Explanipedia

Efficacy and safety of endoscopic glue injection in acute peptic ulcer bleeding Open

XingSi Qi, Jia Li, S B Wang, Junbo Zhang, Hao Chen , et al. · 2025

Background: Optimal management of peptic ulcer bleeding remains a clinical challenge. Objectives: To evaluate the efficacy and safety of endoscopic glue injection (EGI) for acute peptic ulcer bleeding. Design: Single-center retrospective s…

Diagnosis model for gastric submucosal tumor based on multiple decision trees comprising endoscopic and endoscopic ultrasonography features Open

Shen Su, Shun-Yao Wu, Yun-He Tang, Lin-Lin Ren, Fan Yin , et al. · 2025

This decision tree-based hierarchical model can potentially assist in the preoperative diagnosis of SEL and guide clinical decision-making for the individualized treatment of SEL patients.

A case report of Castleman disease variant of POEMS syndrome presenting with prominent polyserositis and renal impairment Open

Congcong Min, Ailing Liu, Yushuang Xu, Yanan Yu, Yonghong Xu , et al. · 2025

Background POEMS syndrome is a rare hematologic disorder related to plasma cell dyscrasia. The Castleman disease variant of POEMS syndrome is extremely rare and often misdiagnosed. In this study, we aim to present a noteworthy case of POEM…

The risk factors of lymph node metastasis in early colorectal cancer: a predictive nomogram and risk assessment Open

Jiahui Xu, Fan Yin, Linlin Ren, Yushuang Xu, Congcong Min , et al. · 2024

Clinical experience sharing on gastric microneuroendocrine tumors: A case report Open

You-Jun Wang, Da-Ming Fan, Yushuang Xu, Qi Zhao, Zhen-Fang Li · 2024

BACKGROUND The majority of gastric neuroendocrine tumors (G-NENs) are present in various lesions under endoscopy, and they can be polypoid uplifts, submucosal tumors or papules, erosions, and ulcers. The lesions are mostly confined to the …

Lower haemoglobin-to-red blood cell distribution width ratio is independently associated with frailty in community-dwelling older adults: a cross-sectional study Open

Mengpei Zhu, Chao Wei, Xiongjun Yang, Yumei Huang, Yushuang Xu , et al. · 2023

Objectives The importance of blood cell markers in frailty has been studied. However, research on haemoglobin-to-red blood cell distribution width ratio (HRR) and frailty in older persons is still limited. We investigated the association b…

Ruptured small pancreaticoduodenal artery aneurysm-clinical features similar to pancreatitis: A case report Open

Ya Nan Yu, Yushuang Xu, Pei Nie, Cong Cong Min, Xue Li Ding , et al. · 2023

Background: Pancreaticoduodenal artery aneurysm (PDAA) is rare and has high rupture risks. PDAA rupture has a wide range of clinical symptoms, including abdominal pain, nausea, syncope, and hemorrhagic shock, which is difficult to differen…

Prognostic Implication of a Cuproptosis-Related miRNA Signature in Hepatocellular Carcinoma Open

Ze Jin, Mengmeng Wang, Yajun Meng, Di Chen, Yushuang Xu , et al. · 2022

Background. Hepatocellular carcinoma (HCC) is one of the most frequently diagnosed malignancies globally, accounting for the third cause of cancer mortality. Cuproptosis, a copper-induced cell death, was recently reported in Science. The p…

Leveraging Existing 16SrRNA Microbial Data to Define a Composite Biomarker for Autism Spectrum Disorder Open

Yushuang Xu, Yihua Wang, JinShuang Xu, Yu Song, Bingqiang Liu , et al. · 2022

This study provides an updated analysis to characterize the gut microbiota in ASD using 16SrRNA gene high-throughput sequencing data from 10 publicly available studies. Our analysis suggests an association between the fecal microbiota and …

Identification of VCAM1 as a Novel Biomarker in the Immune Microenvironment of Gastric Cancer by Comprehensive Bioinformatics Analysis Open

Xin Jiang, Di Chen, Mengmeng Wang, Yushuang Xu, Meng-jun Qiu , et al. · 2022

Background and Purpose Gastric cancer (GC) is a common malignant tumor of the digestive tract worldwide and has high morbidity and mortality. The tumor immune microenvironment (TIME), especially the immune cell infiltration, plays an impor…

A Novel Angiogenesis-Related Prognostic Signature Associated with the Hepatocellular Carcinoma Immune Microenvironment and Survival Outcome Open

Xin Jiang, Yushuang Xu, Di Chen, Mengmeng Wang, Meng-jun Qiu , et al. · 2022

Xin Jiang, Yushuang Xu, Di Chen, Mengmeng Wang, Mengjun Qiu, Lina Xiong, Li Zhang, Honglu Yu, Zhifan Xiong Department of Gastroenterology, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Peopl…

Identification and Validation of the lncRNA BACE1-AS as Immune-Related Influencing Factor in Tumorigenesis following Pan-Carcinoma Analysis Open

Mengmeng Wang, Di Chen, Yushuang Xu, Meng-jun Qiu, Xin Jiang , et al. · 2021

Background. The lncRNA BACE1-AS was identified as a plasma molecular marker in the early diagnosis of Alzheimer’s disease, but its role in tumors remains poorly defined. Methods. The expression patterns, genomic mutation, and prognostic si…

Non-Coding RNAs in Gastric Cancer: From Malignant Hallmarks to Clinical Applications Open

Di Chen, Ping Shuai, Yushuang Xu, Mengmeng Wang, Xin Jiang , et al. · 2021

Gastric cancer (GC) is one of the most lethal malignancies worldwide. However, the molecular mechanisms underlying gastric carcinogenesis remain largely unknown. Over the past decades, advances in RNA-sequencing techniques have greatly fac…

A Novel Autophagy-Related lncRNA Prognostic Signature Associated with Immune Microenvironment and Survival Outcomes of Gastric Cancer Patients Open

Di Chen, Mengmeng Wang, Yushuang Xu, Xin Jiang, Lina Xiong , et al. · 2021

The 5 autophagy-related lncRNA signature has significant clinical implications in prognosis prediction of GC. Meanwhile, our study elucidates the critical role of the autophagy-related lncRNA signature in the TIME of GC.

Altered Fecal Microbiota Composition in Older Adults With Frailty Open

Yushuang Xu, Yihua Wang, HeWei Li, Yong Dai, Di Chen , et al. · 2021

Objective Frailty is a common geriatric syndrome that is diagnosed and staged based mainly on symptoms. We aimed to evaluate frailty-related alterations of the intestinal permeability and profile fecal microbiota of healthy and frail older…

The Roles of the Gut Microbiota and Chronic Low-Grade Inflammation in Older Adults With Frailty Open

Yushuang Xu, Xiangjie Liu, Xiaoxia Liu, Di Chen, Mengmeng Wang , et al. · 2021

Frailty is a major public issue that affects the physical health and quality of life of older adults, especially as the population ages. Chronic low-grade inflammation has been speculated to accelerate the aging process as well as the deve…

CSF1R is a Prognostic Biomarker and Correlated with Immune Cell Infiltration in the Gastric Cancer Microenvironment Open

Di Chen, Lina Xiong, Li Zhang, Honglu Yu, Yushuang Xu , et al. · 2021

In summary, CSF1R might take part in the modulation of immune-active status in the GC microenvironment and could be a promising biomarker for GC therapy and prognosis.

Diagnostic methods and drug therapies in patients with ischemic colitis Open

Yushuang Xu, Lina Xiong, YaNan Li, Xin Jiang, Zhifan Xiong · 2020

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