Zhang‐Xin Yu
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View article: Studies on the Chemical Constituents from the Seeds of Noni and Their Anti-inflammatory Bioactivity
Studies on the Chemical Constituents from the Seeds of Noni and Their Anti-inflammatory Bioactivity Open
View article: Studies on the Highly Oxidized Cadinane Sesquiterpenes from <i>Alangium salviifolium</i> and Their Bioactivities
Studies on the Highly Oxidized Cadinane Sesquiterpenes from <i>Alangium salviifolium</i> and Their Bioactivities Open
a,b 陈光英 * ,a,b ( a 海南师范大学 热带药用资源化学教育部重点实验室 海口 571158) ( b 海南师范大学化学与化工学院 海南省热带药用植物化学重点实验室 海口 571158) 摘要 从海南民间药用植物土坛树树皮中分离得到 2 个新的高度氧化的杜松烷型倍半萜类化合物 alansalene A (1)和 2,7-二羟基-4-异丙基-1-甲基-6-萘醛(5)以及 5 个已知的同系物, 通过 NMR、HR-ESI-MS 等多种现代波谱技术确定了其 化学结构.…
View article: Anti-Inflammatory Diterpenoids from the Aerial Parts of Leucas Zeylanica
Anti-Inflammatory Diterpenoids from the Aerial Parts of Leucas Zeylanica Open
View article: Two New Labdane Diterpenoids from the Leaves of <i>Callicarpa nudiflora</i>
Two New Labdane Diterpenoids from the Leaves of <i>Callicarpa nudiflora</i> Open
a 海南师范大学化学与化工学院 热带药用资源化学教育部重点实验室 热带药用植物化学海南省重点实验室 海口 571158) ( b 海南科技职业大学 药食同源植物资源海南省重点实验室 海口 571126) 摘要 从裸花紫珠叶子中分离纯化得到 2 个新的半日花烷型二萜化合物 3-氧代-7-羟基-半日花烷-8(17),13E-烯-15-酸 (1)、3-氧代-8-羟基-半日花烷-13E-烯-15-酸(2)及 5 个已知的萜类化合物, 其结构通过核磁共振(NMR)、高分辨电喷雾电 离…
View article: Callnudoids A–H: Highly modified labdane diterpenoids with anti-inflammation from the leaves of Callicarpa nudiflora
Callnudoids A–H: Highly modified labdane diterpenoids with anti-inflammation from the leaves of Callicarpa nudiflora Open
View article: [Establishment and comparison of three human multiple myeloma cell line transplantation models in mice].
[Establishment and comparison of three human multiple myeloma cell line transplantation models in mice]. Open
Objective: To establish three types of xenotransplantation models using human myeloma cell lines ARP1, MM.1S, and NCI-H929 and to compare the proliferation, tumor load, and biological characteristics of the three types of cells afte…
View article: Two New Kojic Acids from <i>Noni</i> Juice with Glucose Uptake Activity in Insulin-Resistant HepG2 Cells
Two New Kojic Acids from <i>Noni</i> Juice with Glucose Uptake Activity in Insulin-Resistant HepG2 Cells Open
HepG2 细胞的葡萄糖摄取, 从而改善胰岛素抵抗.
View article: Remarkable Phytochemical Characteristics of Chi-Nan Agarwood Induced from New-Found Chi-Nan Germplasm of Aquilaria sinensis Compared with Ordinary Agarwood
Remarkable Phytochemical Characteristics of Chi-Nan Agarwood Induced from New-Found Chi-Nan Germplasm of Aquilaria sinensis Compared with Ordinary Agarwood Open
Wild Chi-Nan agarwood is regarded as the highest quality agarwood from Aquilaria spp. However, the comprehensive research on chemical composition of wild Chi-Nan agarwood is limited. An integrated strategy using SHS-GC-MS and UPLC-Q/Tof-MS…
View article: Two New Phenolic Derivatives with<i>α-</i>Glucosidase Inhibitory Activities from<i>Noni Juice</i>
Two New Phenolic Derivatives with<i>α-</i>Glucosidase Inhibitory Activities from<i>Noni Juice</i> Open
View article: Chemical Constituents and Biological Functions of Different Extracts of <i>Millettia speciosa </i>Leaves
Chemical Constituents and Biological Functions of Different Extracts of <i>Millettia speciosa </i>Leaves Open
Millettia speciosa, a traditional Chinese folk medicine, used as immunity enhancer and anti-bronchitis. The study was proposed to investigate phytocomponents and pharmacological activities (antityrosinase, sunscreen and anticancer) of the …
View article: Endophytes of Terrestrial Plants: A Potential Source of Bioactive Secondary Metabolites
Endophytes of Terrestrial Plants: A Potential Source of Bioactive Secondary Metabolites Open
Endophytes are plant inhabiting microorganisms that possess a big and untapped source of natural products with unique chemical structures and biological activities for pharmaceutical and agriculture industry. About, several hundred of endo…
View article: Chemical Constituents and Anti-Inflammatory Effect of Incense Smoke from Agarwood Determined by GC-MS
Chemical Constituents and Anti-Inflammatory Effect of Incense Smoke from Agarwood Determined by GC-MS Open
Agarwood is generally used to make incense sticks in China and Southeast Asia. It emits smoke with a pleasant odor when burned. There are few reports on the chemical components of smoke generated by burning or heating agarwood. The agarwoo…
View article: Agarwood Alcohol Extract Ameliorates Isoproterenol-Induced Myocardial Ischemia by Inhibiting Oxidation and Apoptosis
Agarwood Alcohol Extract Ameliorates Isoproterenol-Induced Myocardial Ischemia by Inhibiting Oxidation and Apoptosis Open
Agarwood is a traditional medicine used for treating some diseases, including painful and ischemic diseases. This study was carried out to investigate the potential cardioprotective effect of the whole-tree agarwood-inducing technique-prod…
View article: Agarwood Extract Mitigates Intestinal Injury in Fluorouracil-Induced Mice
Agarwood Extract Mitigates Intestinal Injury in Fluorouracil-Induced Mice Open
Agarwood is used to treat gastrointestinal diseases. Although our previous studies demonstrated that agarwood ethanol extract produced by the whole-tree agarwood-inducing technique (WTAAE) improves intestinal peristalsis, the intestinal pr…
View article: PF575 OVEREXPRESSION DNP73 PROMOTES THE PROLIFERATION AND DRUG RESISTANCE OF MULTIPLE MYELOMA
PF575 OVEREXPRESSION DNP73 PROMOTES THE PROLIFERATION AND DRUG RESISTANCE OF MULTIPLE MYELOMA Open
Background: Genomic instability and chromosomal abnormalities induced by DNA damage are important biological characteristics of multiple myeloma (MM). DNp73 is one of the main isomers of TP73, a member of the TP53 protein family. We found …
View article: New 2-(2-phenylethyl)chromone derivatives from agarwood and their inhibitory effects on tumor cells
New 2-(2-phenylethyl)chromone derivatives from agarwood and their inhibitory effects on tumor cells Open
Two new chromone derivatives, 7-hydroxy-2-[2-(3'-methoxy-4'-hydroxyphenyl)-ethyl]chromone (1), and 6,7-dimethoxy-2-[2-(3'-hydroxyphenyl)-ethyl]chromone (2) were isolated from the EtOH extract of agarwood of Aquilaria sinen…
View article: Agarwood Essential Oil Ameliorates Restrain Stress-Induced Anxiety and Depression by Inhibiting HPA Axis Hyperactivity
Agarwood Essential Oil Ameliorates Restrain Stress-Induced Anxiety and Depression by Inhibiting HPA Axis Hyperactivity Open
In our previous investigation, we found that agarwood essential oil (AEO) has a sedative-hypnotic effect. Sedative-hypnotic drugs usually have an anxiolytic effect, where concomitant anxiety and depression are a common comorbidity. Therefo…
View article: Chemical Constituents and Pharmacological Activity of Agarwood and Aquilaria Plants
Chemical Constituents and Pharmacological Activity of Agarwood and Aquilaria Plants Open
Agarwood, a highly precious non-timber fragrant wood of Aquilaria spp. (Thymelaeaceae), has been widely used in traditional medicine, religious rites, and cultural activities. Due to the inflated demanding and depleted natural resources, t…
View article: Clerodane Diterpenes from the Roots of <i>Polyalthia laui</i>
Clerodane Diterpenes from the Roots of <i>Polyalthia laui</i> Open
a,b 余章昕 a ( a 海南师范大学化学与化工学院 热带药用植物化学教育部重点实验室 海口 571158) ( b 海南省药食同源植物资源重点实验室 海南科技职业学院化学与材料工程学院 海口 571126) 摘要 对海南暗罗根化学成分进行系统研究, 分离得到 5 个克罗烷型二萜类化合物.根据它们的 NMR 和 HRMS 数据, 鉴定它们的结构分别为: (4→2)重排-2,13-二甲酰基-克罗烷-2,12E-二双键-15-甲酯(1)、克罗烷-3,12E-二双键-15,16…
View article: Secondary Metabolites of a<i>Bruguiera sexangula var</i>.<i>Rhynchopetala</i>-Derived Fungus<i>Phomopsis longicolla</i>HL-2232
Secondary Metabolites of a<i>Bruguiera sexangula var</i>.<i>Rhynchopetala</i>-Derived Fungus<i>Phomopsis longicolla</i>HL-2232 Open
黄国雷 余章昕 宋小平 陈光英 (海南师范大学化学与化工学院 海南师范大学热带药用植物化学教育部重点实验室 海口 571158) 摘要 通过活性追踪的方法, 从一株来源于药用红树尖瓣海莲的内生真菌 Phomopsis longicolla HL