Zhidao Xia
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View article: The Formation Factors and Influences of Separation Anxiety Among Students in the Secondary Education Stage
The Formation Factors and Influences of Separation Anxiety Among Students in the Secondary Education Stage Open
The separation anxiety of students in secondary education has been widely studied, but the current research focuses on medical mitigation methods, and there are still deficiencies in the exploration of the group-specific intervention and t…
View article: Enhanced Osteogenesis by Combining Exogenous BMPs with Hydroxyapatite/Aragonite Bone Grafts: In Vitro and In Vivo Studies
Enhanced Osteogenesis by Combining Exogenous BMPs with Hydroxyapatite/Aragonite Bone Grafts: In Vitro and In Vivo Studies Open
Synthetic biomaterials are widely used as bone graft substitutes, but their osteogenic capacity is limited as they lack osteogenic growth factors. This study aimed to enhance the osteogenesis of a novel hydroxyapatite/aragonite (HAA) bioma…
View article: Bone marrow microenvironment and organ chips: Advances in tumor dormancy research
Bone marrow microenvironment and organ chips: Advances in tumor dormancy research Open
Bone metastasis presents a major challenge in oncology, often involving prolonged tumor dormancy within the complex bone marrow microenvironment (BMME). This dormancy, characterized by halted proliferation but sustained viability, poses ri…
View article: Organoid‐tissue extracellular vesicles
Organoid‐tissue extracellular vesicles Open
Extracellular vesicles (EVs) are lipid bilayer structures secreted by cells that act as intercellular messengers. Tissue‐derived EVs (TEVs), harvested from the tissue interstitium, directly reflect the actual physiological or pathological …
View article: Prussian blue nanohybrid hydrogel combined with specific far-infrared based on graphene devices for promoting diabetic wound healing
Prussian blue nanohybrid hydrogel combined with specific far-infrared based on graphene devices for promoting diabetic wound healing Open
Diabetic wounds are difficult to treat in nature due to their distinct pathophysiological characteristics, such as inflammation and/or oxidative stress, which offers an opportunity to employ nanozymes. However, nanozymes may cause safety c…
View article: Genetic analyses identify circulating genes related to brain structures associated with Parkinson’s disease
Genetic analyses identify circulating genes related to brain structures associated with Parkinson’s disease Open
View article: Viewpoint: Artificial intelligence or cosmogenic intelligence?
Viewpoint: Artificial intelligence or cosmogenic intelligence? Open
View article: Cosmogenic intelligence: The silent power.
Cosmogenic intelligence: The silent power. Open
View article: Doe-1: Closed-Loop Autonomous Driving with Large World Model
Doe-1: Closed-Loop Autonomous Driving with Large World Model Open
End-to-end autonomous driving has received increasing attention due to its potential to learn from large amounts of data. However, most existing methods are still open-loop and suffer from weak scalability, lack of high-order interactions,…
View article: Standardization and consensus in the development and application of bone organoids
Standardization and consensus in the development and application of bone organoids Open
Organoids, self-organized structures derived from stem cells cultured in a specific three-dimensional (3D) in vitro microenvironment, have emerged as innovative platforms that closely mimic in vivo cellular behavior, tissue a…
View article: Rapid assessment of the osteogenic capacity of hydroxyapatite/aragonite using a murine tibial periosteal ossification model
Rapid assessment of the osteogenic capacity of hydroxyapatite/aragonite using a murine tibial periosteal ossification model Open
View article: Runx2 controls the osteogenic fate of growth plate chondrocytes
Runx2 controls the osteogenic fate of growth plate chondrocytes Open
View article: POLE2 promotes osteosarcoma progression by enhancing the stability of CD44
POLE2 promotes osteosarcoma progression by enhancing the stability of CD44 Open
View article: Knee osteoarthritis pendulum therapy: In vivo evaluation and a randomised, single-blind feasibility clinical trial
Knee osteoarthritis pendulum therapy: In vivo evaluation and a randomised, single-blind feasibility clinical trial Open
The research aimed to investigate the effect of an ancient leg-swinging exercise on knee osteoarthritis. A minipig animal model was used to establish the potential mechanism underlying the exercise of knee osteoarthritis pendulum therapy, …
View article: Organoids: the future of disease modelling and therapeutics.
Organoids: the future of disease modelling and therapeutics. Open
View article: Membrane-coated nanoparticles as a biomimetic targeted delivery system for tumour therapy.
Membrane-coated nanoparticles as a biomimetic targeted delivery system for tumour therapy. Open
Drug therapy towards tumours often causes adverse effects because of their non-specific nature. Membrane-coated technology and membrane-coated nanoparticles provide an advanced and promising platform of targeted and safe delivery. By camou…
View article: Skeletal organoids.
Skeletal organoids. Open
The skeletal system, composed of bones, muscles, joints, ligaments, and tendons, serves as the foundation for maintaining human posture, mobility, and overall biomechanical functionality. However, with ageing, chronic overuse, and acute in…
View article: Artificial intelligence-enabled studies on organoid and organoid extracellular vesicles.
Artificial intelligence-enabled studies on organoid and organoid extracellular vesicles. Open
View article: Generation artificial intelligence (GenAI) and <i>Biomaterials Translational</i>: steering innovation without misdirection.
Generation artificial intelligence (GenAI) and <i>Biomaterials Translational</i>: steering innovation without misdirection. Open
View article: Microneedle-Assisted Transfersomes as a Transdermal Delivery System for Aspirin
Microneedle-Assisted Transfersomes as a Transdermal Delivery System for Aspirin Open
Transdermal drug delivery systems offer several advantages over conventional oral or hypodermic administration due to the avoidance of first-pass drug metabolism and gastrointestinal degradation as well as patients’ convenience due to a mi…
View article: Dbh+ catecholaminergic cardiomyocytes contribute to the structure and function of the cardiac conduction system in murine heart
Dbh+ catecholaminergic cardiomyocytes contribute to the structure and function of the cardiac conduction system in murine heart Open
View article: A pilot, feasibility randomised, controlled trial comparing walking exercise against pendulum leg swinging exercise in adults with osteoarthritis of the knee. (Preprint)
A pilot, feasibility randomised, controlled trial comparing walking exercise against pendulum leg swinging exercise in adults with osteoarthritis of the knee. (Preprint) Open
BACKGROUND In China, swinging the leg backwards and forwards is a commonly used therapy for people with osteoarthritis of the knee. One rationale is that movement without weightbearing may reduce pain of the knee by strengthening the musc…
View article: Editorial: Diagnosis and treatment of bone metastases
Editorial: Diagnosis and treatment of bone metastases Open
EDITORIAL article Front. Oncol., 15 August 2023Sec. Surgical Oncology Volume 13 - 2023 | https://doi.org/10.3389/fonc.2023.1247231
View article: Efficient calculation of fluid-induced wall shear stress within tissue engineering scaffolds by an empirical model
Efficient calculation of fluid-induced wall shear stress within tissue engineering scaffolds by an empirical model Open
View article: Targeting of the Interleukin-13 Receptor (IL-13R)α2 Expressing Prostate Cancer by a Novel Hybrid Lytic Peptide
Targeting of the Interleukin-13 Receptor (IL-13R)α2 Expressing Prostate Cancer by a Novel Hybrid Lytic Peptide Open
The IL-13Rα2 cell surface receptor is highly expressed in tumours such as prostate cancer. In this report, we evaluated the hypothesis that prostate cancer cells with enhanced IL-13Rα2 expression are a suitable target for the hybrid lytic …
View article: The emergence of AI tools in scientific writing and research.
The emergence of AI tools in scientific writing and research. Open
View article: Combination of cobalt, chromium and titanium nanoparticles increases cytotoxicity in vitro and pro-inflammatory cytokines in vivo
Combination of cobalt, chromium and titanium nanoparticles increases cytotoxicity in vitro and pro-inflammatory cytokines in vivo Open
View article: Integrated transcriptome and lineage analyses reveal novel catecholaminergic cardiomyocytes contributing to the cardiac conduction system in murine heart
Integrated transcriptome and lineage analyses reveal novel catecholaminergic cardiomyocytes contributing to the cardiac conduction system in murine heart Open
Summary Cardiac conduction system (CCS) morphogenesis is essential for correct heart function yet is incompletely understood. Here we established the transcriptional landscape of cell types populating the developing heart by integrating si…
View article: Editorial: Tissue Stem Cells During Trauma: From Basic Biology to Translational Medicine
Editorial: Tissue Stem Cells During Trauma: From Basic Biology to Translational Medicine Open
EDITORIAL article Front. Cell Dev. Biol., 26 May 2022Sec. Stem Cell Research https://doi.org/10.3389/fcell.2022.914582
View article: A pilot, feasibility randomised, controlled trial comparing walking exercise against pendulum leg swinging exercise in adults with osteoarthritis of the knee.
A pilot, feasibility randomised, controlled trial comparing walking exercise against pendulum leg swinging exercise in adults with osteoarthritis of the knee. Open
Background. In China, swinging the leg backwards and forwards is a commonly used therapy for people with osteoarthritis of the knee. One rationale is that movement without weightbearing may increase the range of movement by allowing a grea…