Rui Zhao YOU? Author Swipe

Last 10y

U1 snRNP and RNA polymerase II interaction is predominantly mediated by Prp40 rather than U1-70K in yeast Open

Xueni Li, Jiaqin Li, Pankaj Srivastava, Shasha Shi, Aaron Issaian , et al. · 2025

Transcription and splicing are coupled both temporally and physically. A previous cryo-EM structure of the human U1 snRNP and RNA polymerase pol II complex has shown that U1 snRNP uses predominantly the RRM domain of U1-70K to directly int…

The U1 snRNP protein U1C and Helix H of U1 snRNA are critical for small molecule splicing modulator function Open

Zhiling Kuang, Xueni Li, Zhichao Tang, Brian Kosmyna, Shasha Shi , et al. · 2025

Risdiplam and branaplam represent two classes of small-molecule splicing modulators that promote U1 snRNP recognition of weak non-canonical GA/GU-containing 5’ splice sites (ss). We demonstrated that branaplam enhanced recognition of these…

Cryo-EM structures reveal the PP2A–B55α and Eya3 interaction that can be disrupted by a peptide inhibitor Open

Shasha Shi, Xueni Li, Christopher P Alderman, Lars Wick, Wei Huang , et al. · 2025

We have previously shown that Eya3 recruits PP2A-B55α to dephosphorylate pT58 on Myc, increasing Myc stability and enhancing primary tumor growth of triple-negative breast cancer (TNBC). However, the molecular details of how Eya3 recruits …

Unraveling the mechanism of how small molecule modulates 5' splice site recognition Open

Shasha Shi, Xueni Li, Zhiling Kuang, Bryan M. Dunyak, Frédéric H. Vaillancourt , et al. · 2025

Pre-mRNA splicing, facilitated by the spliceosome, is crucial for eukaryotic gene regulation. U1snRNP, a component of the spliceosome, plays a crucial role in recognizing the 5' splice site (ss) during splicing initiation through the base …

Understanding the Structure and Function of Alternative Splicing Factor PRPF39 Open

Carole Wright, Shasha Shi, Francesca De Bortoli, Jerzy Kotz, Xueni Li , et al. · 2025

Gene expression in eukaryotes requires multiple processing steps between RNA and protein. This includes the splicing of introns and exons, a critical process. Mis-splicing and improper splicing products can result in disease states, thus n…

Data for EMSL Project 48666 from July 2020 Open

Karin Rodland, Anil Shukla, Richard Smith, David Camp, Rui Zhao , et al. · 2024

Mapping microhabitats of lignocellulose decomposition by a microbial consortium Open

Marija Veličković, Ruonan Wu, Yuqian Gao, Margaret W. Thairu, Dušan Veličković , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

Data for EMSL Project 49531 from January 2024 Open

Keqi Tang, Richard Smith, Ljiljana Paša‐Tolić, Rui Zhao, Desmond Smith , et al. · 2024

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