Yutong Wang
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View article: Correction: TET2 gene mutation status associated with poor prognosis of transition zone prostate cancer: a retrospective cohort study based on whole exome sequencing and machine learning models
Correction: TET2 gene mutation status associated with poor prognosis of transition zone prostate cancer: a retrospective cohort study based on whole exome sequencing and machine learning models Open
View article: A clinically relevant pan-cancer prognostic signature derived from T-cell activation immune genes: Experimental validation across malignancies with emphasis on breast cancer
A clinically relevant pan-cancer prognostic signature derived from T-cell activation immune genes: Experimental validation across malignancies with emphasis on breast cancer Open
T-cell activation is widely recognized as a pivotal anti-tumor mechanism, yet emerging evidence reveals functional heterogeneity among T-cell subtypes within the tumor microenvironment (TME). To address this complexity, we developed a pan-…
View article: Biological Zwitterion Betaine‐Assisted Wide Voltage Window and Freeze‐Resistance Hydrogel Electrolyte for Flexible Supercapacitor
Biological Zwitterion Betaine‐Assisted Wide Voltage Window and Freeze‐Resistance Hydrogel Electrolyte for Flexible Supercapacitor Open
Flexible supercapacitors based on hydrogels have developed rapidly, although they still face issues such as low voltage window and easy freezing of gel at low temperatures. Herein, the biological zwitterionic betaine is utilized to lock wa…
View article: Investigation of Intensity Noise Characteristics in Continuous‐Wave Ti: Sapphire Lasers Pumped by 532 nm Fiber Lasers
Investigation of Intensity Noise Characteristics in Continuous‐Wave Ti: Sapphire Lasers Pumped by 532 nm Fiber Lasers Open
Continuous‐wave single‐frequency Ti: sapphire lasers, with their widely tunable wavelength range, are being increasingly used as optical pumping sources for alkali metal atoms in quantum precision measurements, where low‐intensity noise is…
View article: News-Aware Direct Reinforcement Trading for Financial Markets
News-Aware Direct Reinforcement Trading for Financial Markets Open
The financial market is known to be highly sensitive to news. Therefore, effectively incorporating news data into quantitative trading remains an important challenge. Existing approaches typically rely on manually designed rules and/or han…
View article: Is GW190521 a gravitational wave echo of wormhole remnant from another universe?
Is GW190521 a gravitational wave echo of wormhole remnant from another universe? Open
A particularly compelling aspect of the GW190521 event detected by the LIGO-Virgo collaboration is that it has an extremely short duration, and lacks a clearly identifiable inspiral phase usually observed in the binary black holes (BBHs) c…
View article: Fiber laser-pumped Ti:sapphire laser with ultra-low-intensity noise and frequency stabilization for quantum precision measurement applications
Fiber laser-pumped Ti:sapphire laser with ultra-low-intensity noise and frequency stabilization for quantum precision measurement applications Open
We developed a fiber-laser-pumped Ti:sapphire laser system designed for quantum precision measurement applications. By employing a 35 W single-frequency 532 nm fiber laser as the pump source, the system delivered continuous-wave output pow…
View article: Design and dynamics of space- station-based one-degree-of-freedom repeatedly deployable exposure platform
Design and dynamics of space- station-based one-degree-of-freedom repeatedly deployable exposure platform Open
View article: Recent Progress in Flexible Wearable Sensors Utilizing Conductive Hydrogels for Sports Applications: Characteristics, Mechanisms, and Modification Strategies
Recent Progress in Flexible Wearable Sensors Utilizing Conductive Hydrogels for Sports Applications: Characteristics, Mechanisms, and Modification Strategies Open
Conductive hydrogels demonstrate substantial potential for flexible wearable sensors in motion monitoring, owing to their unique physicochemical properties; however, current implementations still confront persistent challenges in long-term…
View article: Phenolic compounds, antioxidant and α-glucosidase inhibitory activities from moringa oleifera seed by-products
Phenolic compounds, antioxidant and α-glucosidase inhibitory activities from moringa oleifera seed by-products Open
View article: Osteoimmunology and aging: Mechanisms, implications, and therapeutic perspectives
Osteoimmunology and aging: Mechanisms, implications, and therapeutic perspectives Open
Osteoimmunology is an interdisciplinary study of the interaction between the immune system and the skeletal system, aiming to reveal the immune regulation mechanisms that affect bone health and disease. Aging is a macro concept, which is n…
View article: Front Cover, Volume 4, Number 3, July 2025
Front Cover, Volume 4, Number 3, July 2025 Open
View article: CypA inhibits respiratory syncytial virus (RSV) replication by suppressing glycolysis through the downregulation of PKM2 expression
CypA inhibits respiratory syncytial virus (RSV) replication by suppressing glycolysis through the downregulation of PKM2 expression Open
The “Warburg effect,” a type of metabolic reprogramming characterized by enhanced glycolysis even in the presence of oxygen, is frequently observed in tumor cells and has also been detected in cells infected with viruses. Our study demonst…
View article: REAL-Prover: Retrieval Augmented Lean Prover for Mathematical Reasoning
REAL-Prover: Retrieval Augmented Lean Prover for Mathematical Reasoning Open
Nowadays, formal theorem provers have made monumental progress on high-school and competition-level mathematics, but few of them generalize to more advanced mathematics. In this paper, we present REAL-Prover, a new open-source stepwise the…
View article: Baoshentongluo Formula relieves podocyte injury in diabetic kidney disease through regulating mitophagy via PINK1/Parkin signaling pathway
Baoshentongluo Formula relieves podocyte injury in diabetic kidney disease through regulating mitophagy via PINK1/Parkin signaling pathway Open
Introduction Diabetic kidney disease (DKD) progression is strongly associated with podocyte mitochondrial dysfunction. The clinically effective Chinese herbal Baoshentongluo formula (BSTL) has demonstrated significant proteinuria reduction…
View article: A fast deep-learning approach to probing primordial black hole populations in gravitational wave events
A fast deep-learning approach to probing primordial black hole populations in gravitational wave events Open
Primordial black holes (PBHs), envisioned as a compelling dark matter candidate and a window onto early-Universe physics, may contribute to the part of the gravitational-wave (GW) signals detected by the LIGO-Virgo-KAGRA network. Tradition…
View article: Thermo‐magnetic soft robot for adaptive locomotion and delivery
Thermo‐magnetic soft robot for adaptive locomotion and delivery Open
Soft robots based on stimuli‐responsive materials, such as those responsive to thermal, magnetic, or light stimuli, hold great potential for adaptive locomotion and multifunctionality in complex environments. Among these, liquid crystal el…
View article: TET2 gene mutation status associated with poor prognosis of transition zone prostate cancer: a retrospective cohort study based on whole exome sequencing and machine learning models
TET2 gene mutation status associated with poor prognosis of transition zone prostate cancer: a retrospective cohort study based on whole exome sequencing and machine learning models Open
Background Prostate cancer (PCa) in the transition zone (TZ) is uncommon and often poses challenges for early diagnosis, but its genomic determinants and therapeutic vulnerabilities remain poorly characterized. Methods Tumor mutational lan…
View article: Low-cost and easily prepared rewritable silica photonic crystal pigment used for paper and textile
Low-cost and easily prepared rewritable silica photonic crystal pigment used for paper and textile Open
By serving aqueous microdroplet in reversed-phase microemulsion as sol-gel reaction space, and reaction condition was just mild stationary, then various sizes of monodispersed silica nanoparticles could be readily constructed without any s…
View article: Integrated Analysis of the Anoikis‐Related Signature Identifies Rac Family Small GTPase 3 as a Novel Tumor‐Promoter Gene in Hepatocellular Carcinoma
Integrated Analysis of the Anoikis‐Related Signature Identifies Rac Family Small GTPase 3 as a Novel Tumor‐Promoter Gene in Hepatocellular Carcinoma Open
Anoikis resistance in hepatocellular carcinoma (HCC) cells boosts survival and metastasis. This study aimed to establish an anoikis‐related genes (ARGs)‐based model for predicting HCC patients’ outcomes and investigate the clinicopathologi…
View article: Integrated RNA-Seq and Metabolomics Analyses of Biological Processes and Metabolic Pathways Involved in Seed Development in Arachis hypogaea L.
Integrated RNA-Seq and Metabolomics Analyses of Biological Processes and Metabolic Pathways Involved in Seed Development in Arachis hypogaea L. Open
In peanut cultivation, fertility and seed development are essential for fruit quality and yield, while pod number per plant, seed number per pod, kernel weight, and seed size are indicators of peanut yield. In this study, metabolomic and R…
View article: Investigating the response of China's surface ozone concentration to the future changes of multiple factors
Investigating the response of China's surface ozone concentration to the future changes of multiple factors Open
Climate change and associated human response are supposed to greatly alter surface ozone (O3), an air pollutant generated through photochemical reactions involving both anthropogenic and biogenic precursors. However, a comprehensive evalua…
View article: Adsorption and Separation by Flexible MOFs
Adsorption and Separation by Flexible MOFs Open
Flexible metal–organic frameworks (MOFs) offer unique opportunities due to their dynamic structural adaptability. This review explores the impact of flexibility on gas adsorption, highlighting key concepts for gas storage and separation. S…
View article: Overexpression of Apolipoprotein A-I Alleviates Insulin Resistance in MASLD Mice Through the PPARα Pathway
Overexpression of Apolipoprotein A-I Alleviates Insulin Resistance in MASLD Mice Through the PPARα Pathway Open
Insulin resistance (IR) is one of the important causes of metabolic dysfunction-associated steatotic liver disease (MASLD). Apolipoprotein A-I (apoA-I) is secreted primarily by hepatocytes and plays an essential role in reverse cholesterol…
View article: Clerodendrum trichotomum Thunb.: a review on phytochemical composition and pharmacological activities
Clerodendrum trichotomum Thunb.: a review on phytochemical composition and pharmacological activities Open
Clerodendrum trichotomum Thunb. ( C . trichotomum ) is a shrub or tree of the genus Clerodendrum , family Lamiaceae, which is widely distributed in China, Korea, India, Japan and Philippines. C . trichotomum is a kind of medicinal and edib…
View article: Development Status of Dynamic Sealing Technology and Discussion on Advanced Sealing Technologies
Development Status of Dynamic Sealing Technology and Discussion on Advanced Sealing Technologies Open
This paper reviews the current state of dynamic sealing technologies, examining the challenges faced by conventional sealing methods under complex working conditions, such as high temperature, high pressure, and corrosive environments. It …
View article: Numerical Monochromatization Coherent Diffraction Imaging of High-Order Harmonics
Numerical Monochromatization Coherent Diffraction Imaging of High-Order Harmonics Open
View article: Lifestyle-Associated Serum Metabolites Profiling in Relation to Risk of Late-Onset Psoriasis
Lifestyle-Associated Serum Metabolites Profiling in Relation to Risk of Late-Onset Psoriasis Open
View article: Improved Few‐Shot Object Detection Method Based on Faster R‐CNN
Improved Few‐Shot Object Detection Method Based on Faster R‐CNN Open
Uneven distribution of object features and insufficient feature learning significantly affect the accuracy and generalizability of existing detection methods. This paper proposes an improved two‐stage few‐shot object detection method that …
View article: WorldCuisines: A Massive-Scale Benchmark for Multilingual and Multicultural Visual Question Answering on Global Cuisines
WorldCuisines: A Massive-Scale Benchmark for Multilingual and Multicultural Visual Question Answering on Global Cuisines Open
Vision Language Models (VLMs) often struggle with culture-specific knowledge, particularly in languages other than English and in underrepresented cultural contexts. To evaluate their understanding of such knowledge, we introduce WorldCuis…