Zhangqian Wang
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View article: <scp>BRACO</scp>‐19 targeted the G‐quadruplex in the 3<scp>′UTR</scp> of the <i>Cucumber mosaic virus 1a</i>, <i>2b</i>, and <i>CP</i> genes to inhibit viral proliferation
<span>BRACO</span>‐19 targeted the G‐quadruplex in the 3<span>′UTR</span> of the <i>Cucumber mosaic virus 1a</i>, <i>2b</i>, and <i>CP</i> genes to inhibit viral proliferation Open
Background The development of highly efficient and environmentally friendly plant virus inhibitors with novel structures mostly depends on the discovery of new targets. G‐quadruplexes are non‐classical high‐level structures that are formed…
View article: Biosynthesis of Potential Inhibitors Against Tobacco Mosaic Virus by Bacillus Licheniformis T6: L-Cysteine-Functionalized Selenium Nanoparticles
Biosynthesis of Potential Inhibitors Against Tobacco Mosaic Virus by Bacillus Licheniformis T6: L-Cysteine-Functionalized Selenium Nanoparticles Open
View article: Optimization of fermentation parameters to improve the biosynthesis of selenium nanoparticles by Bacillus licheniformis F1 and its comprehensive application
Optimization of fermentation parameters to improve the biosynthesis of selenium nanoparticles by Bacillus licheniformis F1 and its comprehensive application Open
Background Selenium nanoparticles (SeNPs) are increasingly gaining attention due to its characteristics of low toxicity, high activity, and stability. Additionally, Bacillus licheniformis , as a probiotic, has achieved remarkable research …
View article: Effect of Different Selenium Species on Indole-3-Acetic Acid Activity of Selenium Nanoparticles Producing Strain Bacillus altitudinis LH18
Effect of Different Selenium Species on Indole-3-Acetic Acid Activity of Selenium Nanoparticles Producing Strain Bacillus altitudinis LH18 Open
Acting as a growth regulator, Indole-3-acetic acid (IAA) is an important phytohormone that can be produced by several Bacillus species. However, few studies have been published on the comprehensive evaluation of the strains for practical a…
View article: Effects of Molecular Crowding on the Structure, Stability, and Interaction with Ligands of G-quadruplexes
Effects of Molecular Crowding on the Structure, Stability, and Interaction with Ligands of G-quadruplexes Open
G-quadruplexes (G4s) are widely found in cells and have significant biological functions, which makes them a target for screening antitumor and antiviral drugs. Most of the previous research on G4s has been conducted mainly in diluted solu…
View article: Insect multimeric G-quadruplexes fold into antiparallel structures of different compactness and stability in K <sup>+</sup> and Na <sup>+</sup> solutions
Insect multimeric G-quadruplexes fold into antiparallel structures of different compactness and stability in K <sup>+</sup> and Na <sup>+</sup> solutions Open
Insect telomeric G-quadruplexes have a more compact and stable structure in Na + solutions, and have a different binding pattern to ligand BMPQ-1 in K + and Na + solutions.
View article: Highly Efficient Biotransformation and Production of Selenium Nanoparticles and Polysaccharides Using Potential Probiotic Bacillus subtilis T5
Highly Efficient Biotransformation and Production of Selenium Nanoparticles and Polysaccharides Using Potential Probiotic Bacillus subtilis T5 Open
Selenium is an essential microelement required for human health. The biotransformation of selenium nanoparticles has attracted increasing attention in recent years. However, little of the literature has investigated the comprehensive evalu…
View article: Minimization and optimization of α-amylase terminator for heterologous protein production in Bacillus licheniformis
Minimization and optimization of α-amylase terminator for heterologous protein production in Bacillus licheniformis Open
View article: Enhancing the Activity of Carboxymethyl Cellulase Enzyme Using Highly Stable Selenium Nanoparticles Biosynthesized by Bacillus paralicheniformis Y4
Enhancing the Activity of Carboxymethyl Cellulase Enzyme Using Highly Stable Selenium Nanoparticles Biosynthesized by Bacillus paralicheniformis Y4 Open
The inorganic selenium is absorbed and utilized inefficiently, and the range between toxicity and demand is narrow, so the application is strictly limited. Selenium nanoparticles have higher bioactivity and biosafety properties, including …
View article: RHPS4 shifted the conformation ensemble equilibrium of Tel24 by preferentially stabilizing the (3 + 1) hybrid-2 conformation
RHPS4 shifted the conformation ensemble equilibrium of Tel24 by preferentially stabilizing the (3 + 1) hybrid-2 conformation Open
Tel24 G-quadruplex can form a conformational ensemble consisting of parallel and (3 + 1) hybrid-2 conformations. RHPS4 preferentially stabilized the hybrid-2 conformation and shifted the conformational ensemble equilibrium.
View article: Microbe Engineering of Guaia-6,10(14)-diene as a Building Block for the Semisynthetic Production of Plant-Derived (−)-Englerin A
Microbe Engineering of Guaia-6,10(14)-diene as a Building Block for the Semisynthetic Production of Plant-Derived (−)-Englerin A Open
Herein, we report the semisynthetic production of the potent transient receptor potential canonical (TRPC) channel agonist (−)-englerin A (EA), using guaia-6,10(14)-diene as the starting material. Guaia-6,10(14)-diene was systematically en…
View article: Microbe Engineering of Guaia-6,10(14)-diene as a Building Block for the Semisynthetic Production of Plant-Derived (−)-Englerin A
Microbe Engineering of Guaia-6,10(14)-diene as a Building Block for the Semisynthetic Production of Plant-Derived (−)-Englerin A Open
Herein, we report the semisynthetic production of the potent transient receptor potential canonical (TRPC) channel agonist (−)-englerin A (EA), using guaia-6,10(14)-diene as the starting material. Guaia-6,10(14)-diene was systematically en…
View article: Toxicity and possible mechanisms of action of honokiol from Magnolia denudata seeds against four mosquito species
Toxicity and possible mechanisms of action of honokiol from Magnolia denudata seeds against four mosquito species Open
This study was performed to determine the toxicity and possible mechanism of the larvicidal action of honokiol, extracted from Magnolia denudata seeds, and its 10 related compounds against third-instar larvae of insecticide-susceptible Cul…
View article: Development of an Efficient Genome Editing Tool in Bacillus licheniformis Using CRISPR-Cas9 Nickase
Development of an Efficient Genome Editing Tool in Bacillus licheniformis Using CRISPR-Cas9 Nickase Open
Bacillus strains are important industrial bacteria that can produce various biochemical products. However, low transformation efficiencies and a lack of effective genome editing tools have hindered its widespread application. Recently, clu…
View article: Expression and functional analysis of the lysine decarboxylase and copper amine oxidase genes from the endophytic fungus Colletotrichum gloeosporioides ES026
Expression and functional analysis of the lysine decarboxylase and copper amine oxidase genes from the endophytic fungus Colletotrichum gloeosporioides ES026 Open
View article: Larvicidal activity of <i>Magnolia denudata</i> seed hydrodistillate constituents and related compounds and liquid formulations towards two susceptible and two wild mosquito species
Larvicidal activity of <i>Magnolia denudata</i> seed hydrodistillate constituents and related compounds and liquid formulations towards two susceptible and two wild mosquito species Open
BACKGROUND Anopheles sinensis , Aedes aegypti and Aedes albopictus and Culex pipiens pallens mosquitoes transmit malaria, dengue fever and West Nile virus diseases respectively. This study was conducted to determine the toxicity of 17 cons…