Zhaomin Deng
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View article: Targeting TFAP2β condensation suppresses the development of esophageal squamous cell carcinoma
Targeting TFAP2β condensation suppresses the development of esophageal squamous cell carcinoma Open
Exploring targeted therapies for esophageal squamous cell carcinoma (ESCC) remains challenging. Although investigating the roles and therapeutic applications of liquid-liquid phase separation (LLPS) is increasingly of interest, its relatio…
View article: Identification and functional analysis of five hub lncRNAs associated with oncogenesis of Hepatocellular Carcinoma
Identification and functional analysis of five hub lncRNAs associated with oncogenesis of Hepatocellular Carcinoma Open
Liver cancer stands as one of the most pervasive and aggressive malignant neoplasms on a global scale, with hepatocellular carcinoma (HCC) accounting for over 90% of primary liver cancer cases. It has been documented that long non-coding R…
View article: [Network Pharmacology Study of Compound Ligustrazine in Gastric Cancer Therapy].
[Network Pharmacology Study of Compound Ligustrazine in Gastric Cancer Therapy]. Open
In this study, by using multiple analysis methods in an integrated way, we found that ligustrazine may have therapeutic effects on gastric cancer by regulating the potential targets of ELANE and MPO, as well as the relevant signaling pathw…
View article: Acceptance and Factors Associated With Participation in Functional Cure–Related Trials Among People Living With HIV: A Cross-sectional Study in Southern China
Acceptance and Factors Associated With Participation in Functional Cure–Related Trials Among People Living With HIV: A Cross-sectional Study in Southern China Open
HIV remains a global health challenge, and research efforts directed towards a functional cure require people living with HIV (PLHIV) involvement in clinical trials. Our study assessed willingness to participate in HIV functional cure–rela…
View article: Acceptance of COVID‐19 booster vaccination based on the protection motivation theory: A cross‐sectional study in China
Acceptance of COVID‐19 booster vaccination based on the protection motivation theory: A cross‐sectional study in China Open
The promotion of the booster shots against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection is an open issue to be discussed. Little is known about the public intention and the influencing factors regarding the booste…
View article: Comparison of the Immunogenicity of HIV-1 CRF07_BC Gag Antigen With or Without a Seven Amino Acid Deletion in p6 Region
Comparison of the Immunogenicity of HIV-1 CRF07_BC Gag Antigen With or Without a Seven Amino Acid Deletion in p6 Region Open
HIV-1 CRF07_BC-p6Δ7, a strain with a seven amino acid deletion in the p6 region of the Gag protein, is becoming the dominant strain of HIV transmission among men who have sex with men (MSM) in China. Previous studies demonstrated that HIV-…
View article: Factors associated with COVID-19 vaccination acceptance among industrial workers in the post-vaccination era: a large-scale cross-sectional survey in China
Factors associated with COVID-19 vaccination acceptance among industrial workers in the post-vaccination era: a large-scale cross-sectional survey in China Open
This study calls for more attention and health-related education among industrial workers to improve their acceptance of COVID-19 vaccination.
View article: Changes in Mental Health and Preventive Behaviors before and after COVID-19 Vaccination: A Propensity Score Matching (PSM) Study
Changes in Mental Health and Preventive Behaviors before and after COVID-19 Vaccination: A Propensity Score Matching (PSM) Study Open
Mass vaccination against the COVID-19 pandemic is ongoing worldwide to achieve herd immunity among the general population. However, little is known about how the COVID-19 vaccination would affect mental health and preventive behaviors towa…
View article: Polymorphisms of TGFβ1T+869C and C-509T with Lung Cancer Risk: A Meta-analysis
Polymorphisms of TGFβ1T+869C and C-509T with Lung Cancer Risk: A Meta-analysis Open
This meta-analysis suggests that TGFβ1 T+869C and C-509T polymorphisms may not contribute to lung cancer risk in the total population, while the T+869C polymorphism may increase the risk of lung cancer in the Caucasian population. However,…
View article: Therapy-Emergent Drug Resistance to Integrase Strand Transfer Inhibitors in HIV-1 Patients: A Subgroup Meta-Analysis of Clinical Trials
Therapy-Emergent Drug Resistance to Integrase Strand Transfer Inhibitors in HIV-1 Patients: A Subgroup Meta-Analysis of Clinical Trials Open
Our results reveal that the DTG resistance rate was lower than the RAL resistance rate in a head-to-head comparison. Moreover, we confirmed that the EVG resistance rate was lower than the RAL resistance rate. In addition, our results revea…
View article: Knowledge, Attitude, and Behavior of Hepatitis B Virus Infection among Chinese Dental Interns
Knowledge, Attitude, and Behavior of Hepatitis B Virus Infection among Chinese Dental Interns Open
It is therefore recommended that Chinese dental interns continue improving knowledge level, assume more positive attitude by accumulating clinical experience, and pay more attention to the overlooked procedures. The results of the current …