitor Combined with Bevacizumab on Tumor Immune Cells in MSS/pMMR Advanced Colorectal Cancer Patients with Failed First-Line Treatment Open
Objective: To investigate the effects of PD-1 inhibitor combined with bevacizumab monoclonal antibody on tumor immune cells in patients with first-line treatment failure in MSS/pMMR advanced colorectal cancer. Methods: A total of 40 patien…
View article: Streptomyces chenzhouensis sp. nov., an endophytic actinobacterium from the root tissue of Cathaya argyrophylla
Streptomyces chenzhouensis sp. nov., an endophytic actinobacterium from the root tissue of Cathaya argyrophylla Open
An endophytic actinobacterium, designated strain HUAS 5 T , was isolated from the root tissue of Cathaya argyrophylla collected in Chenzhou city of Hunan Province, PR China. This strain produced grey aerial mycelium that differentiated int…
View article: Ginsenoside Rh2 Suppresses Metastasis and Growth of Colon Cancer via miR-491
Ginsenoside Rh2 Suppresses Metastasis and Growth of Colon Cancer via miR-491 Open
Ginsenoside Rh2 is considered as a new direction for future cancer treatment because of its excellent anticancer effect. However, due to its low bioavailability, it cannot exert its significant anticancer effect when applied directly to th…
View article: Efficacy and Safety of Apatinib for Elderly Patients with Advanced or Metastatic Gastric Cancer After Failure of at Least First-Line Chemotherapy: A Multi-Center, Single-Arm, Phase II Study
Efficacy and Safety of Apatinib for Elderly Patients with Advanced or Metastatic Gastric Cancer After Failure of at Least First-Line Chemotherapy: A Multi-Center, Single-Arm, Phase II Study Open
These data suggest that apatinib is effective and relatively tolerable for elderly patients with unresectable advanced or metastatic gastric cancer who have received at least first-line chemotherapy.
View article: Inhibitory Effect of Crocin Against Gastric Carcinoma via Regulating TPM4 Gene
Inhibitory Effect of Crocin Against Gastric Carcinoma via Regulating TPM4 Gene Open
Crocin could inhibit the gastric cancer cells AGS cells proliferation by regulating TPM4 gene expression, and TPM4 may be a promising therapeutic target for GC treatment.
View article: Pathogenesis and anti-proliferation mechanisms of Crocin in human gastric carcinoma cells.
Pathogenesis and anti-proliferation mechanisms of Crocin in human gastric carcinoma cells. Open
Gastric cancer is the fourth most common cause of cancer death globally and the second most common in Asia. Many studies suggest that Crocin has the potential for gastric cancer antineoplastic combined chemotherapy protocols. Here we inves…
View article: Glibenclamide-Induced Autophagy Inhibits Its Insulin Secretion-Improving Function in <i>β</i> Cells
Glibenclamide-Induced Autophagy Inhibits Its Insulin Secretion-Improving Function in <i>β</i> Cells Open
Diabetes is a metabolic disease, partly due to hypoinsulinism, which affects ∼8% of the world’s adult population. Glibenclamide is known to promote insulin secretion by targeting β cells. Autophagy as a self-protective mechanism of cells h…
View article: Effect of Ammonia Exposure on the Non-Specific Immunity of Fresh Water Pearl Mussel Hyriopsis cumingii
Effect of Ammonia Exposure on the Non-Specific Immunity of Fresh Water Pearl Mussel Hyriopsis cumingii Open
Ammonia-N, the principal end-product of protein catabolism, is an important environmental toxic factor in ponds. Elevated environmental ammonia-N is very toxic to aquatic animals and has a deleterious effect on their immune system. However…
View article: miR-17–92 cluster is connected with disease progression and oxaliplatin/capecitabine chemotherapy efficacy in advanced gastric cancer patients
miR-17–92 cluster is connected with disease progression and oxaliplatin/capecitabine chemotherapy efficacy in advanced gastric cancer patients Open
This study aimed to determine the role of plasma miR-17-92 cluster level in predicting chemoresistance in patients with gastric cancer (GC) undergoing oxaliplatin/capecitabine (XELOX) chemotherapy.Patients recently diagnosed with advanced …