Zhe Yang
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View article: Slit2 inhibits SRC-PI3K signaling pathway, regulates osteoclast differentiation of macrophages and reduces bone resorption
Slit2 inhibits SRC-PI3K signaling pathway, regulates osteoclast differentiation of macrophages and reduces bone resorption Open
Osteoporosis is a metabolic disorder characterized by increased bone resorption and decreased bone formation. As a well-characterized axon guidance molecule, Slit2 contributes to central nervous system regulation by modulating intracellula…
View article: The Construction of an Ecosystem for Collaborative Cooperation Between Teachers and AI Tools in the Context of Artificial Intelligence
The Construction of an Ecosystem for Collaborative Cooperation Between Teachers and AI Tools in the Context of Artificial Intelligence Open
The profound integration of AI into educational systems necessitates fundamental transformations in pedagogical roles and instructional paradigms. This study systematically examines the architecture of collaborative ecosystems between educ…
View article: ForensicHub: A Unified Benchmark & Codebase for All-Domain Fake Image Detection and Localization
ForensicHub: A Unified Benchmark & Codebase for All-Domain Fake Image Detection and Localization Open
The field of Fake Image Detection and Localization (FIDL) is highly fragmented, encompassing four domains: deepfake detection (Deepfake), image manipulation detection and localization (IMDL), artificial intelligence-generated image detecti…
View article: Structure of the SMYD2-PARP1 Complex Reveals Both Productive and Allosteric Modes of Peptide Binding
Structure of the SMYD2-PARP1 Complex Reveals Both Productive and Allosteric Modes of Peptide Binding Open
Allosteric regulation allows proteins to dynamically respond to environmental cues by modulating activity at sites away from the catalytic center. Despite its importance, the SET-domain protein lysine methyltransferase superfamily has been…
View article: Ideal: Independent Domain Embedding Augmentation Learning
Ideal: Independent Domain Embedding Augmentation Learning Open
View article: SMYD2 Regulates Vascular Smooth Muscle Cell Phenotypic Switching and Intimal Hyperplasia Via Interaction with Myocardin
SMYD2 Regulates Vascular Smooth Muscle Cell Phenotypic Switching and Intimal Hyperplasia Via Interaction with Myocardin Open
View article: Structural analysis, virtual screening and molecular simulation to identify potential inhibitors targeting 2'-O-ribose methyltransferase of SARS-CoV-2 coronavirus
Structural analysis, virtual screening and molecular simulation to identify potential inhibitors targeting 2'-O-ribose methyltransferase of SARS-CoV-2 coronavirus Open
SARS-CoV-2, an emerging coronavirus, has spread rapidly around the world, resulting in over ten million cases and more than half a million deaths as of July 1, 2020. Effective treatments and vaccines for SARS-CoV-2 infection do not current…
View article: Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF
Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF Open
View article: Emerging role of cystic fibrosis transmembrane conductance regulator - an epithelial chloride channel in gastrointestinal cancers
Emerging role of cystic fibrosis transmembrane conductance regulator - an epithelial chloride channel in gastrointestinal cancers Open
Cystic fibrosis transmembrane conductance regulator (CFTR), a glycoprotein with 1480 amino acids, has been well established as a chloride channel mainly expressed in the epithelial cells of various tissues and organs such as lungs, sweat g…