Zengli Yu
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View article: Biomonitoring of toxic metals and associated risk factors in a high vulnerable population in Gilgit-Baltistan, Pakistan
Biomonitoring of toxic metals and associated risk factors in a high vulnerable population in Gilgit-Baltistan, Pakistan Open
View article: ElasWave: An Elastic-Native System for Scalable Hybrid-Parallel Training
ElasWave: An Elastic-Native System for Scalable Hybrid-Parallel Training Open
Large-scale LLM pretraining now runs across $10^5$--$10^6$ accelerators, making failures routine and elasticity mandatory. We posit that an elastic-native training system must jointly deliver (i) parameter consistency, (ii) low mean time t…
View article: EAT-Lancet diet and risk of metabolic dysfunction-associated steatotic liver disease and other liver chronic diseases: a large prospective cohort study in the UK Biobank
EAT-Lancet diet and risk of metabolic dysfunction-associated steatotic liver disease and other liver chronic diseases: a large prospective cohort study in the UK Biobank Open
Background and aim As a newly recommended healthy dietary blueprint, the EAT-Lancet diet emphasizes both environmental sustainability and human health. However, its impact on chronic liver diseases remains unclear. This study examined the …
View article: The mediating mechanism of Oct4 in the process of cleft palate induced by 2, 3, 7, 8-tetrachlorodibenz-p-dioxin (TCDD) and all-trans retinoic acid
The mediating mechanism of Oct4 in the process of cleft palate induced by 2, 3, 7, 8-tetrachlorodibenz-p-dioxin (TCDD) and all-trans retinoic acid Open
2, 3, 7, 8-tetrachlorodiphenyl-p-dioxin (TCDD) and all-trans retinoic acid (atRA) have been shown to be inducers of cleft palate (CP). Relevant studies have shown that Oct transcription factor 4 (Oct4) can regulate the expression of the ar…
View article: Evaluating the Carcinogenic and Non-Carcinogenic Health Risks of Heavy Metals Contamination in Drinking Water, Vegetables, and Soil from Gilgit-Baltistan, Pakistan
Evaluating the Carcinogenic and Non-Carcinogenic Health Risks of Heavy Metals Contamination in Drinking Water, Vegetables, and Soil from Gilgit-Baltistan, Pakistan Open
Environmental pollutants significantly impact health and quality of life. High levels of harmful metals in drinking water, vegetables, and soil can accumulate in the body, leading to serious health issues. In Gilgit-Baltistan, Pakistan, th…
View article: Human health risks assessment of toxic metals via water, food, and soil: A case study of Northern areas (Ghizer and Gilgit) of Pakistan
Human health risks assessment of toxic metals via water, food, and soil: A case study of Northern areas (Ghizer and Gilgit) of Pakistan Open
Health concerns have arisen worldwide as a result of contaminated food and water. This study was aimed to determine the levels of selected heavy metals i.e. cadmium (Cd), chromium (Cr), copper (Cu) manganese (Mn), and nickel (Ni) in variou…
View article: Table S1 from The role of protein arginine methyltransferases in pathogenesis and treatment of digestive system carcinoma
Table S1 from The role of protein arginine methyltransferases in pathogenesis and treatment of digestive system carcinoma Open
Table S1 shows the application of PRMT inhibitors in gastrointestinal tumors.
View article: Table S1 from The role of protein arginine methyltransferases in pathogenesis and treatment of digestive system carcinoma
Table S1 from The role of protein arginine methyltransferases in pathogenesis and treatment of digestive system carcinoma Open
Table S1 shows the application of PRMT inhibitors in gastrointestinal tumors.
View article: Data from The role of protein arginine methyltransferases in pathogenesis and treatment of digestive system carcinoma
Data from The role of protein arginine methyltransferases in pathogenesis and treatment of digestive system carcinoma Open
Post-translational modification of proteins increases their diversity and maintains the stability of the intracellular environment. Protein arginine methyltransferases (PRMTs) are an important family of epigenetic modification enzymes, whi…
View article: Correction to: Dynamic changes in ambient PM2.5 and body mass index among old adults: a nationwide cohort study
Correction to: Dynamic changes in ambient PM2.5 and body mass index among old adults: a nationwide cohort study Open
View article: Recognition and detection technology for microplastic, its source and health effects
Recognition and detection technology for microplastic, its source and health effects Open
Microplastic (MP) is ubiquitous in the environment which appeared as an immense intimidation to human and animal health. The plastic fragments significantly polluted the ocean, fresh water, food chain, and other food items. Inadequate main…
View article: The Brain Structure, Biological Pathways, and Genetic Mechanisms Underlying the Relationship between Accelerated Biological Aging and Dementia
The Brain Structure, Biological Pathways, and Genetic Mechanisms Underlying the Relationship between Accelerated Biological Aging and Dementia Open
View article: Cadmium-induced reproductive toxicity combined with a correlation to the oogenesis process and competing endogenous RNA networks based on a Caenorhabditis elegans model
Cadmium-induced reproductive toxicity combined with a correlation to the oogenesis process and competing endogenous RNA networks based on a Caenorhabditis elegans model Open
Accumulation of the heavy metal Cadmium (Cd) in the ovaries and placenta can affect the structure and function of these organs and induce female reproductive toxicity. This toxicity may be due to Cd's similarity to estrogen and its ability…
View article: Association of greenspace with hypertension in adult: a systematic review and meta-analysis of epidemiological studies
Association of greenspace with hypertension in adult: a systematic review and meta-analysis of epidemiological studies Open
Several studies have investigated the relationship of greenspace with blood pressure (BP) and hypertension, but the results were inconsistent. We aimed to assess the relationship of greenspace with BP/hypertension. We searched PubMed, Emba…
View article: Ambient particulate matter, maternal thyroid function, and birth weight: A mediation analysis
Ambient particulate matter, maternal thyroid function, and birth weight: A mediation analysis Open
Maternal PM exposure may induce a reduction in newborn BW by affecting the maternal TH concentrations.
View article: Data from The Role of Protein Arginine Methyltransferases in Pathogenesis and Treatment of Digestive System Carcinoma
Data from The Role of Protein Arginine Methyltransferases in Pathogenesis and Treatment of Digestive System Carcinoma Open
Posttranslational modification of proteins increases their diversity and maintains the stability of the intracellular environment. Protein arginine methyltransferases (PRMT) are an important family of epigenetic modification enzymes, which…
View article: Table S1 from The Role of Protein Arginine Methyltransferases in Pathogenesis and Treatment of Digestive System Carcinoma
Table S1 from The Role of Protein Arginine Methyltransferases in Pathogenesis and Treatment of Digestive System Carcinoma Open
Table S1 shows the application of PRMT inhibitors in gastrointestinal tumors.
View article: Table S1 from The Role of Protein Arginine Methyltransferases in Pathogenesis and Treatment of Digestive System Carcinoma
Table S1 from The Role of Protein Arginine Methyltransferases in Pathogenesis and Treatment of Digestive System Carcinoma Open
Table S1 shows the application of PRMT inhibitors in gastrointestinal tumors.
View article: Data from The Role of Protein Arginine Methyltransferases in Pathogenesis and Treatment of Digestive System Carcinoma
Data from The Role of Protein Arginine Methyltransferases in Pathogenesis and Treatment of Digestive System Carcinoma Open
Posttranslational modification of proteins increases their diversity and maintains the stability of the intracellular environment. Protein arginine methyltransferases (PRMT) are an important family of epigenetic modification enzymes, which…
View article: Spatiotemporal Trends of Stroke Burden Attributable to Ambient PM <sub>2.5</sub> in 204 Countries and Territories, 1990–2019
Spatiotemporal Trends of Stroke Burden Attributable to Ambient PM <sub>2.5</sub> in 204 Countries and Territories, 1990–2019 Open
The global burden of stroke attributable to ambient PM2.5 showed an increasing trend over the past 30 years, especially in male patients, low-income countries, and for ICH. Continued efforts on reducing the level of ambient PM
View article: Atopic dermatitis and chronic kidney disease: a bidirectional Mendelian randomization study
Atopic dermatitis and chronic kidney disease: a bidirectional Mendelian randomization study Open
Background A bidirectional association between atopic dermatitis and chronic kidney disease (CKD) has been revealed in observational studies, whereas the causality of this association was unclear. We conducted a Mendelian randomization stu…
View article: Sex Specificity in the Mixed Effects of Blood Heavy Metals and Cognitive Function on Elderly: Evidence from NHANES
Sex Specificity in the Mixed Effects of Blood Heavy Metals and Cognitive Function on Elderly: Evidence from NHANES Open
The way that males and females react to environmental exposures and negative impacts on their neurological systems is often different. Although previous research has examined the cognitively impairing effects of solitary metal exposures, t…
View article: The association between retinol-binding protein 4 and risk of type 2 diabetes: A systematic review and meta-analysis
The association between retinol-binding protein 4 and risk of type 2 diabetes: A systematic review and meta-analysis Open
Retinol-binding protein 4 (RBP4) was controversially associated with type 2 diabetes mellitus (T2DM). This meta-analysis aimed at evaluating the association between RBP4 level and T2DM risk. MEDLINE and EMBASE were searched to identify rel…
View article: Association between diverticular disease and colorectal cancer: a bidirectional mendelian randomization study
Association between diverticular disease and colorectal cancer: a bidirectional mendelian randomization study Open
Background: Diverticular disease has been inconsistently associated with colorectal cancer risk. We conducted a bidirectional Mendelian randomization study to assess this association. Methods: Forty-three and seventy single-nucleotide poly…
View article: Naringin Alleviates Glucose-Induced Aging by Reducing Fat Accumulation and Promoting Autophagy in Caenorhabditis elegans
Naringin Alleviates Glucose-Induced Aging by Reducing Fat Accumulation and Promoting Autophagy in Caenorhabditis elegans Open
Naringin (Nar) is a dihydroflavonoid compound, widely found in citrus fruit and used in Chinese herbal medicine. As a phytochemical, it acts as a dietary supplement that can delay aging and prevent aging-related disease, such as obesity an…
View article: Microbiota from Exercise Mice Counteracts High-Fat High-Cholesterol Diet-Induced Cognitive Impairment in C57BL/6 Mice
Microbiota from Exercise Mice Counteracts High-Fat High-Cholesterol Diet-Induced Cognitive Impairment in C57BL/6 Mice Open
Gut microbes may be the critical mediators for the cognitive enhancing effects of exercise. Via fecal microbiota transplantation (FMT), this study is aimed at determining the mechanism of how voluntary exercise improved learning and memory…
View article: Interaction effects of night-time temperature and PM2.5 on preterm birth in Huai River Basin, China
Interaction effects of night-time temperature and PM2.5 on preterm birth in Huai River Basin, China Open
Nocturnal temperature is observed increasing with global warming. However, evidence on night-time non-optimal temperature on the risk of preterm birth (PTB) is limited, and the potential interactions with air pollution on PTB has not been …
View article: Transition from Solid to Clean Fuels Benefits Sleep: A Nationwide Population-Based Longitudinal Study in China
Transition from Solid to Clean Fuels Benefits Sleep: A Nationwide Population-Based Longitudinal Study in China Open
View article: Green space, air pollution and gestational diabetes mellitus: A retrospective cohort study in central China
Green space, air pollution and gestational diabetes mellitus: A retrospective cohort study in central China Open
Emerging evidence suggests residential surrounding green space is beneficial for human health. The association between green space and GDM showed inconsistent results, and potential effect modification of green space with air pollution is …
View article: Effects of folic acid on oxidative damage of kidney in lead-exposed rats
Effects of folic acid on oxidative damage of kidney in lead-exposed rats Open
Introduction Lead (Pb) has many applications in daily life, but in recent years, various problems caused by lead exposure have aroused people’s concern. Folic acid is widely found in fruits and has received more attention for its antioxida…