Yuya Koda
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View article: Multiple medication use is associated with increased lymphoma risk in autoimmune diseases: Analysis from the life study
Multiple medication use is associated with increased lymphoma risk in autoimmune diseases: Analysis from the life study Open
Autoimmune diseases (AIDs) are associated with an increased risk of lymphoma. The risk is influenced not only by the nature and severity of the underlying diseases, but also by the type, extent, and duration of immunosuppressive/immunomodu…
View article: Homotopy classification of knotted defects in bounded domains
Homotopy classification of knotted defects in bounded domains Open
Nozaki et al. gave a homotopy classification of the knotted defects of ordered media in three-dimensional space by considering continuous maps from complements of spatial graphs to the order parameter space modulo a certain equivalence rel…
View article: Reducing spheres and weak reducing pairs for Heegaard surfaces in the $3$-sphere
Reducing spheres and weak reducing pairs for Heegaard surfaces in the $3$-sphere Open
Given a Heegaard surface in the $3$-sphere, we show that any non-separating weak reducing pair for the surface admits a reducing sphere that separates the two disks of the pair if and only if the genus of the surface is at most $3$.
View article: Analysis of Hopf solitons as generalized fold maps
Analysis of Hopf solitons as generalized fold maps Open
The Hopf index, a topological invariant that quantifies the linking of preimage fibers, is fundamental to the structure and stability of hopfions. In this work, we propose a new mathematical framework for modeling hopfions with high Hopf i…
View article: Quantum enhancement polynomials associated with the canonical two-element tricbracket
Quantum enhancement polynomials associated with the canonical two-element tricbracket Open
Quantum enhancement polynomials are invariants for oriented links, defined in association with an algebraic structure called a tribracket. In this paper, we focus on the particular case of the canonical two-element tribracket. We prove tha…
View article: Successful Antibiotic Treatment of Phlegmonous Gastritis Following Allogeneic Hematopoietic Stem Cell Transplantation
Successful Antibiotic Treatment of Phlegmonous Gastritis Following Allogeneic Hematopoietic Stem Cell Transplantation Open
Phlegmonous gastritis (PG) is a rare, life-threatening bacterial infection characterized by thickening of the gastric wall. We report a case of PG in a 17-year-old male following allogeneic hematopoietic stem cell transplantation for sever…
View article: Persistent Unilateral Pleural Effusion with Chimeric Antigen Receptor T-cell Infiltration in Primary Mediastinal Large B-cell Lymphoma
Persistent Unilateral Pleural Effusion with Chimeric Antigen Receptor T-cell Infiltration in Primary Mediastinal Large B-cell Lymphoma Open
Pleural effusion following chimeric antigen receptor (CAR) T-cell therapy is typically transient, bilateral, and associated with cytokine release syndrome (CRS). We herein report persistent unilateral massive pleural effusion with CAR T-ce…
View article: Homotopy classification of knotted defects in bounded domains
Homotopy classification of knotted defects in bounded domains Open
Nozaki et.~al.\ gave a homotopy classification of the knotted defects of ordered media in three-dimensional space by considering continuous maps from complements of spatial graphs to the order parameter space modulo a certain equivalence r…
View article: Quantum Knots that Never Come Untied
Quantum Knots that Never Come Untied Open
Lord Kelvin proposed that atoms form hydrodynamic vortex knots. However, they typically untie through reconnections, i. e., local cut-and-slice events, unlike stable vortex unknots such as smoke rings. The same holds in superfluids--quantu…
View article: Homotopy classification of knotted defects in ordered media
Homotopy classification of knotted defects in ordered media Open
We give a homotopy classification of the global defects in ordered media and explain it via the example of biaxial nematic liquid crystals, that is, systems where the order parameter space is the quotient of the three-sphere by the qua…
View article: On the Invalidity of Lemma 2.5 in our previous work on the Powell Conjecture
On the Invalidity of Lemma 2.5 in our previous work on the Powell Conjecture Open
In our previous version entitled ``The reducing sphere complexes for the 3-sphere are connected: a proof of the Powell Conjecture", we claimed to prove the Powell Conjecture, which states that the Goeritz group of the genus-$g$ Heegaard sp…
View article: Essential annuli in genus two handlebody exteriors
Essential annuli in genus two handlebody exteriors Open
We classify all potential configurations of essential annuli in a genus two atoroidal handlebody exterior in the $3$-sphere, building on two recent classifications: the classification of the JSJ-graph of the exterior and the classification…
View article: The Goeritz groups of $(1,1)$-decompositions
The Goeritz groups of $(1,1)$-decompositions Open
A $(g, n)$-decomposition of a link $L$ in a closed orientable $3$-manifold $M$ is a decomposition of $M$ by a closed orientable surface of genus $g$ into two handebodies each intersecting the link $L$ in $n$ trivial arcs. The Goeritz group…
View article: Homotopy classification of knotted defects in ordered media
Homotopy classification of knotted defects in ordered media Open
We give a homotopy classification of the global defects in ordered media, and explain it via the example of biaxial nematic liquid crystals, i.e., systems where the order parameter space is the quotient of the $3$-sphere $S^3$ by the quate…
View article: The Powell Conjecture for the genus-three Heegaard splitting of the $3$-sphere
The Powell Conjecture for the genus-three Heegaard splitting of the $3$-sphere Open
The Powell Conjecture states that the Goeritz group of the Heegaard splitting of the $3$-sphere is finitely generated; furthermore, four specific elements suffice to generate the group. Zupan demonstrated that the conjecture holds if and o…
View article: Diagrammatic criteria for strong irreducibility of Heegaard splittings and finiteness of Goeritz groups
Diagrammatic criteria for strong irreducibility of Heegaard splittings and finiteness of Goeritz groups Open
We give two criteria for diagrams of Heegaard splittings of 3-manifolds. Weaker one of them guarantees that the splitting is strongly irreducible, and the stronger one guarantees in addition that the Goeritz group is finite. They are gener…
View article: Salivary gland swelling as a characteristic manifestation of local cytokine release syndrome after anti-CD19 chimeric antigen receptor T cell therapy: A case series
Salivary gland swelling as a characteristic manifestation of local cytokine release syndrome after anti-CD19 chimeric antigen receptor T cell therapy: A case series Open
Cytokine release syndrome (CRS) is the most common adverse event of chimeric antigen receptor T (CAR-T) cell therapy and is usually characterized by systemic symptoms such as fever, hypotension, and hypoxia. However, there have been severa…
View article: The Impact of Pretransplant Use of Tyrosine Kinase Inhibitors on Allogeneic Stem Cell Transplantation in Patients with Chronic Myeloid Leukemia - A Single-institution Retrospective Study -
The Impact of Pretransplant Use of Tyrosine Kinase Inhibitors on Allogeneic Stem Cell Transplantation in Patients with Chronic Myeloid Leukemia - A Single-institution Retrospective Study - Open
Objective Chronic myeloid leukemia (CML) is a malignant hematological disorder, and allogeneic stem cell transplantation (allo-SCT) was its only curative treatment until the introduction of tyrosine kinase inhibitors (TKIs). Allo-SCT is st…
View article: Divides and hyperbolic volumes
Divides and hyperbolic volumes Open
A divide is the image of a proper and generic immersion of a compact $1$-manifold into the $2$-disk. Due to A'Campo's theory, each divide is associated with a link in the 3-sphere. In this paper, we reveal a hidden hyperbolic structure in …
View article: Positive flow-spines and contact 3-manifolds, II
Positive flow-spines and contact 3-manifolds, II Open
This paper corresponds to Section 8 of arXiv:1912.05774v3 [math.GT]. The contents until Section 7 are published in Annali di Matematica Pura ed Applicata as a separate paper. In that paper, it is proved that for any positive flow-spine P o…
View article: The impact of pretransplant use of tyrosine kinase inhibitors on allogeneic stem cell transplantation in patients with chronic myeloid leukemia - A single-institution retrospective study
The impact of pretransplant use of tyrosine kinase inhibitors on allogeneic stem cell transplantation in patients with chronic myeloid leukemia - A single-institution retrospective study Open
Second- and third-generation (2/3G) tyrosine kinase inhibitors (TKIs) possess excellent treatment effects on chronic myeloid leukemia (CML), and at least one 2/3G TKI is mostly incorporated into the first treatment of CML in all phases. Ho…
View article: Handlebody decompositions of three-manifolds and polycontinuous patterns
Handlebody decompositions of three-manifolds and polycontinuous patterns Open
We introduce the concept of a handlebody decomposition of a three-manifold, a generalization of a Heegaard splitting, or a trisection. We show that two handlebody decompositions of a closed orientable three-manifold are stably equivalent. …
View article: Handlebody decompositions of 3-manifolds and polycontinuous patterns
Handlebody decompositions of 3-manifolds and polycontinuous patterns Open
We introduce the concept of a handlebody decomposition of a 3-manifold, a generalization of a Heegaard splitting, or a trisection. We show that two handlebody decompositions of a closed orientable 3-manifold are stably equivalent. As an ap…
View article: Distance and the Goeritz groups of bridge decompositions
Distance and the Goeritz groups of bridge decompositions Open
We prove that if the distance of a bridge decomposition of a link with\nrespect to a Heegaard splitting of a $3$-manifold is at least $6$, then the\nGoeritz group is a finite group.\n
View article: Presentation of the fundamental groups of complements of shadows
Presentation of the fundamental groups of complements of shadows Open
A shadowed polyhedron is a simple polyhedron equipped with half integers on regions, called gleams, which represents a compact, oriented, smooth 4-manifold. The polyhedron is embedded in the 4-manifold and it is called a shadow of that man…
View article: Adoptive cell therapy using tumor‐infiltrating lymphocytes for melanoma refractory to immune‐checkpoint inhibitors
Adoptive cell therapy using tumor‐infiltrating lymphocytes for melanoma refractory to immune‐checkpoint inhibitors Open
To evaluate the feasibility of adoptive cell therapy (ACT) using ex vivo‐expanded tumor‐infiltrating lymphocytes (TILs) in Japanese patients with melanoma who failed immune‐checkpoint inhibitor therapy, an open‐label, single‐arm, pilot stu…
View article: Distance and the Goeritz groups of bridge decompoitions
Distance and the Goeritz groups of bridge decompoitions Open
We prove that if the distance of a bridge decomposition of a link with respect to a Heegaard splitting of a $3$-manifold is at least $6$, then the Goeritz group is a finite group.
View article: Stable maps and hyperbolic links
Stable maps and hyperbolic links Open
A stable map of a closed orientable $3$-manifold into the real plane is called a stable map of a link in the manifold if the link is contained in the set of definite fold points. We give a complete characterization of the hyperbolic links …
View article: Efficacy of ondansetron against emesis induced by a multiple-day cisplatin-based chemotherapy regimen for malignant lymphoma
Efficacy of ondansetron against emesis induced by a multiple-day cisplatin-based chemotherapy regimen for malignant lymphoma Open
Although NK1RA is generally recommended for cisplatin-containing regimen, our results suggest that ondansetron effectively controlled emesis in patients receiving ESHAP therapy which includes high-dose corticosteroid.
View article: Impact of Specific Antibody Level on Human Herpesvirus 6 Reactivation after Allogeneic Stem Cell Transplantation
Impact of Specific Antibody Level on Human Herpesvirus 6 Reactivation after Allogeneic Stem Cell Transplantation Open
The majority of adults are seropositive for human herpesvirus 6 (HHV-6). HHV-6 reactivation can occur after allogeneic hematopoietic stem cell transplantation (HSCT) and lead to life-threatening central nervous system disorders. In this pr…