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View article: Cell Surface Ion-Seq: Potassium Ion Monitoring in the Colorectal Cancer Cellular Microenvironment Based on Split G-quadruplex Probe
Cell Surface Ion-Seq: Potassium Ion Monitoring in the Colorectal Cancer Cellular Microenvironment Based on Split G-quadruplex Probe Open
Potassium ions (K+) are vital for biological systems and essential cellular functions, making their homeostasis monitoring crucial for investigating electrolyte imbalance symptoms. Antibody-based high-throughput single-cell sequencing enab…
View article: Design and Research for a Gas–water Separator for Pump Cavitation Testing
Design and Research for a Gas–water Separator for Pump Cavitation Testing Open
In open-type cavitation tests, pump inlet air bubbles affect the accuracy of cavitation margin measurements. To improve the accuracy of these measurements, a novel gas–water separation device for pump cavitation testing was designed in thi…
View article: The association of different types of physical activity and diabetes co-morbid depression: A cross-sectional analysis
The association of different types of physical activity and diabetes co-morbid depression: A cross-sectional analysis Open
Background Diabetes co-morbid depression is a significant public health burden. Physical activity (PA) has been suggested as a potential approach to reduce the risk of diabetes co-morbid depression. Different types of PA may have different…
View article: Engineering Lanthanide Ion-Labeled Aptamers for ICP-MS Profiling of Serum-Derived Extracellular Vesicles from Colorectal Cancer
Engineering Lanthanide Ion-Labeled Aptamers for ICP-MS Profiling of Serum-Derived Extracellular Vesicles from Colorectal Cancer Open
Membrane proteins on extracellular vesicles (EVs) derived from clinical serum samples have emerged as promising biomarkers for cancer screening, early diagnosis and prognosis. However, high-throughput profiling of multiple EV proteins with…
View article: Current status of management of immune-related adverse events and practical needs for oncologist education
Current status of management of immune-related adverse events and practical needs for oncologist education Open
Immune checkpoint inhibitors have markedly improved outcomes in patients with multiple advanced malignancies. However, their widespread use has markedly increased the incidence of immune-related adverse events (irAEs). irAEs can affect a w…
View article: Physical analysis of PRC reactor based on zero power physical experiments
Physical analysis of PRC reactor based on zero power physical experiments Open
The Pulsed Reactor of China (PRC) can provide a stable neutron field for neutron science applications, with a steady-state rated power of 1 MW. This study aims to provide a comprehensive physical analysis of the PRC reactor through an inte…
View article: Research advances of extracellular vesicles in lung diseases
Research advances of extracellular vesicles in lung diseases Open
The lung is a vital organ in the respiratory system, and there is a critical need to develop more effective methods for lung health management. Extracellular vesicles (EVs) play an important role in intercellular communication. They exhibi…
View article: Luminosity measurement with the LHCb RICH detectors in Run 3
Luminosity measurement with the LHCb RICH detectors in Run 3 Open
The LHCb Ring-Imaging Cherenkov detectors are built to provide charged hadron identification over a large range of momentum. The upgraded detectors are also capable of providing an independent measurement of the luminosity for the LHCb exp…
View article: StreamMel: Real-Time Zero-shot Text-to-Speech via Interleaved Continuous Autoregressive Modeling
StreamMel: Real-Time Zero-shot Text-to-Speech via Interleaved Continuous Autoregressive Modeling Open
Recent advances in zero-shot text-to-speech (TTS) synthesis have achieved high-quality speech generation for unseen speakers, but most systems remain unsuitable for real-time applications because of their offline design. Current streaming …
View article: Efficacy of Cylindrical Annular Refractive Elements (CARE) Spectacle Lenses in Slowing Myopia Progression Over 2 Years
Efficacy of Cylindrical Annular Refractive Elements (CARE) Spectacle Lenses in Slowing Myopia Progression Over 2 Years Open
Over a 2-year period, lenses incorporating CARE significantly slowed myopia progression compared with SV lenses.
View article: Astra: Toward General-Purpose Mobile Robots via Hierarchical Multimodal Learning
Astra: Toward General-Purpose Mobile Robots via Hierarchical Multimodal Learning Open
Modern robot navigation systems encounter difficulties in diverse and complex indoor environments. Traditional approaches rely on multiple modules with small models or rule-based systems and thus lack adaptability to new environments. To a…
View article: Knowledge-guided Contextual Gene Set Analysis Using Large Language Models.
Knowledge-guided Contextual Gene Set Analysis Using Large Language Models. Open
Gene set analysis (GSA) is a foundational approach for interpreting genomic data of diseases by linking genes to biological processes. However, conventional GSA methods overlook clinical context of the analyses, often generating long lists…
View article: Human Herpesvirus‐6 Infectious Meningitis With Lymphadenitis in an Immunocompetent Adult
Human Herpesvirus‐6 Infectious Meningitis With Lymphadenitis in an Immunocompetent Adult Open
Purpose Human Herpesvirus 6 (HHV‐6) infections are primarily observed in immunocompromised individuals, such as those with acquired immunodeficiency syndrome or organ transplant recipients. However, its role as a pathogen in immunocompeten…
Reconfigurable terahertz optoelectronic logic through charge-density-wave phase engineering Open
Charge density waves, manifestations of strongly correlated electronic states in low-dimensional materials, exhibit collective quantum phenomena that enable phase-coherent electronic manipulation. Conventional approaches face limitations i…
View article: Head‐to‐head comparison between ACQ and FRET in probing polymeric micelles
Head‐to‐head comparison between ACQ and FRET in probing polymeric micelles Open
Environmentally responsive fluorophores, such as those with aggregation‐caused quenching (ACQ) and Förster resonance energy transfer (FRET) properties, are widely used to track nanocarriers while minimizing artifacts. This study compares t…
View article: Study on the Properties and Pore Structure of Geopolymer Foam Concrete Incorporating Lead–Zinc Tailings
Study on the Properties and Pore Structure of Geopolymer Foam Concrete Incorporating Lead–Zinc Tailings Open
Geopolymer foam concrete (GFC) is a green, lightweight material produced by introducing bubbles into the geopolymer slurry. The raw materials for GFC are primarily silicon–aluminum-rich minerals or solid waste. Lead–zinc tailings (LZTs), a…
View article: Preparation of Lightweight and High-Strength Ceramsite from High-Silicon Lead-Zinc Tailings: A Sustainable Method for Waste Recycling
Preparation of Lightweight and High-Strength Ceramsite from High-Silicon Lead-Zinc Tailings: A Sustainable Method for Waste Recycling Open
This study proposes a sustainable method to convert high-silicon lead-zinc tailings (HS-LZT) into lightweight and high-strength ceramsite, aiming to address the issues of solid waste management and resource efficiency by using HS-LZT and k…
View article: CHANG-ES
CHANG-ES Open
Context. Understanding the configuration of galactic magnetic fields is essential for interpreting feedback processes in galaxies. Despite their importance, the exact structure of these fields, particularly in galactic halos, remains uncle…
View article: Antiferromagnetic semimetal terahertz photodetectors enhanced through weak localization
Antiferromagnetic semimetal terahertz photodetectors enhanced through weak localization Open
Effective detection is critical for terahertz applications, yet it remains hindered by the unclear mechanisms that necessitate a deeper understanding of photosensitive materials with exotic physical phenomena. Here, we investigate the tera…
View article: A Study of Personalized Language Learning with AI Technology and Media Convergence
A Study of Personalized Language Learning with AI Technology and Media Convergence Open
The convergence of AI and social media opens up a whole new path for personalized language learning. Traditional classroom teaching methods often fail to meet the individual needs of today’s learners, a dilemma that is eased by AI’s intell…
View article: Phase-Transition-Driven Reconfigurable Thermoelectric Logic in Correlated Electron Systems
Phase-Transition-Driven Reconfigurable Thermoelectric Logic in Correlated Electron Systems Open
Charge density waves (CDWs), as a hallmark of strongly correlated electronic systems in low-dimensional materials, exhibit collective quantum phenomena that enable phase-coherent electronic manipulation. In this work, we demonstrate a reco…
View article: Slowing myopia progression with cylindrical annular refractive elements ( <scp>CARE</scp> ) spectacle lenses—Year 1 results from a 2‐year prospective, multi‐centre trial
Slowing myopia progression with cylindrical annular refractive elements ( <span>CARE</span> ) spectacle lenses—Year 1 results from a 2‐year prospective, multi‐centre trial Open
Purpose To evaluate the effectiveness of 12 months of spectacle lens wear incorporating cylindrical annular refractive elements (CARE) in slowing myopia progression compared to single vision (SV) spectacle wear. Methods In an ongoing 2‐yea…