Yuwen Lu
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View article: Effects of seated Baduanjin training modalities on body composition, muscle strength, and gait parameters in older adults: A cluster-randomised controlled trial
Effects of seated Baduanjin training modalities on body composition, muscle strength, and gait parameters in older adults: A cluster-randomised controlled trial Open
View article: TL-ResNet50-SE: An Attention-Enhanced Transfer Learning Model for Surface Defect Detection in Solid Wood Panels
TL-ResNet50-SE: An Attention-Enhanced Transfer Learning Model for Surface Defect Detection in Solid Wood Panels Open
Traditional surface defect detection methods for solid wood panels have gradually exposed many drawbacks, such as poor performance of the detection model, low detection efficiency, and the scarcity of defect detection models applied to woo…
View article: Reversal of Stress‐Induced PIEZO1 Elevation with Mechanically Adapted Epicardial Patch for Myocardial Infarction Treatment
Reversal of Stress‐Induced PIEZO1 Elevation with Mechanically Adapted Epicardial Patch for Myocardial Infarction Treatment Open
Elevated expression of the mechanosensitive ion channel PIEZO1 in response to abnormal mechanical stimuli is implicated in many diseases, including myocardial infarction (MI). However, no effective strategy is currently available to normal…
View article: A plant viral effector subverts <scp>FER</scp>‐<scp>RALF1</scp> module‐mediated intracellular immunity
A plant viral effector subverts <span>FER</span>‐<span>RALF1</span> module‐mediated intracellular immunity Open
Summary The receptor‐like kinase FERONIA (FER) is a prominent member of the Catharanthus roseus RLK1 (CrRLK1L) family, functioning as a modulator of immune receptor kinase complex formation in response to rapid alkalinization factors (RALF…
View article: Research on the Thermal Conductivity and Microstructure of Calcium Lignosulfonate-Magnesium Oxide Solidified Loess
Research on the Thermal Conductivity and Microstructure of Calcium Lignosulfonate-Magnesium Oxide Solidified Loess Open
Loess, characterized by high porosity, a loose structure, and weak cementation, is highly prone to deformation and cracking under thermal stress, which significantly affects the bearing capacity of foundations and the stability of undergro…
View article: Potato Type I Protease Inhibitor Mediates Host Defence Against Potato Virus X Infection by Interacting With a Viral <scp>RNA</scp> Silencing Suppressor
Potato Type I Protease Inhibitor Mediates Host Defence Against Potato Virus X Infection by Interacting With a Viral <span>RNA</span> Silencing Suppressor Open
Counteracting plant RNA silencing ensures successful viral infection. The P25 protein encoded by potato virus X (PVX) is a multifunctional protein that acts as a viral RNA silencing suppressor (VSR). In this study, we screened out a potato…
View article: Profiling of small RNAs derived from tomato brown rugose fruit virus in infected Solanum lycopersicum plants by deep sequencing
Profiling of small RNAs derived from tomato brown rugose fruit virus in infected Solanum lycopersicum plants by deep sequencing Open
Tomato brown rugose fruit virus (ToBRFV) is an emerging, rapidly spreading virus belonging to the genus Tobamovirus which seriously decreases tomato yields. RNA silencing is an evolutionarily conserved antiviral mechanism. In virus-infecte…
View article: Cucumber Green Mottle Mosaic Virus Coat Protein Hijacks Mitochondrial <scp>ATPδ</scp> to Promote Viral Infection
Cucumber Green Mottle Mosaic Virus Coat Protein Hijacks Mitochondrial <span>ATPδ</span> to Promote Viral Infection Open
The production and scavenging of reactive oxygen species (ROS) are critical for plants to adapt to biotic and abiotic stresses. In this study, we investigated the interaction between the coat protein (CP) of cucumber green mottle mosaic vi…
View article: Epicardial transplantation of antioxidant polyurethane scaffold based human amniotic epithelial stem cell patch for myocardial infarction treatment
Epicardial transplantation of antioxidant polyurethane scaffold based human amniotic epithelial stem cell patch for myocardial infarction treatment Open
Myocardial infarction (MI) is a leading cause of death globally. Stem cell therapy is considered a potential strategy for MI treatment. Transplantation of classic stem cells including embryonic, induced pluripotent and cardiac stem cells e…
View article: Low-dose of oligosaccharins boosts antiviral immunity through induction of multiple defense pathways in rice
Low-dose of oligosaccharins boosts antiviral immunity through induction of multiple defense pathways in rice Open
Oligosaccharins, widely recognized as plant immunity inducers, have been applied and studied for enhancing antiviral defenses in rice over the years. However, due to the complex induction mechanism in rice, further studies are needed. In t…
View article: Transcriptome Analysis of Tomato Leaves Reveals Candidate Genes Responsive to Tomato Brown Rugose Fruit Virus Infection
Transcriptome Analysis of Tomato Leaves Reveals Candidate Genes Responsive to Tomato Brown Rugose Fruit Virus Infection Open
Tomato brown rugose fruit virus (ToBRFV) is a newly-emerging tobamovirus which was first reported on tomatoes in Israel and Jordan, and which has now spread rapidly in Asia, Europe, North America, and Africa. ToBRFV can overcome the resist…
View article: Adoption of the 2A Ribosomal Skip Principle to Track Assembled Virions of Pepper Mild Mottle Virus in Nicotiana benthamiana
Adoption of the 2A Ribosomal Skip Principle to Track Assembled Virions of Pepper Mild Mottle Virus in Nicotiana benthamiana Open
The coat protein (CP) is an important structural protein that plays many functional roles during the viral cycle. In this study, the CP of pepper mild mottle virus (PMMoV) was genetically fused to GFP using the foot-and-mouth disease virus…
View article: Integrated <scp>ATAC</scp> ‐seq and <scp>RNA</scp> ‐seq data analysis identifies transcription factors related to rice stripe virus infection in <i>Oryza sativa</i>
Integrated <span>ATAC</span> ‐seq and <span>RNA</span> ‐seq data analysis identifies transcription factors related to rice stripe virus infection in <i>Oryza sativa</i> Open
Animal studies have shown that virus infection causes changes in host chromatin accessibility, but little is known about changes in chromatin accessibility of plants infected by viruses and its potential impact. Here, rice infected by rice…
View article: Histone deacetylase OsHDA706 orchestrates rice broad-spectrum antiviral immunity and is impeded by a viral effector
Histone deacetylase OsHDA706 orchestrates rice broad-spectrum antiviral immunity and is impeded by a viral effector Open
Lysine acetylation is a dynamic post-translational modification of proteins. Extensive studies have revealed that the acetylation modulated by histone acetyltransferases and histone deacetylases (HDACs) plays a crucial role in regulating p…
View article: Analysis of the Unintended Effects of the Bacillus thuringiensis Insecticidal Protein in Genetically Modified Rice Using Untargeted Transcriptomics
Analysis of the Unintended Effects of the Bacillus thuringiensis Insecticidal Protein in Genetically Modified Rice Using Untargeted Transcriptomics Open
The safety and unintended effects of genetically modified (GM) crops have been the focus of public attention. Transcriptome analysis is a powerful tool to assess the potential impact of genetic modification on plant genomes. In this study,…
View article: The nanovirus <scp>U2</scp> protein suppresses <scp>RNA</scp> silencing via three conserved cysteine residues
The nanovirus <span>U2</span> protein suppresses <span>RNA</span> silencing via three conserved cysteine residues Open
Nanoviruses have multipartite, circular, single‐stranded DNA genomes and cause huge production losses in legumes and other crops. No viral suppressor of RNA silencing (VSR) has yet been reported from a member of the genus Nanovirus. Here, …
View article: Qualitative and Quantitative Detection of CRISPR-Associated Cas Gene in Gene-Edited Foods
Qualitative and Quantitative Detection of CRISPR-Associated Cas Gene in Gene-Edited Foods Open
Effective regulation of gene-edited products and resolution of public concerns are the prerequisites for the industrialization of gene-edited crops and their derived foods. CRISPR-associated protein, the core element of the CRISPR system, …
View article: Horizontally Transferred Salivary Protein Promotes Insect Feeding by Suppressing Ferredoxin-Mediated Plant Defenses
Horizontally Transferred Salivary Protein Promotes Insect Feeding by Suppressing Ferredoxin-Mediated Plant Defenses Open
Herbivorous insects such as whiteflies, planthoppers, and aphids secrete abundant orphan proteins to facilitate feeding. Yet, how these genes are recruited and evolve to mediate plant–insect interaction remains unknown. In this study, we r…
View article: StAP1 phage: an effective tool for treating methicillin-resistant Staphylococcus aureus infections
StAP1 phage: an effective tool for treating methicillin-resistant Staphylococcus aureus infections Open
Introduction Staphylococcus aureus infection has long been a serious concern in the medical field, with methicillin-resistant Staphylococcus aureus (MRSA) posing a considerable challenge to public health. Given the escalating bacterial res…
View article: Multi-omics map revealed PPAR<i>α</i>activation protecting against myocardial ischemia-reperfusion injury by maintaining cardiac metabolic homeostasis
Multi-omics map revealed PPAR<i>α</i>activation protecting against myocardial ischemia-reperfusion injury by maintaining cardiac metabolic homeostasis Open
Timely percutaneous coronary intervention is the most effective initial therapy for the acute myocardial infarction (MI). However, the mechanism in energy metabolism underlying time-dependent coronary reperfusion remains largely unknown. H…
View article: Complete genome sequence of a novel mitovirus detected in Colocasia esculenta
Complete genome sequence of a novel mitovirus detected in Colocasia esculenta Open
A novel mitovirus was detected in taro (Colocasia esculenta) growing in Ningbo, China. The complete sequence of Colocasia esculenta associated mitovirus 1 (CeaMV1) was determined by next-generation sequencing combined with RT-PCR and RACE.…
View article: The Additional 15 nt of 5′ UTR in a Novel Recombinant Isolate of Chilli Veinal Mottle Virus in Solanum nigrum L. Is Crucial for Infection
The Additional 15 nt of 5′ UTR in a Novel Recombinant Isolate of Chilli Veinal Mottle Virus in Solanum nigrum L. Is Crucial for Infection Open
An isolate of chilli veinal mottle virus (ChiVMV; genus Potyvirus) of Solanum nigrum L. from southwest China (ChiVMV-YunN/Yuxi) was identified and sequenced (GenBank: OP404087). Comparison with other ChiVMV isolates and recombination analy…
View article: Iatrogenic Pneumothorax during Acupuncture: Case Report
Iatrogenic Pneumothorax during Acupuncture: Case Report Open
Acupuncture treatment in local areas is commonly used to treat pain or soreness; however, acupuncture around the neck or shoulder may be a risk factor for pneumothorax. Herein, we report two cases of iatrogenic pneumothorax after acupunctu…
View article: A biodegradable, flexible photonic patch for in vivo phototherapy
A biodegradable, flexible photonic patch for in vivo phototherapy Open
Diagnostic and therapeutic illumination on internal organs and tissues with high controllability and adaptability in terms of spectrum, area, depth, and intensity remains a major challenge. Here, we present a flexible, biodegradable photon…
View article: Rice stripe virus p2 protein interacts with ATG5 and is targeted for degradation by autophagy
Rice stripe virus p2 protein interacts with ATG5 and is targeted for degradation by autophagy Open
Autophagy can be induced by viral infection and plays antiviral roles in plants, but the underlying mechanism is not well understood. In our previous reports, we have demonstrated that the plant ATG5 plays an essential role in activating a…
View article: Pepper mild mottle virus coat protein interacts with pepper chloroplast outer envelope membrane protein OMP24 to inhibit antiviral immunity in plants
Pepper mild mottle virus coat protein interacts with pepper chloroplast outer envelope membrane protein OMP24 to inhibit antiviral immunity in plants Open
Pepper mild mottle virus (PMMoV) is a devastating viral pathogen of pepper (Capsicum annuum) but it is unclear whether and how peppers protect against PMMoV infection. The expression of the chloroplast outer membrane protein 24 (OMP24) of …
View article: Selection and Validation of Reference Genes for RT-qPCR Analysis of Gene Expression in Nicotiana benthamiana upon Single Infections by 11 Positive-Sense Single-Stranded RNA Viruses from Four Genera
Selection and Validation of Reference Genes for RT-qPCR Analysis of Gene Expression in Nicotiana benthamiana upon Single Infections by 11 Positive-Sense Single-Stranded RNA Viruses from Four Genera Open
Quantitative real-time PCR (RT-qPCR) is a widely used method for studying alterations in gene expression upon infections caused by diverse pathogens such as viruses. Positive-sense single-stranded (ss(+)) RNA viruses form a major part of a…
View article: Construction of chimeric viruses based on pepper mild mottle virus using a modified Cre/loxP system
Construction of chimeric viruses based on pepper mild mottle virus using a modified Cre/loxP system Open
Cre/loxP, a site-specific recombination system, has been widely used for various purposes, including chromosomal translocations, generation of marker-free transgenic plants, tissue-specific activation of a reporter gene and efficient heter…
View article: Bacteriophage-Resistant Mutant of Enterococcus faecalis Is Impaired in Biofilm Formation
Bacteriophage-Resistant Mutant of Enterococcus faecalis Is Impaired in Biofilm Formation Open
Enterococcus faecalis is a common gram-positive non-spore-forming bacterium in nature and is found in the upper respiratory tract, intestine, and mouth of healthy people. E. faecalis is also one of the common pathogens causing nosocomial i…
View article: Acidic dileucine motifs in the cylindrical inclusion protein of turnip mosaic virus are crucial for endosomal targeting and viral replication
Acidic dileucine motifs in the cylindrical inclusion protein of turnip mosaic virus are crucial for endosomal targeting and viral replication Open
Previously we reported that the multifunctional cylindrical inclusion (CI) protein of turnip mosaic virus (TuMV) is targeted to endosomes through the interaction with the medium subunit of adaptor protein complex 2 (AP2β), which is essenti…