Ye Zeng
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Author Swipe
View article: Unusual neutrophilic morphology in influenza-A-induced septic shock: Blue-green inclusions and phagocytosis of autologous cells in a toddler
Unusual neutrophilic morphology in influenza-A-induced septic shock: Blue-green inclusions and phagocytosis of autologous cells in a toddler Open
Influenza A virus is a major cause of seasonal respiratory illness, typically self-limiting in children. However, in rare instances, it can lead to fulminant systemic complications such as acute necrotizing encephalopathy (ANE), sepsis-ind…
View article: Advances in Mitochondrial Dysfunction and Its Role in Cardiovascular Diseases
Advances in Mitochondrial Dysfunction and Its Role in Cardiovascular Diseases Open
Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality worldwide and is attributed to complex pathophysiological mechanisms that surpass the traditional risk factors. Emerging evidence indicates that mitochondri…
View article: Analysis of the integration of medical and nursing care and its association with depression and anxiety among medical staff in the Jinhua area
Analysis of the integration of medical and nursing care and its association with depression and anxiety among medical staff in the Jinhua area Open
Objective To evaluate the relationship between implementation of the medical–nursing care integration model and the psychological health (depression and anxiety) of medical staff in the Jinhua area. Methods A total of 1,022 elderly patient…
View article: Frontal cortical gyrification mediates the association between hippocampal subfield microstructure and cognitive function in Parkinson's disease: A NODDI study highlighting olfactory dysfunction
Frontal cortical gyrification mediates the association between hippocampal subfield microstructure and cognitive function in Parkinson's disease: A NODDI study highlighting olfactory dysfunction Open
View article: Role of S1PR1 in VEGF-exosomes mediated resistance of hepatocellular carcinoma to anti-angiogenesis therapy
Role of S1PR1 in VEGF-exosomes mediated resistance of hepatocellular carcinoma to anti-angiogenesis therapy Open
View article: The ACSS2-PPARD-BCAT1 axis synchronously regulates branched-chain amino acid metabolism and development in pancreatic cancer
The ACSS2-PPARD-BCAT1 axis synchronously regulates branched-chain amino acid metabolism and development in pancreatic cancer Open
The characteristics of the tumor microenvironment (TME) of pancreatic cancer include an abundant stroma, hypoxia, insufficient blood supply and high degree of immunosuppression. Therefore, overcoming the TME conditions to reach a hypermeta…
View article: [Neuroprotective Effects of Anisodine Hydromide in a Rat Model of Vascular Dementia and the Antioxidative Stress Mechanisms Involved].
[Neuroprotective Effects of Anisodine Hydromide in a Rat Model of Vascular Dementia and the Antioxidative Stress Mechanisms Involved]. Open
AH modulates SOD and MDA levels and reduces oxidative stress injury, thereby improving neurological function and limb coordination and showing potential therapeutic effects in VD. The neuroprotective effects of AH may be related to its ant…
View article: Subcellular Organelles and Cellular Molecules: Localization, Detection, Prediction, and Diseases
Subcellular Organelles and Cellular Molecules: Localization, Detection, Prediction, and Diseases Open
View article: <italic>NCOA6</italic> knockdown enhances RSL3-induced ferroptosis in pancreatic cancer cells and increases the sensitivity to gemcitabine
<italic>NCOA6</italic> knockdown enhances RSL3-induced ferroptosis in pancreatic cancer cells and increases the sensitivity to gemcitabine Open
Ferroptosis is a type of programmed death characterized by iron-dependent lipid peroxidation, and targeting ferroptosis has been shown to efficiently kill highly aggressive cancer cells. Previously, we confirmed that nuclear receptors regu…
View article: Stacked Human Arterial Endothelial Cells Generate Atherosclerotic Fatty Streaks and Release Proinflammatory Cytokines
Stacked Human Arterial Endothelial Cells Generate Atherosclerotic Fatty Streaks and Release Proinflammatory Cytokines Open
Fatty streaks are the first sign of atherosclerosis. They consist of lipid-containing foam cells, which were believed to be derived from the monocytes in the blood through the leaky endothelium, and from the vascular smooth muscle cells mi…
View article: Single-cell sequencing reveals the heterogeneity of pancreatic neuroendocrine tumors under genomic instability and histological grading
Single-cell sequencing reveals the heterogeneity of pancreatic neuroendocrine tumors under genomic instability and histological grading Open
View article: Editorial: Glycocalyx in physiology and vascular related diseases–volume II
Editorial: Glycocalyx in physiology and vascular related diseases–volume II Open
Citation: Zeng Y and Fu BM (2024) Editorial: Glycocalyx in physiology and vascular related diseases–volume II. Front. Cell Dev. Biol. 12:1471251. doi: 10.3389/fcell.2024.1471251
View article: Syndecan-1 as a predictor of vulnerable atherosclerotic plaques
Syndecan-1 as a predictor of vulnerable atherosclerotic plaques Open
Aims Cardiovascular disease remains a major global health concern, with atherosclerosis (AS) being a significant contributor. Vulnerable plaques play a critical role in acute cardiovascular events. Syndecan-1 (SDC-1), a vital membrane prot…
View article: Investigating the Distribution and Antibiotic Resistance of Bacterial Pathogens in Clinical Specimens from a Chinese Maternal and Child Hospital: The Role of Environmental Factors
Investigating the Distribution and Antibiotic Resistance of Bacterial Pathogens in Clinical Specimens from a Chinese Maternal and Child Hospital: The Role of Environmental Factors Open
This study provides valuable insights into the distribution and antibiotic resistance patterns of bacterial pathogens in maternal and child healthcare facilities in Wuhan, China. Environmental factors significantly influence the epidemiolo…
View article: Harnessing Mitochondrial Stress for Health and Disease: Opportunities and Challenges
Harnessing Mitochondrial Stress for Health and Disease: Opportunities and Challenges Open
Mitochondria, essential organelles orchestrating cellular metabolism, have emerged as central players in various disease pathologies. Recent research has shed light on mitohormesis, a concept proposing an adaptive response of mitochondria …
View article: Spatial confinement modulates endothelial cell behavior and traction force in 3D hydrogel microgrooves
Spatial confinement modulates endothelial cell behavior and traction force in 3D hydrogel microgrooves Open
View article: Cancer immunometabolism: advent, challenges, and perspective
Cancer immunometabolism: advent, challenges, and perspective Open
View article: [Spatial Constraints of Rectangular Hydrogel Microgrooves Regulate the Morphology and Arrangement of Human Umbilical Vein Endothelial Cells].
[Spatial Constraints of Rectangular Hydrogel Microgrooves Regulate the Morphology and Arrangement of Human Umbilical Vein Endothelial Cells]. Open
Hydrogel microgrooves can regulate the morphology and orientation of HUVECs and mimic to a certain extent the in vivo microenvironment of vascular endothelial cells, providing an experimental model that bears better resemblance to h…
View article: Advances in micropillar arrays in cellular biomechanics detection and tissue engineering
Advances in micropillar arrays in cellular biomechanics detection and tissue engineering Open
View article: Advances in Regulating Cellular Behavior UsingMicropatterns
Advances in Regulating Cellular Behavior UsingMicropatterns Open
Micropatterns, characterized as distinct physical microstructures or chemical adhesion matrices on substance surfaces, have emerged as a powerful tool for manipulating cellular activity. By creating specific extracellular matrix microenvir…
View article: Epidemiological and clinical profile of pediatric hepatitis B virus infections in Wuhan: a retrospective cohort study
Epidemiological and clinical profile of pediatric hepatitis B virus infections in Wuhan: a retrospective cohort study Open
View article: Targeting FoxO1 in traditional Chinese medicine for the treatment of diabetes
Targeting FoxO1 in traditional Chinese medicine for the treatment of diabetes Open
Traditional Chinese medicine (TCM) encompasses treatment strategies for diabetes, which is referred to as "Consumptive Thirsty" syndrome. Recently, there has been discovery regarding the mapping between TCM and signaling molecules, which h…
View article: Modulation of muscarinic receptors by anisodine hydrobromide in cerebral ischemia
Modulation of muscarinic receptors by anisodine hydrobromide in cerebral ischemia Open
Ischemic cerebrovascular diseases pose significant challenges due to their high mortality, disability rates, and recurrence risk, imposing substantial societal and healthcare burdens. Current treatment modalities, including medication and …
View article: Micropillars in Biomechanics: Role in Guiding Mesenchymal Stem Cells Differentiation and Bone Regeneration
Micropillars in Biomechanics: Role in Guiding Mesenchymal Stem Cells Differentiation and Bone Regeneration Open
Efficient bone repair relies on biomaterials that exhibit superior biocompatibility and enhanced osteogenic capabilities. In recent, micropatterning technology has emerged as a robust strategy for directing stem cell differentiation, offer…
View article: Micro-circulating hyperdynamic blood flow as a key pathogenic factor in early sepsis
Micro-circulating hyperdynamic blood flow as a key pathogenic factor in early sepsis Open
Objective: The pathogenesis of sepsis is still unknown. Sepsis 3.0 points out that "how to define sepsis and septic shock itself is still a challenge". This study confirmed the inevitability and universality of Hyperdynamic microcirculatio…
View article: Association between Meteorological Factors and Pediatric Urinary Tract Infections in central China: a 6-years retrospective cohort of 2441 children with UTIs
Association between Meteorological Factors and Pediatric Urinary Tract Infections in central China: a 6-years retrospective cohort of 2441 children with UTIs Open
Backgrounds: To investigate the association between meteorological factors and common uropathogens in children with urinary tract infections (UTIs) and assesses the potential influence of weather conditions on pediatric UTIs. Methods: 2411…
View article: Recent research hotspots in sequencing and the pancreatic neuroendocrine tumor microenvironment
Recent research hotspots in sequencing and the pancreatic neuroendocrine tumor microenvironment Open
Multiple endocrine neoplasia 1 (MEN1) syndrome, a disease arising from a genetic predisposition to tumor development caused by MEN1 loss-of-function mutations, is characterized by the combined occurrence of neuroendocrine tumors in multipl…
View article: [Research progress on vascularization of organoids].
[Research progress on vascularization of organoids]. Open
Organoids are three-dimensional structures formed by self-organizing growth of cells in vitro, which own many structures and functions similar with those of corresponding in vivo organs. Although the organoid culture technolo…
View article: Improvement of hemodynamics in mesenteric microcirculation in septic shock rats by anisodamine and anisodine
Improvement of hemodynamics in mesenteric microcirculation in septic shock rats by anisodamine and anisodine Open
View article: Tumour associated endothelial cells: origin, characteristics and role in metastasis and anti-angiogenic resistance
Tumour associated endothelial cells: origin, characteristics and role in metastasis and anti-angiogenic resistance Open
Tumour progression and metastasis remain the leading causes of cancer-related death worldwide. Tumour angiogenesis is essential for tumour progression. The vasculature surrounding tumours is not only a transport channel for nutrients, oxyg…