Zaozao Huang
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View article: Advances in immunotherapy and targeted therapy for pancreatic cancer
Advances in immunotherapy and targeted therapy for pancreatic cancer Open
Pancreatic cancer remains one of the most challenging malignancies to treat, with a poor prognosis and limited therapeutic options. Despite the success of immunotherapy and targeted therapies for other cancers, these approaches have not ye…
View article: In vivo study of the effect of anlotinib on the stemness of the lenvatinib-resistant hepatocellular carcinoma cells and the underlying mechanisms
In vivo study of the effect of anlotinib on the stemness of the lenvatinib-resistant hepatocellular carcinoma cells and the underlying mechanisms Open
Background In vivo experiments were conducted to examine the effects of the targeted drug anlotinib on the stemness of hepatocellular carcinoma (HCC) cells and lenvatinib-resistant liver cancer cells and to explore the underlying molecular…
View article: Hypoxia-inducible factor-2α and its missense mutations: potential role in HCC diagnosis, progression, and prognosis and underlying mechanism
Hypoxia-inducible factor-2α and its missense mutations: potential role in HCC diagnosis, progression, and prognosis and underlying mechanism Open
Objective This study aims to gain further the potential mechanisms of HIF-2α in tumor progression and tumorigenesis. Methods Mined The Cancer Genome Atlas (TCGA) dataset. In total, 421 participants were enrolled in the TCGAHepatocellular C…
View article: Prognostic role of plasma levels of γ-glutamyl transpeptidase in patients with advanced gastric cancer treated with anti-PD-1 immunotherapy*
Prognostic role of plasma levels of γ-glutamyl transpeptidase in patients with advanced gastric cancer treated with anti-PD-1 immunotherapy* Open
Objective Antibodies targeting programmed cell death protein 1 (PD-1) have become the mainstay of treatment for chemotherapy-refractory gastric cancer, characterized by high levels of programmed cell death ligand-1 (PDL-1) expression. Howe…
View article: Altered Fecal Microbiota Composition in Older Adults With Frailty
Altered Fecal Microbiota Composition in Older Adults With Frailty Open
Objective Frailty is a common geriatric syndrome that is diagnosed and staged based mainly on symptoms. We aimed to evaluate frailty-related alterations of the intestinal permeability and profile fecal microbiota of healthy and frail older…
View article: Prognosis of primary hepatic lymphoma: A US population-based analysis
Prognosis of primary hepatic lymphoma: A US population-based analysis Open
View article: Prognostic evaluation of esophageal cancer patients with stages I-III
Prognostic evaluation of esophageal cancer patients with stages I-III Open
The nomogram established in this study is an effective clinical tool to predict the prognosis of stages I-III EC patients without chemotherapy.
View article: Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP‐Related Proteins via Regulation of the NF‐<i>κ</i>B Signaling Pathway
Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP‐Related Proteins via Regulation of the NF‐<i>κ</i>B Signaling Pathway Open
Objective . We aimed to investigate whether apatinib has an inhibitory effect on the invasion and metastasis of liver cancer in vitro. Methods . The anti‐invasion and antimetastasis effects of apatinib in HepG2, Hep3B,Huh7 and SMMC‐7721 li…
View article: Integrative Analysis of Siglec-15 mRNA in Human Cancers Based on Data Mining
Integrative Analysis of Siglec-15 mRNA in Human Cancers Based on Data Mining Open
Objective: Cancer is expected to be the leading cause of death worldwide within the 21st century and is the single most important obstacle to extending life expectancy. Unfortunately, the most effective approach to combating cancers…