Explanipedia

Hepatocellular Carcinoma Confined to the Bile Duct without Hepatic Mass or Jaundice: A Case Report Open

Yuto Aoki, Masato Yoshioka, Yohei Kaneya, Kazuhiko Endo, Ryo Ga , et al. · 2025

This case highlights a rare presentation of HCC without a hepatic mass or jaundice, confined to the intrahepatic bile duct. Most patients present with obstructive jaundice. Only two other English-language cases have no prior history of pri…

Laparoscopic Resection of a Large Mucinous Cystic Neoplasm of the Liver: A Case Report Open

Yuto Aoki, Yukio Oshiro, Ryo Ga, Mampei Kawashima, Chikako Hasegawa , et al. · 2025

Mucinous cystic neoplasms of the liver (MCNs-L) are rare cystic tumors characterized by multilocular cysts lined with a mucin-producing epithelium and supported by ovarian-like stroma. These tumors account for <5% of all cystic liver lesio…

Diagnosis of necrotic and non‐necrotic small bowel strangulation: The importance of intestinal congestion Open

Takeshi Yamada, Yuto Aoki, Akihisa Matsuda, Yasuyuki Yokoyama, Goro Takahashi , et al. · 2024

Background Despite the prevalence of laparoscopic techniques in abdominal surgeries today, bowel obstruction remains a potentially serious complication. Small bowel strangulation (SBS), in particular, is a critical condition that can lead …

Evaluation of hepatic resection in adolescent and young adult patients with hepatocellular carcinoma Open

Junji Ueda, Yasuhiro Mamada, Nobuhiko Taniai, Masato Yoshioka, Akira Matsushita , et al. · 2024

Background In Japan, primary hepatocellular carcinoma (HCC) often develops against a background of chronic hepatitis, such as persistent hepatitis B virus (HBV) or hepatitis C virus (HCV) infection. Patients with HCC are commonly in their …

Current Status of Robotic Hepatobiliary and Pancreatic Surgery Open

Keisuke Minamimura, Yuto Aoki, Youhei Kaneya, Satoshi Matsumoto, Hiroki Arai , et al. · 2024

Laparoscopic surgery is performed worldwide and has clear economic and social benefits in terms of patient recovery time. It is used for most gastrointestinal surgical procedures, but laparoscopic surgery for more complex procedures in the…

Distribution of Splenic Arterial Flow and Segmental Spleen Volume for Partial Splenic Arterial Embolization Open

Junji Ueda, Yasuhiro Mamada, Nobuhiko Taniai, Masato Yoshioka, Akira Matsushita , et al. · 2023

The present findings on segmental spleen volume are useful for estimating infarction volume in cases of partial splenic arterial embolization.

Evaluation of splenic infarction ratio and platelet increase ratio after partial splenic artery embolization Open

Junji Ueda, Yasuhiro Mamada, Nobuhiko Taniai, Masato Yoshioka, Akira Matsushita , et al. · 2023

Objective The spleen is part of the lymphatic system and is one of the least understood organs of the human body. It is involved in the production of blood cells and helps filter the blood, remove old blood cells, and fight infection. Part…

Medical Treatment for Hepatocellular Carcinoma in Japan Open

Youichi Kawano, Yohei Kaneya, Yuto Aoki, Masato Yoshioka, Akira Matsushita , et al. · 2022

Liver cancer, including hepatocellular carcinoma (HCC), is the fifth most common cause of cancer deaths in Japan. The main treatment options for HCC are surgical resection, liver transplantation, radiofrequency ablation (RFA), transarteria…

Short-term Outcomes of Liver Resection in Patients With Hemodialysis Open

Shintaro Kanaka, Yuto Aoki, Masato Yoshioka, Youichi Kawano, Tetsuya Shimizu , et al. · 2021

Liver resections, at least segmentectomy or smaller, is acceptable in patients on hemodialysis. However, these patients may have a higher risk of postoperative infectious complications than other patients.

Three cases of follicular pancreatitis: association between radiological findings and pathological features Open

Ryota Kondo, Ryuichi Wada, Akira Matsushita, Yoshiharu Nakamura, Masato Yoshioka , et al. · 2020

Follicular pancreatitis (FP) is characterized by nodular mass composed of lymphoid hyperplasia and fibrosis. We here present radiological and pathological features of three cases of FP. The three patients were middle- or old-aged men, and …

Effectiveness of Laparoscopic Repeat Hepatectomy for Recurrent Liver Cancer Open

Masato Yoshioka, Nobuhiko Taniai, Youichi Kawano, Tetsuya Shimizu, Ryota Kondo , et al. · 2019

LapRH for recurrent liver cancer yielded satisfactory outcomes when compared with those of initial hepatectomy. Further studies are needed, however, to confirm the present results.

Laparoscopic Repeat Hepatectomy with Indocyanine Green Fluorescence Navigation: A Case Report Open

Masato Yoshioka, Nobuhiko Taniai, Youichi Kawano, Tetsuya Shimizu, Ryota Kondo , et al. · 2019

The indocyanine green (ICG) fluorescence method is reportedly useful for intraoperative visualization of hepatocellular carcinoma and metastatic liver cancer. Herein, we report the use of an ICG fluorescence navigation system for laparosco…

Drug properties of fosravuconazole L-lysine ethanolate (NAILIN<sup>®</sup> Capsules 100 mg), a new oral azole therapeutic for onychomycosis: an analysis based on non-clinical and clinical trial data Open

Makoto Nakano, Yuto Aoki, Hideyo Yamaguchi · 2019

Ravuconazole is a fourth generation azole exerting strong antifungal activity, with low drug-drug interaction and hepatic dysfunction risks. Fosravuconazole l-lysine ethanolate (fosravuconazole; NAILIN^® Capsules 100 mg) was deve…

Serum procalcitonin concentration within 2 days postoperatively accurately predicts outcome after liver resection Open

Yuto Aoki, Nobuhiko Taniai, Masato Yoshioka, Youichi Kawano, Tetsuya Shimizu , et al. · 2018

Correction to: Telomere length of gallbladder epithelium is shortened in patients with congenital biliary dilatation: measurement by quantitative fluorescence in situ hybridization Open

Yuto Aoki, Junko Aida, Youichi Kawano, Kenichi Nakamura, Naotaka Izumiyama‐Shimomura , et al. · 2017

Five-year Survival After Surgical Removal and Gamma Knife Stereotactic Radiosurgery for a Cerebellar Metastasis from an Esophagogastric Junction Cancer: A Case Report and Literature Review Open

Yoshikazu Kanazawa, Itsuo Fujita, Daisuke Kakinuma, Yuto Aoki, Hitoshi Kanno , et al. · 2017

Brain metastases originating from esophageal or gastric cancer are rare, accounting for 2.1-3.3% of all brain tumors registered in Japan. There are no established therapeutic measures for brain metastases, which accordingly have a poor pro…

Protective Effects of Everolimus against <i>N</i>-Methyl-D-aspartic Acid-Induced Retinal Damage in Rats Open

Ikumi Hayashi, Yuto Aoki, Daiki Asano, Hiroko Ushikubo, Asami Mori , et al. · 2015

We previously demonstrated that rapamycin, an inhibitor of the mammalian target of rapamycin (mTOR), protects against N-methyl-D-aspartic acid (NMDA)-induced retinal neurotoxicity, but the mechanism underlying this protection is not fully …

Incidence of Nausea and Vomiting Induced by Oxycodone Administered with Prochlorperazine in Japanese Cancer Patients Open

Takeshi Yamada, Yoshikazu Kanazawa, Yuto Aoki, Eiji Uchida · 2015

The incidence of nausea induced by oxycodone with prochlorperazine was 18.1% in opioid-naïve Japanese inpatients. Female sex may be a risk factor for oxycodone-induced nausea. These results suggest that a clinical study would require 314 p…

Preventive Effects of Rapamycin on Inflammation and Capillary Degeneration in a Rat Model of NMDA-Induced Retinal Injury Open

Yuto Aoki, Tsutomu Nakahara, Daiki Asano, Hiroko Ushikubo, Asami Mori , et al. · 2015

Inhibitors of the mammalian target of rapamycin (mTOR) have been shown to protect against neuronal injury, but the mechanisms underlying this effect are not fully understood. The present study aimed to examine the effects of rapamycin, an …

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