Explanipedia

d -Histidine inhibits Streptococcus mutans growth as a potential anti-caries agent Open

Liuchang Yang, Yuxing Chen, Yaqi Chi, Xiaolin Chen, Yiran Zhao , et al. · 2025

These findings suggest that D-His has potential as an anti-caries agent by targeting S. mutans growth and biofilm dynamics.

Preparation and Application of Cellulose-Based Materials with Selective Adsorption of Dyes Open

Linlin Bai, Yuxing Chen, Huiting Ma, Xu Meng · 2025

A cellulose-based material with high adsorption capacity and surface area was developed by selecting appropriate copolymer monomers for structural design. This material was used for selective dye adsorption in wastewater treatment. The cop…

Targeting MAN1B1 potently enhances bladder cancer antitumor immunity via deglycosylation of CD47 Open

Jie Zhang, Chen Zhang, Ruichen Zang, Weiwu Chen, Yining Guo , et al. · 2025

Background Only a few bladder cancer patients benefit from anti‐programmed cell death protein 1/programmed cell death ligand 1 immunotherapy. The cluster of differentiation 47 (CD47) plays an important role in tumor immune evasion. CD47 is…

Omics-based Approach Towards Macrophages: New Perspectives of Biology and Function in the Normal and Diseased Heart Open

Chao Yang, Huajun Li, Yuxing Chen, Wei Zhu, Jianan Wang · 2025

Macrophages play a crucial role not only in maintaining homeostasis but also in initiating inflammatory responses to various forms of stress or injury, thereby contributing to tissue damage while concurrently promoting recovery. Furthermor…

Response to Letter to the Editor on “The associations among platelet count, mean platelet volume, and erectile dysfunction: an observational and Mendelian randomization study” Open

Jingxuan Peng, Jinshun An, Yuxing Chen, Jun Zhou, Boyu Xiang · 2025

Assembly mechanism of the β‐carboxysome shell mediated by the chaperone CcmS Open

Jing Li, Jia‐Xin Deng, X Y Chen, Bo Li, Bo‐Rui Li , et al. · 2025

Summary Carboxysomes are self‐assembled bacterial microcompartments (BMCs) that encapsulate the enzymes RuBisCO and carbonic anhydrase into a proteinaceous shell, enhancing the efficiency of photosynthetic carbon fixation. The chaperone Cc…

Chelonopsis guchengensis, a new species of Lamiaceae from Hubei Province in Central China Open

yuquan xu, Zhixiang Wei, Qiang Fu, Chun‐Lei Xiang, Z. Deng , et al. · 2025

Chelonopsis is a small genus endemic to East Asia. In this study, a new species, C. guchengensis , from Nanhe National Nature Reserve, Gucheng County, Hubei Province is described and illustrated. Molecular phylogenetic analyses based on tw…

High-Performance N-Type Phototransistors Based on Organic / Perovskite-Like Planar Heterojunction for Broad-Spectrum Detection and Neuromorphic Synaptic Applications Open

Yurui Wang, Yuxing Chen, Wei Lin, Bo Yao, Wenhao Wang , et al. · 2025

Dual-Functional Organic/Perovskite Heterojunction Phototransistors Enabling Wide-Spectrum Detection and Synaptic Plasticity Emulation Open

Yurui Wang, Yuxing Chen, Wei Lin, Bo Yao, Wenhao Wang , et al. · 2025

N Protein of Tomato Spotted Wilt Virus Proven to Be Antagonistic Against Tomato Yellow Leaf Curl Virus in Nicotiana benthamiana Open

Ning Qiao, Hongmei Liu, Yuxing Chen, Dezhen Zhang, Jie Liu , et al. · 2024

Two phylogenetically unrelated viruses transmitted by different insect vectors, tomato spotted wilt virus (TSWV) and tomato yellow leaf curl virus (TYLCV), are major threats to tomato and other vegetable production. Although co‐infections …

The associations among platelet count, mean platelet volume, and erectile dysfunction: an observational and Mendelian randomization study Open

Jingxuan Peng, Jinshun An, Yuxing Chen, Jun Zhou, Boyu Xiang · 2024

Background While previous studies have explored the associations and causalities among platelet count (PC), mean platelet volume (MPV), and erectile dysfunction (ED), further investigations are needed to clarify these relationships using a…

The microbiota of wooden cheese ripening boards is a rich source of antimicrobial-producing bacteria againstListeria monocytogenes Open

Yuxing Chen, Ibrahim Zúñiga Chaves, Garret Suen, TuAnh N. Huynh · 2024

Wooden boards are essential tools in cheese ripening and there are accumulating observations suggesting their antimicrobial effect against foodborne bacterial pathogens, such as Listeria monocytogenes . However, poor bacterial recovery of …

TIMD4hiMHCⅡhi Macrophages Preserve Heart Function Through Retnla Open

Danyang Zhang, Xuanhao Wang, Lianlian Zhu, Yuxing Chen, Chao Yang , et al. · 2024

Integration of protein and coding sequences enables mutual augmentation of the language model Open

Heng-Rui Zhao, Meng‐Ting Cheng, Zhu Jinhua, Hao Wang, Xiaoning Yang , et al. · 2024

Recent language models have significantly accelerated our understanding on the massive biological data, using protein or DNA/RNA sequences as a single-language modality. Here we present a dual-language foundation model, which integrates bo…

ScissorBot: Learning Generalizable Scissor Skill for Paper Cutting via Simulation, Imitation, and Sim2Real Open

Jiangran Lyu, Yuxing Chen, Tao Du, Feng Zhu, Huiquan Liu , et al. · 2024

This paper tackles the challenging robotic task of generalizable paper cutting using scissors. In this task, scissors attached to a robot arm are driven to accurately cut curves drawn on the paper, which is hung with the top edge fixed. Du…

Structural insights into human ABCD3-mediated peroxisomal acyl-CoA translocation Open

Yang Li, Zhipeng Chen, Da Xu, Liang Wang, Meng‐Ting Cheng , et al. · 2024

Human ABC transporters ABCD1–3 are all localized on the peroxisomal membrane and participate in the β-oxidation of fatty acyl-CoAs, but they differ from each other in substrate specificity. The transport of branched-chain fatty acids from …

The role of wedge resection and lymph node examination in stage IA lung carcinoid tumors Open

Muyu Li, Qingpeng Zeng, Yuxing Chen, Jun Zhao · 2024

For early-stage PC, wedge resection was not inferior to anatomical resection in terms of OS, while LNE significantly increased the survival in both multivariate and matched studies. The relationship between surgical extent and survival in …

High-Performance UV–Visible Broad Spectral Phototransistors Based on CuPc/Cs3Bi2I9 Heterojunction Open

Yurui Wang, Benfu Jiang, Xijun Zhao, Yuxing Chen, Xinxin Pan , et al. · 2024

Phototransistors are three-terminal photodetectors that usually have a higher photocurrent gain than photodiodes due to the amplification of the gate electrode. In this work, a broad spectral phototransistor based on copper phthalocyanine …

A Study on Street Tree Planting Strategy in Pingtan Island Based on Road Wind Environment Simulation Open

Siqi Gao, Qianxi Chen, Yuxing Chen, Jing Ye, Lingyan Chen · 2024

In this paper, the landscape of typical roadway trees and their planting parameters on Pingtan Island are investigated and analyzed in the field. A three-dimensional model of street trees was created using AutoCAD 2020, and Ansys Fluent 20…

SCSA: Exploring the Synergistic Effects Between Spatial and Channel Attention Open

Yunzhong Si, Huiying Xu, Xinzhong Zhu, Wenhao Zhang, Yao Dong , et al. · 2024

Channel and spatial attentions have respectively brought significant improvements in extracting feature dependencies and spatial structure relations for various downstream vision tasks. While their combination is more beneficial for levera…

Profiling the interplay and coevolution of Microcystis aeruginosa and cyanosiphophage Mic1 Open

Xiaoqian Wang, Kang Du, Chaoyi Chen, Pu Hou, Weifang Li , et al. · 2024

The cyanosiphophage Mic1 specifically infects the bloom-forming Microcystis aeruginosa FACHB 1339 from Lake Chaohu, China. Previous genomic analysis showed that its 92,627 bp double-stranded DNA genome consists of 98 putative open reading …

Multi-Omics Pan-Cancer Analysis of Procollagen N-Propeptidase Gene Family of ADAMTS as Novel Biomarkers to Associate with Prognosis, Tumor Immune Microenvironment, Signaling Pathways, and Drug Sensitivities Open

Yuxing Chen, Chaoyu Xiao, Qingxin Fan, Ye Zhang, Qiu Huang , et al. · 2024

Background: The extracellular matrix (ECM) modeling induced by the metalloproteinases is a vital characteristic for tumor progression. Previous studies mainly focus on the functions of two subgroups of metalloproteinases: matrix metallopro…

Structure of the intact tail machine of Anabaena myophage A-1(L) Open

Rong-Cheng Yu, Feng Yang, Hongyan Zhang, Pu Hou, Kang Du , et al. · 2024

Allosteric regulation of nitrate transporter NRT via the signaling protein PII Open

Bo Li, Xiaoqian Wang, Qin-Yao Li, Da Xu, Jing Li , et al. · 2024

Coordinated carbon and nitrogen metabolism is crucial for bacteria living in the fluctuating environments. Intracellular carbon and nitrogen homeostasis is maintained by a sophisticated network, in which the widespread signaling protein PI…

Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain Open

Yao‐Xu Mao, Zhipeng Chen, Liang Wang, Jie Wang, Cong‐Zhao Zhou , et al. · 2024

Association Between Glycemic Traits and Oesophageal Cancer: a Multivariable Mendelian Randomization Study Open

Yuxing Chen, Qingpeng Zeng, Muyu Li, Keqin Chen, Jun Zhao · 2023

Background Observational studies indicate a potential link between increased blood glucose levels and the development of oesophageal cancer. However, the causal relationship between glycemic traits and oesophageal cancer has not been clari…

Nonribosomal peptide synthetases require dynamic interaction between modular domains Open

Ye-Jun Peng, Xiaoli Zeng, Yuxing Chen, Cong‐Zhao Zhou, Wei Miao , et al. · 2023

Nonribosomal peptide synthetases (NRPSs) are large multidomain enzymes for the synthesis of a variety of bioactive peptides in a modular and pipelined fashion. Here, we investigated how the condensation (C) domain and the adenylation (A) d…

Human SIDT1 mediates dsRNA uptake via its phospholipase activity Open

Cai-Rong Sun, Da Xu, Fengrui Yang, Zhuanghao Hou, Yuyao Luo , et al. · 2023

Glycemic Traits and Oesophageal Cancer a Two-Sample and Multivariable Mendelian Randomization Study Open

Yuxing Chen, Qingpeng Zeng, Muyu Li, Keqin Chen, Jun Zhao · 2023

Background : Observational studies indicate a potential link between increased blood glucose levels and the development of oesophageal cancer. However, the causal relationship between glycemic traits and oesophageal cancer has not been cla…

Task-Oriented Dexterous Hand Pose Synthesis Using Differentiable Grasp Wrench Boundary Estimator Open

Jiayi Chen, Yuxing Chen, Jialiang Zhang, H. Wang · 2023

This work tackles the problem of task-oriented dexterous hand pose synthesis, which involves generating a static hand pose capable of applying a task-specific set of wrenches to manipulate objects. Unlike previous approaches that focus sol…

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