Zbyněk Šplíchal
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View article: Escherichia coli from Human Wounds: Analysis of Resistance to β-Lactams and Expression of RND Efflux Pumps
Escherichia coli from Human Wounds: Analysis of Resistance to β-Lactams and Expression of RND Efflux Pumps Open
Each E. coli isolate displayed unique characteristics, differing in minimum inhibitory concentration (MIC) values, prevalence of acquired blaTEM and blaCTX-M genes, and expression of the RND-family pumps. This together…
View article: Chick chorioallantoic membrane (CAM) assay for the evaluation of the antitumor and antimetastatic activity of platinum-based drugs in association with the impact on the amino acid metabolism
Chick chorioallantoic membrane (CAM) assay for the evaluation of the antitumor and antimetastatic activity of platinum-based drugs in association with the impact on the amino acid metabolism Open
View article: Unveiling the nanotoxicological aspects of Se nanomaterials differing in size and morphology
Unveiling the nanotoxicological aspects of Se nanomaterials differing in size and morphology Open
Although the general concept of nanotechnology relies on exploitation of size-dependent properties of nanoscaled materials, the relation between the size/morphology of nanoparticles with their biological activity remains not well understoo…
View article: CCDC 1980740: Experimental Crystal Structure Determination
CCDC 1980740: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1980739: Experimental Crystal Structure Determination
CCDC 1980739: Experimental Crystal Structure Determination Open
View article: The Anti-Proliferative Activity of Coordination Compound-Based ZnO Nanoparticles as a Promising Agent Against Triple Negative Breast Cancer Cells
The Anti-Proliferative Activity of Coordination Compound-Based ZnO Nanoparticles as a Promising Agent Against Triple Negative Breast Cancer Cells Open
The crucial properties of ZnO NPs seem to be their morphology, size, and zinc content. The ZnO NPs with the most preferential values of all three properties show great promise for a future potential use in the therapy of TNBrCa.
View article: Possitively charged ferritin nanocages can deliver siRNA into cells
Possitively charged ferritin nanocages can deliver siRNA into cells Open
View article: Norepinephrine transporter-derived homing peptides enable rapid endocytosis of drug delivery nanovehicles into neuroblastoma cells
Norepinephrine transporter-derived homing peptides enable rapid endocytosis of drug delivery nanovehicles into neuroblastoma cells Open
View article: Novel vancomycin&ndash;peptide conjugate as potent antibacterial agent against vancomycin-resistant <em>Staphylococcus aureus</em>
Novel vancomycin–peptide conjugate as potent antibacterial agent against vancomycin-resistant <em>Staphylococcus aureus</em> Open
Overall, we showed that the preparation of conjugates from antibiotics and biologically active peptides could help us to overcome the limitation of the use of antibiotic in the treatment of infections caused by multidrug-resistant bacteria.
View article: The Role of Inflammatory Response in Stroke Associated Programmed Cell Death
The Role of Inflammatory Response in Stroke Associated Programmed Cell Death Open
Stroke represents devastating pathology which is associated with a high morbidity and mortality. Initial damage caused directly by the onset of stroke, primary injury, may be eclipsed by secondary injury which may have a much more devastat…
View article: Allelic variants in vitamin D receptor gene are associated with adiposity measures in the central-European population
Allelic variants in vitamin D receptor gene are associated with adiposity measures in the central-European population Open