Zhao Su
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View article: The Applications of PD1 Monoclonal Antibody in Non-small Cell Lung Cancer
The Applications of PD1 Monoclonal Antibody in Non-small Cell Lung Cancer Open
Lung cancer is currently the most deadly type of cancer, with non-small cell lung cancer dominating, thus making it the primary focus of clinical research and treatment. Despite advances in modern medicine, traditional treatment methods st…
View article: Research progress of in vivo measurement methods of myopia sclera biomechanics
Research progress of in vivo measurement methods of myopia sclera biomechanics Open
The review shows that the most urgent problem is to further prove and verify that the biomechanical properties of the sclera can be measured with sufficient sensitivity and accuracy in vivo. Its safety and feasibility in clinical applicati…
View article: Rethinking MYC inhibition: a multi-dimensional approach to overcome cancer’s master regulator
Rethinking MYC inhibition: a multi-dimensional approach to overcome cancer’s master regulator Open
MYC, a master regulator in oncogenesis, has long been deemed “undruggable” due to its intrinsically disordered structure. However, recent advances are overturning this view, with direct inhibitors like Omomyc (OMO-103) and PROTAC-based deg…
View article: Developmentally dependent reprogramming of the Arabidopsis floral transcriptome under sufficient and limited water availability
Developmentally dependent reprogramming of the Arabidopsis floral transcriptome under sufficient and limited water availability Open
View article: Supplementary Figure 6 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure 6 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 350KB
View article: Supplementary Figure 1 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure 1 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 1333KB
View article: Data from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Data from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
Aggressive tumor growth, diffuse tissue invasion, and neurodegeneration are hallmarks of malignant glioma. Although glutamate excitotoxicity is considered to play a key role in glioma-induced neurodegeneration, the mechanism(s) controlling…
View article: Supplementary Figure 7 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure 7 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 442KB
View article: Supplementary Figure 3 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure 3 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 129KB
View article: Supplementary Figure Legend from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure Legend from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 87KB
View article: Supplementary Figure 3 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure 3 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 129KB
View article: Supplementary Figure 4 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure 4 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 164KB
View article: Supplementary Figure 5 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure 5 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 481KB
View article: Supplementary Figure 5 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure 5 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 481KB
View article: Supplementary Figure 6 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure 6 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 350KB
View article: Supplementary Figure 2 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure 2 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 2192KB
View article: Supplementary Figure 7 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure 7 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 442KB
View article: Data from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Data from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
Aggressive tumor growth, diffuse tissue invasion, and neurodegeneration are hallmarks of malignant glioma. Although glutamate excitotoxicity is considered to play a key role in glioma-induced neurodegeneration, the mechanism(s) controlling…
View article: Supplementary Figure 2 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure 2 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 2192KB
View article: Supplementary Figure 1 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure 1 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 1333KB
View article: Supplementary Figure 4 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure 4 from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 164KB
View article: Supplementary Figure Legend from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
Supplementary Figure Legend from Oncogene <i>AEG-1</i> Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity Open
PDF file - 87KB
View article: Molecular genetic analyses of abiotic stress responses during plant reproductive development
Molecular genetic analyses of abiotic stress responses during plant reproductive development Open
Plant responses to abiotic stresses during vegetative growth have been extensively studied for many years. Daily environmental fluctuations can have dramatic effects on plant vegetative growth at multiple levels, resulting in molecular, ce…
View article: Tissue-specific changes in the RNA structurome mediate salinity response in <i>Arabidopsis</i>
Tissue-specific changes in the RNA structurome mediate salinity response in <i>Arabidopsis</i> Open
Little is known concerning the effects of abiotic factors on in vivo RNA structures. We applied Structure-seq to assess the in vivo mRNA structuromes of Arabidopsis thaliana under salinity stress, which negatively impacts agriculture. Stru…
View article: Tissue-specific changes in the RNA structurome mediate salinity response in<i>Arabidopsis</i>
Tissue-specific changes in the RNA structurome mediate salinity response in<i>Arabidopsis</i> Open
RNA structures are influenced by their physico-chemical environment. Few studies have assessed genome-wide impacts of abiotic stresses on in vivo RNA structure, however, and none have investigated tissue-specificity. We applied our Structu…
View article: Genome-wide RNA structurome reprogramming by acute heat shock globally regulates mRNA abundance
Genome-wide RNA structurome reprogramming by acute heat shock globally regulates mRNA abundance Open
The heat shock response is crucial for organism survival in natural environments. RNA structure is known to influence numerous processes related to gene expression, but there have been few studies on the global RNA structurome as it prevai…
View article: Illuminating the role of the Gα heterotrimeric G protein subunit, RGA1, in regulating photoprotection and photoavoidance in rice
Illuminating the role of the Gα heterotrimeric G protein subunit, RGA1, in regulating photoprotection and photoavoidance in rice Open
We studied physiological mechanisms of photoavoidance and photoprotection of a dwarf rice mutant with erect leaves, d1 , in which the RGA1 gene, which encodes the Gα subunit of the heterotrimeric G protein, is non‐functional. Leaves of d1 …
View article: Structure-seq2: sensitive and accurate genome-wide profiling of RNA structure in vivo
Structure-seq2: sensitive and accurate genome-wide profiling of RNA structure in vivo Open
RNA serves many functions in biology such as splicing, temperature sensing, and innate immunity. These functions are often determined by the structure of RNA. There is thus a pressing need to understand RNA structure and how it changes dur…