Zeqian Yu
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View article: MMA-induced LOXL2+ PSCs promote linear ECM alignment in the aging pancreas leading to pancreatic cancer progression
MMA-induced LOXL2+ PSCs promote linear ECM alignment in the aging pancreas leading to pancreatic cancer progression Open
View article: Different impact of anastomotic leak on long-term recurrence after surgery for rectal vs colonic cancer A systemic review and meta-analysis
Different impact of anastomotic leak on long-term recurrence after surgery for rectal vs colonic cancer A systemic review and meta-analysis Open
Background Long-term recurrence after resection for colorectal cancer (CRC) might be influenced by anastomotic leak (AL). Recent studies investigating this topic have reported discrepant findings. Materials: Studies investigating the impac…
View article: Development of a PPP1R14B-associated immune prognostic model for hepatocellular carcinoma
Development of a PPP1R14B-associated immune prognostic model for hepatocellular carcinoma Open
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide. Immunotherapy has been widely reported to have sustained and strong antitumor effects in a variety of tumors with active immune microenvironments…
View article: <scp>LncRNA HClnc1</scp> facilitates hepatocellular carcinoma progression by regulating <scp>PKM2</scp> signaling and indicates poor survival outcome after hepatectomy
<span>LncRNA HClnc1</span> facilitates hepatocellular carcinoma progression by regulating <span>PKM2</span> signaling and indicates poor survival outcome after hepatectomy Open
Aim Long noncoding RNAs (lncRNAs) are key mediators with a wide range of pathophysiological functions, but their role in human hepatocellular carcinoma (HCC) is still unclear. Methods An unbiased microarray study evaluated a novel lncRNA, …
View article: mTORC2 promotes pancreatic cancer progression and parp inhibitor resistance
mTORC2 promotes pancreatic cancer progression and parp inhibitor resistance Open
Pancreatic cancer is one of the most aggressive cancers with a median survival time of less than 5 months, and conventional chemotherapeutics are the main treatment strategy. Poly(ADP-ribose) polymerase (PARP) inhibitors have been recently…
View article: MicroRNA-140-5p Suppresses The PD-L1 Level In Exosomes Derived From Hepatocellular Carcinoma Cells, Thereby Attenuating The Chemoresistance, Autophagy And Stemness Induced By Sorafenib In Hepatocellular Carcinoma
MicroRNA-140-5p Suppresses The PD-L1 Level In Exosomes Derived From Hepatocellular Carcinoma Cells, Thereby Attenuating The Chemoresistance, Autophagy And Stemness Induced By Sorafenib In Hepatocellular Carcinoma Open
Background: Sorafenib (SO), inhibitor of receptor tyrosine kinase, possesses anti-tumor ability in hepatocellular carcinoma (HCC) by anti-angiogenic effects. However, patients with advanced HCC are resistant to SO. Dysregulated micro-RNA (…
View article: Corrigendum to “Effects of Arsenic Trioxide-Loaded PLGA Nanoparticles on Proliferation and Migration of Human Vascular Smooth Muscle Cells”
Corrigendum to “Effects of Arsenic Trioxide-Loaded PLGA Nanoparticles on Proliferation and Migration of Human Vascular Smooth Muscle Cells” Open
View article: Allicin depresses biological activities of pancreatic cancer cells by regulating miRNA-339-5p/ZNF-689 axis
Allicin depresses biological activities of pancreatic cancer cells by regulating miRNA-339-5p/ZNF-689 axis Open
Introduction The aim of this study was to discuss Allicin’s anti-tumor effects and relative in pancreatic cancer cell via vitro and vivo study. Material and methods Using PANC-1 and Hs766T cell as research cell lines in our study. The PANC…
View article: Effects of Arsenic Trioxide-Loaded PLGA Nanoparticles on Proliferation and Migration of Human Vascular Smooth Muscle Cells
Effects of Arsenic Trioxide-Loaded PLGA Nanoparticles on Proliferation and Migration of Human Vascular Smooth Muscle Cells Open
Backgroud. To evaluate improvement of arsenic trioxide-loaded PLGA nanoparticles (As2O3-PLGA-NPs) to Human Vascular Smooth Muscle Cells (HUVSMCs) in vitro. Methods. As2O3-PLGA-NPs were synthesized and characterized by transmission electron…
View article: Role of long intergenic non-protein coding RNA 00152 in pancreatic cancer glycolysis <i>via</i> the manipulation of the microRNA-185-5p/Krüppel-like factor 7 axis
Role of long intergenic non-protein coding RNA 00152 in pancreatic cancer glycolysis <i>via</i> the manipulation of the microRNA-185-5p/Krüppel-like factor 7 axis Open
The current study set out to investigate the role of long intergenic non-protein coding RNA (LINC) 00152 in pancreatic cancer (PC) cell glycolysis with the microRNA (miR)-185-5p/Krüppel-like factor 7 (KLF7) axis. Firstly, PC tissues and ce…
View article: miRNA-339-5p Plays an Important Role in Invasion and Migration of Pancreatic Cancer Cells
miRNA-339-5p Plays an Important Role in Invasion and Migration of Pancreatic Cancer Cells Open
BACKGROUND This study aimed to investigate the role of miRNA-339-5p in pancreatic cancer cell invasion and migration. MATERIAL AND METHODS The differences between exosomal miRNAs of PANC02 and PANC02-H7 were studied by microarray analysis.…
View article: Conditional survival in patients with spontaneous tumor rupture of hepatocellular carcinoma after partial hepatectomy: a propensity score matching analysis
Conditional survival in patients with spontaneous tumor rupture of hepatocellular carcinoma after partial hepatectomy: a propensity score matching analysis Open
View article: Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation
Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation Open
Exosomes play important roles in cell-cell communication, and are likely mediators of the metastatic cascade in cancer. This study examined the role of exosomes in pancreatic cancer cell adhesion, migration, and invasion. We isolated and p…
View article: Diabetes mellitus stimulates pancreatic cancer growth and epithelial-mesenchymal transition-mediated metastasis via a p38 MAPK pathway
Diabetes mellitus stimulates pancreatic cancer growth and epithelial-mesenchymal transition-mediated metastasis via a p38 MAPK pathway Open
Diabetes mellitus (DM) and its accompanying chronic inflammation promote tumor progression. p38 mitogen-activated protein kinase (MAPK) is an essential kinase for inflammation. The effects of p38 MAPK on epithelial-mesenchymal transition (…