Xu Zhang
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View article: Correlation analysis between EGFR gene mutation status, ALK positivity and demographic data, tumor biomarkers, radiological and pathological features in patients with lung adenocarcinoma
Correlation analysis between EGFR gene mutation status, ALK positivity and demographic data, tumor biomarkers, radiological and pathological features in patients with lung adenocarcinoma Open
Objective This study aimed to explore the relationship between EGFR mutations, ALK positivity, and demographic, tumor, radiological, and pathological characteristics in lung adenocarcinoma patients. Methods This study included 626 patients…
View article: Downregulation of PCYT2 by increased portal pressure safeguards liver regeneration after partial hepatectomy
Downregulation of PCYT2 by increased portal pressure safeguards liver regeneration after partial hepatectomy Open
View article: Correction: ALKBH5 suppresses miR-29a-3p expression, thereby exacerbating the inflammatory response associated with spinal tuberculosis
Correction: ALKBH5 suppresses miR-29a-3p expression, thereby exacerbating the inflammatory response associated with spinal tuberculosis Open
View article: Identification and functional analysis of circular RNAs in intervertebral disc lesion tissues from spinal tuberculosis patients
Identification and functional analysis of circular RNAs in intervertebral disc lesion tissues from spinal tuberculosis patients Open
Background Spinal tuberculosis (STB) is characterized by an insidious onset, nonspecific clinical manifestations, and diagnostic challenges in early stages. Circular RNAs (circRNAs), a class of stable single-stranded endogenous RNAs with c…
View article: Multidisciplinary management of concurrent small cell lung cancer and hepatocellular carcinoma: A rare case report with long-term survival
Multidisciplinary management of concurrent small cell lung cancer and hepatocellular carcinoma: A rare case report with long-term survival Open
Rationale: Coexisting small cell lung cancer (SCLC) and hepatocellular carcinoma (HCC) is extraordinarily uncommon; in elderly patients with cardiac dysfunction it demands highly individualized, cardio-conscious care. Patient concerns: A 7…
View article: Calculation of arterial oxygen saturation by skin pigment adjustment: a research survey for people of three skin colors
Calculation of arterial oxygen saturation by skin pigment adjustment: a research survey for people of three skin colors Open
Purpose Blood oxygen saturation (SaO $$_2$$ 2 ), provided by blood gas analyzers, reflects the oxygen content in the blood. SpO $$_2$$ 2 , provided by non-invasive methods, also indicates oxygen content. However, there is often a certain b…
View article: ALKBH5 suppresses miR-29a-3p expression, thereby exacerbating the inflammatory response associated with spinal tuberculosis
ALKBH5 suppresses miR-29a-3p expression, thereby exacerbating the inflammatory response associated with spinal tuberculosis Open
ALKBH5 was upregulated in both spinal tuberculosis tissues and cellular models, whereas miR-29a-3p exhibited marked downregulation. Inhibition of miR-29a-3p expression led to increased levels of tumor necrosis factor-α (TNF-α), interleukin…
View article: Acute lymphoblastic leukemia with Fusarium solani infection: a case report
Acute lymphoblastic leukemia with Fusarium solani infection: a case report Open
Background Fusarium infections are rare but life-threatening in immunocompromised patients, particularly those with acute lymphoblastic leukemia (ALL) undergoing chemotherapy. This case report describes a patient with ALL who developed mul…
View article: METTL14 mediates the m6A methylation of miR-29a-3p, thereby activating the MAP2K6 signaling pathway and exacerbating the inflammatory response associated with spinal tuberculosis
METTL14 mediates the m6A methylation of miR-29a-3p, thereby activating the MAP2K6 signaling pathway and exacerbating the inflammatory response associated with spinal tuberculosis Open
This research uncovers the crucial role of the METTL14/ miR-29a-3p/ MAP2K6 axis in spinal tuberculosis, providing experimental evidence for the utilization of non-coding RNA as molecular targets in spinal tuberculosis, providing references…
View article: ISCU-p53 axis orchestrates macrophage polarization to dictate immunotherapy response in esophageal squamous cell carcinoma
ISCU-p53 axis orchestrates macrophage polarization to dictate immunotherapy response in esophageal squamous cell carcinoma Open
Immunological heterogeneity in esophageal squamous cell carcinoma (ESCC) poses a significant challenge to the efficacy and response to immunotherapy. In this study, we used single-cell RNA sequencing to uncover substantial heterogeneity in…
View article: Mitochondrial oxidative stress inhibited Sirt3/Foxo3/PPARα pathway and aggravated copper and zinc co-deficiency-induced hepatic lipotoxicity in a fish model
Mitochondrial oxidative stress inhibited Sirt3/Foxo3/PPARα pathway and aggravated copper and zinc co-deficiency-induced hepatic lipotoxicity in a fish model Open
Copper (Cu) and zinc (Zn) are essential trace elements for terrestrial animals. Studies suggested that single dietary Cu- or Zn- deficiency lead to liver lipid deposition and cause metabolic dysfunction-associated steatotic liver disease (…
View article: Study on the stability of sodium alginate modified zein/adzuki bean seed coat polyphenol composite nanoparticles and the loading of curcumin in emulsion
Study on the stability of sodium alginate modified zein/adzuki bean seed coat polyphenol composite nanoparticles and the loading of curcumin in emulsion Open
View article: Model Test of Mechanical Response of Negative Poisson’s Ratio Anchor Cable in Rainfall-Induced Landslides
Model Test of Mechanical Response of Negative Poisson’s Ratio Anchor Cable in Rainfall-Induced Landslides Open
Rainfall-induced landslide mitigation remains a critical research focus in geotechnical engineering, particularly for safeguarding buildings and infrastructure in unstable terrain. This study investigates the stabilizing performance of slo…
View article: Innovative Developments and Future Prospects of Geo-Energy Technology in China
Innovative Developments and Future Prospects of Geo-Energy Technology in China Open
The development of geological energy in China has a long history [...]
View article: Copper-doped TiO<sub>2</sub> photocatalyst for advanced oxidation processes: reactive oxygen species generation mechanisms
Copper-doped TiO<sub>2</sub> photocatalyst for advanced oxidation processes: reactive oxygen species generation mechanisms Open
Copper-doped anatase TiO2 (Cu/TiO2) has attracted significant attention in various sustainable chemical processes, including water splitting, carbon monoxide oxidation, carbon dioxide reduction, chemical synthesis, and advanced oxidation p…
View article: Review of sEMG for Exoskeleton Robots: Motion Intention Recognition Techniques and Applications
Review of sEMG for Exoskeleton Robots: Motion Intention Recognition Techniques and Applications Open
The global aging trend is becoming increasingly severe, and the demand for life assistance and medical rehabilitation for frail and disabled elderly people is growing. As the best solution for assisting limb movement, guiding limb rehabili…
View article: A novel tantalum scaffold promoting osteoporotic osseointegration by controlled immune regulation
A novel tantalum scaffold promoting osteoporotic osseointegration by controlled immune regulation Open
Implant failure due to osteoporosis remains a significant clinical challenge that requires further investigation and resolution. The immunomodulatory properties of bone implant materials are of great significance for the regulation of bone…
View article: Mint essential oil: A natural and effective agent for controlling house dust mites
Mint essential oil: A natural and effective agent for controlling house dust mites Open
Conventional methods of house dust mite control often involve chemical pesticides, raising concerns about their potential hazards. Mint essential oil presents a natural and eco-friendly alternative for managing house dust mite infestations…
View article: Study on the Stability of Sodium Alginate Modified Zein / Adzuki Bean Seed Coat Polyphenol Composite Nanoparticles and the Loading of Curcumin in Emulsion
Study on the Stability of Sodium Alginate Modified Zein / Adzuki Bean Seed Coat Polyphenol Composite Nanoparticles and the Loading of Curcumin in Emulsion Open
View article: Electronic Structure Engineering in Amorphous Cos Y /Coo X Composite Catalysts for Boosting Oxygen Evolution Reaction
Electronic Structure Engineering in Amorphous Cos Y /Coo X Composite Catalysts for Boosting Oxygen Evolution Reaction Open
View article: Transdermal Delivery of Superoxide Dismutase Using Polymeric Microneedle Patches to Inhibit Skin Aging
Transdermal Delivery of Superoxide Dismutase Using Polymeric Microneedle Patches to Inhibit Skin Aging Open
Skin aging is characterized by a deterioration of skin quality over time resulting from physiological changes and oxidative stress (OS). Superoxide dismutase (SOD) is an effective antioxidant enzyme widely used as a food supplement and cos…
View article: The development of a dietary nutrient density educational tool and the investigation of its acceptance by Chinese residents from Henan province
The development of a dietary nutrient density educational tool and the investigation of its acceptance by Chinese residents from Henan province Open
View article: Effects of Ferulic Acid on Lipopolysaccharide-Induced Oxidative Stress and Gut Microbiota Imbalance in Linwu Ducks
Effects of Ferulic Acid on Lipopolysaccharide-Induced Oxidative Stress and Gut Microbiota Imbalance in Linwu Ducks Open
Oxidative stress is a major factor that limits the development of the poultry industry. Ferulic acid (FA) has an antioxidant effect in birds, but the mechanism is not fully understood. In this study, we stimulated oxidative stress in 28-da…
View article: Identification of hub genes and potential molecular mechanisms in MSS/MSI classifier primary colorectal cancer based on multiple datasets
Identification of hub genes and potential molecular mechanisms in MSS/MSI classifier primary colorectal cancer based on multiple datasets Open
View article: Constrained Online Recursive Source Separation Framework for Real-time Electrophysiological Signal Processing
Constrained Online Recursive Source Separation Framework for Real-time Electrophysiological Signal Processing Open
Background and Objective: Processing electrophysiological signals often requires blind source separation (BSS) due to the nature of mixing source signals. However, its complex computational demands make real-time BSS challenging. The objec…
View article: Identification of hub genes and potential molecular mechanisms in MSS/MSI classifier primary colorectal cancer based on multiple datasets
Identification of hub genes and potential molecular mechanisms in MSS/MSI classifier primary colorectal cancer based on multiple datasets Open
Objective MSI has a better prognosis than MSS in colorectal cancer patients, and the main objective of this study was to screen MSI/MSS primary colorectal cancer differentially expressed molecules by bioinformatics. Material and methods Tw…
View article: Electrochemical techniques for uranium extraction from water
Electrochemical techniques for uranium extraction from water Open
Electrochemical removal of uranium from water is an emerging topic that addresses the treatment of drinking water, remediation of contaminated sites, and mining from seawater. Electrochemical strategies compare favorably to conventional pr…
View article: Near-infrared light activated rapidly separable polymeric microneedles for transdermal biologics delivery
Near-infrared light activated rapidly separable polymeric microneedles for transdermal biologics delivery Open
Polymeric microneedles (PMNs) are an attractive transdermal drug delivery approach with minimal invasiveness and improved patient compliance. However, it is uncomfortable and inconvenient for patients to wear a PMN patch for hours or days …
View article: High-energy and high-amino acid diet enhances production performance and antioxidant capacity in yellow-feathered broilers under heat stress
High-energy and high-amino acid diet enhances production performance and antioxidant capacity in yellow-feathered broilers under heat stress Open
View article: Electrochemical Techniques for Uranium Extraction from Water
Electrochemical Techniques for Uranium Extraction from Water Open
Electrochemical removal of uranium from water is an emerging topic that addresses the treatment of drinking water, remediation of contaminated sites, and mining from seawater. Electrochemical strategies compare favorably to conventional pr…