Zhanwei Du
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View article: Wastewater-based epidemiology of influenza A virus in Shenzhen: baseline values and implications for multi-pathogen surveillance
Wastewater-based epidemiology of influenza A virus in Shenzhen: baseline values and implications for multi-pathogen surveillance Open
Influenza A virus (IAV) has become increasingly unpredictable in its seasonal patterns following the COVID-19 pandemic. A key challenge remains identifying optimal moments for public health interventions to inform evidence-based decisions.…
View article: Multi-spectral fusion power equipment fault recognition based on prompt learning
Multi-spectral fusion power equipment fault recognition based on prompt learning Open
To address the issue of weak fault recognition ability of power equipment in single-spectrum images, a multi-spectral fusion recognition method based on prompt learning is proposed. A multi-spectral imaging system is used to capture images…
View article: Impact of RSVpreF vaccination on reducing the burden of respiratory syncytial virus in infants and older adults
Impact of RSVpreF vaccination on reducing the burden of respiratory syncytial virus in infants and older adults Open
Respiratory syncytial virus (RSV) causes a substantial health burden among infants and older adults. Prefusion F protein-based vaccines have shown high efficacy against RSV disease in clinical trials, offering promise for mitigating this b…
View article: Epidemiological Assessment and Optimization of School-Based Influenza Vaccination — Shenzhen City, Guangdong Province, China, 2023–2024
Epidemiological Assessment and Optimization of School-Based Influenza Vaccination — Shenzhen City, Guangdong Province, China, 2023–2024 Open
The findings suggest concentrating vaccination efforts during November and December; however, optimal strategies may vary depending on specific influenza transmission patterns. A more robust approach involves implementing a generalized str…
View article: Digital-twin-based multi-scale simulation supports urban emergency management: a case study of urban epidemic transmission
Digital-twin-based multi-scale simulation supports urban emergency management: a case study of urban epidemic transmission Open
Improving emergency management capabilities is vital for sustainable cities. However, urban emergency management is a complex, giant system that interacts between urban virtual and real spaces, requiring simulation in the virtual space and…
View article: Information-guided adaptive learning approach for active surveillance of infectious diseases
Information-guided adaptive learning approach for active surveillance of infectious diseases Open
The infectious disease surveillance system is a key support tool for public health decision making. Current research concentrates on optimizing static sentinel deployment to address the problem of incomplete data due to the lack of suffici…
View article: Impact of COVID-19 control measures on respiratory syncytial virus and hand-foot-and-mouth disease transmission in Hong Kong and South Korea
Impact of COVID-19 control measures on respiratory syncytial virus and hand-foot-and-mouth disease transmission in Hong Kong and South Korea Open
The public health and social measures (PHSMs) for mitigation/control of COVID-19 pandemic influenced the transmission dynamics of many other infectious diseases, including respiratory syncytial virus (RSV) infection, and hand, foot and mou…
View article: Using pathogen genomics to predict antigenic changes of influenza H3N2 virus
Using pathogen genomics to predict antigenic changes of influenza H3N2 virus Open
Influenza viruses evolve their antigenic phenotype in response to immune-driven selection, necessitating regular updates to the antigens used in influenza vaccines. Characterising antigenic change of influenza virus currently requires inte…
View article: Editorial: Infectious Disease Epidemiology and Transmission Dynamics 2.0
Editorial: Infectious Disease Epidemiology and Transmission Dynamics 2.0 Open
This Special Issue includes six original articles and one review article, all reflecting the unified scientific research endeavors and professional expertise for a shared objective, which were published between July 2023 and November 2023 …
View article: Forecasting of influenza activity and associated hospital admission burden and estimating the impact of COVID-19 pandemic on 2019/20 winter season in Hong Kong
Forecasting of influenza activity and associated hospital admission burden and estimating the impact of COVID-19 pandemic on 2019/20 winter season in Hong Kong Open
Like other tropical and subtropical regions, influenza viruses can circulate year-round in Hong Kong. However, during the COVID-19 pandemic, there was a significant decrease in influenza activity. The objective of this study was to retrosp…
View article: Insights into COVID-19 epidemiology and control from temporal changes in serial interval distributions in Hong Kong
Insights into COVID-19 epidemiology and control from temporal changes in serial interval distributions in Hong Kong Open
The serial interval (SI) distribution of an epidemic is used to approximate the generation time distribution, an essential parameter for inferring the transmissibility (${R}_t$) of an infectious disease. However, SI distributions may chang…
View article: Predicting Efficacies of Fractional Doses of Vaccines by Using Neutralizing Antibody Levels: Systematic Review and Meta-Analysis
Predicting Efficacies of Fractional Doses of Vaccines by Using Neutralizing Antibody Levels: Systematic Review and Meta-Analysis Open
Background With the emergence of SARS-CoV-2 variants that have eluded immunity from vaccines and prior infections, vaccine shortages and vaccine effectiveness pose unprecedented challenges for governments in expanding booster vaccination p…
View article: Efficacy and safety of respiratory syncytial virus prefusion F protein vaccines in adults
Efficacy and safety of respiratory syncytial virus prefusion F protein vaccines in adults Open
•GSK and Pfizer's RSV pre-F vaccines demonstrate promising results in clinical trials of adults with encouraging efficacy.•Approval of RSV pre-F protein vaccines marks a milestone in preventing RSV illnesses in adults.•Continued research i…
View article: Global Seasonal Activities of Respiratory Syncytial Virus Before the Coronavirus Disease 2019 Pandemic: A Systematic Review
Global Seasonal Activities of Respiratory Syncytial Virus Before the Coronavirus Disease 2019 Pandemic: A Systematic Review Open
Varied seasonal patterns of respiratory syncytial virus (RSV) have been reported worldwide. We conducted a systematic review on articles identified in PubMed reporting RSV seasonality based on data collected before 1 January 2020. RSV seas…
View article: A retrospective cohort study of Paxlovid efficacy depending on treatment time in hospitalized COVID-19 patients
A retrospective cohort study of Paxlovid efficacy depending on treatment time in hospitalized COVID-19 patients Open
Paxlovid, a SARS-CoV-2 antiviral, not only prevents severe illness but also curtails viral shedding, lowering transmission risks from treated patients. By fitting a mathematical model of within-host Omicron viral dynamics to electronic hea…
View article: Public Health Impact of Paxlovid as Treatment for COVID-19, United States
Public Health Impact of Paxlovid as Treatment for COVID-19, United States Open
We evaluated the population-level benefits of expanding treatment with the antiviral drug Paxlovid (nirmatrelvir/ritonavir) in the United States for SARS-CoV-2 Omicron variant infections. Using a multiscale mathematical model, we found tha…
View article: A Systematic Review of the Definition, Measurement, and Associated Factors of Pandemic Fatigue
A Systematic Review of the Definition, Measurement, and Associated Factors of Pandemic Fatigue Open
The rapid emergence and widespread transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have prompted governments worldwide to enact policies and measures to manage the virus's spread. These interventions have subst…
View article: Perspective on the spatio-temporal spread of epidemics in metapopulation networks
Perspective on the spatio-temporal spread of epidemics in metapopulation networks Open
We review the recent progress of epidemic dynamics in metapopulation networks. Firstly, we give an introduction of the concepts about epidemic models and metapopulation network. Then, the theoretical characterization of epidemics spread in…
View article: Estimate of COVID-19 Deaths, China, December 2022–February 2023
Estimate of COVID-19 Deaths, China, December 2022–February 2023 Open
China announced a slight easing of its zero-COVID rules on November 11, 2022, and then a major relaxation on December 7, 2022. We estimate that the ensuing wave of SARS-CoV-2 infections caused 1.41 million deaths in China during December 2…
View article: International Importation Risk Estimation of SARS-CoV-2 Omicron Variant with Incomplete Mobility Data
International Importation Risk Estimation of SARS-CoV-2 Omicron Variant with Incomplete Mobility Data Open
A novel Omicron subvariant named BQ.1 emerged in Nigeria in July 2022 and has since become a dominant strain, causing a significant number of repeated infections even in countries with high-vaccination rates. Due to the high flow of people…
View article: Estimating the Importation Risk of Mpox Virus in 2022 to Hong Kong, China
Estimating the Importation Risk of Mpox Virus in 2022 to Hong Kong, China Open
International air travel has been recognized as a crucial factor in the cross-regional transmission of monkeypox (now known as mpox) since this disease rapidly spread across the globe in May 2022. On September 6, 2022, Hong Kong SAR (HK) r…
View article: Multimodeling approach to evaluating the efficacy of layering pharmaceutical and nonpharmaceutical interventions for influenza pandemics
Multimodeling approach to evaluating the efficacy of layering pharmaceutical and nonpharmaceutical interventions for influenza pandemics Open
When an influenza pandemic emerges, temporary school closures and antiviral treatment may slow virus spread, reduce the overall disease burden, and provide time for vaccine development, distribution, and administration while keeping a larg…
View article: Protocol for the automatic extraction of epidemiological information via a pre-trained language model
Protocol for the automatic extraction of epidemiological information via a pre-trained language model Open
The lack of systems to automatically extract epidemiological fields from open-access COVID-19 cases restricts the timeliness of formulating prevention measures. Here we present a protocol for using CCIE, a COVID-19 Cases Information Extrac…