Yihong Zhang
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View article: Multiomic insights into the MPO-mediated NET formation pathway in alcohol-induced epilepsy risk
Multiomic insights into the MPO-mediated NET formation pathway in alcohol-induced epilepsy risk Open
View article: Early Prosthodontic Intervention For Hed-Associated Congenital Anodontia
Early Prosthodontic Intervention For Hed-Associated Congenital Anodontia Open
Introduction: This report details the diagnostic and therapeutic management of a male infant with hypohidrotic ectodermal dysplasia (HED)-induced congenital anodontia. Case description: A male child born on November 16, 2020, was diagnosed…
View article: Association between imaging-derived fat distribution and stress urinary incontinence: a cross-sectional study in US adult women
Association between imaging-derived fat distribution and stress urinary incontinence: a cross-sectional study in US adult women Open
There was a non-linear relationship between the A/G ratio and SUI. In individuals with a lower A/G ratio, even small increases in the A/G ratio substantially elevated the risk of SUI. Results of this study indicate that A/G ratio, as a mea…
View article: Switching Cathodic/Anodic Electrochemiluminescence of Ru(bpy) <sub>3</sub> <sup>2+</sup> Precisely via Homogeneous Nickel Nanoparticles Crystal Facets Sites Modulated ORR/OER
Switching Cathodic/Anodic Electrochemiluminescence of Ru(bpy) <sub>3</sub> <sup>2+</sup> Precisely via Homogeneous Nickel Nanoparticles Crystal Facets Sites Modulated ORR/OER Open
Reactive oxygen species (ROS) have gained increasing attention in electrochemiluminescence (ECL) as endogenous co‐reactants, yet their application in the most widely used tris(bipyridine)‐ruthenium(II) system remains limited due to the sca…
View article: Barging along the Conflitual Line Between Protocals and Practicals: Autonomous Driving Solution Between Chinese Manufacturers and Tesla
Barging along the Conflitual Line Between Protocals and Practicals: Autonomous Driving Solution Between Chinese Manufacturers and Tesla Open
This paper explores the technological underpinnings and regulatory challenges of autonomous driving systems in New Energy Vehicles (NEVs), with a focus on three core components: electric control systems, electric motors, and batteries. By …
View article: Deletion of SH2D5 alleviates epileptic seizures and NMDAR expression via autophagic degradation of STAT1
Deletion of SH2D5 alleviates epileptic seizures and NMDAR expression via autophagic degradation of STAT1 Open
Epilepsy is a common neurological disorder resulting from an imbalance between neuronal excitation and inhibition. Synapses play a pivotal role in the pathogenesis of epilepsy. Src-homology 2 (SH2) domain-containing protein 5 (SH2D5) is hi…
View article: Probiotics restore enteric HDL3 secretion and improve prognosis in patients with end‐stage renal disease
Probiotics restore enteric HDL3 secretion and improve prognosis in patients with end‐stage renal disease Open
Randomized double-blind trials have shown that probiotic mixtures significantly increase high-density lipoprotein (HDL) levels and reduce the risk of cardiovascular disease mortality in end-stage renal disease (ESRD) patients. Meta-analysi…
View article: Next-generation probiotics and engineered BEVs for precision therapeutics in osteoporosis
Next-generation probiotics and engineered BEVs for precision therapeutics in osteoporosis Open
Osteoporosis, characterized by reduced bone density and increased fracture risk, faces limitations with conventional therapies due to adverse effects and poor gut microbiota modulation. Emerging strategies leveraging probiotics and bacteri…
View article: Effectiveness evaluation of connected and automated vehicles’ driving loop: Node weights and driving reliability
Effectiveness evaluation of connected and automated vehicles’ driving loop: Node weights and driving reliability Open
As an emerging development trend in the automotive industry, the construction of the network model and the effectiveness evaluation of the driving loop for Connected and Automated Vehicles (CAVs) are of significant importance. The objectiv…
View article: Garsorasib, a KRAS G12C inhibitor, with or without cetuximab, an EGFR antibody, in colorectal cancer cohorts of a phase II trial in advanced solid tumors with KRAS G12C mutation
Garsorasib, a KRAS G12C inhibitor, with or without cetuximab, an EGFR antibody, in colorectal cancer cohorts of a phase II trial in advanced solid tumors with KRAS G12C mutation Open
Mutations in the KRAS gene have long been implicated in the pathogenesis of colorectal cancer (CRC). KRAS G12C inhibitors overcome the “undruggable” challenge, enabling precision therapy. Garsorasib (D-1553), a highly potent and selective …
View article: IGF2BP3 enhances ferroptosis resistance in colon cancer by stabilizing SLC7A11 and is regulated by miR-98-5p
IGF2BP3 enhances ferroptosis resistance in colon cancer by stabilizing SLC7A11 and is regulated by miR-98-5p Open
Purpose Colon cancer remains a global health challenge with rising mortality, necessitating novel therapeutic strategies. IGF2BP3, an oncogenic RNA-binding protein, is implicated in colon cancer progression, while its role in ferroptosis r…
View article: Research on driver injuries in vehicle rear-end collisions considering different overlap rate and speed difference
Research on driver injuries in vehicle rear-end collisions considering different overlap rate and speed difference Open
Rear-end collisions involving passenger vehicles often result in significant injuries and fatalities, with the driver of the trailing vehicle being particularly vulnerable to severe harm. This study analyzes regulations related to rear-end…
View article: Effects of acute exercise programs on heart rate variability and vascular function in sedentary college students: A randomized controlled trial
Effects of acute exercise programs on heart rate variability and vascular function in sedentary college students: A randomized controlled trial Open
Background: The specific effects of different exercises on cardiovascular health remain unclear. This study aimed to compare the effects of acute anaerobic threshold intensity continuous exercise (ATE), high-intensity interval training (HI…
View article: Dilemmas and Opportunities for Chinese Broadcasters and Presenters in the Era of Media Convergence
Dilemmas and Opportunities for Chinese Broadcasters and Presenters in the Era of Media Convergence Open
In this era of media convergence with rapid technological development, broadcasting practitioners are faced with the problem of how to use new technologies to enhance news dissemination and turn dilemmas into opportunities. This study uses…
View article: Carbon management in massive electric vehicle temporal and spatial scheduling with automotive electronic forensics
Carbon management in massive electric vehicle temporal and spatial scheduling with automotive electronic forensics Open
Electric vehicles (EVs) provide an environmentally friendly solution to reduce reliance on fossil fuels. However, increasing EV adoption and distributed solar generation pose new challenges for power systems, such as increased load variabi…
View article: Heart Failure and Arrhythmias: Circadian and Epigenetic Interplay in Myocardial Electrophysiology
Heart Failure and Arrhythmias: Circadian and Epigenetic Interplay in Myocardial Electrophysiology Open
Emerging evidence underscores the impact of circadian rhythms on cardiovascular processes, particularly in conditions such as hypertension, myocardial infarction, and heart failure, where circadian rhythm disruptions are linked to disease …
View article: <i>Diaphorina citri</i> E3 ubiquitin ligase RNF115 inhibits <i>C</i>Las bacterial proliferation by targeting to the host histone H1
<i>Diaphorina citri</i> E3 ubiquitin ligase RNF115 inhibits <i>C</i>Las bacterial proliferation by targeting to the host histone H1 Open
The Asian citrus psyllid (ACP), Diaphorina citri , serves as the primary vector for Candidatus Liberibacter asiaticus ( C Las), the pathogen responsible for citrus Huanglongbing (HLB). D. citri modulates the expression of its key proteins …
View article: Erythematous Neck Folds in Infant
Erythematous Neck Folds in Infant Open
View article: A Review of the Application of Hemispherical Photography in Urban Outdoor Thermal Comfort Studies
A Review of the Application of Hemispherical Photography in Urban Outdoor Thermal Comfort Studies Open
Thermal comfort studies are paramount in enhancing future urban living conditions, and hemispherical photography has emerged as a widely employed field measurement technique in outdoor thermal comfort research. This comprehensive review sy…
View article: Research on Standard System in Energy Field Based on BIM Intelligent Construction
Research on Standard System in Energy Field Based on BIM Intelligent Construction Open
View article: Histone deacetylase in inflammatory bowel disease: novel insights
Histone deacetylase in inflammatory bowel disease: novel insights Open
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is characterized by chronic nonspecific intestinal inflammation. Despite considerable efforts, IBD remains a heavy burden on society and human health, with…
View article: Can the "Braking" of Land Finance Promote Educational Equity?— Evidence from China's New Budget Law
Can the "Braking" of Land Finance Promote Educational Equity?— Evidence from China's New Budget Law Open
View article: Microenvironmental modulation breaks intrinsic pH limitations of nanozymes to boost their activities
Microenvironmental modulation breaks intrinsic pH limitations of nanozymes to boost their activities Open
Functional nanomaterials with enzyme-mimicking activities, termed as nanozymes, have found wide applications in various fields. However, the deviation between the working and optimal pHs of nanozymes has been limiting their practical appli…
View article: Stereoselective block of the hERG potassium channel by the Class Ia antiarrhythmic drug disopyramide
Stereoselective block of the hERG potassium channel by the Class Ia antiarrhythmic drug disopyramide Open
View article: Copper depletion-induced tumor cuproptosis
Copper depletion-induced tumor cuproptosis Open
Copper accumulated-cuproptosis has been extensively investigated, copper depleted-cuproptosis remains largely unexplored. Based on the solubility product principle, a novel copper depletion-induced tumor cuproptosis strategy was developed.
View article: The Impact of Economic Growth and Foreign Investment on the Advancement of E-commerce
The Impact of Economic Growth and Foreign Investment on the Advancement of E-commerce Open
This study examines the interrelationship between economic growth, foreign investment, and e-commerce development in Kyrgyzstan from 2010 to 2022. Using correlation and regression analyses, the research reveals a strong positive relationsh…
View article: The synthesis, characterization, and thermal properties of a titanium (III) amidinate compound and its potential as a single chemical vapor deposition precursor for N/C-doped TiO2 film
The synthesis, characterization, and thermal properties of a titanium (III) amidinate compound and its potential as a single chemical vapor deposition precursor for N/C-doped TiO2 film Open
A titanium(III) amidinate compound had been successfully obtained using a salt elimination reaction between TiCl3(3THF) and [Li(i Prn BuAMD)] in a 65% yield, and the characterization of the compound was conducted using various characteriza…
View article: E-Graphs as Circuits, and Optimal Extraction via Treewidth
E-Graphs as Circuits, and Optimal Extraction via Treewidth Open
We demonstrate a new connection between e-graphs and Boolean circuits. This allows us to adapt existing literature on circuits to easily arrive at an algorithm for optimal e-graph extraction, parameterized by treewidth, which runs in $2^{O…
View article: Differential effects of exercise and hormone treatment on spinal cord injury-induced changes in micturition and morphology of external urethral sphincter motoneurons
Differential effects of exercise and hormone treatment on spinal cord injury-induced changes in micturition and morphology of external urethral sphincter motoneurons Open
Background: Spinal cord injury (SCI) results in lesions that destroy tissue and spinal tracts, leading to deficits in locomotor and autonomic function. We have previously shown that after SCI, surviving motoneurons innervating hindlimb mus…
View article: Stereoselective block of the hERG potassium channel by the Class Ia antiarrhythmic drug disopyramide.
Stereoselective block of the hERG potassium channel by the Class Ia antiarrhythmic drug disopyramide. Open
Potassium channels encoded by human Ether-à-go-go-Related Gene (hERG) are inhibited by diverse cardiac and non-cardiac drugs. Disopyramide is a chiral Class Ia antiarrhythmic that inhibits hERG at clinical concentrations. This study evalua…