Fu Zhang
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View article: Independent association of lung injury with lactate after pulmonary vascular intervention: a cross-sectional study
Independent association of lung injury with lactate after pulmonary vascular intervention: a cross-sectional study Open
Background Postoperative hyperlactatemia is associated with organ dysfunction, but its independent role in lung injury remains underexplored, particularly relative to pulmonary hemodynamics. Objective To determine whether postoperative lac…
View article: Association between joint physical activity and alcohol intake and all-cause mortality in patients with cardiovascular disease: findings from NHANES 2007–2018
Association between joint physical activity and alcohol intake and all-cause mortality in patients with cardiovascular disease: findings from NHANES 2007–2018 Open
Background Physical activity and alcohol consumption are both highly prevalent in many countries, while the evidence related to joint effect on physical activity and alcohol consumption on patients with cardiovascular disease (CVD) was sti…
View article: Association between occurrence time of myocardial injury after noncardiac surgery and long-term functional capacity: a secondary analysis of a prospective study
Association between occurrence time of myocardial injury after noncardiac surgery and long-term functional capacity: a secondary analysis of a prospective study Open
MINS occurring after 24 h was associated with worsen long-term functional capacity after surgery, whereas MINS occurring within 24 h was not.
View article: Identification and validation of core microbes for isoflavone conversion and flavor formation in fermented sojae semen praeparatum
Identification and validation of core microbes for isoflavone conversion and flavor formation in fermented sojae semen praeparatum Open
View article: Integrated transcriptomics and metabolomics confirms the oxidative stress mechanism of hypothermia-induced neuronal necroptosis
Integrated transcriptomics and metabolomics confirms the oxidative stress mechanism of hypothermia-induced neuronal necroptosis Open
View article: Correlation analysis between clinical characteristics of adult patients with Mycoplasma pneumoniae pneumonia and 23S rRNA A2063 gene in alveolar lavage fluid
Correlation analysis between clinical characteristics of adult patients with Mycoplasma pneumoniae pneumonia and 23S rRNA A2063 gene in alveolar lavage fluid Open
Adults with MPP with 23S rRNA A2063G drug resistance gene mutation have more severe clinical presentations, higher serum fibrinogen levels and a greater incidence of extrapulmonary complications. Serum fibrinogen levels and imaging signs o…
View article: Synergistic Effect of Charge-Transfer Bridge and Surface Defects for Highly Efficient Photothermal Catalytic Co2 Reduction Over 2d/3d Srtio3/Zn0.5cd0.5s
Synergistic Effect of Charge-Transfer Bridge and Surface Defects for Highly Efficient Photothermal Catalytic Co2 Reduction Over 2d/3d Srtio3/Zn0.5cd0.5s Open
View article: Rational Design of the Oriented Photogenerated Electron Flow Interface in S-Scheme Cd0.5zn0.5s/Mos2 Heterojunction for Efficient Visible-Light-Driven Photothermal Catalytic Co2 Reduction
Rational Design of the Oriented Photogenerated Electron Flow Interface in S-Scheme Cd0.5zn0.5s/Mos2 Heterojunction for Efficient Visible-Light-Driven Photothermal Catalytic Co2 Reduction Open
View article: Self-assembled aldehyde dehydrogenase-activatable nano-prodrug for cancer stem cell-enriched tumor detection and treatment
Self-assembled aldehyde dehydrogenase-activatable nano-prodrug for cancer stem cell-enriched tumor detection and treatment Open
Cancer stem cells, characterized by high tumorigenicity and drug-resistance, are often responsible for tumor progression and metastasis. Aldehyde dehydrogenases, often overexpressed in cancer stem cells enriched tumors, present a potential…
View article: Incidence and predictors of in-stent restenosis following intervention for pulmonary vein stenosis due to fibrosing mediastinitis
Incidence and predictors of in-stent restenosis following intervention for pulmonary vein stenosis due to fibrosing mediastinitis Open
View article: Analysis on the Current Situation and Countermeasures of Cultivating New Vocational Farmers in Tianjin
Analysis on the Current Situation and Countermeasures of Cultivating New Vocational Farmers in Tianjin Open
The rural revitalization strategy requires strengthening the construction of rural talent teams, proposing to implement the cultivation plan for new vocational farmers, and carrying out the cultivation action for rural entrepreneurial lead…
View article: Self-assembled Aldehyde Dehydrogenase-Activatable Nano-prodrug for Cancer Stem Cell-Enriched Tumor Detection and Treatment
Self-assembled Aldehyde Dehydrogenase-Activatable Nano-prodrug for Cancer Stem Cell-Enriched Tumor Detection and Treatment Open
Cancer stem cells (CSCs), characterized by high tumorigenicity and drug-resistance, are often responsible for tumor progression and metastasis. Aldehyde dehydrogenases (ALDH), often overexpressed in CSC-enriched tumors, present a potential…
View article: Microbiota profiling reveals alteration of gut microbial neurotransmitters in a mouse model of autism-associated 16p11.2 microduplication
Microbiota profiling reveals alteration of gut microbial neurotransmitters in a mouse model of autism-associated 16p11.2 microduplication Open
The gut-brain axis is evident in modulating neuropsychiatric diseases including autism spectrum disorder (ASD). Chromosomal 16p11.2 microduplication 16p11.2 dp/+ is among the most prevalent genetic copy number variations (CNV) linked with …
View article: Progress in the Use of Echocardiography in Patients with Tumors
Progress in the Use of Echocardiography in Patients with Tumors Open
Advances in cancer treatment have increased patient survival rates, shifting clinical focus towards minimizing treatment-related morbidity, including cardiovascular issues. Since echocardiography allows for a comprehensive non-invasive ass…
View article: Incidence and Predictors of In-stent Restenosis Following Intervention for Pulmonary Vein Stenosis due to Fibrosing Mediastinitis
Incidence and Predictors of In-stent Restenosis Following Intervention for Pulmonary Vein Stenosis due to Fibrosing Mediastinitis Open
Background Percutaneous transluminal pulmonary venoplasty (PTPV) is an emerging treatment for pulmonary vein stenosis (PVS) caused by fibrosing mediastinitis (FM). However, the incidence and predictors of in-stent restenosis (ISR) are elus…
View article: The amino acid metabolomics signature of differentiating myocardial infarction from strangulation death in mice models
The amino acid metabolomics signature of differentiating myocardial infarction from strangulation death in mice models Open
View article: Exosomal circEZH2_005, an intestinal injury biomarker, alleviates intestinal ischemia/reperfusion injury by mediating Gprc5a signaling
Exosomal circEZH2_005, an intestinal injury biomarker, alleviates intestinal ischemia/reperfusion injury by mediating Gprc5a signaling Open
Intestinal ischemia/reperfusion (I/R) injury is a severe clinical condition without optimal diagnostic markers nor clear molecular etiological insights. Plasma exosomal circular RNAs (circRNAs) are valuable biomarkers and therapeutic targe…
View article: Pulmonary fat embolism: a potentially new fatal complication of SARS-CoV-2 infection. A case report
Pulmonary fat embolism: a potentially new fatal complication of SARS-CoV-2 infection. A case report Open
View article: Combination therapy to overcome ferroptosis resistance by biomimetic self-assembly nano-prodrug
Combination therapy to overcome ferroptosis resistance by biomimetic self-assembly nano-prodrug Open
View article: A novel allatostatin-A analog, III-2 may particularly regulates juvenile hormone III to influence Spodoptera frugiperda metamorphosis and development
A novel allatostatin-A analog, III-2 may particularly regulates juvenile hormone III to influence Spodoptera frugiperda metamorphosis and development Open
Allatostatin (AST) is a class of insect neuropeptides that affects insect growth and development by inhibiting the synthesis of juvenile hormones (JH) in different insects. Ⅲ-2 is a novel allatostatin-A（AST-A）analog derived from a class of…
View article: Changes in Intestinal Flora Diversity and Intestinal Immune Barrier in Patients with Ulcerative Colitis
Changes in Intestinal Flora Diversity and Intestinal Immune Barrier in Patients with Ulcerative Colitis Open
The objective of this study was to analyze the changes of intestinal flora diversity and intestinal immune barrier in patients with ulcerative colitis (UC).The present study included 58 UC patients admitted to the Department of Gastroenter…
View article: Triple‐Combination Immunogenic Nanovesicles Reshape the Tumor Microenvironment to Potentiate Chemo‐Immunotherapy in Preclinical Cancer Models
Triple‐Combination Immunogenic Nanovesicles Reshape the Tumor Microenvironment to Potentiate Chemo‐Immunotherapy in Preclinical Cancer Models Open
Immune checkpoint blockade (ICB) therapies have had a tremendous impact on cancer therapy. However, most patients harbor a poorly immunogenic tumor microenvironment (TME), presenting overwhelming de novo refractoriness to ICB inhibitors. T…
View article: Differences in Cardiac Rupture and Hemopericardium Caused by Blunt Chest Injury, Acute Myocardial Infarct, Aortic Dissection and CPR
Differences in Cardiac Rupture and Hemopericardium Caused by Blunt Chest Injury, Acute Myocardial Infarct, Aortic Dissection and CPR Open
Objective In this study, the hemopericardium volume and pathological characteristics associated with cardiac ruptures caused by blunt violence, AMI, aortic dissection and CPR have been analyzed. The findings might provide reference and dat…
View article: Sudden unexpected death in epilepsy: Investigation of autopsy-based studies
Sudden unexpected death in epilepsy: Investigation of autopsy-based studies Open
Epilepsy is a common neurological disorder that is associated with increased morbidity and mortality. Sudden unexpected death in epilepsy (SUDEP) is one of the most common causes for epilepsy-related deaths and its characteristics remain l…
View article: An Ionic Liquid Ablation Agent for Local Ablation and Immune Activation in Pancreatic Cancer
An Ionic Liquid Ablation Agent for Local Ablation and Immune Activation in Pancreatic Cancer Open
Pancreatic ductal adenocarcinoma rapidly acquires resistance to chemotherapy, remaining a fatal disease. Immunotherapy is one of the breakthroughs in cancer treatment, which includes immune checkpoint inhibitors, chimeric antigen receptor …
View article: Exosomal circEZH2_005, an intestinal injury biomarker, alleviates intestinal ischemia/reperfusion injury by mediating hnRNPA1/Gprc5a signaling
Exosomal circEZH2_005, an intestinal injury biomarker, alleviates intestinal ischemia/reperfusion injury by mediating hnRNPA1/Gprc5a signaling Open
Intestinal ischemia/reperfusion (I/R) injury is a severe clinical condition lacking diagnostic markers and has poorly understood molecular mechanisms. Although plasma exosomal circular RNAs (circRNAs) are valuable biomarkers and therapeuti…
View article: Additional file 5 of Analysis of gut microbiota diversity in Hashimoto’s thyroiditis patients
Additional file 5 of Analysis of gut microbiota diversity in Hashimoto’s thyroiditis patients Open
Additional file 5.
View article: Analysis of gut microbiota diversity in Hashimoto’s thyroiditis patients
Analysis of gut microbiota diversity in Hashimoto’s thyroiditis patients Open
Background Hashimoto’s thyroiditis (HT) is an autoimmune disease. Recent studies have found that the gut microbiota may play an important role in inducing HT, but there are no systematic studies on the changes in the gut microbiota during …
View article: Peripheral interleukin-6-associated microglial QUIN elevation in basolateral amygdala contributed to cognitive dysfunction in a mouse model of postoperative delirium
Peripheral interleukin-6-associated microglial QUIN elevation in basolateral amygdala contributed to cognitive dysfunction in a mouse model of postoperative delirium Open
Background Developing effective approaches for postoperative delirium has been hampered due to the lack of a pathophysiologically similar animal model to offer insights into the pathogenesis. The study, therefore, aimed to develop a deliri…
View article: Sudden Cardiac Death in Schizophrenia During Hospitalization: An Autopsy-Based Study
Sudden Cardiac Death in Schizophrenia During Hospitalization: An Autopsy-Based Study Open
Schizophrenia is a severe mental disorder that is often comorbid with heart dysfunction and even sudden cardiac death (SCD). Clinical studies of SCD in schizophrenia have been largely reported, while there are limited autopsy studies that …