Yuyan Dong
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The role of <span>GRB2</span> in diabetes, diabetes complications and related disorders Open
Growth factor receptor‐bound protein 2 (GRB2) is a key adaptor protein involved in multiple signalling pathways, and its dysregulation is associated with various diseases. Type 2 diabetes is a systemic condition characterized by insulin re…
TTI-101 targets STAT3/c-Myc signaling pathway to suppress cervical cancer progression: an integrated experimental and computational analysis Open
TTI-101 exhibited anticancer effects by targeting the STAT3/c-Myc signaling pathway, inducing cell cycle arrest, and promoting apoptosis in CC cells. These findings provide valuable insights into the development of novel therapeutic strate…
Peripheral blood immune cell parameters in patients with high-grade squamous intraepithelial lesion (HSIL) and cervical cancer and their clinical value: a retrospective study Open
Objective The objective of this study was to delineate the profile of peripheral blood lymphocytic indices in patients afflicted with high-grade squamous intraepithelial lesions (HSIL) and cervical neoplasms, and to elucidate the correlati…
Corrigendum: The possible correlation between serum GRB2 levels and carotid atherosclerosis in patients with type 2 diabetes mellitus Open
[This corrects the article DOI: 10.3389/fendo.2022.963191.].
The possible correlation between serum GRB2 levels and carotid atherosclerosis in patients with type 2 diabetes mellitus Open
Background and purpose Growth factor receptor-bound protein 2(GRB2), a bridging protein. An animal study showed that downregulation of GRB2 inhibited the activation of PI3K/AKT/NF-kB pathway which improved lipid accumulation and inflammato…