Zhuoying Huang
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View article: Genomic surveillance reveals global spread of macrolide-resistant <i>Bordetella pertussis</i> linked to vaccine changes
Genomic surveillance reveals global spread of macrolide-resistant <i>Bordetella pertussis</i> linked to vaccine changes Open
The resurgence of whooping cough in regions utilizing acellular pertussis vaccines underscores emerging public health challenges. Here, we characterized 178 Bordetella pertussis isolates collected from patients across all age groups in Sha…
View article: Assessing barriers and facilitators of attitudes toward seasonal influenza vaccination among pregnant women using the Health Belief Model
Assessing barriers and facilitators of attitudes toward seasonal influenza vaccination among pregnant women using the Health Belief Model Open
Pregnant women are at elevated risk of severe influenza-related complications and maternal influenza vaccination protects mothers and infants. Nevertheless, the global maternal influenza vaccination rates remain critically low. This cross-…
View article: Distribution of perivascular spaces distribution and relate to the clinical features of SCA3
Distribution of perivascular spaces distribution and relate to the clinical features of SCA3 Open
Background Spinocerebellar ataxia type 3 (SCA3) is a rare neurodegenerative condition. Prior research has established perivascular spaces (PVS) expansion has been implicated in the pathogenesis and prognosis of various neurodegenerative di…
View article: Influenza Vaccination and Short‐Term Risk of Stroke Among Elderly Patients With Chronic Comorbidities in a Population‐Based Cohort Study
Influenza Vaccination and Short‐Term Risk of Stroke Among Elderly Patients With Chronic Comorbidities in a Population‐Based Cohort Study Open
The protective effect of influenza vaccination on stroke risk has been inconclusive. In this study, we aimed to investigate the impact of influenza vaccination on the 1‐year risk of stroke in individuals aged 60 years and older with COPD a…
View article: Impact of the COVID-19 pandemic on the timeliness of pertussis-containing vaccination: A cohort study in Shanghai, China
Impact of the COVID-19 pandemic on the timeliness of pertussis-containing vaccination: A cohort study in Shanghai, China Open
The COVID-19 epidemic has significantly disrupted routine childhood immunization programs. This study assesses the impact of different COVID-19 prevalence phases on immunization coverage and timeliness in Shanghai, China. We employed a ret…
View article: Immunogenicity and safety study of 23-valent pneumococcal polysaccharide vaccine revaccination among elderly individuals aged 60–70 years in Shanghai, China
Immunogenicity and safety study of 23-valent pneumococcal polysaccharide vaccine revaccination among elderly individuals aged 60–70 years in Shanghai, China Open
Background To understand the immunogenicity and safety of the 23-valent pneumococcal polysaccharide vaccine in elderly individuals aged 60–70 years in Shanghai after revaccination. Methods A total of 330 elderly people aged 60–70 years wer…
View article: HPV vaccination coverage, hesitancy, and barriers: Insights from a serial cross-sectional study in Shanghai, China (2019–2024)
HPV vaccination coverage, hesitancy, and barriers: Insights from a serial cross-sectional study in Shanghai, China (2019–2024) Open
Cervical cancer is the fourth most common cancer among women globally and a significant public health challenge in China, which accounts for nearly 18% of global cervical cancer cases. The HPV vaccine is a proven intervention for preventin…
View article: Longitudinal association between parents’ reported vaccination program preferences and children’s actual immunization patterns in Shanghai, China
Longitudinal association between parents’ reported vaccination program preferences and children’s actual immunization patterns in Shanghai, China Open
Background As China expands its national immunization program, it is essential to understand parents’ beliefs about pediatric vaccination programs and the translation into actual vaccination decision-making for their children. This study a…
View article: Antibody Persistence of Human Diploid Cell Rabies Vaccine Administrated Using the Four-Versus Five-Dose Essen Intramuscular Regimen in Post-Exposure Prophylaxis: A Prospective Cohort Study Among the Chinese Population
Antibody Persistence of Human Diploid Cell Rabies Vaccine Administrated Using the Four-Versus Five-Dose Essen Intramuscular Regimen in Post-Exposure Prophylaxis: A Prospective Cohort Study Among the Chinese Population Open
Objective: Evidence on long-term antibody persistence for the rabies vaccine administered using the four-dose Essen regimen is lacking. This study compared antibody persistence for the human diploid cell rabies vaccine (HDCV) administered …
View article: Rotavirus vaccine effectiveness and coverage among children younger than 5 years old in Shanghai, China: A test-negative case control study
Rotavirus vaccine effectiveness and coverage among children younger than 5 years old in Shanghai, China: A test-negative case control study Open
RotaTeq demonstrates a robust protective effectiveness, while LLR provides a certain level of protection against mild to moderate rotavirus diarrhea in children in Shanghai. For privately purchased (non-NIP) vaccines, we estimate that the …
View article: Ten proposed measures to improve vaccination: Health care providers’ perspectives on promoting the vaccination intake of children with special healthcare needs in China
Ten proposed measures to improve vaccination: Health care providers’ perspectives on promoting the vaccination intake of children with special healthcare needs in China Open
Introduction Children with special healthcare needs (CSHCN) often experience vaccination delays or missed vaccines in China. The coverage rate of the age-appropriate National Immunisation Programme vaccine was suboptimal. This study aimed …
View article: Safety of an inactivated enterovirus 71 vaccine administered concurrently with other vaccines among infants aged 6–11 months: An observational study using active surveillance
Safety of an inactivated enterovirus 71 vaccine administered concurrently with other vaccines among infants aged 6–11 months: An observational study using active surveillance Open
Vaccine co-administration can efficiently increase vaccination uptake and timely immunization. This study aimed to evaluate the safety of the enterovirus 71 (EV71) vaccine administered alone or concurrently with other vaccines in infants 6…
View article: Evaluation of pre-school pertussis booster vaccination in Shanghai, China: A cost-effectiveness analysis
Evaluation of pre-school pertussis booster vaccination in Shanghai, China: A cost-effectiveness analysis Open
Implementing acellular pertussis booster immunization for 6-year-old pre-school children in Shanghai emerges as a cost-saving immunization strategy, with both cost savings and utility gains.
View article: Complex interplay of science reasoning and vaccine hesitancy among parents in Shanghai, China
Complex interplay of science reasoning and vaccine hesitancy among parents in Shanghai, China Open
The psychosocial underpinnings of vaccine hesitancy are complex. Research is needed to pinpoint the exact reasons why people hesitate to vaccinate themselves or their children against vaccine-preventable diseases. One possible reason are c…
View article: Persistence of antibody to 23-valent pneumococcal polysaccharide vaccine: a 5-year prospective follow-up cohort study
Persistence of antibody to 23-valent pneumococcal polysaccharide vaccine: a 5-year prospective follow-up cohort study Open
The pneumococcal antibodies in elderly after PPV23 vaccination could sustain high levels over long-term follow-up, which suggested that the interval of revaccination with PPV23 in elderly should be at least 5 years after the first vaccinat…
View article: Epidemiological Characteristics of Human Rabies in Urban and Suburban Districts in Shanghai, 2006–2021
Epidemiological Characteristics of Human Rabies in Urban and Suburban Districts in Shanghai, 2006–2021 Open
Objective: Rabies is a vaccine-preventable, viral zoonotic disease caused by a lyssavirus. This study was aimed at analyzing the epidemiological characteristics of human rabies in Shanghai to provide valuable information to support accurat…
View article: Serological surveillance on potential Plasmodium vivax exposure risk in a post-elimination setting
Serological surveillance on potential Plasmodium vivax exposure risk in a post-elimination setting Open
China was declared malaria free in June of 2021. In the post-elimination setting, vigilant surveillance is essential to sustain malaria free status. Serological surveillance has been recognized as an efficient tool for assessing the immuni…
View article: Effectiveness of inactivated and Ad5-nCoV COVID-19 vaccines against SARS-CoV-2 Omicron BA. 2 variant infection, severe illness, and death
Effectiveness of inactivated and Ad5-nCoV COVID-19 vaccines against SARS-CoV-2 Omicron BA. 2 variant infection, severe illness, and death Open
Background Limited data are available on effectiveness of inactivated and Ad5-nCoV COVID-19 vaccines in real-world use - especially against Omicron variants in SARS-CoV-2 infection-naïve population. During an outbreak in Shanghai’s SARS-Co…
View article: Characteristics and Genomic Diversity of Measles Virus From Measles Cases With Known Vaccination Status in Shanghai, China
Characteristics and Genomic Diversity of Measles Virus From Measles Cases With Known Vaccination Status in Shanghai, China Open
Although the highly effective measles vaccine has dramatically reduced the incidence of measles, measles, and outbreaks continue to occur in individuals who received the measles vaccine because of immunization failure. In this study, patie…
View article: Measuring parents’ acceptance of non-national immunization program vaccines for children and its influencing factors during the COVID-19 pandemic in Shanghai, China
Measuring parents’ acceptance of non-national immunization program vaccines for children and its influencing factors during the COVID-19 pandemic in Shanghai, China Open
This study aimed to understand the willingness of and affecting factors of non-national immunization program (non-NIP) vaccines among children's parents during the COVID-19 era in Shanghai, China. A cross-sectional survey was conducted wit…
View article: Evaluation of influenza vaccination coverage in Shanghai city during the 2016/17 to 2020/21 influenza seasons
Evaluation of influenza vaccination coverage in Shanghai city during the 2016/17 to 2020/21 influenza seasons Open
Influenza is a common infectious disease resulting in substantial morbidity and mortality globally. The most effective strategy for preventing influenza is annual vaccination; however, the coverage rate of the influenza vaccine in Shanghai…
View article: Willingness to Receive a COVID-19 Vaccine and Associated Factors among Older Adults: A Cross-Sectional Survey in Shanghai, China
Willingness to Receive a COVID-19 Vaccine and Associated Factors among Older Adults: A Cross-Sectional Survey in Shanghai, China Open
Background: Older individuals have a high risk of morbidity and mortality due to COVID-19, and one of the most effective ways to prevent COVID-19 is vaccination. Little is known about older people’s willingness to receive a COVID-19 vaccin…
View article: Vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in Shanghai, China
Vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in Shanghai, China Open
Given increased global concern about vaccine hesitancy, this study estimates coverage of mandatory vs non-mandatory vaccines in children, and assesses whether vaccine hesitancy among young parents relates to their child's eventual vaccinat…