Zarina Arif
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View article: Glycoxidation of mammalian whole histone generates highly immunogenic aggregates: Sera of SLE patients contain autoantibodies against aggregates
Glycoxidation of mammalian whole histone generates highly immunogenic aggregates: Sera of SLE patients contain autoantibodies against aggregates Open
Non‐enzymatic glycation and oxidation of self‐proteins, causing formation and accumulation of advanced glycation end products (AGEs), have been reported in an array of pathologies, including systemic lupus erythematosus (SLE). Such modific…
View article: Review of: "Effect of Supplementation with Moringa Oleifera on Antioxidant and Oxidative Stress Biomarkers of Infertile Women: A Pilot Open-Label Case-Control Randomized Clinical Study"
Review of: "Effect of Supplementation with Moringa Oleifera on Antioxidant and Oxidative Stress Biomarkers of Infertile Women: A Pilot Open-Label Case-Control Randomized Clinical Study" Open
There is inconsistency in writing Moringa oleifera.Should be the same throughout the manuscript.Of these numbers, 40 had elevated reproductive hormones and were excluded.(Numbers should be deleted)
View article: Attenuation of hyperglycemia and amadori products by aminoguanidine in alloxan-diabetic rabbits occurs via enhancement in antioxidant defenses and control of stress
Attenuation of hyperglycemia and amadori products by aminoguanidine in alloxan-diabetic rabbits occurs via enhancement in antioxidant defenses and control of stress Open
The micro- and macro-complications in diabetes mellitus (DM) mainly arise from the damage induced by Amadori and advanced glycation end products, as well as the released free radicals. The primary goal of DM treatment is to reduce the risk…
View article: A study on hepatopathic, dyslipidemic and immunogenic properties of fructosylated-HSA-AGE and binding of autoantibodies in sera of obese and overweight patients with fructosylated-HSA-AGE
A study on hepatopathic, dyslipidemic and immunogenic properties of fructosylated-HSA-AGE and binding of autoantibodies in sera of obese and overweight patients with fructosylated-HSA-AGE Open
Over consumption of fructose may lead to obesity and dyslipidemia and cause fructosylation-induced alterations in the structure and function of proteins. The aim of this study was to investigate the role of fructosylated-HSA-AGE in the pat…
View article: Physicochemical characterization of carbamylated human serum albumin: an<i>in vitro</i>study
Physicochemical characterization of carbamylated human serum albumin: an<i>in vitro</i>study Open
Carbamylation is an ubiquitous process in which cyanate (OCN−) reacts with the N-terminal amino or ε-amino moiety and generates α-carbamyl amino acids and ε-carbamyl-lysine (homocitrulline).
View article: Role of Carbamylated Biomolecules in Human Diseases
Role of Carbamylated Biomolecules in Human Diseases Open
Carbamylation (or carbamoylation) is a non‐enzymatic modification of biomolecules mediated by cyanate, a dissociation product of urea. Proteins are more sensitive to carbamylation. Two major sites of carbamylation reaction are: N α ‐amino …
View article: Methylglyoxal produces more changes in biochemical and biophysical properties of human IgG under high glucose compared to normal glucose level
Methylglyoxal produces more changes in biochemical and biophysical properties of human IgG under high glucose compared to normal glucose level Open
Hyperglycaemia triggers increased production of methylglyoxal which can cause gross modification in proteins' structure vis-a-vis function though advanced glycation end products (AGEs). The AGEs may initiate vascular and nonvascular pathol…
View article: Non-enzymatic glucosylation induced neo-epitopes on human serum albumin: A concentration based study
Non-enzymatic glucosylation induced neo-epitopes on human serum albumin: A concentration based study Open
Hyperglycaemia induced non enzymatic glycation is accelerated in diabetic patients and aggressively involved in diabetes progression. Human serum albumin (HSA) is the most abundant protein in blood circulation. In hyperglycaemia, it underg…