Zhen Liu
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View article: Jasmonate Modulates Strawberry Susceptibility to Anthracnose by Activating SnRK2.1 to Regulate the WRKY50‐JAZ5 Module
Jasmonate Modulates Strawberry Susceptibility to Anthracnose by Activating SnRK2.1 to Regulate the WRKY50‐JAZ5 Module Open
Colletotrichum spp., hemibiotrophic fungal pathogens, threaten global strawberry production. Jasmonate (JA) regulates plant‐ Colletotrichum interactions, but its mechanisms remain unclear. Here we demonstrate that both exogenous methyl jas…
View article: Optical multistability in a compact microcavity enabled by near-exceptional coupling
Optical multistability in a compact microcavity enabled by near-exceptional coupling Open
Multistability -- the emergence of multiple stable states under identical conditions -- is a hallmark of nonlinear complexity and an enabling mechanism for multilevel optical memory and photonic computing. Its realization in a compact foot…
View article: Bioinformatic analysis of the potential common pathogenic mechanisms for gastric precancerous lesions and Helicobacter pylori
Bioinformatic analysis of the potential common pathogenic mechanisms for gastric precancerous lesions and Helicobacter pylori Open
Objective Gastric precancerous lesions (GPL) represent a critical stage in the progression from gastritis to gastric cancer (GC). Helicobacter pylori (H. pylori) infection is a significant etiological factor exacerbating the inflammatory-c…
View article: Effect of the Peiyu granules on early miscarriage among women undergoing embryo transfer: a randomized, double-blind, placebo-controlled trial
Effect of the Peiyu granules on early miscarriage among women undergoing embryo transfer: a randomized, double-blind, placebo-controlled trial Open
Objective To evaluate the efficacy and safety of the Peiyu Granules (PYG) compared with placebo on early miscarriage rates among women undergoing embryo transfer. Methods A double-blind, parallel-group randomized clinical trial between Feb…
View article: Exploring potential associations between GLP-1RAs and depressive disorders: a pharmacovigilance study based on FAERS and VigiBase data
Exploring potential associations between GLP-1RAs and depressive disorders: a pharmacovigilance study based on FAERS and VigiBase data Open
View article: Screening and evaluation of purines-degrading lactic acid bacteria isolated from traditional fermented foods in Yunnan Province and their uric acid-lowering effects in vivo
Screening and evaluation of purines-degrading lactic acid bacteria isolated from traditional fermented foods in Yunnan Province and their uric acid-lowering effects in vivo Open
Introduction Traditional fermented foods have recently been recognized for their potential benefits in managing hyperuricemia (HUA) and gout. Methods This study evaluated the purine degradation ability of seventy-eight lactic acid bacteria…
View article: Efficient Somatic Cell Nuclear Transfer by Overcoming Both Pre‐ and Post‐Implantation Epigenetic Barriers
Efficient Somatic Cell Nuclear Transfer by Overcoming Both Pre‐ and Post‐Implantation Epigenetic Barriers Open
Mammalian cloning through somatic cell nuclear transfer (SCNT) involves reprogramming terminally differentiated cells into totipotent embryos. Epigenetic barriers inherited from somatic cells impede reprogramming efficiency and lead to low…
View article: An Intranasal Nanomedicine Functions as Both Potent Broad‐spectrum Viral Inhibitor and Quasi‐Vaccine (Adv. Funct. Mater. 28/2025)
An Intranasal Nanomedicine Functions as Both Potent Broad‐spectrum Viral Inhibitor and Quasi‐Vaccine (Adv. Funct. Mater. 28/2025) Open
View article: Deep learning enhanced deciphering of brain activity maps for discovery of therapeutics for brain disorders
Deep learning enhanced deciphering of brain activity maps for discovery of therapeutics for brain disorders Open
View article: Electronic Homogenization Regulation via Nicotinamide Derivative Ligands for Efficient Blade‐Coated Wide‐Bandgap Perovskite Solar Cells
Electronic Homogenization Regulation via Nicotinamide Derivative Ligands for Efficient Blade‐Coated Wide‐Bandgap Perovskite Solar Cells Open
The spatial heterogeneity of electronic properties mediated by surface terminal disorder is a major limitation to achieving high‐efficiency metal‐halide perovskite photovoltaics. An in‐depth understanding of how molecular configurations af…
View article: Genomic evidence of the blood virome and bacteriome provides insights into prevalence, evolution, and susceptibility-related genes across Eurasian pigs
Genomic evidence of the blood virome and bacteriome provides insights into prevalence, evolution, and susceptibility-related genes across Eurasian pigs Open
View article: An Intranasal Nanomedicine Functions as Both Potent Broad‐spectrum Viral Inhibitor and Quasi‐Vaccine
An Intranasal Nanomedicine Functions as Both Potent Broad‐spectrum Viral Inhibitor and Quasi‐Vaccine Open
Antivirals that exert rapid inhibition and vaccines that provide long‐term prevention are both of paramount importance for the intervening against fatal viral infections. Clearly, it will be highly desirable to integrate the two strategies…
View article: Cascade Fluorescent Sensors Based on Isothermal Signal Amplification for the Detection of Mercury and Silver Ions
Cascade Fluorescent Sensors Based on Isothermal Signal Amplification for the Detection of Mercury and Silver Ions Open
In this study, novel fluorescent DNA biosensors for mercury (Hg2+) and silver (Ag+) ions were developed based on thymine (T)- and cytosine (C)-rich recognition elements in combination with exonuclease III and a mismatch-catalyzed hairpin a…
View article: Highly Holographic Diffraction Efficiency and Recording Stable Macromolecule Photopolymer by Introducing Crosslinker Vinyl-Poss
Highly Holographic Diffraction Efficiency and Recording Stable Macromolecule Photopolymer by Introducing Crosslinker Vinyl-Poss Open
View article: Tri-specific molecularly imprinted lysosomal nanodegrader enables synergistic therapy of cytokine storm
Tri-specific molecularly imprinted lysosomal nanodegrader enables synergistic therapy of cytokine storm Open
A tri-specific molecularly imprinted polymer-based lysosome-targeted chimera was developed for synergistic anti-inflammatory therapy, effectively reducing the level of IL-6, TNF-α, and downstream p-STAT3/NF-κB p65, thereby alleviating cyto…
View article: Highly Holographic Diffraction Efficiency and Recording Stable Macromolecule Photopolymer by Introducing Crosslinker Vinyl-Poss
Highly Holographic Diffraction Efficiency and Recording Stable Macromolecule Photopolymer by Introducing Crosslinker Vinyl-Poss Open
View article: Association of insulin resistance with chronic kidney disease in individuals without diabetes in a community population in South China
Association of insulin resistance with chronic kidney disease in individuals without diabetes in a community population in South China Open
View article: The 1000 Chinese Indigenous Pig Genomes Project provides insights into the genomic architecture of pigs
The 1000 Chinese Indigenous Pig Genomes Project provides insights into the genomic architecture of pigs Open
Pigs play a central role in human livelihoods in China, but a lack of systematic large-scale whole-genome sequencing of Chinese domestic pigs has hindered genetic studies. Here, we present the 1000 Chinese Indigenous Pig Genomes Project se…
View article: LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts
LPS‑mediated adaptation accelerates ecto‑MSCs differentiation into osteoblasts Open
Addressing the repair and regeneration of large bone defects poses significant challenges in bone tissue engineering. Despite the abundant evidence demonstrating the positive role of MSCs in osteogenesis, their limited osteogenic different…
View article: Safety assessment of sulfasalazine: a pharmacovigilance study based on FAERS database
Safety assessment of sulfasalazine: a pharmacovigilance study based on FAERS database Open
Background Sulfasalazine is a widely used anti-inflammatory medication for treating autoimmune disorders such as ulcerative colitis (UC), Crohn’s disease, and rheumatoid arthritis. However, its safety profile has not been systematically ev…
View article: Infection microenvironment-triggered nanoparticles eradicate MRSA by thermally amplified chemodynamic therapy and M1 macrophage
Infection microenvironment-triggered nanoparticles eradicate MRSA by thermally amplified chemodynamic therapy and M1 macrophage Open
It is of great significance to develop a novel approach to treat bacterial infections, as the frequent misuse of antibiotics leads to the serious problem of bacterial resistance. This study proposed antibiotic-free antibacterial nanopartic…
View article: Ultrasonic‐Assisted Biphasic Aqueous Extraction of Polyphenols from <i>Vaccinium Dunalianum</i> Leaves: Optimization, Antioxidant, and Tyrosinase Inhibition Activities
Ultrasonic‐Assisted Biphasic Aqueous Extraction of Polyphenols from <i>Vaccinium Dunalianum</i> Leaves: Optimization, Antioxidant, and Tyrosinase Inhibition Activities Open
To optimize the ultrasonic‐assisted biphasic aqueous extraction conditions for polyphenolic compounds from Vaccinium dunalianum Wight leaves and investigate their antioxidant and tyrosinase inhibition activities, single‐factor experiments …
View article: Astragalus liuaiminii, a new species of Astragalus (Fabaceae) from Xinjiang, China
Astragalus liuaiminii, a new species of Astragalus (Fabaceae) from Xinjiang, China Open
A new species, Astragalus liuaiminii Z. Z. Yang & Q. R. Liu (Fabaceae), is described and illustrated from Xinjiang Province, China. The new species is close to A. wenquanensis S. B. Ho, but differs from the latter by leaves having a single…
View article: Recent advances of molecular imprinting technology for the separation and recognition of complex biological sample systems
Recent advances of molecular imprinting technology for the separation and recognition of complex biological sample systems Open
Given continuous improvements in industrial production and living standards, the analysis and detection of complex biological sample systems has become increasingly important. Common complex biological samples include blood, serum, saliva,…
View article: Infection Microenvironment-Triggered Nanoparticles Eradicate MRSA by Thermally Amplified Chemodynamic Therapy and M1 macrophage
Infection Microenvironment-Triggered Nanoparticles Eradicate MRSA by Thermally Amplified Chemodynamic Therapy and M1 macrophage Open
It is of great significance to develop novel approach to treat bacterial infections, due to the frequent misuse of antibiotics leads to the serious problem of bacterial resistance. In this study, antibiotic-free antibacterial nanoparticles…
View article: Single-cell transcriptome analysis profiling lymphatic invasion-related TME in colorectal cancer
Single-cell transcriptome analysis profiling lymphatic invasion-related TME in colorectal cancer Open
Lymphatic invasion (LI) is extremely aggressive and induces worse prognosis among patients with colorectal cancer (CRC). Thus, it is critical to characterize the cellular and molecular mechanisms underlying LI in order to establish novel a…
View article: Development of a water-soluble Vitamin D drink for enhanced absorption and serum levels
Development of a water-soluble Vitamin D drink for enhanced absorption and serum levels Open
Vitamin D deficiency and insufficiency have been found in general population but especially in women of childbearing age. Although Vitamin D can be obtained from food source (few naturally) and produced from skin sunlight exposure, it can …
View article: A Method for Detecting Five Carbapenemases in Bacteria Based on CRISPR-Cas12a Multiple RPA Rapid Detection Technology
A Method for Detecting Five Carbapenemases in Bacteria Based on CRISPR-Cas12a Multiple RPA Rapid Detection Technology Open
This multi-scene detection method is suitable for screening populations in wild low-resource environments and large-scale indoor crowds. It can be widely used in hospital infection control and prevention and to provide theoretical insights…
View article: Deciphering cellular processes responding to lethality of 17&lt;italic&gt;&beta;&lt;/italic&gt;-estradiol by quantitative phosphoproteomics
Deciphering cellular processes responding to lethality of 17<italic>β</italic>-estradiol by quantitative phosphoproteomics Open
17β-Estradiol (E2), an important endocrine hormone in the mammalian body, participates in the regulation of the physiological functions of the reproductive system, mammary glands, bone, and cardiovascular system, among others. Parad…
View article: Correction: Liu et al. Emergent Peptides of the Antifibrotic Arsenal: Taking Aim at Myofibroblast Promoting Pathways. Biomolecules 2023, 13, 1179
Correction: Liu et al. Emergent Peptides of the Antifibrotic Arsenal: Taking Aim at Myofibroblast Promoting Pathways. Biomolecules 2023, 13, 1179 Open
There was an error in the original publication [...]