Zailin Yang
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View article: VFM-SSL-BMADCC-Framework: vision foundation model and self-supervised learning based automated framework for differential cell counts on whole-slide bone marrow aspirate smears
VFM-SSL-BMADCC-Framework: vision foundation model and self-supervised learning based automated framework for differential cell counts on whole-slide bone marrow aspirate smears Open
Background Differential cell counts (DCCs) on bone marrow aspirate (BMA) smear is a critical step in the diagnosis and treatment of blood and bone marrow diseases. However, manual counts relies on the experience of pathologists and is very…
View article: Seismic Analysis of Semi-rigid Frames using Skeleton Joints
Seismic Analysis of Semi-rigid Frames using Skeleton Joints Open
This study proposes a new type of flange-widened bone-type semi-rigid frame node, and takes a 4-story frame as an example, uses the finite element software Abaqus to analyze its seismic performance under different seismic waves, and compar…
View article: A national, multicenter, retrospective study of human immunodeficiency virus infection-associated lymphoma in China
A national, multicenter, retrospective study of human immunodeficiency virus infection-associated lymphoma in China Open
View article: Characteristics of a new UT-type prefabricated joint for rectangular steel tubes under combined axial-moment loading
Characteristics of a new UT-type prefabricated joint for rectangular steel tubes under combined axial-moment loading Open
This study proposes a UT-type prefabricated joint incorporating adjustable sleeves (±5 mm tolerance) and an energy-dissipating segment to address the practical demands for construction tolerance management and plasticity assurance. Through…
View article: Clinical Potential of Copy Number Aberration as a Diagnostic and Prognostic Biomarker in Lymphoma
Clinical Potential of Copy Number Aberration as a Diagnostic and Prognostic Biomarker in Lymphoma Open
Lymphoma is a highly heterogeneous malignancy, demanding accurate and precise diagnosis to guide the selection of the appropriate treatment for optimal outcome. Copy number aberration (CNA) has been suggested to play an important role in t…
View article: Viral oncogenesis in cancer: from mechanisms to therapeutics
Viral oncogenesis in cancer: from mechanisms to therapeutics Open
The year 2024 marks the 60th anniversary of the discovery of the Epstein-Barr virus (EBV), the first virus confirmed to cause human cancer. Viral infections significantly contribute to the global cancer burden, with seven known Group 1 onc…
View article: Serum β2-microglobulin level is associated with the survival of HIV-associated diffuse large B-cell lymphoma: a retrospective study from China
Serum β2-microglobulin level is associated with the survival of HIV-associated diffuse large B-cell lymphoma: a retrospective study from China Open
View article: Analysis of the dynamic stress response of SH wave propagation in functional gradient materials
Analysis of the dynamic stress response of SH wave propagation in functional gradient materials Open
View article: Acute Myeloid Leukemia with NUP98: : LNP1 Fusion Mimicking Chronic Myeloid Leukemia
Acute Myeloid Leukemia with NUP98: : LNP1 Fusion Mimicking Chronic Myeloid Leukemia Open
View article: Impact of maternal COVID-19 infection on offspring immunity and maternal-fetal outcomes at different pregnancy stages: a cohort study
Impact of maternal COVID-19 infection on offspring immunity and maternal-fetal outcomes at different pregnancy stages: a cohort study Open
No adverse outcomes were observed in mothers or infants at any stage of maternal SARS-CoV-2 infection. Antibodies in umbilical cord blood and breast milk may offer passive immunity to newborns for 1-3 months. Reinfection during pregnancy m…
View article: The single-cell immune landscape of HIV-associated aggressive B-cell lymphoma
The single-cell immune landscape of HIV-associated aggressive B-cell lymphoma Open
Our findings clearly indicate that HAL differs significantly from non-HAL, ranging from malignant B cells to the immune microenvironment. This study provides a comprehensive single-cell atlas of HIV-associated aggressive B-cell lymphomas, …
View article: The CD4/CD8 ratio is associated with T lymphocyte functions in long-term virally suppressed patients with HIV
The CD4/CD8 ratio is associated with T lymphocyte functions in long-term virally suppressed patients with HIV Open
Objective Long-term management of people living with HIV (PLWHs) often relies on CD4 + T cell counts for assessing immune recovery, yet a single metric offers limited information. This study aimed to explore the association between the CD4…
View article: Dynamic behavior and residual performance of CFDSTCs under coupled collision and blast loads
Dynamic behavior and residual performance of CFDSTCs under coupled collision and blast loads Open
Bridges can suffer partial or even total collapse when bridge piers, as crucial load-bearing bridge components, are hit by vehicles or ships. Concrete-filled double-skin steel tubular columns (CFDSTCs) offer high bearing capacity and good …
View article: Numerical simulation of hollow-core FRP-concrete-steel column subjected to the combined collision and blast loads
Numerical simulation of hollow-core FRP-concrete-steel column subjected to the combined collision and blast loads Open
Hollow-core fiber-reinforced polymer-concrete-steel (HC-FCS) column is emerging as a viable option as the bridge pier that has excellent structural performance and superior corrosion resistance. Although the HC-FCS column exhibits superb r…
View article: Polatuzumab vedotin/bendamustine/rituximab (pola-BR) in R/R diffuse large B cell lymphoma with hemophagocytic lymphohistiocytosis
Polatuzumab vedotin/bendamustine/rituximab (pola-BR) in R/R diffuse large B cell lymphoma with hemophagocytic lymphohistiocytosis Open
View article: CX43-mediated mitochondrial transfer maintains stemness of KG-1a leukemia stem cells through metabolic remodeling
CX43-mediated mitochondrial transfer maintains stemness of KG-1a leukemia stem cells through metabolic remodeling Open
CX43-mediated mitochondrial transfer from BMSCs to KG-1a enhances LSCs adhesion, proliferation, clonogenicity, and metabolic reprogramming. CX43 emerges as a potential therapeutic target for AML by sustaining LSCs stemness through metaboli…
View article: Fabrication of Hydroxyl Modified Hollow Glass Microsphere Composite Isocyanate‐Based Polyimide Foam and Optimization Strategy Based on Different Bonding Mechanisms
Fabrication of Hydroxyl Modified Hollow Glass Microsphere Composite Isocyanate‐Based Polyimide Foam and Optimization Strategy Based on Different Bonding Mechanisms Open
In this study, the hydroxyl modified hollow glass microsphere (HM‐HGM) is added to different foaming slurries of isocyanate‐based polyimide foam (IBPIF) at varying ratios, and different bonding effects are formed to optimize the dispersion…
View article: Risk factors for COVID-19 pneumonia in patients with hematological malignancies: a multi-center, prospective study in China
Risk factors for COVID-19 pneumonia in patients with hematological malignancies: a multi-center, prospective study in China Open
Purpose We aimed to investigate risk factors for COVID-19 pneumonia in patients with hematological malignancies (HM) after Omicron infection. Methods Data from a registered multi-center, prospective, observational study (ChiCTR2300071830) …
View article: Development and validation of machine learning-based prediction model for severe pneumonia: A multicenter cohort study
Development and validation of machine learning-based prediction model for severe pneumonia: A multicenter cohort study Open
View article: Increased SARS-CoV-2 reinfection frequency, attenuated severity, and risk factor analysis in patients with hematological malignancies
Increased SARS-CoV-2 reinfection frequency, attenuated severity, and risk factor analysis in patients with hematological malignancies Open
View article: Numerical simulation and experimental study on forming of pentaprism directional MEFP
Numerical simulation and experimental study on forming of pentaprism directional MEFP Open
Explosively formed projectile (EFP) has the advantages of high flight speed, high burst height, insensitivity to initial velocity, etc. To study the forming performance of multiple explosively formed projectile (MEFP) and to analyze the fa…
View article: Cytoplasmic TP53INP2 acts as an apoptosis partner in TRAIL treatment: the synergistic effect of TRAIL with venetoclax in TP53INP2-positive acute myeloid leukemia
Cytoplasmic TP53INP2 acts as an apoptosis partner in TRAIL treatment: the synergistic effect of TRAIL with venetoclax in TP53INP2-positive acute myeloid leukemia Open
Background Acute myeloid leukemia (AML) is a hematopoietic malignancy with poor outcomes, especially in older AML patients. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is considered a promising anticancer drug because i…
View article: The role of KLRG1: a novel biomarker and new therapeutic target
The role of KLRG1: a novel biomarker and new therapeutic target Open
Killer cell lectin-like receptor G1 (KLRG1) is an immune checkpoint receptor expressed predominantly in NK and T-cell subsets that downregulates the activation and proliferation of immune cells and participates in cell-mediated immune resp…
View article: Ectopic pleural thymoma with T-cell lymphocytosis and bone metastasis: a case report
Ectopic pleural thymoma with T-cell lymphocytosis and bone metastasis: a case report Open
View article: The development of a prediction model based on random survival forest for the prognosis of non- Hodgkin lymphoma: A prospective cohort study in China
The development of a prediction model based on random survival forest for the prognosis of non- Hodgkin lymphoma: A prospective cohort study in China Open
View article: A novel signature incorporating genes related to lipid metabolism and immune for prognostic and functional prediction of breast cancer
A novel signature incorporating genes related to lipid metabolism and immune for prognostic and functional prediction of breast cancer Open
A unique predictive signature model could effectively predict the prognosis of breast cancer, which can not only achieve survival prediction, but also screen out key genes with important functional mechanisms to guide clinical drug experim…
View article: A Case of Lymphoplasmacytic Cell Lymphoma Characterized by Marked Nuclear Fission and Brain Gyrus Nuclei of Lymphocytes
A Case of Lymphoplasmacytic Cell Lymphoma Characterized by Marked Nuclear Fission and Brain Gyrus Nuclei of Lymphocytes Open
A 67-year-old male was admitted to the hospital due to fatigue and thrombocytopenia. Peripheral blood cells analysis showed the white blood cells count of 2.99 × 109 /L, red blood cell (RBC) count of 2.08 × 1012/L, platelet count of 15 × 1…
View article: Study on wave motion of lining structures embedded in modulus inhomogeneous medium via complex function
Study on wave motion of lining structures embedded in modulus inhomogeneous medium via complex function Open
The task of this work is to study the scattering of SH waves by homogeneous lining structures in unbounded inhomogeneous medium. The shear modulus is assumed to be a function of coordinates (x,y). A two-dimensional scattering model is esta…
View article: An Analytical Solution for the Scattering of Sh Waves by Asymmetric Triangular Protrusions on Material Surfaces
An Analytical Solution for the Scattering of Sh Waves by Asymmetric Triangular Protrusions on Material Surfaces Open
View article: Scattering of Sh Waves by Elliptical Cavity and Type-Iii Crack in Deep Anisotropic Geology
Scattering of Sh Waves by Elliptical Cavity and Type-Iii Crack in Deep Anisotropic Geology Open