Yusuke Onozato
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View article: Early Diagnosis of Streptococcal Toxic Shock Syndrome With Abdominal Computed Tomography: A Case Report
Early Diagnosis of Streptococcal Toxic Shock Syndrome With Abdominal Computed Tomography: A Case Report Open
Streptococcal toxic shock syndrome (STSS) is a rapidly progressive and highly lethal infection caused by group A streptococcus, in which early diagnosis remains challenging due to nonspecific initial symptoms. We report a case of a 37-year…
View article: Prevalence and Distribution of Gastric Endoscopy Findings in Non-eosinophilic Esophagitis Eosinophilic Gastrointestinal Diseases: Influence of Atrophic Gastritis
Prevalence and Distribution of Gastric Endoscopy Findings in Non-eosinophilic Esophagitis Eosinophilic Gastrointestinal Diseases: Influence of Atrophic Gastritis Open
Objective The impact of Helicobacter pylori infection on gastric endoscopic findings in non-eosinophilic esophagitis eosinophilic gastrointestinal diseases (non-EoE EGIDs) remains unclear. This study investigated the influence of H. pylori…
View article: Risk factors and pattern of metastatic recurrence after endoscopic resection with additional treatment for esophageal cancer
Risk factors and pattern of metastatic recurrence after endoscopic resection with additional treatment for esophageal cancer Open
Summary Although esophageal cancers invading the muscularis mucosa (pT1a-MM) or submucosa (pT1b-SM) after endoscopic resection (ER) are associated with a risk of lymph node metastasis, details of metastatic recurrence after additional trea…
View article: Young Patient with X-linked Agammaglobulinemia Presents with Advanced Gastric Cancer and Extensive Atrophic Gastritis
Young Patient with X-linked Agammaglobulinemia Presents with Advanced Gastric Cancer and Extensive Atrophic Gastritis Open
X-linked agammaglobulinemia (XLA) is associated with an increased risk of gastrointestinal cancers including gastric cancer (GC). We herein report the case of a 30-year-old male patient with XLA who developed GC and extensive atrophic gast…
View article: Long-term course of untreated asymptomatic esophageal eosinophilia and minimally symptomatic eosinophilic esophagitis
Long-term course of untreated asymptomatic esophageal eosinophilia and minimally symptomatic eosinophilic esophagitis Open
Background and study aims The long-term course of untreated asymptomatic esophageal eosinophilia (aEE) and minimally symptomatic eosinophilic esophagitis (mEoE) are not well understood. This study aimed to clarify this course. Patients and…
View article: Exocrine Pancreatic Insufficiency Possibly Related to Atypical Chronic Graft-versus-Host Disease
Exocrine Pancreatic Insufficiency Possibly Related to Atypical Chronic Graft-versus-Host Disease Open
We report the case of a 66-year-old woman who presented with diarrhea and weight loss approximately 14 months after unrelated allogeneic bone marrow transplantation for acute myeloid leukemia. Her early post-transplant course was notable f…
View article: Pyrexia And Liver Injury After A Second SARS-CoV-2 Vaccination : Macrophage Activation Manifested In Liver
Pyrexia And Liver Injury After A Second SARS-CoV-2 Vaccination : Macrophage Activation Manifested In Liver Open
Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-Co V-2) has contributed to control of the coronavirus disease 2019 (COVID-19). On the other side, vaccination of SARS-CoV-2 could trigger autoimmune or inflammatory …
View article: Supplementary Material for: Exocrine pancreatic insufficiency possibly related to atypical chronic graft-versus-host disease
Supplementary Material for: Exocrine pancreatic insufficiency possibly related to atypical chronic graft-versus-host disease Open
We report the case of a 66-year-old woman who presented with diarrhea and weight loss approximately fourteen months after unrelated allogeneic bone marrow transplantation for acute myeloid leukemia. Her early post-transplant course was not…
View article: Endoscopic Diagnosis of Eosinophilic Esophagitis: Basics and Recent Advances
Endoscopic Diagnosis of Eosinophilic Esophagitis: Basics and Recent Advances Open
Eosinophilic esophagitis (EoE) is a chronic, immune-mediated inflammatory disease, characterized by esophageal dysfunction and intense eosinophil infiltration localized in the esophagus. In recent decades, EoE has become a growing concern …
View article: Linked color imaging improves the diagnostic accuracy of eosinophilic esophagitis
Linked color imaging improves the diagnostic accuracy of eosinophilic esophagitis Open
Objectives To assess the usefulness of linked color imaging (LCI), a recently developed image‐enhanced endoscopy technique, in the endoscopic diagnosis of eosinophilic esophagitis (EoE). Methods Thirty white light images (WLIs) and 30 WLI+…
View article: An Unusual Small Bowel Phytobezoar Successfully Resolved by Double-balloon Enteroscopy
An Unusual Small Bowel Phytobezoar Successfully Resolved by Double-balloon Enteroscopy Open
We herein report a very unusual case of small bowel obstruction caused by phytobezoar in a 69-year-old woman who consumed a large amount of bracken. The patient presented with nausea and vomiting. Computed tomography revealed an air-filled…
View article: Prognostic impact of lingual lymph node metastasis in patients with squamous cell carcinoma of the tongue: a retrospective study
Prognostic impact of lingual lymph node metastasis in patients with squamous cell carcinoma of the tongue: a retrospective study Open
Squamous cell carcinoma (SCC) of the tongue rarely metastasizes to the lingual lymph nodes (LLNs), which are inconstant nodes and often situated outside the areas of basic tongue tumor surgery. The current study evaluated the clinicopathol…
View article: Small-bowel Capsule Endoscopic Features in Patients with Eosinophilic Gastroenteritis: Three Case Reports
Small-bowel Capsule Endoscopic Features in Patients with Eosinophilic Gastroenteritis: Three Case Reports Open
Eosinophilic gastroenteritis (EGE) is an uncommon disease characterized by eosinophilic infiltration of the gastrointestinal tract in the absence of secondary causes and presents with a variety of gastrointestinal manifestations. Important…
View article: Characteristics of the gut microbiome profile in obese patients with colorectal cancer
Characteristics of the gut microbiome profile in obese patients with colorectal cancer Open
Background and Aim Obesity affects the gut microbiome, which in turn increases the risk for colorectal cancer. Several studies have shown the mechanisms by which some bacteria may influence the development of colorectal cancer; however, gu…
View article: Fluctuation in radioresponse of HeLa cells during the cell cycle evaluated based on micronucleus frequency
Fluctuation in radioresponse of HeLa cells during the cell cycle evaluated based on micronucleus frequency Open
In this study, we examined the fluctuation in radioresponse of HeLa cells during the cell cycle. For this purpose, we used HeLa cells expressing two types of fluorescent ubiquitination-based cell cycle indicators (Fucci), HeLa-Fucci (CA)2 …
View article: Clinical Features of Esophageal Eosinophilia According to Endoscopic Phenotypes
Clinical Features of Esophageal Eosinophilia According to Endoscopic Phenotypes Open
Objective Esophageal eosinophilia (EE), a histological hallmark of eosinophilic esophagitis, is classified into two endoscopic phenotypes: localized and diffuse EE. Our aim was to determine the prevalence of EE localized in the lower esoph…
View article: Cronkhite-Canada Syndrome Associated with Gastric Outlet Obstruction and Membranous Nephropathy: A Case Report and Review of the Literature
Cronkhite-Canada Syndrome Associated with Gastric Outlet Obstruction and Membranous Nephropathy: A Case Report and Review of the Literature Open
A 47-year-old man presented with dysgeusia, anorexia, and diarrhea. An endoscopic evaluation showed widespread gastrointestinal nodular inflammation and polyps. The pathological findings were consistent with Cronkhite-Canada Syndrome (CCS)…
View article: A case of neuroendocrine carcinoma arising in the floor of the mouth
A case of neuroendocrine carcinoma arising in the floor of the mouth Open
Neuroendocrine carcinomas occur mainly in the lung and digestive tract and rarely arise in the oral cavity.We report a case of neuroendocrine carcinoma arising in the floor of the mouth.A 77-year-old man was referred to our department beca…
View article: Radiosensitivity of quiescent and proliferating cells grown as multicellular tumor spheroids
Radiosensitivity of quiescent and proliferating cells grown as multicellular tumor spheroids Open
The multicellular spheroid model partly mimics tumor microenvironments in vivo and has been reported in plenty of studies regarding radiosensitivity. However, clear isolation of quiescent and proliferating cells in live conditions has been…
View article: A case of tongue cancer accompanied by essential thrombocythemia
A case of tongue cancer accompanied by essential thrombocythemia Open
We report a case of tongue cancer accompanied by essential thrombocythemia. A 66-year-old-man was referred to our hospital in November 2014 after he was given a diagnosis of squamous cell carcinoma of the right side of the tongue. He had b…