Yutaka Toyomasu
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View article: Efficacy and Safety of Hypofractionated Radiation Therapy Combined With Immunotherapy for Hepatocellular Carcinoma With Vp4 Portal Vein Tumor Thrombosis
Efficacy and Safety of Hypofractionated Radiation Therapy Combined With Immunotherapy for Hepatocellular Carcinoma With Vp4 Portal Vein Tumor Thrombosis Open
Background Hepatocellular carcinoma (HCC) with Vp4 portal vein tumor thrombosis (PVTT) has an extremely poor prognosis, and evidence for effective systemic therapy is limited. Preclinical studies suggest that hypofractionated radiation the…
View article: Patients with a Short Distance Between the Prostate and the Rectum Are Appropriate Candidates for Hydrogel Spacer Placement to Prevent Short-Term Rectal Hemorrhage After External-Beam Radiotherapy for Prostate Cancer
Patients with a Short Distance Between the Prostate and the Rectum Are Appropriate Candidates for Hydrogel Spacer Placement to Prevent Short-Term Rectal Hemorrhage After External-Beam Radiotherapy for Prostate Cancer Open
Radiation therapy, including external-beam radiation therapy (EBRT) and brachytherapy, is curative for localized prostate cancer. Hydrogel spacer (HS) placement between the rectum and prostate is popular for reducing radiation-related comp…
View article: Superficial Temporal Artery‐Based <scp>ReMAP</scp> : A Case Report Series in Head and Neck Cancer Intra‐Arterial Chemotherapy
Superficial Temporal Artery‐Based <span>ReMAP</span> : A Case Report Series in Head and Neck Cancer Intra‐Arterial Chemotherapy Open
Background Intra‐arterial chemotherapy (IAC) can be highly effective for advanced head and neck cancers but often necessitates complex procedures and prolonged hospitalization. Herein, we demonstrate the utility of the repeatable microcath…
View article: Cardiac CT reveals high prevalence of coronary artery disease in esophageal cancer eligible for radiotherapy
Cardiac CT reveals high prevalence of coronary artery disease in esophageal cancer eligible for radiotherapy Open
Background: Assessment of cardiac disease before cancer therapy is crucial, as advancements in cancer treatment have led to prolonged survival and an increase in cardiovascular complications. Specifically, esophageal cancer and heart disea…
View article: Survival Outcomes in Egfr Mutant Versus Wild-Type Locally Advanced Non-Small Cell Lung Cancer Treated with Chemoradiotherapy: A Systematic Review and Meta-Analysis Based on Reconstructed Individual Patient Data
Survival Outcomes in Egfr Mutant Versus Wild-Type Locally Advanced Non-Small Cell Lung Cancer Treated with Chemoradiotherapy: A Systematic Review and Meta-Analysis Based on Reconstructed Individual Patient Data Open
View article: Expression of Tenascin-C Is Upregulated in the Early Stages of Radiation Pneumonitis/Fibrosis in a Novel Mouse Model
Expression of Tenascin-C Is Upregulated in the Early Stages of Radiation Pneumonitis/Fibrosis in a Novel Mouse Model Open
The lung is a major dose-limiting organ for radiation therapy (RT) for cancer in the thoracic region, and the clarification of radiation-induced lung damage (RILD) is important. However, there have been few reports containing a detailed co…
View article: Prognostic Role of Interim F-18 Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography During Chemoradiation Therapy in Patients with Hypopharyngeal Squamous Cell Carcinoma
Prognostic Role of Interim F-18 Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography During Chemoradiation Therapy in Patients with Hypopharyngeal Squamous Cell Carcinoma Open
View article: Initial Experience of Intra-Arterial Chemotherapy Using a Novel External Carotid Arterial Sheath System Combined with Radiotherapy and Systemic Chemotherapy for Locally Advanced Tongue Cancer
Initial Experience of Intra-Arterial Chemotherapy Using a Novel External Carotid Arterial Sheath System Combined with Radiotherapy and Systemic Chemotherapy for Locally Advanced Tongue Cancer Open
We retrospectively evaluated the safety and effectiveness of an external carotid arterial sheath (ECAS) for intra-arterial chemotherapy (IACT) for locally advanced tongue cancer. Thirty-one patients with the Union for International Cancer …
View article: Tenascin C in <scp>radiation‐induced</scp> lung damage: Pathological expression and serum level elevation
Tenascin C in <span>radiation‐induced</span> lung damage: Pathological expression and serum level elevation Open
Radiation‐induced lung damage (RILD) is a critical problem in lung cancer radiotherapy, and it is difficult to predict its severity. Although no biomarkers for RILD have been established, tenascin C (TNC) is an extracellular matrix glycopr…
View article: Intra‐arterial chemoradiotherapy for locally advanced buccal mucosal cancer in an elderly patient with multiple comorbidities: A case report
Intra‐arterial chemoradiotherapy for locally advanced buccal mucosal cancer in an elderly patient with multiple comorbidities: A case report Open
Background The management of locally advanced oral cavity squamous cell carcinoma (LA‐OCScc) in elderly patients with multiple comorbidities is difficult. Case We report the case of an elderly patient with buccal mucosal squamous cell carc…
View article: Endobronchial brachytherapy combined with surgical procedure for synchronous multiple primary lung cancer: A case report
Endobronchial brachytherapy combined with surgical procedure for synchronous multiple primary lung cancer: A case report Open
The management of synchronous multiple primary lung cancer is a challenge. In this report, we describe our experience in a patient with three synchronous multiple cancers. The first lesion was completely surgically removed, the second lesi…
View article: Sinonasal Undifferentiated Carcinoma
Sinonasal Undifferentiated Carcinoma Open
鼻副鼻腔未分化癌は希少がんであるため,治療法がまだ標準化されていない。今回我々が経験した鼻副鼻腔未分化癌4例の診療経過を報告する。全症例とも進行期(Stage IVAまたはIVB)であった。症例1:39歳女性。複視で発症した海綿静脈洞と視交叉への浸潤を伴う蝶形骨洞癌で,化学放射線療法と広範囲定位放射線治療を施行した結果,腫瘍が消失して視力が回復し,現在11年間無病生存中である。症例2:65歳女性。鼻腔癌で内視鏡下経鼻的前頭蓋底腫瘍切除・再建術と術後化学放射線療法を施行し,2…
View article: Reduced Left Ventricular Myocardial Blood Flow After Radiation Therapy For Thoracic Esophagus Cancer: A Study Using Stress Dynamic Perfusion CT
Reduced Left Ventricular Myocardial Blood Flow After Radiation Therapy For Thoracic Esophagus Cancer: A Study Using Stress Dynamic Perfusion CT Open
View article: Intra-arterial chemoradiotherapy including internal carotid arterial infusion for advanced maxillary sinus cancer with orbital invasion
Intra-arterial chemoradiotherapy including internal carotid arterial infusion for advanced maxillary sinus cancer with orbital invasion Open
眼窩内に上顎洞癌が浸潤した3症例に視力温存を目的とした内頸動脈からの動注治療を加えた化学放射線治療を施行した。2例には全身化学療法として2回のTPF（taxotere，cisplatin，5FU）を施行した。動注療法は浅側頭動脈に挿入したECAS （External Carotid Arterial Sheath）からマイクロカテーテルを目的動脈に挿入。動注薬剤はチオ硫酸ナトリウム併用下に週1回CDDP（35mg/m2〜50mg/m2）を投与。放射線治療はIMRT（inte…
View article: The Clinical Outcomes of Hemicortical Extracorporeal Irradiated Autologous Bone Graft After Tumor Resection of Bone and Soft Tissue Sarcoma
The Clinical Outcomes of Hemicortical Extracorporeal Irradiated Autologous Bone Graft After Tumor Resection of Bone and Soft Tissue Sarcoma Open
Early full weight-bearing may be achieved in patients undergoing hemicortical resection and reconstruction using extracorporeal irradiated autologous bone graft.
View article: Prognostic Role of Interim 18f-FDG-PET/CT during Chemoradiotherapy in Hypopharyngeal Carcinoma
Prognostic Role of Interim 18f-FDG-PET/CT during Chemoradiotherapy in Hypopharyngeal Carcinoma Open
View article: Thrombotic Microangiopathy Associated with Carbon Ion Radiotherapy and Chemotherapy for Osteosarcoma: a Case Report
Thrombotic Microangiopathy Associated with Carbon Ion Radiotherapy and Chemotherapy for Osteosarcoma: a Case Report Open
View article: EP-1178 Prognostic role of FDG-PET/CT during radiotherapy in patients with hypopharyngeal carcinoma
EP-1178 Prognostic role of FDG-PET/CT during radiotherapy in patients with hypopharyngeal carcinoma Open
View article: Long-term follow-up of intensive chemotherapy followed by reduced-dose and reduced-field irradiation for intracranial germ cell tumor
Long-term follow-up of intensive chemotherapy followed by reduced-dose and reduced-field irradiation for intracranial germ cell tumor Open
OBJECTIVE The authors analyzed the efficacy of intensive chemotherapy followed by reduced-dose and reduced-field irradiation for intracranial germ cell tumors (GCTs) and evaluated the long-term late effects caused by chemoradiotherapy (CRT…
View article: Outcomes of Patients With Sinonasal Squamous Cell Carcinoma Treated With Particle Therapy Using Protons or Carbon Ions
Outcomes of Patients With Sinonasal Squamous Cell Carcinoma Treated With Particle Therapy Using Protons or Carbon Ions Open
To our knowledge, this is the largest retrospective study of sinonasal squamous cell carcinoma treated with particle therapy alone. The efficacy of PT and CIT indicated that particle therapy can serve an important role in treating this dis…
View article: Preliminary Treatment Results of Radiation Therapy With Intra-Arterial Infusion Chemotherapy for Oral Cancer
Preliminary Treatment Results of Radiation Therapy With Intra-Arterial Infusion Chemotherapy for Oral Cancer Open
View article: Endobronchial brachytherapy with curative intent: the impact of reference points setting according to the bronchial diameter
Endobronchial brachytherapy with curative intent: the impact of reference points setting according to the bronchial diameter Open
Endobronchial brachytherapy (EBB) is an effective treatment for endobronchial tumors. However, bronchial toxicity caused by over-irradiation remains problematic. To decrease bronchial toxicity, we developed a source-centralizing applicator…
View article: PO-0713: Diffusion-weighted MRI for predicting prognosis after radiotherapy in stage IIIB cervical cancer
PO-0713: Diffusion-weighted MRI for predicting prognosis after radiotherapy in stage IIIB cervical cancer Open
View article: PO-0936: Dose effects of draining rectal gas in imageguided brachytherapy for gynecological cancer
PO-0936: Dose effects of draining rectal gas in imageguided brachytherapy for gynecological cancer Open
View article: The impact of epidermal growth factor receptor mutations on patterns of disease recurrence after chemoradiotherapy for locally advanced non–small cell lung cancer: a literature review and pooled analysis
The impact of epidermal growth factor receptor mutations on patterns of disease recurrence after chemoradiotherapy for locally advanced non–small cell lung cancer: a literature review and pooled analysis Open
The purpose of this review was to evaluate the impact of epidermal growth factor receptor (EGFR) mutation status on disease recurrence in patients treated with chemoradiotherapy (CRT) for locally advanced non–small cell lung cancer (NSCLC)…
View article: The impact of emphysema on dosimetric parameters for stereotactic body radiotherapy of the lung
The impact of emphysema on dosimetric parameters for stereotactic body radiotherapy of the lung Open
The purpose of this study was to evaluate the impact of emphysematous changes in lung on dosimetric parameters in stereotactic body radiation therapy (SBRT) for lung tumor. A total of 72 treatment plans were reviewed, and dosimetric factor…
View article: Multimodality Treatment for Patients with Node-Positive Prostate Cancer: the Role of Radiation Therapy
Multimodality Treatment for Patients with Node-Positive Prostate Cancer: the Role of Radiation Therapy Open
Prostate cancer is the secondary most frequently diagnosed cancer in the world. Although numerous prospective randomized trial have been conducted to guide the management of patients with localized or locally advanced prostate cancer, few …
View article: Roles of Valproic Acid in Improving Radiation Therapy for Glioblastoma: a Review of Literature Focusing on Clinical Evidence
Roles of Valproic Acid in Improving Radiation Therapy for Glioblastoma: a Review of Literature Focusing on Clinical Evidence Open
Glioblastoma (GBM) is the most common and aggressive type of primary brain neoplasm. The current standard therapy for GBM consists of maximal surgical resection within safe limits, followed by radiation therapy (RT) and chemotherapy with t…
View article: Preliminary treatment results of proton beam therapy with chemoradiotherapy for stage I–III esophageal cancer
Preliminary treatment results of proton beam therapy with chemoradiotherapy for stage I–III esophageal cancer Open
The effect of proton beam therapy ( PBT ) on various cancers is controversial. We aimed to evaluate the efficacy and safety of PBT with alternating chemoradiotherapy ( ACRT ) for patients with stage I–III esophageal cancer. Two cycles of s…
View article: Treatment results of alternating chemoradiotherapy followed by proton beam therapy boost combined with intra-arterial infusion chemotherapy for stage III–IVB tongue cancer
Treatment results of alternating chemoradiotherapy followed by proton beam therapy boost combined with intra-arterial infusion chemotherapy for stage III–IVB tongue cancer Open