Zachary Paxton
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View article: Validation of a Precise Impactor in a Rodent Cervical Spinal Cord Injury Hemi-Contusion Model
Validation of a Precise Impactor in a Rodent Cervical Spinal Cord Injury Hemi-Contusion Model Open
Background: Cervical spinal cord injuries (SCIs) are the most common type of human SCI. Although various animal SCI contusion models have been developed to mirror human pathology, few have described cervical-level injuries. This study aims…
View article: Amyand's hernia with perforated appendix and scrotal abscess in a premature newborn
Amyand's hernia with perforated appendix and scrotal abscess in a premature newborn Open
View article: Early investigations into improving bowel and bladder function in fetal ovine myelomeningocele repair
Early investigations into improving bowel and bladder function in fetal ovine myelomeningocele repair Open
Ovine fetal MMC repair augmented with PMSC-ECM results in near-normal bowel and bladder function. Further work is needed to evaluate these outcomes in human patients.
View article: Table of Contents
Table of Contents Open
View article: Long-term safety evaluation of placental mesenchymal stromal cells for in utero repair of myelomeningocele in a novel ovine model
Long-term safety evaluation of placental mesenchymal stromal cells for in utero repair of myelomeningocele in a novel ovine model Open
View article: Placental Mesenchymal Stromal Cells: Preclinical Safety Evaluation for Fetal Myelomeningocele Repair
Placental Mesenchymal Stromal Cells: Preclinical Safety Evaluation for Fetal Myelomeningocele Repair Open
View article: Efficacy of clinical-grade human placental mesenchymal stromal cells in fetal ovine myelomeningocele repair
Efficacy of clinical-grade human placental mesenchymal stromal cells in fetal ovine myelomeningocele repair Open
View article: 154 Placental MSCs for in utero myelomeningocele repair do not present additional risk for pregnant ewes
154 Placental MSCs for in utero myelomeningocele repair do not present additional risk for pregnant ewes Open
View article: Placental Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Myelin Regeneration in an Animal Model of Multiple Sclerosis
Placental Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Myelin Regeneration in an Animal Model of Multiple Sclerosis Open
Mesenchymal stem/stromal cells (MSCs) display potent immunomodulatory and regenerative capabilities through the secretion of bioactive factors, such as proteins, cytokines, chemokines as well as the release of extracellular vesicles (EVs).…
View article: In utero treatment of myelomeningocele with placental mesenchymal stromal cells — Selection of an optimal cell line in preparation for clinical trials
In utero treatment of myelomeningocele with placental mesenchymal stromal cells — Selection of an optimal cell line in preparation for clinical trials Open
View article: Spinal Angulation: A Limitation of the Fetal Lamb Model of Myelomeningocele
Spinal Angulation: A Limitation of the Fetal Lamb Model of Myelomeningocele Open
Introduction: The surgically induced fetal lamb model is the most commonly used large animal model of myelomeningocele (MMC) but is subject to variation due to surgical technique during defect creation. Material and Met…