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View article: Hepatic steatosis and pyroptosis are induced by the hepatitis B virus X protein via B56α-METTL3 interaction-mediated m6A modification of the NLRP3 mRNA
Hepatic steatosis and pyroptosis are induced by the hepatitis B virus X protein via B56α-METTL3 interaction-mediated m6A modification of the NLRP3 mRNA Open
Metabolic dysfunction-associated steatohepatitis (MASH) is one of the fastest-growing chronic liver diseases and is characterized by excessive steatosis, inflammation, and progressive liver injury. The hepatitis B virus (HBV) X protein (HB…
View article: <i>MALAT1</i> promotes malignancy of HBV-related hepatocellular carcinoma by regulating IGF2BP3-mediated nuclear-cytoplasmic shuttling
<i>MALAT1</i> promotes malignancy of HBV-related hepatocellular carcinoma by regulating IGF2BP3-mediated nuclear-cytoplasmic shuttling Open
Hepatitis B virus (HBV) X protein (HBx) plays a critical role in the progression of HBV-related hepatocellular carcinoma (HCC). Long non-coding RNAs (lncRNAs) regulate various biological processes and contribute to HCC development, with th…
View article: Erratum to: Facile preparation and property analyses of L-CNC/SiO2-based composite superhydrophobic coating
Erratum to: Facile preparation and property analyses of L-CNC/SiO2-based composite superhydrophobic coating Open
View article: Causal Associations of Epigenetic Age Acceleration With Stroke and Its Functional Outcome: A Two‐Sample, Two‐Step Mendelian Randomization Study
Causal Associations of Epigenetic Age Acceleration With Stroke and Its Functional Outcome: A Two‐Sample, Two‐Step Mendelian Randomization Study Open
Background Emerging evidence from observational studies suggested that epigenetic age acceleration may result in an increased incidence of stroke and poorer functional outcomes after a stroke. However, the causality of these associations r…
View article: Immunological Insights into the Causal Link Between Arthritis, Osteoarthritis, and Frailty: An Integrated Analytical Study
Immunological Insights into the Causal Link Between Arthritis, Osteoarthritis, and Frailty: An Integrated Analytical Study Open
Background: Previous observational studies have observed associations between rheumatoid arthritis (RA), knee osteoarthritis (KOA), hip osteoarthritis (HOA), and frailty, but the causal relationships remain unestablished. Objecti…
View article: Multi-Scale Heatmap Regression with Structural Prior and Graph-Aware Refinement for Robust Cephalometric Landmark Localization
Multi-Scale Heatmap Regression with Structural Prior and Graph-Aware Refinement for Robust Cephalometric Landmark Localization Open
View article: CONDEN-FI: Consistency and Diversity Learning-based Multi-View Unsupervised Feature and In-stance Co-Selection
CONDEN-FI: Consistency and Diversity Learning-based Multi-View Unsupervised Feature and In-stance Co-Selection Open
The objective of multi-view unsupervised feature and instance co-selection is to simultaneously iden-tify the most representative features and samples from multi-view unlabeled data, which aids in mit-igating the curse of dimensionality an…
View article: A Cantonese Restaurant Review Dataset for Aspect Category Sentiment Analysis with XLM-RoBERTa
A Cantonese Restaurant Review Dataset for Aspect Category Sentiment Analysis with XLM-RoBERTa Open
The volume of online consumer reviews has surged as e-commerce continues to grow, providing valuable insights for both consumers and business owners. Aspect Category Based Sentiment Analysis (ACSA) identifies sentiment polarity based on sp…
View article: Temporal and spatial characteristics of carbon storage and its response to land-use change in Chengdu, China
Temporal and spatial characteristics of carbon storage and its response to land-use change in Chengdu, China Open
The accurate monitoring of the dynamic relationship between land use and carbon storage can provide a scientific basis for the government to formulate carbon emission reduction policies and promote the green development of cities, achievin…
View article: Analysis of lumbar spine loading during walking in patients with chronic low back pain and healthy controls: An OpenSim-Based study
Analysis of lumbar spine loading during walking in patients with chronic low back pain and healthy controls: An OpenSim-Based study Open
Low back pain (LBP) is one of the most prevalent and disabling disease worldwide. However, the specific biomechanical changes due to LBP are still controversial. The purpose of this study was to estimate the lumbar and lower limb kinematic…
View article: Multiple reports on the causal relationship between various chronic pain and gut microbiota: a two-sample Mendelian randomization study
Multiple reports on the causal relationship between various chronic pain and gut microbiota: a two-sample Mendelian randomization study Open
Background Previous evidence suggests a link between gut microbiota and chronic pain, but the causal relationship is not yet fully understood. Methods We categorized gut microbiota based on phylum, class, order, family, and genus levels an…
View article: Superior effectiveness and acceptability of saliva samples for the detection of SARS-CoV-2 in China
Superior effectiveness and acceptability of saliva samples for the detection of SARS-CoV-2 in China Open
View article: Segmenting Ischemic Penumbra and Infarct Core Simultaneously on Non-Contrast CT of Patients with Acute Ischemic Stroke Using Novel Convolutional Neural Network
Segmenting Ischemic Penumbra and Infarct Core Simultaneously on Non-Contrast CT of Patients with Acute Ischemic Stroke Using Novel Convolutional Neural Network Open
Differentiating between a salvageable Ischemic Penumbra (IP) and an irreversibly damaged Infarct Core (IC) is important for therapy decision making for acute ischemic stroke (AIS) patients. Existing methods rely on Computed Tomography Perf…
View article: Causal Associations of Epigenetic Age Acceleration with Stroke and Its Functional outcome: A Two-Sample, Two-Step Mendelian Randomization Study
Causal Associations of Epigenetic Age Acceleration with Stroke and Its Functional outcome: A Two-Sample, Two-Step Mendelian Randomization Study Open
Background Emerging evidence from observational studies suggested that epigenetic age acceleration may result in an increased incidence of stroke and poorer functional outcomes after a stroke. However, the causality of these associations r…
View article: Developing Flexible and Antibacterial Cellulose Nanofibril/Lignin Nanospheres@Citral Composite Aerogel for High-Efficiency Pm2.5 Capture
Developing Flexible and Antibacterial Cellulose Nanofibril/Lignin Nanospheres@Citral Composite Aerogel for High-Efficiency Pm2.5 Capture Open
View article: Exploring Causal Links Between Gut Microbiota and Geriatric Syndromes: A Two-Sample Mendelian Randomization Analysis
Exploring Causal Links Between Gut Microbiota and Geriatric Syndromes: A Two-Sample Mendelian Randomization Analysis Open
Background: Both observational studies and clinical trials have demonstrated a link between the gut microbiota and the geriatric syndrome. Nevertheless, the exact nature of this relationship, particularly concerning causality, remai…
View article: Relationship between cancer stem cell-related SNPs and survival outcomes in patients with primary lung cancer
Relationship between cancer stem cell-related SNPs and survival outcomes in patients with primary lung cancer Open
Background Cancer stem cells may be the source of cancer-causing mutant cells and are closely related to the prognosis of cancer. Our study aimed to investigate the potential association between single-nucleotide polymorphisms (SNPs) of ca…
View article: High-repetition-rate and high-beam-quality all-solid-state nanosecond pulsed deep-red Raman laser
High-repetition-rate and high-beam-quality all-solid-state nanosecond pulsed deep-red Raman laser Open
We report on a high-repetition-rate and high-beam-quality all-solid-state nanosecond pulsed deep-red laser source by intracavity second harmonic generation of the actively Q-switched Nd:YVO 4 /KGW Raman laser. The polarization of the 1342 …
View article: Evaluating thermal expansion in fluorides and oxides: Machine learning predictions with connectivity descriptors
Evaluating thermal expansion in fluorides and oxides: Machine learning predictions with connectivity descriptors Open
Open framework structures (e.g., ScF 3 , Sc 2 W 3 O 12 , etc.) exhibit significant potential for thermal expansion tailoring owing to their high atomic vibrational degrees of freedom and diverse connectivity between polyhedral units, displ…
View article: Pattern Matching of Industrial Alarm Floods Using Word Embedding and Dynamic Time Warping
Pattern Matching of Industrial Alarm Floods Using Word Embedding and Dynamic Time Warping Open
Dear Editor, This letter proposes a new pattern matching method based on word embedding and dynamic time warping (DTW) to identify groups of similar alarm floods. First, alarm messages are transformed into numeric values that represent ala…
View article: Developing Cellulose Nanofibrils/Na-Montmorillonite Composite Air Filter with Efficient Filtration Ability for Pm2.5 and Adsorption of Formaldehyde
Developing Cellulose Nanofibrils/Na-Montmorillonite Composite Air Filter with Efficient Filtration Ability for Pm2.5 and Adsorption of Formaldehyde Open
View article: Knowledge Graph: Applications in Tracing the Source of Large-Scale Outbreak — Beijing Municipality, China, 2020–2021
Knowledge Graph: Applications in Tracing the Source of Large-Scale Outbreak — Beijing Municipality, China, 2020–2021 Open
The KG model is a promising tool for predicting and controlling future COVID-19 epidemic waves and other infectious disease pandemics. By automatically inferring the source of infection, limited resources can be used efficiently to detect …
View article: A Study of the Impact of Economic Policy Uncertainty in the US and China on the Volatility of the RMB Exchange Rate
A Study of the Impact of Economic Policy Uncertainty in the US and China on the Volatility of the RMB Exchange Rate Open
This paper examines both theoretically and empirically how RMB exchange rate volatility will be affected by China and US economic policy uncertainty. It finds that RMB exchange rate volatility increases when economic policy uncertainty inc…
View article: Study of Carbon Disclosure and Its Differences Between Different Countries Based on the Case of Energy Company Shell
Study of Carbon Disclosure and Its Differences Between Different Countries Based on the Case of Energy Company Shell Open
Low carbon sustainable development is a popular issue in contemporary economic development, after the Kyoto agreement was signed, various countries around the world invested in the establishment of a carbon trading market and the system of…
View article: Association between physical activity and health-related quality of life: time to deterioration model analysis in lung adenocarcinoma
Association between physical activity and health-related quality of life: time to deterioration model analysis in lung adenocarcinoma Open
Background and purpose Health-related quality of life (HRQoL) is a key aspect of care for cancer survivors that can be improved by physical activity. Our aim was to explore the relationship between physical activity and time to deteriorati…
View article: C$^{2}$IMUFS: Complementary and Consensus Learning-based Incomplete Multi-view Unsupervised Feature Selection
C$^{2}$IMUFS: Complementary and Consensus Learning-based Incomplete Multi-view Unsupervised Feature Selection Open
Multi-view unsupervised feature selection (MUFS) has been demonstrated as an effective technique to reduce the dimensionality of multi-view unlabeled data. The existing methods assume that all of views are complete. However, multi-view dat…
View article: The first 20 months of the COVID-19 pandemic: Mortality, intubation and ICU rates among 104,590 patients hospitalized at 21 United States health systems
The first 20 months of the COVID-19 pandemic: Mortality, intubation and ICU rates among 104,590 patients hospitalized at 21 United States health systems Open
Main objective There is limited information on how patient outcomes have changed during the COVID-19 pandemic. This study characterizes changes in mortality, intubation, and ICU admission rates during the first 20 months of the pandemic. S…
View article: Research on the Development of Hospice Care in Beijing
Research on the Development of Hospice Care in Beijing Open
In recent years, hospice care in Beijing has developed rapidly. In order to further promote the development of hospice care in Beijing, this paper first analyzes the current situation of hospice care in Beijing, and then analyzes the exist…
View article: Epidemiology of varicella and effectiveness of varicella vaccine in Hangzhou, China, 2019
Epidemiology of varicella and effectiveness of varicella vaccine in Hangzhou, China, 2019 Open
Background: The varicella vaccine (VarV) is not included in the national childhood immunization schedules in China, although 2-dose VarV (VarV2) were recommended for children at 1 and 4 years of age in Hangzhou since 2014. However, …
View article: Engineering oxygen vacancies in hierarchically Li-rich layered oxide porous microspheres for high-rate lithium ion battery cathode
Engineering oxygen vacancies in hierarchically Li-rich layered oxide porous microspheres for high-rate lithium ion battery cathode Open