Yuting Su
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View article: The Hippo kinases MST1/2 integrate sterile and infectious signals to regulate macrophage cell death
The Hippo kinases MST1/2 integrate sterile and infectious signals to regulate macrophage cell death Open
Mammalian STE20-like kinases MST1 and MST2 are the conserved Hippo kinases known for their importance in organ development and tumor suppression. Notably, humans and mice lacking these kinases have increased susceptibility to infection, in…
View article: LAMC3 interference reduces drug resistance of carboplatin-resistant ovarian cancer cells
LAMC3 interference reduces drug resistance of carboplatin-resistant ovarian cancer cells Open
View article: Efficacy of cyclin-dependent kinases 4 and 6 inhibitors in the treatment of HR +/HER2 − advanced breast cancer: a meta-analysis
Efficacy of cyclin-dependent kinases 4 and 6 inhibitors in the treatment of HR +/HER2 − advanced breast cancer: a meta-analysis Open
CDK4/6i combined with ET improves disease control by decreasing progression and increasing stability, though it shows a lower PR rate than ET + chemotherapy in HR + /HER2 - advanced breast cancer. These findings underscore the need to bala…
View article: Cleavage of the Hippo kinases and programmed cell death in murine macrophages exposed to sterile stimuli and bacterial pathogens
Cleavage of the Hippo kinases and programmed cell death in murine macrophages exposed to sterile stimuli and bacterial pathogens Open
Mammalian STE20-like kinases MST1 and MST2 are the conserved Hippo kinases known for their importance in organ development and tumor suppression. Notably, humans and mice lacking these kinases have increased susceptibility to infection, in…
View article: The predictive value of peripheral blood monocytic myeloid-derived suppressor cells for survival and immunotherapy responses in tumor patients
The predictive value of peripheral blood monocytic myeloid-derived suppressor cells for survival and immunotherapy responses in tumor patients Open
View article: IncI2 plasmid transfer and changes of intestinal microbiota in mice under β-lactam antibiotic pressure
IncI2 plasmid transfer and changes of intestinal microbiota in mice under β-lactam antibiotic pressure Open
Background β-lactam antibiotics represent the most widely utilized class of antimicrobial agents in livestock and poultry breeding. However, the effects of β-lactam antibiotics on conjugation transfer of IncI2 plasmids and the homeostasis …
View article: Comparison of ST19 Salmonella Typhimurium and ST34 Salmonella I,4,[5],12:i:-: a trade-off between plasmid-mediated antibiotic resistance and virulence
Comparison of ST19 Salmonella Typhimurium and ST34 Salmonella I,4,[5],12:i:-: a trade-off between plasmid-mediated antibiotic resistance and virulence Open
View article: Predictive value of pretreatment peripheral blood N/CD4 and N/CD8 ratios for the efficacy of radiotherapy for esophageal cancer
Predictive value of pretreatment peripheral blood N/CD4 and N/CD8 ratios for the efficacy of radiotherapy for esophageal cancer Open
Background This study aimed to explore the predictive value of pretreatment peripheral blood immune cell subsets in analyzing the outcomes of patients who underwent radiation therapy for esophageal cancer at their first visit. Patients and…
View article: International Legal Framework for Cyber Attacks in Outer Space:The Issue of “Use of Force”
International Legal Framework for Cyber Attacks in Outer Space:The Issue of “Use of Force” Open
View article: Variation of Microorganisms and Water Quality, and Their Impacts on the Production of Penaeus vannamei in Small-Scale Greenhouse Ponds
Variation of Microorganisms and Water Quality, and Their Impacts on the Production of Penaeus vannamei in Small-Scale Greenhouse Ponds Open
To study the factors affecting Penaeus vannamei production in small-scale greenhouse ponds, four ponds in Jiangmen, Guangdong Province, China were selected. This study investigated the variation in the characteristics of bacterial communit…
View article: The negative off-response driven by M-cone and depolarizing bipolar cell in the rat electroretinogram
The negative off-response driven by M-cone and depolarizing bipolar cell in the rat electroretinogram Open
To elucidate the contributions of M-cone to the negative off-response of rat Electroretinogram (ERG) using specific drugs and spontaneous mutation rat models. The ON/OFF responses of ERG were evoked by long duration flash (200 ms) pre or p…
View article: Activation of the conserved Hippo kinases by inflammasome-triggered proteolytic cleavage controls programmed cell death in macrophages
Activation of the conserved Hippo kinases by inflammasome-triggered proteolytic cleavage controls programmed cell death in macrophages Open
The mammalian Hippo kinases, MST1 and MST2, regulate organ development and suppress tumor formation by balancing cell proliferation and death. In macrophages, inflammasomes detect molecular patterns from invading pathogens or damaged host …
View article: PC-YOLO11s: A Lightweight and Effective Feature Extraction Method for Small Target Image Detection
PC-YOLO11s: A Lightweight and Effective Feature Extraction Method for Small Target Image Detection Open
Compared with conventional targets, small objects often face challenges such as smaller size, lower resolution, weaker contrast, and more background interference, making their detection more difficult. To address this issue, this paper pro…
View article: The dual role of SLC7A11 in tumor drug resistance: mechanisms, challenges, and therapeutic potential
The dual role of SLC7A11 in tumor drug resistance: mechanisms, challenges, and therapeutic potential Open
Tumor drug resistance is a major factor in cancer treatment failure. SLC7A11 is characterized as a light-chain subunit antiporter of the Xc- system, responsible for exchanging extracellular cystine with intracellular glutamate. …
View article: Germination-Driven Dynamic Changes of Phenolic Compounds in Oats and the Underlying Mechanisms for Antioxidation Enhancement
Germination-Driven Dynamic Changes of Phenolic Compounds in Oats and the Underlying Mechanisms for Antioxidation Enhancement Open
View article: Cholinesterase Inhibitor Reveals Synergistic Potential for Neural Stem Cell-Based Therapy in the 5xFAD Mouse Model of Alzheimer’s Disease
Cholinesterase Inhibitor Reveals Synergistic Potential for Neural Stem Cell-Based Therapy in the 5xFAD Mouse Model of Alzheimer’s Disease Open
Combining ChEIs with NSC transplantation produces synergistic effects in AD treatment. This approach highlights the potential of integrating these therapies to develop more effective strategies for managing Alzheimer's disease.
View article: Evolution and maintenance of a large multidrug-resistant plasmid in a <i>Salmonella enterica</i> Typhimurium host under differing antibiotic selection pressures
Evolution and maintenance of a large multidrug-resistant plasmid in a <i>Salmonella enterica</i> Typhimurium host under differing antibiotic selection pressures Open
The dissemination of antibiotic resistance genes (ARGs) through plasmids is a major mechanism for the development of bacterial antimicrobial resistance. The adaptation and evolution mechanisms of multidrug-resistant (MDR) plasmids with the…
View article: Correction: PSMD9 promotes the malignant progression of hepatocellular carcinoma by interacting with c-Cbl to activate EGFR signaling and recycling
Correction: PSMD9 promotes the malignant progression of hepatocellular carcinoma by interacting with c-Cbl to activate EGFR signaling and recycling Open
View article: Upregulation of miRNA-450b-5p targets ACTB to affect drug resistance and prognosis of ovarian cancer via the PI3K/Akt signaling pathway
Upregulation of miRNA-450b-5p targets ACTB to affect drug resistance and prognosis of ovarian cancer via the PI3K/Akt signaling pathway Open
High expression of miRNA-450b-5p might affect drug resistance and prognosis in OC by targeting 13 co-expressed genes of ACTB directly through the PI3K/Akt signaling pathway. Thus, miR-450b-5p might provide a new therapeutic target for drug…
View article: Identification of genes predicting chemoresistance and short survival in ovarian cancer
Identification of genes predicting chemoresistance and short survival in ovarian cancer Open
The identified genes specifically the CASP2 might be potentially used as predictive marker, prognostic marker and therapeutic target in management of OC.
View article: Correction to: Low FHL1 expression indicates a good prognosis and drug sensitivity in ovarian cancer
Correction to: Low FHL1 expression indicates a good prognosis and drug sensitivity in ovarian cancer Open
View article: PSMD9 promotes the malignant progression of hepatocellular carcinoma by interacting with c-Cbl to activate EGFR signaling and recycling
PSMD9 promotes the malignant progression of hepatocellular carcinoma by interacting with c-Cbl to activate EGFR signaling and recycling Open
Background Mounting evidences shows that the ubiquitin‒proteasome pathway plays a pivotal role in tumor progression. The expression of 26S proteasome non-ATPase regulatory subunit 9 (PSMD9) is correlated with recurrence and radiotherapy re…
View article: The Hippo kinases control inflammatory Hippo signaling and restrict bacterial infection in phagocytes
The Hippo kinases control inflammatory Hippo signaling and restrict bacterial infection in phagocytes Open
The Hippo kinases MST1 and MST2 initiate a highly conserved signaling cascade called the Hippo pathway that limits organ size and tumor formation in animals. Intriguingly, pathogens hijack this host pathway during infection, but the role o…
View article: MarkPlugger: Generalizable Watermark Framework for Latent Diffusion Models without Retraining
MarkPlugger: Generalizable Watermark Framework for Latent Diffusion Models without Retraining Open
Today, the family of latent diffusion models (LDMs) has gained prominence for its high quality outputs and scalability. This has also raised security concerns on social media, as malicious users can create and disseminate harmful content. …
View article: Graph Disentangled Contrastive Learning with Personalized Transfer for Cross-Domain Recommendation
Graph Disentangled Contrastive Learning with Personalized Transfer for Cross-Domain Recommendation Open
Cross-Domain Recommendation (CDR) has been proven to effectively alleviate the data sparsity problem in Recommender System (RS). Recent CDR methods often disentangle user features into domain-invariant and domain-specific features for effi…
View article: Ether-linked phosphatidylethanolamine is a chemo-desensitizer of human carcinomas and epithelial ovarian cancer cells
Ether-linked phosphatidylethanolamine is a chemo-desensitizer of human carcinomas and epithelial ovarian cancer cells Open
Background Lipid reprogramming in carcinoma is reported to have a role in carcinogenesis, prognosis, and therapy response. Autonomous or nonautonomous resources may contribute to lipid reprogramming. Nonautonomous lipid resources contribut…
View article: Linoleate-pazopanib conjugation as active pharmacological ingredient to abolish hepatocellular carcinoma growth
Linoleate-pazopanib conjugation as active pharmacological ingredient to abolish hepatocellular carcinoma growth Open
Small molecule compounds targeting multiple kinases involved in neoangiogenesis have shown survival benefits in patients with unresectable hepatocellular carcinoma (HCC). Nonetheless, despite the beneficial effects of multikinase inhibitor…
View article: A High-Mixed Order Contrastive Transformer Network for Few-Shot Anomaly Detection
A High-Mixed Order Contrastive Transformer Network for Few-Shot Anomaly Detection Open
View article: Synergetic Effect of Non-Invasive Posttreatment Agents Enables High Efficiency and Stable All-Inorganic Sn-Pb Perovskite Solar Cells
Synergetic Effect of Non-Invasive Posttreatment Agents Enables High Efficiency and Stable All-Inorganic Sn-Pb Perovskite Solar Cells Open
View article: A New Kind of Naturally Occurring Mouse Model for Usher Syndrome Generated by Crossing with Cba/J Mice
A New Kind of Naturally Occurring Mouse Model for Usher Syndrome Generated by Crossing with Cba/J Mice Open