Zhimou Guo
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View article: Identification of a Novel NPC1L1 Inhibitor from Danshen and Its Role in Nonalcoholic Fatty Liver Disease
Identification of a Novel NPC1L1 Inhibitor from Danshen and Its Role in Nonalcoholic Fatty Liver Disease Open
Danshen, a well-known traditional Chinese medicine (TCM), has gained increasing attention for its protective effects on nonalcoholic fatty liver disease (NAFLD). However, the molecular mechanisms underlying these effects remain to be eluci…
View article: Soft, Stretchable, High-Sensitivity, Multi-Walled Carbon Nanotube-Based Strain Sensor for Joint Healthcare
Soft, Stretchable, High-Sensitivity, Multi-Walled Carbon Nanotube-Based Strain Sensor for Joint Healthcare Open
Exoskeletons play a crucial role in joint healthcare by providing targeted support and rehabilitation for individuals with musculoskeletal diseases. As an assistive device, the accurate monitoring of the user’s joint signals and exoskeleto…
View article: <span style="mso-fareast-font-family: DengXian;">Cryptotanshinone Alleviates Nonalcoholic Fatty Liver Disease by Inhibiting NPC1L1<span style="mso-bookmark: OLE_LINK36;">-Mediated <span style="mso-bookmark: OLE_LINK36;"><span style="mso-bookmark: OLE_LINK182;">Intestinal Cholesterol Absorption
<span>Cryptotanshinone Alleviates Nonalcoholic Fatty Liver Disease by Inhibiting NPC1L1<span>-Mediated <span><span>Intestinal Cholesterol Absorption Open
Danshen, a well-known traditional Chinese medicine (TCM), has gained increasing attention due to the protective effects on nonalcoholic fatty liver disease (NAFLD). However, the molecular basis and working mechanism remain to be elucidated…
View article: Experimental Study on Fracture Propagation in Carbonate Rocks by Acid Fracturing Using the Image-Based 3D Object Reconstruction Technique
Experimental Study on Fracture Propagation in Carbonate Rocks by Acid Fracturing Using the Image-Based 3D Object Reconstruction Technique Open
Acid fracturing is an effective method of reservoir stimulation and has been widely used for carbonate reservoir development. However, knowledge on the propagation characteristics of acid-etched fracture is still poor due to the complexiti…
View article: Isolation of Human Milk Difucosyl Nona- and Decasaccharides by Ultrahigh-Temperature Preparative PGC-HPLC and Identification of Novel Difucosylated Heptaose and Octaose Backbones by Negative-Ion ESI-MS<sup>n</sup>
Isolation of Human Milk Difucosyl Nona- and Decasaccharides by Ultrahigh-Temperature Preparative PGC-HPLC and Identification of Novel Difucosylated Heptaose and Octaose Backbones by Negative-Ion ESI-MS<sup>n</sup> Open
Despite their many important physiological functions, past work on the diverse sequences of human milk oligosaccharides (HMOs) has been focused mainly on the highly abundant HMOs with a relatively low degree of polymerization (DP) due to t…
View article: [Development progress of stationary phase for supercritical fluid chromatography and related application in natural products].
[Development progress of stationary phase for supercritical fluid chromatography and related application in natural products]. Open
Supercritical fluid chromatography (SFC) is an environment-friendly and efficient column chromatography technology that was developed to expand the application range of high performance liquid chromatography (HPLC) using a supercritical fl…
View article: Development and Characterization of Fluorescent Probes for the G Protein-Coupled Receptor 35
Development and Characterization of Fluorescent Probes for the G Protein-Coupled Receptor 35 Open
The orphan G protein-coupled receptor 35 (GPR35) is a potential target for the treatment of pain, inflammation, and metabolic diseases. Although many GPR35 agonists have been discovered, research on functional GPR35 ligands, such as fluore…
View article: Simultaneous Determination and Distribution Analysis of Eleven Arsenic Species in Vegetables
Simultaneous Determination and Distribution Analysis of Eleven Arsenic Species in Vegetables Open
View article: Decipher Molecular Composition of Surface Deposited Dust Via Fourier Transform Ion Cyclotron Resonance Mass Spectrometry and Database Matching to Assess Potential Chemical Risks of Historical Heritage
Decipher Molecular Composition of Surface Deposited Dust Via Fourier Transform Ion Cyclotron Resonance Mass Spectrometry and Database Matching to Assess Potential Chemical Risks of Historical Heritage Open
View article: An Integrated Study on the Fading Mechanism of Malachite Green Industrial Dye for the Marquisette Curtain in the Studio of Cleansing Fragrance, the Palace Museum (Beijing)
An Integrated Study on the Fading Mechanism of Malachite Green Industrial Dye for the Marquisette Curtain in the Studio of Cleansing Fragrance, the Palace Museum (Beijing) Open
Historical marquisette curtains were composed of lightweight fabrics, woven in an open-mesh and leno-type weave, usually made of silk, and found in Qing imperial buildings. As panel curtains, they were exposed to light, and so underwent fa…
View article: Characterization of rat and mouse acidic milk oligosaccharides based on hydrophilic interaction chromatography coupled with electrospray tandem mass spectrometry
Characterization of rat and mouse acidic milk oligosaccharides based on hydrophilic interaction chromatography coupled with electrospray tandem mass spectrometry Open
Oligosaccharides are one of the most important components in mammalian milk. Milk oligosaccharides can promote colonization of gut microbiota and protect newborns from infections. The diversity and structures of MOs differ among mammalian …
View article: Fucosylated Human Milk Oligosaccharides and N-Glycans in the Milk of Chinese Mothers Regulate the Gut Microbiome of Their Breast-Fed Infants during Different Lactation Stages
Fucosylated Human Milk Oligosaccharides and N-Glycans in the Milk of Chinese Mothers Regulate the Gut Microbiome of Their Breast-Fed Infants during Different Lactation Stages Open
Human milk glycans provide a broad range of carbon sources for gut microbes in infants. Levels of protein glycosylation in human milk vary during lactation and may also be affected by the stages of gestation and lactation and by the secret…
View article: Profiling of Sialylated Oligosaccharides in Mammalian Milk Using Online Solid Phase Extraction-Hydrophilic Interaction Chromatography Coupled with Negative-Ion Electrospray Mass Spectrometry
Profiling of Sialylated Oligosaccharides in Mammalian Milk Using Online Solid Phase Extraction-Hydrophilic Interaction Chromatography Coupled with Negative-Ion Electrospray Mass Spectrometry Open
Sialylated oligosaccharides are important components in mammalian milk. They play a key role in the health and growth of infants by helping to shape up infant's gastrointestinal microbiota and defense against infection by various pathogeni…
View article: Mesoporous silica–carbon composites fabricated by a universal strategy of hydrothermal carbonization: controllable synthesis and applications
Mesoporous silica–carbon composites fabricated by a universal strategy of hydrothermal carbonization: controllable synthesis and applications Open
A carbon layer with controlled thickness can be coated on the surface of mesoporous silica through the hydrothermal carbonization strategy.