Zefeng Cai
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View article: Relationship between nontraditional lipid parameters and the risk of type 2 diabetes in individuals recovered from dyslipidemia: a cohort study
Relationship between nontraditional lipid parameters and the risk of type 2 diabetes in individuals recovered from dyslipidemia: a cohort study Open
Aims/Introduction Lipid profiles are essential for assessing type 2 diabetes (T2D) risk, but individuals who recover from dyslipidemia are often overlooked, leaving their residual risk unclear. This study aimed to evaluate T2D risk in indi…
View article: Association between triglyceride-glucose index and the risk of cardiometabolic diseases in metabolically healthy obese individuals: a prospective cohort study
Association between triglyceride-glucose index and the risk of cardiometabolic diseases in metabolically healthy obese individuals: a prospective cohort study Open
Background Metabolically healthy obese (MHO) individuals meet the criteria for obesity with normal blood glucose and lipid metabolism parameters, absence of hypertension, and no concurrent cardiovascular diseases. However, the association …
View article: Worldwide burden of liver cancer across middle-aged and elderly people, 1990-2021: a decomposition, cross-country inequality and frontier analysis
Worldwide burden of liver cancer across middle-aged and elderly people, 1990-2021: a decomposition, cross-country inequality and frontier analysis Open
Objective Liver cancer is a significant contributor to the global disease burden. we first provide estimates of the worldwide burden of liver cancer from 2000 to 2021 in middle-aged and elderly people with decomposition, cross-country ineq…
View article: Longitudinal Impact of Metabolic Syndrome Evolution on Incident Chronic Disease Multimorbidity: A Cohort Study
Longitudinal Impact of Metabolic Syndrome Evolution on Incident Chronic Disease Multimorbidity: A Cohort Study Open
Background Metabolic syndrome (MetS) has been associated with the development of chronic diseases, including cardiovascular disease (CVD), type 2 diabetes (T2D), and chronic kidney disease (CKD). However, the association of a longitudinal …
View article: First Principles Assessment of ZnTe and CdSe as Prospective Tunnel Barriers at the InAs/Al Interface
First Principles Assessment of ZnTe and CdSe as Prospective Tunnel Barriers at the InAs/Al Interface Open
Majorana zero modes are predicted to emerge in superconductor/semiconductor interfaces, such as Al/InAs. Majorana modes could be utilized for fault tolerant topological qubits. However, their realization is hindered by materials challenges…
View article: Association between the atherogenic index of plasma trajectory and risk of heart failure among hypertensive patients: a prospective cohort study
Association between the atherogenic index of plasma trajectory and risk of heart failure among hypertensive patients: a prospective cohort study Open
Prolonged elevation of AIP in hypertensive patients is significantly associated with an increased risk of HF. This finding suggests that regular monitoring of AIP could aid in identifying individuals at a heightened risk of HF within the h…
View article: Excessive weight gain onset-age and risk of developing diabetes mellitus: a large, prospective Chinese cohort study
Excessive weight gain onset-age and risk of developing diabetes mellitus: a large, prospective Chinese cohort study Open
Background Excessive weight gain and obesity are widely accepted as risk factors for diabetes mellitus, and the age at which obesity onsets may be related to the development of cardiovascular diseases and certain cancers. Here, we aimed to…
View article: Relationship between the cumulative exposure to atherogenic index of plasma and ischemic stroke: a retrospective cohort study
Relationship between the cumulative exposure to atherogenic index of plasma and ischemic stroke: a retrospective cohort study Open
Background Atherogenic index of plasma (AIP) has been demonstrated as a surrogate marker for ischemic stroke, but there is limited evidence for the effect of long-term elevation of AIP on ischemic stroke. Therefore, we aimed to characteriz…
View article: Accumulated exposure to high non-high-density lipoprotein cholesterol increases the risk of cardiovascular diseases in hypertensive individuals: An 11-year prospective cohort study
Accumulated exposure to high non-high-density lipoprotein cholesterol increases the risk of cardiovascular diseases in hypertensive individuals: An 11-year prospective cohort study Open
A consistently high non-HDL-C concentration increases the risk of CVD in individuals with hypertension, as does prolonged exposure to a high non-HDL-C concentration. Thus, the achievement of target blood pressure and non-HDL-C concentratio…
View article: Cumulative exposure to high remnant-cholesterol concentrations increases the risk of cardiovascular disease in patients with hypertension: a prospective cohort study
Cumulative exposure to high remnant-cholesterol concentrations increases the risk of cardiovascular disease in patients with hypertension: a prospective cohort study Open
Background The relationship of cumulative remnant-cholesterol (Cum-RC) concentration with the risk of cardiovascular disease (CVD) in patients with hypertension remains unclear. Methods We studied data for 28,698 individuals for whom three…
View article: Age-dependent changes in the risk of weight gain in Chinese adults: results from the Kailuan cohort study
Age-dependent changes in the risk of weight gain in Chinese adults: results from the Kailuan cohort study Open
The risk of weight gain in Chinese adults is age dependent, and clear public healthcare messaging is needed for young adults who are at the highest risk of weight gain.
View article: Individual and combined contributions of non-high-density lipoprotein cholesterol and brachial-ankle pulse wave velocity to cardiovascular disease risk: Results of a prospective study using the Kailuan cohort
Individual and combined contributions of non-high-density lipoprotein cholesterol and brachial-ankle pulse wave velocity to cardiovascular disease risk: Results of a prospective study using the Kailuan cohort Open
Objective We aimed to characterize the relationship of a combination of circulating non-high-density lipoprotein-cholesterol (non-HDL-C) concentration and brachial-ankle pulse wave velocity (baPWV) with cardiovascular disease (CVD). Method…
View article: The effect of acute aerobic exercise on arterial stiffness in individuals with different body fat percentages: A cross-sectional study
The effect of acute aerobic exercise on arterial stiffness in individuals with different body fat percentages: A cross-sectional study Open
Background Body fat percentage were positively correlated with arterial stiffness, but the acute change in arterial stiffness after aerobic exercise in individuals with different body fat percentages remains unclear. This study was aimed t…
View article: Visit-to-visit variability in triglyceride-glucose index and diabetes: A 9-year prospective study in the Kailuan Study
Visit-to-visit variability in triglyceride-glucose index and diabetes: A 9-year prospective study in the Kailuan Study Open
Instruction/Aims It is unknown whether variability in the triglyceride-glucose index (TyG-index) is associated with the risk of diabetes. Here, we sought to characterize the relationship between TyG-index variability and incident diabetes.…
View article: Effect of Aerobic Exercise on Arterial Stiffness in Individuals with Different Smoking Statuses
Effect of Aerobic Exercise on Arterial Stiffness in Individuals with Different Smoking Statuses Open
This study aimed to investigate the immediate effects of acute bout of aerobic exercise on arterial stiffness in individuals with different smoking statuses. A total of 940 male individuals (mean age of 36.82±7.76 years) in the Kailuan stu…
View article: Association of Cardiovascular Health Score Trajectory With Incident Myocardial Infarction in Hypertensive Patients
Association of Cardiovascular Health Score Trajectory With Incident Myocardial Infarction in Hypertensive Patients Open
Background: The association between changes in cardiovascular health score (CHS) over time and myocardial infarction (MI) risk in hypertensive patients remains unclear. Method: This was a prospective study comprising 17 374 hypertensive pa…
View article: Visit-to-visit SBP variability and risk of atrial fibrillation in middle-aged and older populations
Visit-to-visit SBP variability and risk of atrial fibrillation in middle-aged and older populations Open
Objective: We sought to examine the relationship between visit-to-visit variability of SBP and incident atrial fibrillation in middle-aged and older population. Methods: This prospective cohort study included 26 999 participants aged 50 ye…
View article: Triglyceride-glucose index trajectory and stroke incidence in patients with hypertension: a prospective cohort study
Triglyceride-glucose index trajectory and stroke incidence in patients with hypertension: a prospective cohort study Open
Background It has been suggested that the baseline triglyceride-glucose (TyG) index, a simple surrogate measure for insulin resistance, is significantly associated with the occurrence of stroke. Nevertheless, the impact of longitudinal pat…
View article: Changes in Impaired Fasting Glucose and Borderline High Low-Density Lipoprotein-Cholesterol Status Alter the Risk of Cardiovascular Disease: A 9-Year Prospective Cohort Study
Changes in Impaired Fasting Glucose and Borderline High Low-Density Lipoprotein-Cholesterol Status Alter the Risk of Cardiovascular Disease: A 9-Year Prospective Cohort Study Open
Background We aimed to characterize the relationships of the changes in impaired fasting glucose (IFG) and borderline high low-density lipoprotein-cholesterol (LDL-C) status with cardiovascular disease (CVD). Methods A total of 36,537 part…
View article: Relationship of cumulative exposure to the triglyceride-glucose index with ischemic stroke: a 9-year prospective study in the Kailuan cohort
Relationship of cumulative exposure to the triglyceride-glucose index with ischemic stroke: a 9-year prospective study in the Kailuan cohort Open
Background A single measurement of the triglyceride-glucose (TyG) index, a simple and reliable surrogate marker of insulin resistance, is associated with ischemic stroke. However, evidence for an effect of a long-term elevation in TyG inde…
View article: Association of Age of Metabolic Syndrome Onset With Cardiovascular Diseases: The Kailuan Study
Association of Age of Metabolic Syndrome Onset With Cardiovascular Diseases: The Kailuan Study Open
Background Metabolic syndrome (MetS) is associated with an increased risk of incident cardiovascular diseases (CVD), but the association between the new-onset MetS at different ages and the CVD risk remain unclear. Methods This was a prosp…
View article: Association between age at onset of overweight and risk of hypertension across adulthood
Association between age at onset of overweight and risk of hypertension across adulthood Open
Objective The aim of this study was to examine the association between age at onset of overweight and incident hypertension. Methods We analysed 4742 participants with new-onset overweight from the Kailuan study between 2006 and 2015 and a…
View article: Controlling and probing heat generation in an optical heater system
Controlling and probing heat generation in an optical heater system Open
Understanding how plasmonic nanostructures generate heat upon exposure to light, and thus increase the local temperature of the surrounding medium is important for many applications. Reliable temperature manipulation requires analyzing the…
View article: Short-Term Effect of Acute Aerobic Exercise On Arterial Stiffness in People with Different Smoking Statuses
Short-Term Effect of Acute Aerobic Exercise On Arterial Stiffness in People with Different Smoking Statuses Open
Background Smoking is strongly associated with arterial stiffness. Long-term regular aerobic exercise is an effective lifestyle intervention that improve arterial stiffness in healthy young people, however, the results of research on the i…
View article: Triglyceride to high‐density lipoprotein cholesterol ratio variability and incident diabetes: A 7‐year prospective study in a Chinese population
Triglyceride to high‐density lipoprotein cholesterol ratio variability and incident diabetes: A 7‐year prospective study in a Chinese population Open
Aims/Introduction The correlation between triglyceride to high‐density lipoprotein cholesterol (TG/HDL‐C) ratio variability and incident diabetes has not been fully elucidated. We aimed to characterize the relationship between TG/HDL‐C rat…