Chuzhao Lei
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View article: Whole-genome analysis reveals genetic diversity and selection pressure in Sichuan donkey
Whole-genome analysis reveals genetic diversity and selection pressure in Sichuan donkey Open
View article: Integrated transcriptomic and phenotypic analysis reveals tissue-specific regulatory effects of guanidinoacetic acid in cattle
Integrated transcriptomic and phenotypic analysis reveals tissue-specific regulatory effects of guanidinoacetic acid in cattle Open
View article: Evaluation of genetic diversity and selection signals in gayal populations across four countries through whole-genome resequencing
Evaluation of genetic diversity and selection signals in gayal populations across four countries through whole-genome resequencing Open
View article: Rumen Epithelial Transcriptome Analysis Revealed the Regulatory Mechanism of Host Adaptation to Nitrogen Source Replacement Diet in Simmental Cattle
Rumen Epithelial Transcriptome Analysis Revealed the Regulatory Mechanism of Host Adaptation to Nitrogen Source Replacement Diet in Simmental Cattle Open
Soybean meal, a high‐quality protein in ruminant diets, has been explored by farmers and researchers to replace soybean meal with other nitrogen sources to reduce feed costs due to its high price and limited resources. Gelatinized urea is …
View article: Single-nucleus RNA sequencing reveals developmental dynamics and cellular heterogeneity in the mammary gland of young fillies and adult Mongolian mares
Single-nucleus RNA sequencing reveals developmental dynamics and cellular heterogeneity in the mammary gland of young fillies and adult Mongolian mares Open
Mongolian horses are famous for their lactation traits. Their milk contains a high protein content and low levels of fatty acids. Given their superior milk composition and historical use in dairy production across Inner Mongolia and Centra…
View article: Structural Variations Associated with Adaptation and Coat Color in Qinghai‐Tibetan Plateau Cattle
Structural Variations Associated with Adaptation and Coat Color in Qinghai‐Tibetan Plateau Cattle Open
Structural variations (SVs) play crucial roles in the evolutionary adaptation of domesticated animals to natural and human‐controlled environments, but SVs have not been explored in Tibetan cattle, which recently migrated and rapidly adapt…
View article: The CNV map construction and ROH analysis of Pinan cattle
The CNV map construction and ROH analysis of Pinan cattle Open
View article: CircRNA profiling reveals circSMC1B that promotes bovine male germline stem cells proliferation and apoptosis via sponging let-7i
CircRNA profiling reveals circSMC1B that promotes bovine male germline stem cells proliferation and apoptosis via sponging let-7i Open
View article: First report of Blastocystis sp. and Enterocytozoon bieneusi in raptors
First report of Blastocystis sp. and Enterocytozoon bieneusi in raptors Open
Introduction Blastocystis sp . and Enterocytozoon bieneusi are common zoonotic pathogens threatening human and animal health. These parasites are widely distributed in birds, and substantial research on their prevalence has been conducted.…
View article: Whole genome insights into genetic diversity, introgression, and adaptation of Yunnan indigenous cattle of Southwestern China
Whole genome insights into genetic diversity, introgression, and adaptation of Yunnan indigenous cattle of Southwestern China Open
View article: X-chromosome-linked miR-542-5p as a key regulator of sex disparity in rats with adjuvant-induced arthritis by promoting Th17 differentiation
X-chromosome-linked miR-542-5p as a key regulator of sex disparity in rats with adjuvant-induced arthritis by promoting Th17 differentiation Open
View article: Selection Increases Mitonuclear DNA Discordance but Reconciles Incompatibility in African Cattle
Selection Increases Mitonuclear DNA Discordance but Reconciles Incompatibility in African Cattle Open
Mitochondrial function relies on the coordinated interactions between genes in the mitochondrial DNA and nuclear genomes. Imperfect interactions following mitonuclear incompatibility may lead to reduced fitness. Mitochondrial DNA introgres…
View article: Whole-genome resequencing of 391 Chinese donkeys reveals a population structure and provides insights into their morphological and adaptive traits
Whole-genome resequencing of 391 Chinese donkeys reveals a population structure and provides insights into their morphological and adaptive traits Open
View article: Whole-Genome Sequences Revealed Genomic Diversity and Selection Signatures of Dermacentor Silvarum in Shaanxi, China
Whole-Genome Sequences Revealed Genomic Diversity and Selection Signatures of Dermacentor Silvarum in Shaanxi, China Open
View article: Inference of Genetic Diversity, Population Structure, and Selection Signatures in Xiangxi White Buffalo of China Through Whole-Genome Resequencing
Inference of Genetic Diversity, Population Structure, and Selection Signatures in Xiangxi White Buffalo of China Through Whole-Genome Resequencing Open
(1) Background: Buffaloes are crucial livestock species for food and service in tropical and subtropical regions. Buffalo genetics, particularly in indigenous Chinese breeds such as the Xiangxi white buffalo (XWB), remains an intriguing ar…
View article: Evolution and legacy of East Asian aurochs
Evolution and legacy of East Asian aurochs Open
Aurochs (Bos primigenius), once widely distributed in Afro-Eurasia, became extinct in the early 1600 s. However, their phylogeography and relative contributions to domestic cattle remain unknown. In this study, we analyzed 16 genomes of an…
View article: A Whole-Genome Scan Revealed Genomic Features and Selection Footprints of Mengshan Cattle
A Whole-Genome Scan Revealed Genomic Features and Selection Footprints of Mengshan Cattle Open
(1) Background: Mengshan cattle from the Yimeng mountainous region in China stand out as a unique genetic resource, known for their adaptive traits and environmental resilience. However, these cattle are currently endangered and comprehens…
View article: CircDYRK1A regulates bovine myoblasts development by binding miR21‐5p to affect <i>KLF5</i> gene expression
CircDYRK1A regulates bovine myoblasts development by binding miR21‐5p to affect <i>KLF5</i> gene expression Open
Circular RNA (circRNA), a stable ring‐shaped RNA molecule found in eukaryotic cells, plays significant roles in biological regulation, particularly by interfering with transcription factor binding or enhancing gene expression. Using transc…
View article: Identification of Heilongjiang crossbred beef cattle pedigrees and reveals functional genes related to economic traits based on whole-genome SNP data
Identification of Heilongjiang crossbred beef cattle pedigrees and reveals functional genes related to economic traits based on whole-genome SNP data Open
Introduction: To enhance the beef cattle industry, Heilongjiang Province has developed a new Crossbred beef cattle variety through crossbreeding with exotic commercial breeds. This new variety exhibits relatively excellent meat quality, an…
View article: Illuminating Genetic Diversity and Selection Signatures in Matou Goats through Whole-Genome Sequencing Analysis
Illuminating Genetic Diversity and Selection Signatures in Matou Goats through Whole-Genome Sequencing Analysis Open
(1) Background: Matou goats, native to Hunan and Hubei provinces in China, are renowned for their exceptional meat and skin quality. However, a comprehensive whole-genome-based exploration of the genetic architecture of this breed is scant…
View article: Assessing genomic diversity and selection signatures of Rhipicephalus microplus in Shaanxi, China based on whole-genome sequences
Assessing genomic diversity and selection signatures of Rhipicephalus microplus in Shaanxi, China based on whole-genome sequences Open
Background Ticks play a crucial role in transmitting and carrying various disease-causing microorganisms, which poses a significant risk to public health and the growth of the animal farming industry. Research on the whole genome sequence …
View article: Whole-genome sequencing reveals genomic diversity and selection signatures in Xia’nan cattle
Whole-genome sequencing reveals genomic diversity and selection signatures in Xia’nan cattle Open
View article: Correction: Transcriptomics and metabolomics of blood, urine and ovarian follicular fuid of yak at induced estrus stage
Correction: Transcriptomics and metabolomics of blood, urine and ovarian follicular fuid of yak at induced estrus stage Open
View article: Comprehensive whole-genome resequencing unveils genetic diversity and selective signatures of the Xiangdong black goat
Comprehensive whole-genome resequencing unveils genetic diversity and selective signatures of the Xiangdong black goat Open
Xiangdong black goats, indigenous to Hunan Province, China, exhibit remarkable adaptation to challenging environments and possess distinct black coat coloration alongside exceptional meat quality attributes. Despite their significance, com…
View article: Copy number variations within fibroblast growth factor 13 gene influence growth traits and alternative splicing in cattle
Copy number variations within fibroblast growth factor 13 gene influence growth traits and alternative splicing in cattle Open
Previous researches revealed a copy number variation (CNV) region in the bovine fibroblast growth factor 13 (FGF13) gene. However, its effects remain unknown. This study detected the various copy number types in seven Chinese cattle…
View article: Transcriptomics and metabolomics of blood, urine and ovarian follicular fluid of yak at induced estrus stage
Transcriptomics and metabolomics of blood, urine and ovarian follicular fluid of yak at induced estrus stage Open
To gain a deeper understanding of the metabolic differences within and outside the body, as well as changes in transcription levels following estrus in yaks, we conducted transcriptome and metabolome analyses on female yaks in both estrus …
View article: Temperature adaptation patterns in Chinese cattle revealed by <i>TRPM2</i> gene mutation analysis
Temperature adaptation patterns in Chinese cattle revealed by <i>TRPM2</i> gene mutation analysis Open
Cattle are sensitive to temperature fluctuations but adapt well to inclement weather conditions. When environmental temperatures exceed specific thresholds, heat stress becomes a critical concern for cattle. The TRPM2 gene, which re…
View article: Temperature adaptation patterns in Chinese cattle revealed by <i>TRPM2</i> gene mutation analysis
Temperature adaptation patterns in Chinese cattle revealed by <i>TRPM2</i> gene mutation analysis Open
Cattle are sensitive to temperature fluctuations but adapt well to inclement weather conditions. When environmental temperatures exceed specific thresholds, heat stress becomes a critical concern for cattle. The TRPM2 gene, which re…
View article: Global genetic diversity, introgression, and evolutionary adaptation of indicine cattle revealed by whole genome sequencing
Global genetic diversity, introgression, and evolutionary adaptation of indicine cattle revealed by whole genome sequencing Open
Indicine cattle, also referred to as zebu ( Bos taurus indicus ), play a central role in pastoral communities across a wide range of agro-ecosystems, from extremely hot semiarid regions to hot humid tropical regions. However, their adaptiv…
View article: Geographic Distribution of a Missense Mutation in the<i>KRT38</i>Gene and Its Association with Heat Tolerance in Chinese Indigenous Cattle Breeds
Geographic Distribution of a Missense Mutation in the<i>KRT38</i>Gene and Its Association with Heat Tolerance in Chinese Indigenous Cattle Breeds Open
Context China has a vast area across many temperature zones and a variety of cattle breeds. These cattle resources are ideal models to research their adaptability to the environment. The KRT38 gene is an acidic protein, and its coding prod…