Zhanhong Du
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View article: Collagen-based biomaterials in neural injury repair: current advances and future perspectives
Collagen-based biomaterials in neural injury repair: current advances and future perspectives Open
View article: Functional Nanomaterials for Advanced Bioelectrode Interfaces: Recent Advances in Disease Detection and Metabolic Monitoring
Functional Nanomaterials for Advanced Bioelectrode Interfaces: Recent Advances in Disease Detection and Metabolic Monitoring Open
As critical interfaces bridging biological systems and electronic devices, the performance of bioelectrodes directly determines the sensitivity, selectivity, and reliability of biosensors. Recent advancements in functional nanomaterials (e…
View article: Recent Advances in Flexible Sensors for Neural Interfaces: Multimodal Sensing, Signal Integration, and Closed-Loop Feedback
Recent Advances in Flexible Sensors for Neural Interfaces: Multimodal Sensing, Signal Integration, and Closed-Loop Feedback Open
The rapid advancement of flexible sensor technology has profoundly transformed neural interface research, enabling multimodal information acquisition, real-time neurochemical and electrophysiological signal monitoring, and adaptive closed-…
View article: Delayed muscle fatigue during electrical stimulation of the proximal nerve using asymmetric random high-frequency carrier pulse cluster
Delayed muscle fatigue during electrical stimulation of the proximal nerve using asymmetric random high-frequency carrier pulse cluster Open
View article: Advances in the application of temporal interference stimulation: a scoping review
Advances in the application of temporal interference stimulation: a scoping review Open
Introduction Neuromodulation is an emerging technology that combines biomedical engineering and neuroscience to modulate the nervous system using implantable or non-implantable devices, which have proven effective in treating neurodegenera…
View article: High‐Performance MXene/PEDOT‐PSS Microscale Fiber Electrodes for Neural Recording and Stimulation (Adv. Funct. Mater. 20/2025)
High‐Performance MXene/PEDOT‐PSS Microscale Fiber Electrodes for Neural Recording and Stimulation (Adv. Funct. Mater. 20/2025) Open
View article: KiT: A Deep Learning Diagnostic Model of EEG Signals from Disorders of Consciousness Patients Based on Kolmogorov Arnold Network - Vision Transformer
KiT: A Deep Learning Diagnostic Model of EEG Signals from Disorders of Consciousness Patients Based on Kolmogorov Arnold Network - Vision Transformer Open
View article: Long‐Term Neural Recording Performance of PEDOT/CNT/Dexamethasone‐Coated Electrode Array Implanted in Visual Cortex of Rats
Long‐Term Neural Recording Performance of PEDOT/CNT/Dexamethasone‐Coated Electrode Array Implanted in Visual Cortex of Rats Open
Implantable neural electrode arrays can be inserted in the brain to provide single‐cell electrophysiology recording for neuroscience research and brain–machine interface applications. However, maintaining signal quality over time is compli…
View article: Advanced neuroprosthetic electrode design optimized by electromagnetic finite element simulation: innovations and applications
Advanced neuroprosthetic electrode design optimized by electromagnetic finite element simulation: innovations and applications Open
Based on electrophysiological activity, neuroprostheses can effectively monitor and control neural activity. Currently, electrophysiological neuroprostheses are widely utilized in treating neurological disorders, particularly in restoring …
View article: Stacked MXene/PEDOT-PSS Electrode Fiber for High-Performance Recording and Stimulation
Stacked MXene/PEDOT-PSS Electrode Fiber for High-Performance Recording and Stimulation Open
The development of microelectrodes with high electrical performance is imperative, particularly for invasive interfaces such as deep brain stimulation (DBS) electrodes. MXene, a new family of 2D early transition metal carbides or nitrides,…
View article: Applications of 2D Nanomaterials in Neural Interface
Applications of 2D Nanomaterials in Neural Interface Open
Neural interfaces are crucial conduits between neural tissues and external devices, enabling the recording and modulation of neural activity. However, with increasing demand, simple neural interfaces are no longer adequate to meet the requ…
View article: Neural repair and regeneration interfaces: a comprehensive review
Neural repair and regeneration interfaces: a comprehensive review Open
Neural interfaces play a pivotal role in neuromodulation, as they enable precise intervention into aberrant neural activity and facilitate recovery from neural injuries and resultant functional impairments by modulating local immune respon…
View article: Doping-induced assembly interface for noninvasive in vivo local and systemic immunomodulation
Doping-induced assembly interface for noninvasive in vivo local and systemic immunomodulation Open
Peripheral neural interfaces, potent in modulating local and systemic immune responses for disease treatment, face significant challenges due to the peripheral nerves’ broad distribution in tissues like the fascia, periosteum, and skin. Th…
View article: Sensing and Stimulation Applications of Carbon Nanomaterials in Implantable Brain-Computer Interface
Sensing and Stimulation Applications of Carbon Nanomaterials in Implantable Brain-Computer Interface Open
Implantable brain–computer interfaces (BCIs) are crucial tools for translating basic neuroscience concepts into clinical disease diagnosis and therapy. Among the various components of the technological chain that increases the sensing and …
View article: Multi-Functionalized Self-Bonding MXene for Minimal-invasive Jet-injected Neural Interface and Tissue Healing
Multi-Functionalized Self-Bonding MXene for Minimal-invasive Jet-injected Neural Interface and Tissue Healing Open
Implantable central and peripheral neural interfaces have great potential in treating various nerve injuries and diseases. Still, limitations of surgery trauma, handling inconvenience, and biocompatibility issues of available materials and…
View article: Residual voltage as an ad-hoc indicator of electrode damage in biphasic electrical stimulation
Residual voltage as an ad-hoc indicator of electrode damage in biphasic electrical stimulation Open
Objective. We derive and demonstrate how residual voltage (RV) from a biphasic electrical stimulation pulse can be used to recognize degradation at the electrode-tissue interface. Approach. Using a first order model of the electrode-tissue…
View article: Impaired Parahippocampal Gyrus–Orbitofrontal Cortex Circuit Associated with Visuospatial Memory Deficit as a Potential Biomarker and Interventional Approach for Alzheimer Disease
Impaired Parahippocampal Gyrus–Orbitofrontal Cortex Circuit Associated with Visuospatial Memory Deficit as a Potential Biomarker and Interventional Approach for Alzheimer Disease Open
View article: The Glutamatergic Postrhinal Cortex–Ventrolateral Orbitofrontal Cortex Pathway Regulates Spatial Memory Retrieval
The Glutamatergic Postrhinal Cortex–Ventrolateral Orbitofrontal Cortex Pathway Regulates Spatial Memory Retrieval Open
View article: Ultrasoft microwire neural electrodes improve chronic tissue integration
Ultrasoft microwire neural electrodes improve chronic tissue integration Open
View article: Aptamer-functionalized neural recording electrodes for the direct measurement of cocaine in vivo
Aptamer-functionalized neural recording electrodes for the direct measurement of cocaine in vivo Open
First everin vivosensor for directly measuring cocaine concentration in the brainviaelectrochemical detection at DNA aptamer functionalized single shank, silicon-based neural recording probes.
View article: Correction: Aptamer-functionalized neural recording electrodes for the direct measurement of cocaine in vivo
Correction: Aptamer-functionalized neural recording electrodes for the direct measurement of cocaine in vivo Open
Correction for ‘Aptamer-functionalized neural recording electrodes for the direct measurement of cocaine in vivo’ by I. Mitch Taylor et al., J. Mater. Chem. B, 2017, 5, 2445–2458.
View article: In Vivo Electrochemical Analysis of a PEDOT/MWCNT Neural Electrode Coating
In Vivo Electrochemical Analysis of a PEDOT/MWCNT Neural Electrode Coating Open
Neural electrodes hold tremendous potential for improving understanding of brain function and restoring lost neurological functions. Multi-walled carbon nanotube (MWCNT) and dexamethasone (Dex)-doped poly(3,4-ethylenedioxythiophene) (PEDOT…
View article: Chronic <i>In Vivo</i> Evaluation of PEDOT/CNT for Stable Neural Recordings
Chronic <i>In Vivo</i> Evaluation of PEDOT/CNT for Stable Neural Recordings Open
This project uses leading-edge biomaterials to develop chronic neural probes that are small (subcellular) with excellent electrical properties for stable long-term recordings. High-density ultrasmall electrodes combined with advanced elect…
View article: Modulation of in Vivo Neural Network Activity with Electrochemically Controlled Delivery of Neuroactive Molecules
Modulation of in Vivo Neural Network Activity with Electrochemically Controlled Delivery of Neuroactive Molecules Open
Neural interface technologies with implantable microelectrode arrays hold great promise for treating neural injuries or disorders. On neural electrode surfaces, conducting polymers can be electropolymerization with negatively charged molec…
View article: Poly(3,4-ethylenedioxythiophene)-ionic liquid coating improves neural recording and stimulation functionality of MEAs
Poly(3,4-ethylenedioxythiophene)-ionic liquid coating improves neural recording and stimulation functionality of MEAs Open
A novel PEDOT-ionic liquid polymer coating was synthesized for improving the performance of MEAs implanted in the brain.