Zahid Bashir
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View article: 578 A First-in-human phase I/IIa dose escalation trial evaluating the safety and preliminary efficacy of LEU011, a novel CAR-T, in subjects with relapsed/refractory solid tumors (AERIAL)
578 A First-in-human phase I/IIa dose escalation trial evaluating the safety and preliminary efficacy of LEU011, a novel CAR-T, in subjects with relapsed/refractory solid tumors (AERIAL) Open
View article: 543 VIDAR-1: a phase 1/2a master protocol for open-label, multi-centre, single-arm, first-in-human clinical studies of autologous TCR-T therapy targeting mutant KRAS in metastatic or locally advanced PDAC
543 VIDAR-1: a phase 1/2a master protocol for open-label, multi-centre, single-arm, first-in-human clinical studies of autologous TCR-T therapy targeting mutant KRAS in metastatic or locally advanced PDAC Open
View article: Canavan disease: emerging cases in non-Ashkenazi population
Canavan disease: emerging cases in non-Ashkenazi population Open
View article: NON-INTEREST FINANCIAL INSTITUTIONS IN TACKLING FINANCIAL EXCLUSION AND ECONOMIC DEVELOPMENT
NON-INTEREST FINANCIAL INSTITUTIONS IN TACKLING FINANCIAL EXCLUSION AND ECONOMIC DEVELOPMENT Open
This study aims to provide a solution to poverty and financial exclusion in North-East (BAY) states using non-interest financial institutions and financial technology (Fintech) to enhance economic development and accelerate the financial s…
View article: Maintenance olaparib monotherapy in patients with platinum-sensitive relapsed ovarian cancer without a germline BRCA1 and/or BRCA2 mutation: Final overall survival results from the OPINION trial
Maintenance olaparib monotherapy in patients with platinum-sensitive relapsed ovarian cancer without a germline BRCA1 and/or BRCA2 mutation: Final overall survival results from the OPINION trial Open
View article: Micro-nutrient sufficiency in mothers and babies: management of deficiencies while avoiding overload during pregnancy
Micro-nutrient sufficiency in mothers and babies: management of deficiencies while avoiding overload during pregnancy Open
Pregnancy is a period characterized by extensive physiological changes in both the mother and fetus. During this period, the nutritional status of the mother has a profound and irreversible impact on her health and the growth and developme…
View article: Overall survival with maintenance olaparib in platinum-sensitive relapsed ovarian cancer by somatic or germline BRCA and homologous recombination repair mutation status
Overall survival with maintenance olaparib in platinum-sensitive relapsed ovarian cancer by somatic or germline BRCA and homologous recombination repair mutation status Open
View article: The role of trust in financial robo-advisory adoption: A case of young retail investors in Pakistan
The role of trust in financial robo-advisory adoption: A case of young retail investors in Pakistan Open
This study examines the trust of retail investors in financial robo-advisory (FRA) services and their intent to adopt them in Pakistan. It also explores the moderating role of age on trust propensity and initial trust. Data were collected …
View article: Assessing the Impact of Organizational Readiness and Digital Financial Innovation on Financial Resilience: Evidence from Banking Sector of an Emerging Economy
Assessing the Impact of Organizational Readiness and Digital Financial Innovation on Financial Resilience: Evidence from Banking Sector of an Emerging Economy Open
Commercial banks in Pakistan are confronted by increasing market volatility, regulatory challenges, and rapid technological changes. Each of these is a financial stability and adaptiveness forgoer, and further explanation is needed regardi…
View article: Roadmap to Sustainable Finance: A Bibliometric Analysis of Socially Responsible Investment in Financial Institutions
Roadmap to Sustainable Finance: A Bibliometric Analysis of Socially Responsible Investment in Financial Institutions Open
The current study aims to examine the role of Socially Responsible Investment (SRI) in Financial Institutions (FIs), as well as research gaps and future directions. A bibliometric analysis is conducted using the Elsevier Scopus database an…
View article: Dynamics of Team-Based Learning in Molecular Biology: Insights and Reflections From Undergraduate Medical Students
Dynamics of Team-Based Learning in Molecular Biology: Insights and Reflections From Undergraduate Medical Students Open
The study highlights the positive effects of TBL in promoting peer-to-peer engagement, active engagement, teamwork skills, and knowledge sharing among undergraduate medical students, ultimately contributing to an effective learning experie…
View article: Role of Managerial Innovation Behavior for moderating the effect of the Dynamic Innovation Capability on Banking Performance: Evidence from Pakistan
Role of Managerial Innovation Behavior for moderating the effect of the Dynamic Innovation Capability on Banking Performance: Evidence from Pakistan Open
The current study attempts to address the role of dynamic innovation capabilities, along with innovative work behavior of managerial employees, to explain banking performance in Pakistan. Furthermore, it also examines the moderating role o…
View article: 269 Preferential targeting of HER2-expressing cancer cells by FT825/ONO-8250, an off-the-shelf iPSC-derived CAR-T cell incorporating novel synthetic mechanisms for enhanced solid tumor activity
269 Preferential targeting of HER2-expressing cancer cells by FT825/ONO-8250, an off-the-shelf iPSC-derived CAR-T cell incorporating novel synthetic mechanisms for enhanced solid tumor activity Open
View article: Frequency, Risk Factors, and Methods of Deliberate Self-Harm Observed in Medical Students and Doctors in Pakistan
Frequency, Risk Factors, and Methods of Deliberate Self-Harm Observed in Medical Students and Doctors in Pakistan Open
DSH is a critical issue among medical students and is becoming prevalent. Higher odds of DSH are associated with smoking and recreational drug use. Higher self-esteem and better social support are protective against DSH.
View article: Fintech Adoption and Financial Inclusion: Evidence from a panel of selected Developing Economies
Fintech Adoption and Financial Inclusion: Evidence from a panel of selected Developing Economies Open
View article: Boardroom Alchemy: Unravelling the Debt and Agency Costs in Manufacturing Sector of Pakistan
Boardroom Alchemy: Unravelling the Debt and Agency Costs in Manufacturing Sector of Pakistan Open
The current study aims to investigate boardroom diversity and its varying characteristics by using agency theory to examine the effect of debt and agency costs in the manufacturing sector of Pakistan. Precisely, it seeks to examine how boa…
View article: Navigating Medical Education in the COVID-19 Era: Comparative Evaluation of Undergraduate Medical Curriculum Online vs. Hybrid Model
Navigating Medical Education in the COVID-19 Era: Comparative Evaluation of Undergraduate Medical Curriculum Online vs. Hybrid Model Open
Background The evaluation of undergraduate medical curricula plays a crucial role in ensuring effectiveness and helps in continuous improvement. This study aimed to compare the context, input, process, and output of the first-year MBBS cur…
View article: Sources of uncertainty and their impact on stock prices evidence from emerging economies
Sources of uncertainty and their impact on stock prices evidence from emerging economies Open
This study investigates the short- and long-term effects of various sources of uncertainty on the share prices of key exchanges in emerging nations. The sample comprises monthly time series data from January 2017 to December 2021 for China…
View article: BTM 3566, a Novel Activator of the Mitochondrial Stress Response Induces Robust Therapeutic Responses in Diffuse Large B‐cell Lymphoma in vitro and in vivo
BTM 3566, a Novel Activator of the Mitochondrial Stress Response Induces Robust Therapeutic Responses in Diffuse Large B‐cell Lymphoma in vitro and in vivo Open
Introduction: Relapsed/refractory diffuse large B-cell lymphomas (r/r-DLBCL) are a therapeutic challenge, especially in patients not suitable for high dose chemotherapy, stem cell transplantation or patients who fail CAR-T-cell therapy. r/…
View article: The Role of Trust in Financial Robo-Advisory Adoption: A Case of Retail Investors in Pakistan
The Role of Trust in Financial Robo-Advisory Adoption: A Case of Retail Investors in Pakistan Open
View article: Institutional Herding and Equity Returns: Do Institutions Derive Valuable Information from their Network?
Institutional Herding and Equity Returns: Do Institutions Derive Valuable Information from their Network? Open
View article: Behavioral biases, financial literacy, and investment decision: A case of individual investors in Pakistan
Behavioral biases, financial literacy, and investment decision: A case of individual investors in Pakistan Open
This research dives into the interesting world of investment choices and analyses the influence that behavioural biases and financial literacy play in the process. The study uncovers the direct impact of behavioural biases such as anchorin…
View article: Cultural Barriers in Women Empowerment in the Rural Areas of Faisalabad
Cultural Barriers in Women Empowerment in the Rural Areas of Faisalabad Open
The ability of women to participate in sociocultural, economic, and political life is crucial for their ability to maintain their homes, grow as individuals, and support their economies. The purpose of this study was to examine cultural co…
View article: 2022-RA-1290-ESGO Maintenance olaparib rechallenge in patients with ovarian cancer previously treated with a PARP inhibitor: detailed safety results from the Phase IIIb OReO/ENGOT-ov38 trial
2022-RA-1290-ESGO Maintenance olaparib rechallenge in patients with ovarian cancer previously treated with a PARP inhibitor: detailed safety results from the Phase IIIb OReO/ENGOT-ov38 trial Open
Introduction/Background OReO/ENGOT-ov38 (NCT03106987) demonstrated a statistically significant progression-free survival benefit with maintenance olaparib rechallenge versus placebo in patients with platinum-sensitive relapsed ovarian canc…
View article: EFFECTS OF AVOCADO (PERSEA AMERICANA) AQUEOUS SEED EXTRACT ON GROSS FEATURES OF LIVER AND HEPATOCYTE SIZE IN ISONIAZID AFFECTED ALBINO RATS
EFFECTS OF AVOCADO (PERSEA AMERICANA) AQUEOUS SEED EXTRACT ON GROSS FEATURES OF LIVER AND HEPATOCYTE SIZE IN ISONIAZID AFFECTED ALBINO RATS Open
Background: Isoniazid (INH) has been associated with severe hepatotoxicity and fatal liver injury. This study aimed to observe the hepatoprotective effects of concomitant use of avocado aqueous seed extract on the gross features of liver a…
View article: Ultrasound Findings in Dengue Fever: A Single Center Study
Ultrasound Findings in Dengue Fever: A Single Center Study Open
Dengue fever is the most quickly spreading and transmitted mosquito bite disease, with an annual incidence of around 50 million people. Plasma leakage during dengue fever results in the development of serious consequences. Objective: To de…
View article: How do dynamic financing decisions explain the behavior of dividend payout policies?
How do dynamic financing decisions explain the behavior of dividend payout policies? Open
The study investigates the factors that influence dividend payout policy in public Pakistani manufacturing companies throughout the timeframe 2010-20. Pooled OLS technique was used for regression purposes, as the majority of companies do n…
View article: Variations in Symptomatology of Migraine Among Local Population of Pakistan
Variations in Symptomatology of Migraine Among Local Population of Pakistan Open
Introduction: Migraine is considered one of the most disabling neurological disorders worldwide. Migraine has recently been shown to effect population with a severe cascade of symptoms. With still a huge gap in understanding of pathogenesi…
View article: Predicting Survival for Chimeric Antigen Receptor T-Cell Therapy: A Validation of Survival Models Using Follow-Up Data From ZUMA-1
Predicting Survival for Chimeric Antigen Receptor T-Cell Therapy: A Validation of Survival Models Using Follow-Up Data From ZUMA-1 Open
Where a plateau in the survival curve is clinically plausible, cure-based models may be helpful in making accurate predictions based on immature data. The ability to reliably extrapolate from maturing data may reduce delays in patient acce…
View article: Role of Organizational Capital at Different Phases of Business’s life Cycle A study of PSX Companies
Role of Organizational Capital at Different Phases of Business’s life Cycle A study of PSX Companies Open
The goal of this study was to examine the association between Business Life Cycle phases and organizational capital using PSX index companies. Mainly, the study investigates the relationship of organizational capital phases during differen…