Zohreh Sharifi
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View article: Solvent-dependent variation in phenolic profiles, antioxidant and antibacterial activities across wild populations of Allium jesdianum
Solvent-dependent variation in phenolic profiles, antioxidant and antibacterial activities across wild populations of Allium jesdianum Open
View article: In Silico Synthesis of HSV-2 Positive Control Using Polymerase Cycling Assembly
In Silico Synthesis of HSV-2 Positive Control Using Polymerase Cycling Assembly Open
View article: Development of a TaqMan Real Time PCR Assay for Quantifying the HTLV-1 Proviral Load Using the HBZ Gene
Development of a TaqMan Real Time PCR Assay for Quantifying the HTLV-1 Proviral Load Using the HBZ Gene Open
View article: Evaluating the Effects of Imiquimod on Paths of TLRs and Inflammatory Cytokines Signaling in Infected Macrophages with Leishmania major in Vitro and in Vivo
Evaluating the Effects of Imiquimod on Paths of TLRs and Inflammatory Cytokines Signaling in Infected Macrophages with Leishmania major in Vitro and in Vivo Open
Background: Leishmania major is an obligate and intracellular pathogen and the macrophages are the cell hosts for L. major. Imiquimod stimulates macrophages to secrete different cytokines via the expression of TLRs. Methods: This study was…
View article: Ten-year experience with pediatric splenic Hydatidosis: Clinical profiles, surgical outcomes, and prognostic indicators
Ten-year experience with pediatric splenic Hydatidosis: Clinical profiles, surgical outcomes, and prognostic indicators Open
Hydatidosis, caused by Echinococcus granulosus, poses significant public health challenges, particularly in endemic regions. While hepatic and pulmonary involvement are common, splenic hydatidosis in pediatric populations is rare an…
View article: Seroepidemiology and Risk Factors of Toxoplasma gondii in Iranian COVID-19 Patients: A Case-Control Study
Seroepidemiology and Risk Factors of Toxoplasma gondii in Iranian COVID-19 Patients: A Case-Control Study Open
Background: Theoretically, there is a possible association between emerging SARS‑CoV‑2 infection and parasites such as Toxoplasma gondii. We aimed to evaluate the seroepidemiology of T. gondii in COVID-19 patients and the control group as …
View article: Design and In-Silico Evaluation of Specific Primers for the HBZ Gene of HTLV-1 to Establish a Semi-Nested PCR Method
Design and In-Silico Evaluation of Specific Primers for the HBZ Gene of HTLV-1 to Establish a Semi-Nested PCR Method Open
View article: Evaluating the Risk of Hepatitis B, Hepatitis C, and Human Immunodeficiency Virus Among High-risk Deferred Blood Donors, Based on Deferral Reasons
Evaluating the Risk of Hepatitis B, Hepatitis C, and Human Immunodeficiency Virus Among High-risk Deferred Blood Donors, Based on Deferral Reasons Open
Background: Blood donor selection is a crucial stage in reducing the risk of transfusion-transmissible infections (TTIs) and ensuring the safety of blood components. The objective of this study is to evaluate the impact of each question re…
View article: Efficacy of traditional herb aqua extract of Teucrium stocksianum and its fractions against HSV-1 virus expression levels of genes (UL46 and US6)
Efficacy of traditional herb aqua extract of Teucrium stocksianum and its fractions against HSV-1 virus expression levels of genes (UL46 and US6) Open
Background and Objectives: Recently, the anti-herpetic activities of different plant species have been investigated. This study evaluated the effects of Teucrium stocksianum aqueous extract on the HSV-1 virus-infected Vero cell. Materials …
View article: The level of expression of programmed death type 1 during the natural course of hepatitis B virus infection in asymptomatic carriers of hepatitis B
The level of expression of programmed death type 1 during the natural course of hepatitis B virus infection in asymptomatic carriers of hepatitis B Open
View article: Study on genotyping and coinfection rate of human parvovirus 4 among the HTLV-I/II infected blood donors in Khorasan Razavi, Iran
Study on genotyping and coinfection rate of human parvovirus 4 among the HTLV-I/II infected blood donors in Khorasan Razavi, Iran Open
View article: Occult hepatitis B in Iranian blood donors, an overview of the challenges: A narrative review
Occult hepatitis B in Iranian blood donors, an overview of the challenges: A narrative review Open
Background Occult hepatitis B infection (OBI) is a transfusion‐transmitted infection. Although, screening the hepatitis B virus among blood donors can play an important role in increasing the health of blood products, OBI screening in bloo…
View article: New design and optimization of an in-house quantitative TaqMan Real-Time PCR-based assay for the detection and monitoring of occult hepatitis B virus (genotype A-J) infection
New design and optimization of an in-house quantitative TaqMan Real-Time PCR-based assay for the detection and monitoring of occult hepatitis B virus (genotype A-J) infection Open
The results indicate that the in-house assay is highly sensitive and specific, reproducible, and cost-benefit. Thus, it can be used to detect and quantify HBV DNA in research and clinical settings.
View article: Prevalence of occult hepatitis B virus infection among the blood donors in Golestan province: cross-sectional study
Prevalence of occult hepatitis B virus infection among the blood donors in Golestan province: cross-sectional study Open
Background and Objectives: Despite the increased sensitivity of screening tests, the HBV can be transmitted during the window period and occult hepatitis B infection. The purpose of this study was to evaluate HBV markers and prevalence of …
View article: Therapeutic and Preventive Effects of Morphine Against Leishmania Major and Evaluation the Expression of TLRs and Cytokines in Infected Macrophages in Vitro and in BALB/c Mice
Therapeutic and Preventive Effects of Morphine Against Leishmania Major and Evaluation the Expression of TLRs and Cytokines in Infected Macrophages in Vitro and in BALB/c Mice Open
Purpose: Toll-Like Receptors (TLRs) and cytokines play key roles in infection control. They also enhance phagocytosis and killing of parasites. Morphine can modify host immunity and defense against infectious diseases. Methods: In this stu…
View article: Correlation of serum microRNA-122 level with the levels of Alanine aminotransferase and HBV-DNA in Chronic HBV-infected patients
Correlation of serum microRNA-122 level with the levels of Alanine aminotransferase and HBV-DNA in Chronic HBV-infected patients Open
Background: The microRNA-122 (miR-122) is a liver-specific microRNA that can be used as a potential molecular marker for predicting liver injury. There is a positive correlation between miR-122 level in serum and hepatitis B virus (…
View article: Silybum marianum ethanolic extract: in vitro effects on protoscolices of Echinococcus granulosus G1 strain with emphasis on other Iranian medicinal plants
Silybum marianum ethanolic extract: in vitro effects on protoscolices of Echinococcus granulosus G1 strain with emphasis on other Iranian medicinal plants Open
View article: Spatio-Temporal Analysis of the Hepatitis B Prevalence in Irani-an Blood Donors from 2000 to 2016 at National and Provincial Level
Spatio-Temporal Analysis of the Hepatitis B Prevalence in Irani-an Blood Donors from 2000 to 2016 at National and Provincial Level Open
Background: High risk blood transfusions can cause a lot of financial and psychological burden to the community. The prevalence of Hepatitis B is useful for evaluating the blood products' safety and donor selection methods. We aimed to pre…
View article: Determination of Epstein-Barr virus (EBV) incidence in umbilical cord blood (UCB) and assessment of virus DNA via Real-time PCR
Determination of Epstein-Barr virus (EBV) incidence in umbilical cord blood (UCB) and assessment of virus DNA via Real-time PCR Open
Recently, some studies have evidenced the development of the post-transplant lymphoproliferative disorders (PTLD) in patients following umbilical cord blood transplantation (UCBT) resulting from the presence of the Epstein-Barr virus (EBV)…
View article: Association of TLR3 single nucleotide polymorphisms with susceptibility to HTLV-1 infection in Iranian asymptomatic blood donors
Association of TLR3 single nucleotide polymorphisms with susceptibility to HTLV-1 infection in Iranian asymptomatic blood donors Open
INTRODUCTION: The human T-lymphotropic virus type 1 (HTLV-1) has a single-stranded RNA genome and expresses specific proteins that have oncogenic potential. Approximately 15 to 20 million people worldwide have been infected by this virus. …
View article: The Effect of Composol Medium on miR-16 Expression during Platelet Storage up to Day 7 at Room Temperature.
The Effect of Composol Medium on miR-16 Expression during Platelet Storage up to Day 7 at Room Temperature. Open
Our finding supported results from previous studies that reported an increase in miR-16 expression during platelet storage. In addition, miR-16 down-regulation in Composol medium implied that Composol might be a good solution for long-term…
View article: Human Parvovirus B19 Infection Among Blood Donors in North-East of Iran
Human Parvovirus B19 Infection Among Blood Donors in North-East of Iran Open
Background: Human parvovirus B19 is a single-stranded DNA and non-enveloped virus which belongs to the Parvoviridae family. The virus spreads through respiratory secretions and perinatal blood. B19 may cause serious complications in patien…
View article: Hepatitis E Virus Infection Among Iranian Patients with Beta-Thalassemia
Hepatitis E Virus Infection Among Iranian Patients with Beta-Thalassemia Open
Background: The main transmission route of hepatitis E virus (HEV) is fecal-oral by contaminated water and food. Besides, it can be transmitted through infected blood of persons with subclinical infection. Objectives: The current study aim…
View article: Prevalence of hepatitis E virus in thalassemia patients with hepatitis C in Tehran, Iran
Prevalence of hepatitis E virus in thalassemia patients with hepatitis C in Tehran, Iran Open
Background and Objectives: HEV infection is predominantly spread via the fecal-oral route; however, due to the presence of HEV RNA in the serum of healthy blood donors, there is a possibility of the transmissibility of HEV infection throug…
View article: Association of TLR3 single nucleotide polymorphisms with susceptibility to HTLV-1 infection in Iranian asymptomatic blood donors
Association of TLR3 single nucleotide polymorphisms with susceptibility to HTLV-1 infection in Iranian asymptomatic blood donors Open
The TLR3 SNP rs3775296 was significantly associated with HTLV-1 infection and may be a protective factor against this viral infection.
View article: Association of HCV genotype with viral load among Iranian blood donors: a penalized logistic regression
Association of HCV genotype with viral load among Iranian blood donors: a penalized logistic regression Open
Association of HCV genotype with viral load among Iranian blood donors: a penalized logistic regression
View article: Genetic Variants of Nucleotide Excision Repair Pathway and Outcomes of Induction Therapy in Acute Myeloid Leukemia
Genetic Variants of Nucleotide Excision Repair Pathway and Outcomes of Induction Therapy in Acute Myeloid Leukemia Open
Aim: Acute myeloid leukemia (AML) is a heterogeneous disease in pathogenesis and response to therapy. Nucleotide excision repair (NER) pathway has a major role in the elimination of genotoxic effects of chemotherapeutic agents. We a…
View article: Evaluation of Morphine with Imiquimod as Opioid Growth Factor Receptor or Nalmefene as Opioid Blocking Drug on Leishmaniasis Caused by Leishmania major in Vitro
Evaluation of Morphine with Imiquimod as Opioid Growth Factor Receptor or Nalmefene as Opioid Blocking Drug on Leishmaniasis Caused by Leishmania major in Vitro Open
Background: In this research, the effect of morphine on promastigotes and amastigotes of Leishmania major has been investigated in the presence of nalmefene as a blocking opioid drug and imiquimod as an opioid growth factor receptor. Metho…
View article: Evaluation of synergistic therapeutic effect of shark cartilage extract with artemisinin and glucantime on visceral leishmaniasis in BALB/c mice.
Evaluation of synergistic therapeutic effect of shark cartilage extract with artemisinin and glucantime on visceral leishmaniasis in BALB/c mice. Open
Combination therapy with shark cartilage extract as an immunomodulator can increase antileishmanial effects of antimony drugs in VL treatment.
View article: The Prevalence of Hepatitis Delta Virus in Patients with Chronic Hepatitis B and Its Association with Risk Factors
The Prevalence of Hepatitis Delta Virus in Patients with Chronic Hepatitis B and Its Association with Risk Factors Open
Background\n Hepatitis B infection is a serious health problem and two billion people worldwide are infected with the virus. The hepatitis delta virus (HDV) is a satellite virus. Hepatitis D virus infection in HBsAg carriers can be present…