Ze‐Jun Dong
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View article: MYB represses ζ-globin expression through upregulating ETO2
MYB represses ζ-globin expression through upregulating ETO2 Open
Reactivating the embryonic ζ-globin gene represents a potential therapeutic approach to ameliorate the severe clinical phenotype of α-thalassemia and sickle cell disease. The transcription factor MYB has been extensively proven to be a mas…
View article: Analysis of methylation-driven genes for predicting the prognosis of patients with oral squamous cell carcinoma
Analysis of methylation-driven genes for predicting the prognosis of patients with oral squamous cell carcinoma Open
Our findings facilitate a better understanding of molecular mechanisms of OSCC and provide potential biomarkers of early diagnosis, precision treatment and prognosis evaluation.
View article: Two new 4,6-dimethyl-3,4-dihydrochromen-2-one derivatives from <i>Craterellus odoratus</i>
Two new 4,6-dimethyl-3,4-dihydrochromen-2-one derivatives from <i>Craterellus odoratus</i> Open
Two rare types of 4,6-dimethyl-3,4-dihydrochromen-2-one derivatives, named cralactones A and B (1 and 2), were isolated from the culture broth of Craterellus odoratus. The structures of the new ones were established on…
View article: Novel Natural Oximes and Oxime Esters with a Vibralactone Backbone from the Basidiomycete <i>Boreostereum vibrans</i>
Novel Natural Oximes and Oxime Esters with a Vibralactone Backbone from the Basidiomycete <i>Boreostereum vibrans</i> Open
A variety of novel natural products with significant bioactivities are produced by the basidiomycete Boreostereum vibrans . In the present study, we describe 16 novel natural oximes and oxime esters with a vibralactone backbone, vibralacto…
View article: CCDC 1047706: Experimental Crystal Structure Determination
CCDC 1047706: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Structure-Based Optimization and Biological Evaluation of Pancreatic Lipase Inhibitors as Novel Potential Antiobesity Agents
Structure-Based Optimization and Biological Evaluation of Pancreatic Lipase Inhibitors as Novel Potential Antiobesity Agents Open
The unusual fused β-lactone vibralactone was isolated from cultures of the basidiomycete Boreostereum vibrans and has been shown to significantly inhibit pancreatic lipase. In this study, a structure-based lead optimization of vibralactone…
View article: New Diterpenes from Cultures of the Fungus Engleromyces goetzii and Their CETP Inhibitory Activity
New Diterpenes from Cultures of the Fungus Engleromyces goetzii and Their CETP Inhibitory Activity Open
View article: A Viscidane Diterpene and Polyacetylenes from Cultures of Hypsizygus marmoreus
A Viscidane Diterpene and Polyacetylenes from Cultures of Hypsizygus marmoreus Open
Investigation on the cultures of Hypsizygus marmoreus resulted in the isolation of a new viscidane diterpene, 8-oxoviscida-3,11(18)-diene-13,14,15,19-tetraol (1) and two new polyacetylenes, (E)-10-(1,1-dimethyl-2-propenyloxy)-2-decene-4,6,…
View article: Identification and Cytotoxic Activities of Two New Trichothecenes and a New Cuparane-Type Sesquiterpenoid from the Cultures of the Mushroom Engleromyces goetzii
Identification and Cytotoxic Activities of Two New Trichothecenes and a New Cuparane-Type Sesquiterpenoid from the Cultures of the Mushroom Engleromyces goetzii Open
View article: CCDC 935079: Experimental Crystal Structure Determination
CCDC 935079: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 935078: Experimental Crystal Structure Determination
CCDC 935078: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1421209: Experimental Crystal Structure Determination
CCDC 1421209: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …