Hui Zhang
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View article: Fuzuloparib with or without apatinib as maintenance therapy in newly diagnosed, advanced ovarian cancer (FZOCUS‐1): A multicenter, randomized, double‐blind, placebo‐controlled phase 3 trial
Fuzuloparib with or without apatinib as maintenance therapy in newly diagnosed, advanced ovarian cancer (FZOCUS‐1): A multicenter, randomized, double‐blind, placebo‐controlled phase 3 trial Open
Although poly(adenosine diphosphate‐ribose) polymerase inhibitors (PARPis) and bevacizumab were approved as first‐line maintenance for advanced ovarian cancer (OC), evidence comparing this combination with PARPi monotherapy, especially in …
View article: Revealing the causes of inequality in rainstorm flood disaster resilience between town and rural areas in southwestern China: Based on natural and social system dimensions
Revealing the causes of inequality in rainstorm flood disaster resilience between town and rural areas in southwestern China: Based on natural and social system dimensions Open
View article: Concurrent NPM1::CCDC28A and BCR::ABL1 fusions in extramedullary blast crisis of chronic myeloid leukemia: A case report and literature review
Concurrent NPM1::CCDC28A and BCR::ABL1 fusions in extramedullary blast crisis of chronic myeloid leukemia: A case report and literature review Open
Extramedullary blast crisis (EMBC) is rare, clinically heterogeneous, and often misdiagnosed because routine histology may be inconclusive. We describe a CML-EMBC case in which targeted RNA sequencing uncovered concurrent NPM1::CCDC28A and…
View article: Management of posterior cruciate ligament injuries: an expert consensus from 17 countries
Management of posterior cruciate ligament injuries: an expert consensus from 17 countries Open
Background: Posterior cruciate ligament (PCL) injury is a relatively common musculoskeletal condition. However, there is currently a lack of consensus on decision-making, treatment and postoperative management for such injuries. Objectives…
View article: Inhaled predatory bacteria-loaded large porous microspheres to eradicate drug-resistant Pseudomonas aeruginosa from the lung
Inhaled predatory bacteria-loaded large porous microspheres to eradicate drug-resistant Pseudomonas aeruginosa from the lung Open
View article: Effects of Camellia Seed Cake Protein on the Printability, Antioxidant Activity and Digestive Performance of 3d-Printed Plant Protein Meat Analogues
Effects of Camellia Seed Cake Protein on the Printability, Antioxidant Activity and Digestive Performance of 3d-Printed Plant Protein Meat Analogues Open
View article: Extraction and Characterization of Surface-Active Compounds from Camellia Oleifera Seed Meal
Extraction and Characterization of Surface-Active Compounds from Camellia Oleifera Seed Meal Open
View article: Multiple third-generation recombinants formed by CRF55_01B and CRF07_BC in newly diagnosed HIV-1 infected patients in Shenzhen city, China
Multiple third-generation recombinants formed by CRF55_01B and CRF07_BC in newly diagnosed HIV-1 infected patients in Shenzhen city, China Open
In the evolution landscape of HIV, the coexistence of multiple subtypes has led to new, complex recombinants, posing public health challenges. CRF55_01B, first identified among MSM in Shenzhen, China, has spread rapidly across China. In th…
View article: Identification of a novel CRF01_AE/CRF07_BC (CRF163_0107) circulating recombinant form in Shenyang city, the economic center of Northeast China
Identification of a novel CRF01_AE/CRF07_BC (CRF163_0107) circulating recombinant form in Shenyang city, the economic center of Northeast China Open
View article: Association of erythrocyte fatty acid compositions with the risk of pancreatic cancer: A case–control study
Association of erythrocyte fatty acid compositions with the risk of pancreatic cancer: A case–control study Open
Pancreatic cancer (PC) is one of the most fatal malignancies, which has attracted scientists to investigate its etiology and pathogenesis. Nevertheless, the association between erythrocyte fatty acids and PC risk remains unclear. This stud…
View article: Thoughts on the research of African swine fever live-attenuated vaccines
Thoughts on the research of African swine fever live-attenuated vaccines Open
African swine fever (ASF) is a contagious and fatal disease caused by the African swine fever virus (ASFV), which can infect pigs of all breeds and ages. Most infected pigs have poor prognosis, leading to substantial economic losses for th…
View article: Ocular surface changes in moderate-to-severe acne vulgaris
Ocular surface changes in moderate-to-severe acne vulgaris Open
AIM: To investigate ocular surface disorders and tear function changes in patients with acne vulgaris and explore the potential relationship between acne vulgaris and dry eye. METHODS: This cross-sectional study included right eyes of 53 p…
View article: Effects of Different Varieties on Physicochemical Properties, Browning Characteristics, and Quality Attributes of Mume fructus (Wumei)
Effects of Different Varieties on Physicochemical Properties, Browning Characteristics, and Quality Attributes of Mume fructus (Wumei) Open
The dried Mume fructus (MF) is a special food and herbal medicine with a long history of processing and application. The browning index (BI) of Prunus mume (PM) is pivotal in determining the medicinal value and edible quality of MF. Explor…
View article: Eicosapentaenoic acid and docosahexaenoic acid suppress colonic tumorigenesis in obese mice
Eicosapentaenoic acid and docosahexaenoic acid suppress colonic tumorigenesis in obese mice Open
Chronic inflammation is a hallmark of obesity and is recognized as a cancer risk. While EPA and DHA combat inflammation associated with obesity, their effects on obesity-linked intestinal tumors requires further study. This study used the …
View article: Prevalence trends and racial-ethnic disparities of diabetes and prediabetes among children and adolescents in the United States from 2019 to 2021
Prevalence trends and racial-ethnic disparities of diabetes and prediabetes among children and adolescents in the United States from 2019 to 2021 Open
The study highlighted potential increases in diabetes prevalence from 2017 to 2021 and persistent racial/ethnic disparities. The 12-17 age subgroup exhibited significant disparities, emphasizing the need for early intervention. Targeted st…
View article: 西太平洋麦哲伦海山群Hemler、Vlinder和Il’ichev海山熔岩的成因及其形成的深部动力学机制
西太平洋麦哲伦海山群Hemler、Vlinder和Il’ichev海山熔岩的成因及其形成的深部动力学机制 Open
View article: Proteinaceous Microsphere-Based Water-in-Oil Pickering Emulsions for Preservation of Chlorella Cells
Proteinaceous Microsphere-Based Water-in-Oil Pickering Emulsions for Preservation of Chlorella Cells Open
Microalgae are highly regarded as ideal materials for the creation of liquid biofuels and have substantial potential for growth and utilization. However, traditional storage and culture methods for microalgae are plagued by challenges such…
View article: Quercetin-crosslinked chitosan nanoparticles: a potential treatment for allergic rhinitis
Quercetin-crosslinked chitosan nanoparticles: a potential treatment for allergic rhinitis Open
View article: Cost-Effectiveness of Salt Substitute and Salt Supply Restriction in Eldercare Facilities
Cost-Effectiveness of Salt Substitute and Salt Supply Restriction in Eldercare Facilities Open
Importance Salt substitution has been reported to be a cost-saving sodium reduction strategy that has not yet been replicated in different contexts. Objective To estimate the cost-effectiveness of sodium reduction strategies within the DEC…
View article: A broad host phage, CP6, for combating multidrug-resistant Campylobacter prevalent in poultry meat
A broad host phage, CP6, for combating multidrug-resistant Campylobacter prevalent in poultry meat Open
Campylobacter is a major cause of bacterial foodborne diarrhea worldwide. Consumption of raw or undercooked chicken meat contaminated with Campylobacter is the most common causative agent of human infections. Given the high prevalence of c…
View article: Quality Evaluation and Browning Control in the Multi-Stage Processing of Mume Fructus (Wumei)
Quality Evaluation and Browning Control in the Multi-Stage Processing of Mume Fructus (Wumei) Open
The dried Mume Fructus (MF), called Wumei in China, is a unique food with medicinal and edible effects. But its actual production method is outdated with low efficiency and inconsistent quality. This study systematically investigated the i…
View article: <i>PCSK9</i> genetic variants and risk of vascular and non-vascular diseases in Chinese and UK populations
<i>PCSK9</i> genetic variants and risk of vascular and non-vascular diseases in Chinese and UK populations Open
Aims Lowering low-density lipoprotein cholesterol (LDL-C) through PCSK9 inhibition represents a new therapeutic approach to preventing and treating cardiovascular disease (CVD). Phenome-wide analyses of PCSK9 genetic variants in large biob…
View article: Statistical Optimization of Tween-80-Assisted Potassium Hydroxide Pretreatment and Enzymatic Hydrolysis for Enhancing Sugar Yields from Corn Cob
Statistical Optimization of Tween-80-Assisted Potassium Hydroxide Pretreatment and Enzymatic Hydrolysis for Enhancing Sugar Yields from Corn Cob Open
With the addition of Tween 80, potassium hydroxide pretreatment and enzymatic hydrolysis were statistically optimized to maximize sugar yields from corn cob (CC). The results indicated that the sugar yields from CC could be influenced sign…
View article: Erratum to: ARID1A Inactivation Increases Expression of circ0008399 and Promotes Cisplatin Resistance in Bladder Cancer
Erratum to: ARID1A Inactivation Increases Expression of circ0008399 and Promotes Cisplatin Resistance in Bladder Cancer Open
View article: Experience with 2 years’ intervention to progressively reduce salt supply to kitchens in elderly care facilities—challenges and further research: post hoc analysis of the DECIDE-Salt randomized clinical trial
Experience with 2 years’ intervention to progressively reduce salt supply to kitchens in elderly care facilities—challenges and further research: post hoc analysis of the DECIDE-Salt randomized clinical trial Open
View article: Oleuropein and its hydrolysate from extra virgin olive oil inhibit breast cancer cells proliferation interfering with the PI3K-AKT signal pathway
Oleuropein and its hydrolysate from extra virgin olive oil inhibit breast cancer cells proliferation interfering with the PI3K-AKT signal pathway Open
Naturally existing polyphenols in virgin olive oil possess significative biological activities and are potential nutraceutical therapeutic for breast cancer. In the present study, we investigated the anti-breast cancer activity of oleurope…
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Table of Contents Open
View article: Study on Potato Bud Cultivation Techniques in a Greenhouse in Spring
Study on Potato Bud Cultivation Techniques in a Greenhouse in Spring Open
The species degeneration caused by traditional potato cultivation methods is becoming increasingly evident, and it is particularly important to study new potato cultivation methods. Sprout planting technology has the advantages of large re…
View article: An innovative multi-modal retinal imaging system for in vivo retinal detection in small animals
An innovative multi-modal retinal imaging system for in vivo retinal detection in small animals Open
This paper presents an innovative retinal imaging system tailored for in vivo fundus detection in small animals. This system integrates Scanning Laser Ophthalmoscopy (SLO) and optical Coherence Tomography (OCT) techniques, enabling the sim…
View article: Optimization of Alkaline Hydrogen Peroxide Pretreatment and Enzymatic Hydrolysis of Wheat Straw for Enhancing Sugar Yields
Optimization of Alkaline Hydrogen Peroxide Pretreatment and Enzymatic Hydrolysis of Wheat Straw for Enhancing Sugar Yields Open
Optimization of alkaline hydrogen peroxide (AHP) pretreatment and enzymatic hydrolysis of wheat straw (WS) was carried out to enhance fermentable sugar yields with the use of glucose and xylose yields from the pretreated WS as responses. I…