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View article: Glucose and mannose analogs inhibit KSHV replication by blocking <i>N</i> ‐glycosylation and inducing the unfolded protein response
Glucose and mannose analogs inhibit KSHV replication by blocking <i>N</i> ‐glycosylation and inducing the unfolded protein response Open
Kaposi's sarcoma‐associated herpesvirus (KSHV) is the etiological agent for Kaposi's sarcoma (KS), an HIV/AIDS‐associated malignancy. Effective treatments against KS remain to be developed. The sugar analog 2‐deoxy‐ d ‐glucose (2‐DG) is an…