Zhenqiang Xu
YOU?
Author Swipe
View article: Egg-laying ChickenGTEx resource deciphers context-specific regulatory effects on fertility traits
Egg-laying ChickenGTEx resource deciphers context-specific regulatory effects on fertility traits Open
View article: Case Report: A Chinese woman with primary Sjögren’s syndrome presented with simultaneous involvement of the cerebral and coronary arteries as initial symptoms
Case Report: A Chinese woman with primary Sjögren’s syndrome presented with simultaneous involvement of the cerebral and coronary arteries as initial symptoms Open
Introduction Primary Sjögren’s syndrome (pSS) is a heterogeneous autoimmune disorder that may be associated with systemic manifestations such as pulmonary or articular involvement.Compared to other autoimmune diseases, vascular injury and …
View article: A randomized, open-label, multi-center, active-controlled phase II study comparing abiraterone acetate tablets (II), an improved formulation, versus originator abiraterone acetate in patients with metastatic castration-resistant prostate cancer
A randomized, open-label, multi-center, active-controlled phase II study comparing abiraterone acetate tablets (II), an improved formulation, versus originator abiraterone acetate in patients with metastatic castration-resistant prostate cancer Open
ClinicalTrials.gov, NCT04862091.
View article: GCRP: Integrated Global Chicken Reference Panel from 11,951 Chicken Genomes
GCRP: Integrated Global Chicken Reference Panel from 11,951 Chicken Genomes Open
Chickens are a crucial source of protein for humans and a popular model animal for bird research. Despite the emergence of imputation as a reliable genotyping strategy for large populations, the lack of a high-quality chicken reference pan…
View article: Research on the Impact Path of New Quality Productivity on the High Quality Development of the Construction Industry
Research on the Impact Path of New Quality Productivity on the High Quality Development of the Construction Industry Open
As a pivotal pillar of the national economy, the construction industry plays a crucial role in promoting urbanization and providing employment opportunities in China's social development. The development of new productive forces has furthe…
View article: Knockdown of growth differentiation factor-15 restrains prostate cancer throughregulating MAPK/ERK signaling pathway
Knockdown of growth differentiation factor-15 restrains prostate cancer throughregulating MAPK/ERK signaling pathway Open
Prostate cancer, prevalent among males, is influenced by various molecular factors, including Growth Differentiation Factor 15 (GDF15). Despite its recognized role in multiple tumor types, GDF15's specific involvement in prostate cancer re…
View article: Weighted single-step GWAS identified candidate genes associated with carcass traits in a Chinese yellow-feathered chicken population
Weighted single-step GWAS identified candidate genes associated with carcass traits in a Chinese yellow-feathered chicken population Open
Carcass traits in broiler chickens are complex traits that are influenced by multiple genes. To gain deeper insights into the genetic mechanisms underlying carcass traits, here we conducted a weighted single-step genome-wide association st…
View article: Evaluation of the selection of key individuals for genotype imputation in Chinese yellow-feathered chicken
Evaluation of the selection of key individuals for genotype imputation in Chinese yellow-feathered chicken Open
Genotype imputation is a powerful technique employed by next-generation sequencing (NGS) and genotyping arrays, which can significantly enhance the cost-effectiveness and efficiency of genomic selection. The accuracy of imputation is large…
View article: Haplotype analysis of genomic prediction by incorporating genomic pathway information based on high-density SNP marker in Chinese yellow-feathered chicken
Haplotype analysis of genomic prediction by incorporating genomic pathway information based on high-density SNP marker in Chinese yellow-feathered chicken Open
Genomic selection using single nucleotide polymorphism (SNP) markers is now intensively investigated in breeding and has been widely utilized for genetic improvement. Currently, several studies have used haplotype (consisting of multiallel…
View article: Association of Serum Anion Gap and Risk of Long-term Mortality in Patients Following Coronary Artery Bypass Grafting: A Propensity Score Matching Study
Association of Serum Anion Gap and Risk of Long-term Mortality in Patients Following Coronary Artery Bypass Grafting: A Propensity Score Matching Study Open
Background: The present study aimed to explore the relationship between serum anion gap (AG) and long-term mortality in patients undergoing coronary artery bypass grafting (CABG). Methods: Clinical variables were extracted among patients u…
View article: Dysphagia Caused by the Unruptured Aneurysm in the Left Sinus of Valsalva
Dysphagia Caused by the Unruptured Aneurysm in the Left Sinus of Valsalva Open
View article: MicroRNA-4735-3p Facilitates Ferroptosis in Clear Cell Renal Cell Carcinoma by Targeting SLC40A1
MicroRNA-4735-3p Facilitates Ferroptosis in Clear Cell Renal Cell Carcinoma by Targeting SLC40A1 Open
Objective. Clear cell renal cell carcinoma (ccRCC) is the major histopathological subtype of renal cancer, and ferroptosis is implicated in the pathogenesis of ccRCC. The present study was aimed at investigating the role and underlying mec…
View article: Predictive Value of Blood Urea Nitrogen to Albumin Ratio in Long-Term Mortality in Intensive Care Unit Patients with Acute Myocardial Infarction: A Propensity Score Matching Analysis
Predictive Value of Blood Urea Nitrogen to Albumin Ratio in Long-Term Mortality in Intensive Care Unit Patients with Acute Myocardial Infarction: A Propensity Score Matching Analysis Open
Diming Zhao,1 Yilin Liu,2 Shanghao Chen,1 Zhenqiang Xu,3,4 Xiaomei Yang,5 Hechen Shen,1 Shijie Zhang,1 Yi Li,1 Haizhou Zhang,3,4 Chengwei Zou,3,4 Xiaochun Ma3,4 1Department of Cardiovascular Surgery, Shandong Provincial Hospital, Cheeloo C…
View article: Blood Urea Nitrogen-to-Albumin Ratio in Predicting Long-Term Mortality in Patients Following Coronary Artery Bypass Grafting: An Analysis of the MIMIC-III Database
Blood Urea Nitrogen-to-Albumin Ratio in Predicting Long-Term Mortality in Patients Following Coronary Artery Bypass Grafting: An Analysis of the MIMIC-III Database Open
Background This study examined the role of blood urea nitrogen-to-albumin ratio (BAR) in predicting long-term mortality in patients undergoing coronary artery bypass grafting (CABG). Methods In this retrospective cohort study, patients und…
View article: Integrative Bioinformatics Analysis Revealed Mitochondrial Defects Underlying Hypoplastic Left Heart Syndrome
Integrative Bioinformatics Analysis Revealed Mitochondrial Defects Underlying Hypoplastic Left Heart Syndrome Open
The present study applied the integrative bioinformatics analysis and revealed the mitochondrial-related key genes, regulatory pathways, TFs and miRNAs underlying the HF in HLHS, which improved the understanding of disease mechanisms and t…
View article: Genome‑wide association study and genomic prediction for growth traits in yellow-plumage chicken using genotyping-by-sequencing
Genome‑wide association study and genomic prediction for growth traits in yellow-plumage chicken using genotyping-by-sequencing Open
View article: Influence of Androgen Receptor Antagonist MDV3100 Therapy on Rats With Benign Prostatic Hyperplasia
Influence of Androgen Receptor Antagonist MDV3100 Therapy on Rats With Benign Prostatic Hyperplasia Open
Purpose: To probe the effect and mechanism of androgen receptor antagonist MDV3100 on benign prostatic hyperplasia (BPH) of ratsMethods: BPH rat model was induced by testosterone propionate. Then antagomir-miR-21-3p or agomir-miR-21-3p was…
View article: Coronary artery vasculitis in a patient of Behçet’s disease.
Coronary artery vasculitis in a patient of Behçet’s disease. Open
We report a case of coronary artery vasculitis in Behçet’s disease. The patient was treated with the off-pump coronary artery bypass grafting. This case shows the diagnostic value of coronary computed tomography angiography in coronary art…
View article: Additional file 2 of Genome‑wide association study and genomic prediction for growth traits in yellow-plumage chicken using genotyping-by-sequencing
Additional file 2 of Genome‑wide association study and genomic prediction for growth traits in yellow-plumage chicken using genotyping-by-sequencing Open
Additional file 2: Table S1. Information on the significant SNPs associated with 42 DW in the QTL region on chromosome 4. The data present the genomic location, effect, heritability, P value, and functional annotation of each GWAS signific…
View article: High salt-induced weakness of anti-oxidative function of natriuretic peptide receptor-C and podocyte damage in the kidneys of Dahl rats
High salt-induced weakness of anti-oxidative function of natriuretic peptide receptor-C and podocyte damage in the kidneys of Dahl rats Open
Background: Atrial natriuretic peptide (ANP) and its natriuretic peptide receptors A (NPR-A) and C (NPR-C) are involved in the regulation of physiological and pathophysiological process of blood pressure. The present study aimed to determi…
View article: Expression levels of paraoxonase-1 in aortic valve tissue are associated with the progression of calcific aortic valve stenosis
Expression levels of paraoxonase-1 in aortic valve tissue are associated with the progression of calcific aortic valve stenosis Open
We detected PON1 in the aortic valve for the first time, and our results suggest that the PON1 level in aortic valve tissue decreases with increasing severity of aortic valve stenosis.
View article: Predictive Roles of Neutrophil-to-Lymphocyte Ratio and C-Reactive Protein in Patients with Calcific Aortic Valve Disease
Predictive Roles of Neutrophil-to-Lymphocyte Ratio and C-Reactive Protein in Patients with Calcific Aortic Valve Disease Open
The neutrophil-to-lymphocyte ratio (NLR) and C-reactive protein (CRP) are emerging indirect blood markers to roughly reflect the inflammation level in our body while some pathological changes occurring in aortic valve tissue. Few recent st…
View article: The effects of hyperoxia liquid regulate cardiopulmonary bypass‑induced myocardial damage through the Nrf2‑ARE signaling pathway
The effects of hyperoxia liquid regulate cardiopulmonary bypass‑induced myocardial damage through the Nrf2‑ARE signaling pathway Open
The aim of the present study was to investigate the protective role of hyperoxia liquid in regulating cardiopulmonary bypass (CPB)‑induced myocardial damage and its possible underlying mechanism. In the CPB‑induced rat model, hyperoxia liq…
View article: Feed conversion ratio, residual feed intake and cholecystokinin type A receptor gene polymorphisms are associated with feed intake and average daily gain in a Chinese local chicken population
Feed conversion ratio, residual feed intake and cholecystokinin type A receptor gene polymorphisms are associated with feed intake and average daily gain in a Chinese local chicken population Open
View article: Farnesoid X receptor activation protects the kidney from ischemia-reperfusion damage
Farnesoid X receptor activation protects the kidney from ischemia-reperfusion damage Open
View article: Combination analysis of genome-wide association and transcriptome sequencing of residual feed intake in quality chickens
Combination analysis of genome-wide association and transcriptome sequencing of residual feed intake in quality chickens Open
View article: Genome-wide association study of aggressive behaviour in chicken
Genome-wide association study of aggressive behaviour in chicken Open
View article: Additional file 2: Table S2. of Combination analysis of genome-wide association and transcriptome sequencing of residual feed intake in quality chickens
Additional file 2: Table S2. of Combination analysis of genome-wide association and transcriptome sequencing of residual feed intake in quality chickens Open
GO mapping for genes within the 50Â bp flanking regions of the significant RFI-related SNPs. (XLS 31Â kb)
View article: Additional file 5: Table S4. of Combination analysis of genome-wide association and transcriptome sequencing of residual feed intake in quality chickens
Additional file 5: Table S4. of Combination analysis of genome-wide association and transcriptome sequencing of residual feed intake in quality chickens Open
Networks constructed using the differentially expressed genes predicted by IPA. (XLS 1284Â kb)
View article: Additional file 4: Table S3. of Combination analysis of genome-wide association and transcriptome sequencing of residual feed intake in quality chickens
Additional file 4: Table S3. of Combination analysis of genome-wide association and transcriptome sequencing of residual feed intake in quality chickens Open
Differentially expressed genes identified in RNA sequencing in divergent RFI individuals. (XLS 37Â kb)